Etonitazepyne

Etonitazepyne

Molecular structure via molpic based on CDK

Physical properties []
Molecular mass	394.5 g/mol ^[1]
Predicted LogP	4 ^[1]

Structural Identifiers []
Molecular formula	C₂₂H₂₆N₄O₃ ^[1]
IUPAC name	2-[(4-ethoxyphenyl)methyl]-5-nitro-1-(2-pyrrolidin-1-ylethyl)benzimidazole ^[1]
SMILES	CCOC1=CC=C(C=C1)CC2=NC3=C(N2CCN4CCCC4)C=CC(=C3)[N+](=O)[O-] ^[1]
InChI	InChI=1S/C22H26N4O3/c1-2-29-19-8-5-17(6-9-19)15-22-23-20-16-18(26(27)28)7-10-21(20)25(22)14-13-24-11-3-4-12-24/h5-10,16H,2-4,11-15H2,1H3 ^[1]
InChIKey	LQZWZCJCEPUKCJ-UHFFFAOYSA-N ^[1]

Etonitazepyne (also known as N-pyrrolidino etonitazene, 2-(4-Ethoxybenzyl)-5-nitro-1-(2-(pyrrolidin-1-yl)ethyl)-1h-benzo(d)imidazole, 2785346-75-8, Dea no. 9758, C22701 or 2-(4-ethoxybenzyl)-5-nitro-1-(2-(pyrrolidin-1-yl)ethyl)-1H-benzimidazole) is a opioid substance of the nitazepyne class.

Chemistry

Stereochemistry []

Etonitazepyne is a achiral mixture.

Reagents

There are currently 5 reagent-interactions on DrugsPRO

Reagent	Color change
Marquis
Mecke
Mandelin
Liebermann
Froehde

Subjective effects []

class / Opioid

Physical effects
Constipation Cough suppression Difficulty urinating Itchiness Nausea Pain relief Pupil constriction Respiratory depression Sedation Stomach cramp

Cognitive effects
Anxiety suppression Cognitive euphoria Compulsive redosing Increased music appreciation Thought deceleration

Visual effects
Double vision

External links []

References []

National Center for Biotechnology Information. PubChem Compound Summary for CID 155804760, Etonitazepyne. Accessed June 7, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/155804760
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Etonitazepyne. UNII: 8HY67JQ9ZH. Global Substance Registration System. Accessed June 7, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/8HY67JQ9ZH

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