3',4'-Methylenedioxy-α-pyrrolidinopentiophenone

MDPV, MDPK

Molecular structure via molpic based on CDK

Rotamer []

Conformer structure via 3Dmol.js

Physical properties []
Molecular mass	275.34 g/mol ^[1]
Appearance	White or light tan powder ^[1]
Melting point	MW 311.80; MP: 238-239 °C with decomposition; Soluble in chloroform, methanol, deionized water /3,4-Methylenedioxypyrovalerone hydrochloride/ ^[1]
Predicted LogP	3.3 ^[1]

Structural Identifiers []
Molecular formula	C₁₆H₂₁NO₃ ^[1]
IUPAC name	1-(1,3-benzodioxol-5-yl)-2-pyrrolidin-1-ylpentan-1-one ^[1]
SMILES	CCCC(C(=O)C1=CC2=C(C=C1)OCO2)N3CCCC3 ^[1]
InChI	InChI=1S/C16H21NO3/c1-2-5-13(17-8-3-4-9-17)16(18)12-6-7-14-15(10-12)20-11-19-14/h6-7,10,13H,2-5,8-9,11H2,1H3 ^[1]
InChIKey	SYHGEUNFJIGTRX-UHFFFAOYSA-N ^[1]

3',4'-Methylenedioxy-α-pyrrolidinopentiophenone (also known as Methylenedioxypyrovalerone, MDPV, 3,4-methylenedioxypyrovalerone, MDPK, (3,4)-methylenedioxypyrovalerone, 1-Pentanone, 1-(1,3-benzodioxol-5-yl)-2-(1-pyrrolidinyl)-, J2.658.826j, Chebi:233286, 1-(2H-1,3-benzodioxol-5-yl)-2-(pyrrolidin-1-yl)pentan-1-one or MPDV cpd) is a stimulant substance of the 3,4-methylenedioxyphenethylamine and pyrrolidinophenone class.

Chemistry

Stereochemistry []

3',4'-Methylenedioxy-α-pyrrolidinopentiophenone is a racemic mixture of the enantiomers.

Stereoisomerism
(R)-3',4'-Methylenedioxy-α-pyrrolidinopentiophenone (S)-3',4'-Methylenedioxy-α-pyrrolidinopentiophenone
Stereoisomer enumberation with rdkit

Druglikeness

Lipinski's rule of five

3',4'-Methylenedioxy-α-pyrrolidinopentiophenone matches Lipinski's rule of five.

Subjective effects []

class / Stimulant

Physical effects
Abnormal heartbeat Appetite suppression Dehydration Dry mouth Increased blood pressure Increased heart rate Increased libido Restless legs Shakiness Stamina enhancement Stimulation Teeth grinding Vasoconstriction

Cognitive effects
Analysis enhancement Cognitive euphoria Compulsive redosing Disinhibition Ego inflation Focus enhancement Increased music appreciation Mania Motivation enhancement Suggestibility suppression Thought acceleration Wakefulness

Legal status []

Australia: 3',4'-Methylenedioxy-α-pyrrolidinopentiophenone is a S9 substance.
Brazil: 3',4'-Methylenedioxy-α-pyrrolidinopentiophenone is a F1 substance.
Canada: 3',4'-Methylenedioxy-α-pyrrolidinopentiophenone is a Schedule I substance.
Germany: 3',4'-Methylenedioxy-α-pyrrolidinopentiophenone is a Anlage II substance.
United Kingdom: 3',4'-Methylenedioxy-α-pyrrolidinopentiophenone is a Class B substance.
United States: 3',4'-Methylenedioxy-α-pyrrolidinopentiophenone is a Schedule I under the "Controlled Substances Act (CSA)".
United Nations: 3',4'-Methylenedioxy-α-pyrrolidinopentiophenone is a Schedule II drug under the "Convention on Psychotropic Substances 1971".^[2]

External links []

References []

National Center for Biotechnology Information. PubChem Compound Summary for CID 20111961, 3',4'-Methylenedioxy-α-pyrrolidinopentiophenone. Accessed July 3, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/20111961
Substance Details 3,4-Methylenedioxypyrovalerone. Accessed July 3, 2026. https://www.unodc.org/LSS/Substance/Details/6a35fe21-2cdd-46ff-a343-cd977fa28ff6

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