Anodyne

DON
2,5-Dimethoxy-4-nitroamphetamine
Salts
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2,5-Dimethoxy-4-nitroamphetamine hydrochloride
2,5-Dimethoxy-4-nitroamphetamine hydrochloride
Molecular structure via molpic
Conformer structure via 3Dmol.js
Molecular formulaC11H16N2O4[1]
Molecular mass240.26 g/mol[1]
Predicted LogP1.7[1]
Chiralityracemic[2]
Identifiers
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IUPAC name1-(2,5-dimethoxy-4-nitrophenyl)propan-2-amine[1]
SMILESCC(CC1=CC(=C(C=C1OC)[N+](=O)[O-])OC)N[1]
InChIInChI=1S/C11H16N2O4/c1-7(12)4-8-5-11(17-3)9(13(14)15)6-10(8)16-2/h5-7H,4,12H2,1-3H3[1]
InChIKeyJQJRESSXOVAECC-UHFFFAOYSA-N[1]
Dosing

2,5-Dimethoxy-4-nitroamphetamine

2,5-Dimethoxy-4-nitroamphetamine (also known as 1-(2,5-Dimethoxy-4-nitrophenyl)-2-aminopropane, Don, J275.080E, L000870, 2-(2,5-Dimethoxy-4-nitro-phenyl)-1-methyl-ethylamine, Benzeneethanamine, 2,5-dimethoxy-α-methyl-4-nitro-, (-)2-(2,5-Dimethoxy-4-nitro-phenyl)-1-methyl-ethylamine, 2-(2,5-Dimethoxy-4-nitro-phenyl)-1-methyl-ethylamine(DON), -1-(2,5-Dimethoxy-4-nitrophenyl)-2-aminopropane or -1-(4-Nitro-2,5-dimethoxyphenyl)-2-aminopropane) is a psychedelic substance of the 2,5-dimethoxyphenethylamine class.

Chemistry

2,5-Dimethoxy-4-nitroamphetamine is typically found in the form of its hydrochloride salt.

Stereochemistry

(RS)-2,5-Dimethoxy-4-nitroamphetamine is a racemic mixture of the optical stereoisomers

See also

References

  1. National Center for Biotechnology Information. PubChem Compound Summary for CID 105432, 2,5-Dimethoxy-4-nitroamphetamine. Accessed June 17, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/105432.

  2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. 2,5-Dimethoxy-4-nitroamphetamine. UNII: 3FIV60666J. Global Substance Registration System. Accessed June 17, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/3FIV60666J