Anodyne

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25I-NBOMe
Generated by the Chemistry Development Kit (http://github.com/cdk)
Salts
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2,5-Dimethoxy-4-iodo-N-(2-methoxybenzyl)phenethylamine hydrochloride
Generated by the Chemistry Development Kit (http://github.com/cdk)
Molecular structure via molpic based on CDK
Physical properties
[]
427.3 g/mol [1]
3.8 [1]
Structural Identifiers
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C18H22INO3 [1]
2-(4-iodo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine [1]
COC1=CC=CC=C1CNCCC2=CC(=C(C=C2OC)I)OC [1]
InChI=1S/C18H22INO3/c1-21-16-7-5-4-6-14(16)12-20-9-8-13-10-18(23-3)15(19)11-17(13)22-2/h4-7,10-11,20H,8-9,12H2,1-3H3 [1]
InChIKeyZFUOLNAKPBFDIJ-UHFFFAOYSA-N [1]
Dosing
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Duration of actionInsufflation: 4 – 6 hSublingual administration|Sublingual: 6 – 10 hBuccal administration|Buccal: 6 – 10 h

2,5-Dimethoxy-4-iodo-N-(2-methoxybenzyl)phenethylamine

2,5-Dimethoxy-4-iodo-N-(2-methoxybenzyl)phenethylamine (also known as 25I-NBOMe, Cimbi-5, N-bomb, 11C-cimbi-5, 2C-I-NMBOMe, 2-(4-iodo-2,5-dimethoxyphenyl)-n-(2-methoxybenzyl)ethanamine, 2-(4-Iodo-2,5-dimethoxyphenyl)-N-((2-methoxyphenyl)methyl)ethanamine, RefChem:483983, 2C-I-NBOMe or 4-Iodo-2,5-dimethoxy-N-((2-methoxyphenyl)methyl)-benzeneethanamine) is a psychedelic substance of the n-benzylphenethylamine class.

Chemistry

Salts []

2,5-Dimethoxy-4-iodo-N-(2-methoxybenzyl)phenethylamine is typically found in the form of its hydrochloride salt.

 []

2,5-Dimethoxy-4-iodo-N-(2-methoxybenzyl)phenethylamine is a achiral mixture

Legal status []

  • Brazil: 2,5-Dimethoxy-4-iodo-N-(2-methoxybenzyl)phenethylamine is a F2 substance.[3]
  • United Kingdom: 2,5-Dimethoxy-4-iodo-N-(2-methoxybenzyl)phenethylamine is a Class A substance.
  • United States: 2,5-Dimethoxy-4-iodo-N-(2-methoxybenzyl)phenethylamine is a Schedule I under the "Controlled Substances Act (CSA)".
  • Germany: 2,5-Dimethoxy-4-iodo-N-(2-methoxybenzyl)phenethylamine is a Anlage I substance.
  • European Union: 2,5-Dimethoxy-4-iodo-N-(2-methoxybenzyl)phenethylamine is a Controlled substance.
  • Canada: 2,5-Dimethoxy-4-iodo-N-(2-methoxybenzyl)phenethylamine is a Schedule III substance.
  • United Nations: 2,5-Dimethoxy-4-iodo-N-(2-methoxybenzyl)phenethylamine is a Schedule I drug under the "Convention on Psychotropic Substances 1971".

See also []

  • Substituted N-benzylphenethylamines (x-NBx)
  • Anodyne

    • External links []

    References []

    1. National Center for Biotechnology Information. PubChem Compound Summary for CID 10251906, 2,5-Dimethoxy-4-iodo-N-(2-methoxybenzyl)phenethylamine. Accessed October 5, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/10251906

    2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. 2,5-Dimethoxy-4-iodo-N-(2-methoxybenzyl)phenethylamine. UNII: 547KGL06IP. Global Substance Registration System. Accessed October 5, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/547KGL06IP

    3. Anvisa. RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. July 24, 2023. Accessed October 5, 2025. https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-804-de-24-de-julho-de-2023-498447451