2C-B

Salts []
2,5-Dimethoxy-4-bromophenethylamine hydrochloride

2,5-Dimethoxy-4-bromophenethylamine hydrobromide

Molecular structure via molpic

Conformer structure via 3Dmol.js
Molecular formula	C₁₀H₁₄BrNO₂^[1]
Molecular mass	260.13 g/mol^[1]
Predicted LogP	2.1^[1]
Chirality	achiral^[2]

Identifiers []
IUPAC name	2-(4-bromo-2,5-dimethoxyphenyl)ethanamine^[1]
SMILES	COC1=CC(=C(C=C1CCN)OC)Br^[1]
InChI	InChI=1S/C10H14BrNO2/c1-13-9-6-8(11)10(14-2)5-7(9)3-4-12/h5-6H,3-4,12H2,1-2H3^[1]
InChIKey	YMHOBZXQZVXHBM-UHFFFAOYSA-N^[1]

Dosing
Elimination half-life	1.2–2.5 hours^[3]^[4]
Duration of action	Oral: 2–8 hours^[5]

2,5-Dimethoxy-4-bromophenethylamine

2,5-Dimethoxy-4-bromophenethylamine (also known as 4-Bromo-2,5-dimethoxyphenethylamine, 2-(4-Bromo-2,5-dimethoxyphenyl)ethylamine, BDMPEA, 2-(4-Bromo-2,5-dimethoxyphenyl)ethanamine, Benzeneethanamine, 4-bromo-2,5-dimethoxy-, Nexus, 4-Bromo-2,5dimethoxyphenethylamine, Bromo-2,5-dimethoxyphenylethylamine, Eros or Venus) is a psychedelic substance of the 2,5-dimethoxyphenethylamine class.

Chemistry

2,5-Dimethoxy-4-bromophenethylamine is typically found in the form of its hydrochloride and hydrobromide salts.

Stereochemistry

2,5-Dimethoxy-4-bromophenethylamine is a achiral mixture

Subjective effects

Legal status

Australia: 2,5-Dimethoxy-4-bromophenethylamine is a Schedule 9.
Brazil: 2,5-Dimethoxy-4-bromophenethylamine is a F2.
Canada: 2,5-Dimethoxy-4-bromophenethylamine is a Schedule III.
Germany: 2,5-Dimethoxy-4-bromophenethylamine is a Anlage I.
United Kingdom: 2,5-Dimethoxy-4-bromophenethylamine is a Class A.
United States: 2,5-Dimethoxy-4-bromophenethylamine is a Schedule I under the "Controlled Substances Act (CSA)".
United Nations: 2,5-Dimethoxy-4-bromophenethylamine is a Schedule II under the "Convention on Psychotropic Substances 1971".

External links

References

National Center for Biotechnology Information. PubChem Compound Summary for CID 98527, 2,5-Dimethoxy-4-bromophenethylamine. Accessed June 17, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/98527.
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. 2,5-Dimethoxy-4-bromophenethylamine. UNII: V77772N32H. Global Substance Registration System. Accessed June 17, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/V77772N32H
Papaseit E, Farré M, Pérez-Mañá C, Torrens M, Ventura M, Pujadas M, de la Torre R, González D. Acute Pharmacological Effects of 2C-B in Humans: An Observational Study. Frontiers in Pharmacology. 2018; 9:206.
Thomann J, Rudin D, Kraus S, Arikci D, Holze F, Liechti ME, Luethi D. LC–MS/MS-based pharmacokinetic and metabolic analysis of 4-bromo-2,5-dimethoxyphenethylamine (2C-B) and its metabolites in human plasma. Drug Metabolism and Disposition. 2025;
Inan F, Brunt TM, Contrucci RR, Hondebrink L, Franssen EJ. Novel Phenethylamines and Their Potential Interactions With Prescription Drugs: A Systematic Critical Review. Ther Drug Monit. April 1, 2020; 42(2):271–281.

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