{"Abbreviation":"","Aliases":["9H-Pyrido[3,4-B]indole","Norharman","Norharmane","2,9-Diazafluorene","Carbazoline","9H-β-carboline","2-Azacarbazole",".β.-Carboline","9H-Pyrido(3,4-B)indole","CCRIS 6915"],"CAS":"244-63-3","ChEBI":"CHEBI:109895","ChEMBL":"CHEMBL275224","ChemicalClasses":["β-carboline"],"Chirality":"achiral","Dosing Info":[],"DrugClasses":[],"EINECS":"205-959-0","European Community (EC) Number":"205-959-0","FullSalts":["β-Carboline hydrochloride"],"HMDB ID":"HMDB0012897","HeavyAtomCount":13,"IUPACName":"9H-pyrido[3,4-b]indole","InChI":"InChI=1S/C11H8N2/c1-2-4-10-8(3-1)9-5-6-12-7-11(9)13-10/h1-7,13H","InChIKey":"AIFRHYZBTHREPW-UHFFFAOYSA-N","IsClass":true,"MeSH Pharmacological Classification":"Chemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes. (See all compounds classified as Mutagens.)","Melting Point":"199 °C","MolecularFormula":"C\u003csub\u003e11\u003c/sub\u003eH\u003csub\u003e8\u003c/sub\u003eN\u003csub\u003e2\u003c/sub\u003e","MolecularWeight":"168.19 g/mol","Physical Description":"Solid","PrevSalts":["hydrochloride"],"PubChemId":64961,"Record Description":["Beta-carboline is the parent compound of the beta-carbolines, a tricyclic structure comprising an indole ring system ortho- fused to C-3 and C-4 of a pyridine ring. It has a role as a marine metabolite and a fungal metabolite. It is a member of beta-carbolines and a mancude organic heterotricyclic parent.","9H-Pyrido[3,4-B]indole has been reported in Polygala tenuifolia, Streptomyces nigra, and other organisms with data available.","Beta-carboline is the parent compound of the beta-carbolines, a tricyclic structure comprising an indole ring system ortho- fused to C-3 and C-4 of a pyridine ring. It has a role as a marine metabolite and a fungal metabolite. It is a member of beta-carbolines and a mancude organic heterotricyclic parent."],"References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/β-Carboline","Name":"β-Carboline","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q414226","Name":"β-Carboline","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/64961","Name":"β-Carboline","Sub":false}]},{"Name":"ChEMBL","Urls":[{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL275224","Name":"β-Carboline","Sub":false}]},{"Name":"ChEBI","Urls":[{"Link":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:109895","Name":"β-Carboline","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=244-63-3","Name":"β-Carboline","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0012897","Name":"β-Carboline","Sub":false}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/C20157","Name":"β-Carboline","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/94HMA1I78O","Name":"β-Carboline","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID2021070","Name":"β-Carboline","Sub":false}]}],"SMILES":"C1=CC=C2C(=C1)C3=C(N2)C=NC=C3","Salts":["hydrochloride"],"SaltsAcidCount":[1],"SaltsAmineCount":[1],"SaltsUNII":["XQ6N6T6H57"],"Solubility":"\u003e25.2 [ug/mL] (The mean of the results at pH 7.4)","StoreUNII":["94HMA1I78O"],"StructureBase64":"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