{"Abbreviation":[],"Aliases":["Benzenemethanol, 3-chloro-α-((1R)-1-((1,1-dimethylethyl)amino)ethyl)-, (αR)-rel-","RefChem:879173","rel-(αR)-3-Chloro-α-((1R)-1-((1,1-dimethylethyl)amino)ethyl)benzenemethanol","rac threo-Dihydrobupropion","rac threo-Dihydro Bupropion","(1S,2S)-2-(tert-Butylamino)-1-(3-chlorophenyl)propan-1-ol","Threo-dihydrobupropion","153365-82-3","(R*,R*)-3-Chloro-α-[1-[(1,1-dimethylethyl)amino]ethyl]benzenemethanol","Bupropion Impurity 71","S,S-threo-Hydrobupropion","Threohydrobupropion, (+-)-","264T829","102141-12-8","Benzenemethanol, 3-chloro-α-((1r)-1-((1,1-dimethylethyl)amino)ethyl)-, (αr)-rel-"],"CAS":"92264-82-9","ChemicalClasses":["amphetamine"],"Chirality":"achiral","Esters":[],"European Community (EC) Number":"689-762-9","Formating":[],"HeavyAtomCount":16,"IUPACName":"(1S,2S)-2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-ol","InChI":"InChI=1S/C13H20ClNO/c1-9(15-13(2,3)4)12(16)10-6-5-7-11(14)8-10/h5-9,12,15-16H,1-4H3/t9-,12+/m0/s1","InChIKey":"NDPTTXIBLSWNSF-JOYOIKCWSA-N","MolecularFormula":"C\u003csub\u003e13\u003c/sub\u003eH\u003csub\u003e20\u003c/sub\u003eClNO","MolecularWeight":"241.76 g/mol","Opticalactivity":"( + / - )","PubChemId":9834682,"RefCount":3,"RefCur":"","References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Threohydrobupropion","Name":"Threohydrobupropion","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q72518680","Name":"Threohydrobupropion","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/9834682","Name":"Threohydrobupropion","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=92264-82-9","Name":"Threohydrobupropion","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/988C8SFV4F","Name":"Threohydrobupropion","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID70431488","Name":"Threohydrobupropion","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 9834682, Threohydrobupropion. Accessed August 31, 2025. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/9834682\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/9834682\u003c/a\u003e","U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Threohydrobupropion. UNII: 988C8SFV4F. Global Substance Registration System. Accessed August 31, 2025. \u003ca href=https://gsrs.ncats.nih.gov/ginas/app/beta/substances/988C8SFV4F\u003ehttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/988C8SFV4F\u003c/a\u003e"],"SMILES":"C[C@@H]([C@H](C1=CC(=CC=C1)Cl)O)NC(C)(C)C","SaltData":[],"Salts":[],"StereoisomerData":[],"Stereoisomers":[],"Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 111.992 49.848\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#ff0d0d\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h112v50H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath fill=\"#000\" stroke=\"none\" d=\"M71.709 25.941h-.7l-1.75 15.24h4.2z\" class=\"bond\"/\u003e\u003cpath d=\"m71.359 25.941-13.198-7.62M58.161 18.321l-13.199 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m44.962 25.941-13.203-7.628M42.524 27.349l-10.765-6.22\"/\u003e\u003c/g\u003e\u003cpath d=\"m31.759 18.313-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m18.561 25.933.005 15.248M21 27.34l.004 12.434\"/\u003e\u003c/g\u003e\u003cpath d=\"m18.566 41.181 13.203 7.629\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m31.769 48.81 13.198-7.62M31.769 45.994l10.759-6.212\"/\u003e\u003c/g\u003e\u003cpath d=\"m44.962 25.941.005 15.249M18.561 25.933 6.875 19.188\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M57.811 18.321h.7\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"M57.56 16.144h1.201M57.31 13.967h1.701M57.06 11.79h2.201M56.81 9.613h2.701M56.56 7.435h3.201\"/\u003e\u003c/g\u003e\u003cpath d=\"m71.359 25.941 10.045-5.799M87.71 20.142l10.045 5.799M97.755 25.941l7.62-13.198M97.755 25.941l13.198 7.62M97.755 25.941l-7.62 13.198\" class=\"bond\"/\u003e\u003cpath fill=\"#1ff01f\" stroke=\"none\" d=\"M2.906 16.499q-.786 0-1.239.53-.452.524-.452 1.447 0 .91.417 1.446.422.53 1.268.53.321 0 .607-.054.291-.059.565-.142v.535q-.274.102-.565.149-.292.054-.697.054-.744 0-1.25-.31-.5-.309-.75-.875-.25-.571-.25-1.339 0-.745.268-1.31.274-.566.804-.881.529-.322 1.279-.322.78 0 1.352.286l-.244.524q-.226-.101-.506-.185-.274-.083-.607-.083m2.756 4.423h-.601v-5.215h.601z\" class=\"atom\"/\u003e\u003cg stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M60.42 3.078q0 .756-.256 1.328-.256.565-.756.881-.5.315-1.244.315-.757 0-1.263-.315-.506-.316-.756-.887-.244-.572-.244-1.334 0-.75.244-1.309.25-.566.756-.881T58.175.56q.733 0 1.233.316.5.309.756.875.256.565.256 1.327m-3.864 0q0 .923.387 1.459.393.53 1.221.53.839 0 1.22-.53.387-.536.387-1.459 0-.929-.387-1.452-.381-.524-1.209-.524-.833 0-1.226.524-.393.523-.393 1.452M64.726 5.531h-.619V3.245h-2.512v2.286h-.614v-4.9h.614v2.072h2.512V.631h.619z\"/\u003e\u003c/g\u003e\u003cg fill=\"#3050f8\" stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M86.498 20.771h-.721l-2.619-4.066h-.03l.03.595q.024.357.024.732v2.739h-.566v-4.9h.715l2.607 4.055h.03l-.018-.328-.024-.476q-.006-.262-.006-.482v-2.769h.578zM86.361 15.31h-.619v-2.286h-2.513v2.286h-.613v-4.9h.613v2.072h2.513V10.41h.619z\"/\u003e\u003c/g\u003e\u003cpath stroke=\"#1ff01f\" d=\"m6.875 19.188 5.843 3.372\" class=\"hi\"/\u003e\u003cpath stroke=\"#3050f8\" d=\"m81.404 20.142-5.023 2.899M81.404 20.142l-5.023 2.899M87.71 20.142l5.022 2.899M87.71 20.142l5.022 2.899\" class=\"hi\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Title":"Threohydrobupropion","UNII":"988C8SFV4F","Wikidata":"Q72518680","Wikipedia":"Threohydrobupropion","XLogP":2.7}