{"Abbreviation":[],"Absorption, Distribution and Excretion":"Oral administration of taurine was studied and it reported dose-dependent values of AUC, Cmax and tmax wherein a dose of 1-30 mg/kg ranged from 89-3452 mcg min/L, 2-15.7 mcg min/ml and 15 min respectively. Further studies in healthy individuals gave an AUC, Cmax and tmax in the range of 116-284.5 mg h/L, 59-112.6 mg/L and 1-2.5 h.","Aliases":["Taurine","107-35-7","Ethanesulfonic acid, 2-amino-","tauphon","2-Aminoethylsulfonic acid","2-Sulfoethylamine","aminoethylsulfonic acid","O-Due","2-aminoethane-1-sulfonic acid","Aminoethanesulfonic acid","taufon","β-Aminoethylsulfonic acid","Taurina","FEMA No. 3813","Taurinum","NCI-C60606","Taukard","1EQV5MLY3D","NSC-32428","Dtxsid3021304","Dtxcid301304","Chebi:15891","Taurine High","Taurine 7421","Taurine High 7422","203-483-8","2-azaniumylethanesulfonate","C2H7NO3S","CCRIS 4721","AI3-18307","2-aminoethane sulfonic acid","Einecs 203-483-8","Mfcd00008197","1-Aminoethane-2-sulfonic acid","NSC32428","Ncgc00015997-06","Aminoethylsulfonic acid","2-amino-ethanesulfonic acid","Cas-107-35-7","Smr000326743","Sr-01000076144","2-AminoethanesulfonicAcid","Unii-1eqv5mly3d","NSC 32428","Taurineold","Taurate","HSDB 8167","Taurine CRS","Aminoethylsulfonate","b-Aminoethylsulfonate","2-Aminoethylsulfonate","2-aminoethyl sulfonate","β-Aminoethylsulfonate","Tocris-0209","2aminoethanesulfonic acid","Taurine, \u003e=99%","b-Aminoethylsulfonic acid","2-amino-ethanesulfonicaci","Lopac-T-0625","2-aminoethylsulphonic acid","WLN: Z2SWQ","1-Aminoethane-2-sulfonate","bmse000120","bmse000805","bmse000863","Ec 203-483-8","Lopac0_001134","Schembl23068","Taurine, \u003e=98%, FG","Mls000859681","Mls001332383","Mls001332384","Schembl313193","Chembl239243","GTPL2379","orb1311013","Schembl28297002","Taurine, \u003e=99.0%","HMS2093L13","HMS2233D19","HMS3263D09","HMS3370J18","Pharmakon1600-01505463","Bb_sc-12990","HY-B0351","RKL10149","taurine; 2-aminoethanesulfonic acid","Tox21_110277","Tox21_202520","Tox21_501134","Bdbm50357220","EBC-03933","HB2658","MSK000067","NSC759150","s2008","STL197941","Akos005208848","Tox21_110277_1","CCG-205208","DB01956","FT29795","LP01134","NSC-759150","Sdccgsbi-0051101.p003","Taurine, BioUltra, \u003e=99.5%","Taurine, SAJ first grade, \u003e=98.5%","Ncgc00015997-01","Ncgc00015997-02","Ncgc00015997-03","Ncgc00015997-04","Ncgc00015997-05","Ncgc00015997-07","Ncgc00015997-08","Ncgc00015997-10","Ncgc00015997-20","Ncgc00024497-01","Ncgc00024497-02","Ncgc00024497-03","Ncgc00024497-04","Ncgc00024497-05","Ncgc00260069-01","Ncgc00261819-01","AS-13587","DA-67951","Nci60_002814","Sbi-0051101.p002","A0295","EU-0101134","NS00009343","En300-28228","C00245","D00047","D78121","T 0625","Ab00443712-07","Ab00443712_09","Ab00443712_10","F094516","Q207051","Sr-01000076144-1","Sr-01000076144-3","Sr-01000076144-5","Taurine, certified reference material, TraceCERT(R)","Brd-k51474575-001-10-4","Brd-k51474575-001-11-2","F2191-0280","Z248489432","Taurine, cell culture tested, meets USP testing specifications","Taurine, United States Pharmacopeia (USP) Reference Standard","Taurine, Pharmaceutical Secondary Standard; Certified Reference Material"],"Biological Half-Life":"Oral administration of taurine in healthy individuals gave a plasma elimination half-life that ranged from 0.7-1.4 h.","Boiling Point":"It decomposes before reaching boiling point (325ºC)","CAS":"107-35-7","Chemical Classes":"Biological Agents -\u003e Amino Acids and Derivatives","ChemicalClasses":[],"Chirality":"achiral","Color/Form":"Colorless crystals","Decomposition":"When heated to decomposition it emits very toxic fumes of SOx and NOx","Density":"Density = 1.7 g/cu cm g/cm\u003csup\u003e3\u003c/sup\u003e","Drug Indication":"The use of diet supplements containing taurine is indicated for the nutritional support of infants and young pediatric patients requiring total parenteral nutrition via central or peripheral routes. The usage of diet supplements containing taurine prevents nitrogen and weight loss or to treat negative nitrogen balance in pediatric patients where the alimentary tract cannot be done through oral, gastrostomy or jejunostomy administration, there is impaired gastrointestinal absorption or protein requirements are substantially increased.","Drug Warnings":"Pregnant women and nursing mothers should avoid taurine supplements unless recommended by their physicians. Those with congestive heart failure should only use taurine under medical supervision.","Esters":[],"European Community (EC) Number":"203-483-8","Formating":[],"HMDB ID":"HMDB0000251","HeavyAtomCount":7,"IUPACName":"2-aminoethanesulfonic acid","Impurities":"Taurine is a white crystalline powder that is almost odourless but with a slightly acidic taste. It contains by specification at least 98.0 % taurine in dried substance. Analysis of five batches of the active substance showed an average content of 99.5 +/- 0.1 % taurine and a loss on drying of 0.07 +/- 0.01 %.11 The final additive may be formulated by adding a maximum 0.8 % of an anti-caking agent (SiO2). Three batches of the additive were analysed for impurities, one batch with six replicate samples and another batch with three replicate samples. In all batches, sulphated ash was \u003c 0.06 % (in one batch residue on ignition 0.06 %), chloride \u003c 0.01 %, sulphate \u003c 0.01 %, ammonium salt \u003c 0.02 %, related substances \u003c 0.2 %, heavy metals (expressed as lead) \u003c 10 mg/kg and arsenic \u003c 1.0 mg/kg (two batches).","InChI":"InChI=1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)","InChIKey":"XOAAWQZATWQOTB-UHFFFAOYSA-N","Interactions":"It prevented the development of ethanol-induced hypertension in rats.","Mechanism of Action":"The diet supplements containing taurine function by replacing the missing nutriments in the body. Taurine, as a single agent, presents different functions like substrate for formation of bile salts, cell volume regulation, modulation of intracellular calcium, cytoprotection of central nervous system, etc.","Melting Point":"572 °","Metabolism/Metabolites":"Taurine can be metabolized by diverse organisms to form different types of metabolites derived from the original form of taurine. In the human, the pathways that form the metabolism of taurine are divided in the formation of 5-glutamyl-taurine by the action of the enzyme gamma-glutamyltransferase 6 or the formation of taurocholate by the action of the bile acid-CoA:amino acid N-acyltransferase.","MolecularFormula":"C\u003csub\u003e2\u003c/sub\u003eH\u003csub\u003e7\u003c/sub\u003eNO\u003csub\u003e3\u003c/sub\u003eS","MolecularWeight":"125.15 g/mol","Non-Human Toxicity Values":"LD50 Rats oral \u003e7000 mg/kg bw","Odor":"Odorless","Pharmacodynamics":"The diet supplements containing taurine are formulated as a well-tolerated nitrogen source for nutritional support. Administration of diet supplements regulates the level of plasma amino acid concentration, nitrogen balance, weight and serum protein concentration to reach normal values, thus improving the nutritional status.","Physical Description":"Large white crystals or white powder.","PubChemId":1123,"Records":{"UNII":{"Impurities":[]}},"RefChem":"6284","RefCount":3,"RefCur":"","References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Taurine","Name":"Taurine","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q106345481","Name":"Taurine","Sub":false}]},{"Name":"DrugBank","Urls":[{"Link":"https://go.drugbank.com/drugs/DB01956","Name":"Taurine","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/1123","Name":"Taurine","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=107-35-7","Name":"Taurine","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0000251","Name":"Taurine","Sub":false}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/C00245","Name":"Taurine","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/1EQV5MLY3D","Name":"Taurine","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021304","Name":"Taurine","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 1123, Taurine. Accessed December 25, 2025. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/1123\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/1123\u003c/a\u003e","U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Taurine. UNII: 1EQV5MLY3D. Global Substance Registration System. Accessed December 25, 2025. \u003ca href=https://gsrs.ncats.nih.gov/ginas/app/beta/substances/1EQV5MLY3D\u003ehttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/1EQV5MLY3D\u003c/a\u003e"],"SMILES":"C(CS(=O)(=O)O)N","SaltData":[],"Salts":[],"Solubility":"50 to 100 mg/mL at 74.3 °F (NTP, 1992)","Stability/Shelf Life":"Taurine (three batches, stored in polyethylene sealed bags) was demonstrated to have a shelf-life of 36 months at 25 geg C. Shelf-life was measured under accelerated conditions at 40 °C and no loss was observed for six months (three batches).","StereoisomerData":[],"Stereoisomers":[],"Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 69.777 36.642\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#ff0d0d\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h70v37H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"m45.225 5.123-7.62 13.198M37.605 18.321H25.282\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M23.585 22.239v7.401M21.146 22.239v7.401\"/\u003e\u003cpath stroke=\"#c6c62c\" d=\"M23.585 22.239v3.701\" class=\"hi\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"M23.585 29.64v-3.7\" class=\"hi\"/\u003e\u003cpath stroke=\"#c6c62c\" d=\"M21.146 22.239v3.701\" class=\"hi\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"M21.146 29.64v-3.7\" class=\"hi\"/\u003e\u003c/g\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M21.146 14.403V7.002M23.585 14.403V7.002\"/\u003e\u003cpath stroke=\"#c6c62c\" d=\"M21.146 14.403v-3.7\" class=\"hi\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"M21.146 7.002v3.701\" class=\"hi\"/\u003e\u003cpath stroke=\"#c6c62c\" d=\"M23.585 14.403v-3.7\" class=\"hi\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"M23.585 7.002v3.701\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath d=\"M19.45 18.321h-8.665M45.225 5.123h11.9\" class=\"bond\"/\u003e\u003cpath fill=\"#c6c62c\" stroke=\"none\" d=\"M23.91 19.458q0 .649-.476 1.018-.47.363-1.268.363-.417 0-.768-.065-.345-.06-.577-.173v-.589q.244.113.607.202.369.09.762.09.547 0 .827-.215.28-.214.28-.577 0-.238-.107-.399-.101-.167-.351-.31t-.697-.297q-.625-.227-.946-.554-.316-.333-.316-.899 0-.393.197-.667.202-.279.553-.428.357-.155.816-.155.405 0 .738.077.339.072.613.197l-.196.53q-.25-.113-.548-.185-.298-.077-.625-.077-.458 0-.691.196-.232.197-.232.518 0 .244.101.411.108.167.34.298.232.125.631.279.428.155.726.34.298.178.452.434.155.25.155.637\" class=\"atom\"/\u003e\u003cpath stroke=\"none\" d=\"M24.625 33.558q0 .756-.256 1.328-.256.565-.756.881-.5.315-1.245.315-.756 0-1.262-.315-.506-.316-.756-.887-.244-.572-.244-1.334 0-.75.244-1.309.25-.566.756-.881t1.274-.316q.733 0 1.233.316.5.309.756.875.256.565.256 1.327m-3.864 0q0 .923.387 1.459.393.53 1.22.53.84 0 1.221-.53.387-.536.387-1.459 0-.929-.387-1.452-.381-.524-1.209-.524-.833 0-1.226.524-.393.523-.393 1.452M24.625 3.078q0 .756-.256 1.328-.256.565-.756.881-.5.315-1.245.315-.756 0-1.262-.315-.506-.316-.756-.887-.244-.572-.244-1.334 0-.75.244-1.309.25-.566.756-.881T22.38.56q.733 0 1.233.316.5.309.756.875.256.565.256 1.327m-3.864 0q0 .923.387 1.459.393.53 1.22.53.84 0 1.221-.53.387-.536.387-1.459 0-.929-.387-1.452-.381-.524-1.209-.524-.833 0-1.226.524-.393.523-.393 1.452\" class=\"atom\"/\u003e\u003cg stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M9.385 18.318q0 .756-.256 1.328-.256.565-.756.881-.5.315-1.245.315-.756 0-1.262-.315-.506-.316-.756-.887-.244-.572-.244-1.334 0-.75.244-1.309.25-.566.756-.881T7.14 15.8q.733 0 1.233.316.5.309.756.875.256.565.256 1.327m-3.864 0q0 .923.387 1.459.393.53 1.22.53.84 0 1.221-.53.387-.536.387-1.459 0-.929-.387-1.452-.381-.524-1.209-.524-.833 0-1.226.524-.393.523-.393 1.452M4.305 20.771h-.62v-2.286H1.173v2.286H.56v-4.9h.613v2.072h2.512v-2.072h.62z\"/\u003e\u003c/g\u003e\u003cg fill=\"#3050f8\" stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M62.406 7.573h-.72l-2.62-4.066h-.029l.029.595q.024.357.024.732v2.739h-.565v-4.9h.714l2.608 4.054h.029l-.018-.327-.023-.476q-.006-.262-.006-.483V2.673h.577zM66.712 7.573h-.619V5.287h-2.512v2.286h-.613v-4.9h.613v2.072h2.512V2.673h.619zM69.217 9.062h-1.943v-.3l.772-.779q.221-.221.371-.393.154-.175.232-.339.079-.168.079-.364 0-.243-.147-.368-.143-.129-.371-.129-.214 0-.379.075-.161.075-.328.208l-.193-.243q.171-.147.393-.247.225-.1.507-.1.411 0 .65.207t.239.575q0 .229-.096.433-.093.2-.265.396-.167.197-.392.418l-.615.604v.017h1.486z\"/\u003e\u003c/g\u003e\u003cpath stroke=\"#c6c62c\" d=\"M25.282 18.321h6.162M19.45 18.321h-4.333\" class=\"hi\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"M10.785 18.321h4.332M10.785 18.321h4.332\" class=\"hi\"/\u003e\u003cpath stroke=\"#3050f8\" d=\"M57.125 5.123h-5.95\" class=\"hi\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Taste":"Slightly acidic taste","Therapeutic Uses":"Taurine may be helpful in some with congestive heart failure and hypertension. It has demonstrated some antiatherogenic effects in both animal and human studies.","Title":"Taurine","UNII":"1EQV5MLY3D","Wikidata":"Q106345481","Wikipedia":"Taurine","XLogP":-4.1,"pH":"pH = 4.1-5.6 (5% aqueous solution)"}