{"Abbreviation":"5-HT","Aliases":["3-(2-Aminoethyl)-1H-indol-5-ol","Enteramine","Thrombotonin","Antemovis","Serotonine","Ds substance","Antemoqua","Hippophain","Substance DS","Substanz DS"],"CAS":"50-67-9","ChEBI":"CHEBI:28790","ChEMBL":"CHEMBL39","ChemicalClasses":["tryptamine"],"Chirality":"achiral","Dosing Info":[],"DrugClasses":["antidepressant","depressant"],"EINECS":"200-058-9","Esters":["propionate"],"European Community (EC) Number":"200-058-9","FullSalts":["Serotonin hydrochloride","Serotonin adipate"],"HMDB ID":"HMDB0000259","HeavyAtomCount":13,"IUPACName":"3-(2-aminoethyl)-1H-indol-5-ol","InChI":"InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2","InChIKey":"QZAYGJVTTNCVMB-UHFFFAOYSA-N","MeSH Pharmacological Classification":"Endogenous compounds and drugs that bind to and activate SEROTONIN RECEPTORS. Many serotonin receptor agonists are used as ANTIDEPRESSANTS; ANXIOLYTICS; and in the treatment of MIGRAINE DISORDERS. (See all compounds classified as Serotonin Receptor Agonists.)","MolecularFormula":"C\u003csub\u003e10\u003c/sub\u003eH\u003csub\u003e12\u003c/sub\u003eN\u003csub\u003e2\u003c/sub\u003eO","MolecularWeight":"176.21 g/mol","Physical Description":"Solid","PrevSalts":["hydrochloride","adipate"],"PubChemId":5202,"Record Description":["Serotonin is a primary amino compound that is the 5-hydroxy derivative of tryptamine. It has a role as a human metabolite, a mouse metabolite and a neurotransmitter. It is a monoamine molecular messenger, a primary amino compound, a member of phenols, a member of hydroxyindoles and a member of tryptamines. It is functionally related to a tryptamine. It is a conjugate base of a serotonin(1+).","For temporary relief of nervousness, anxiety, mood swings, joint pains, weakness, drowsiness, itching and lethargy. Not evaluated by the FDA, homeopathic product.","Serotonin has been reported in Mamestra brassicae, Bufo gargarizans, and other organisms with data available.","SEROTONIN is a small molecule drug with a maximum clinical trial phase of III and has 1 investigational indication.","A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.","See also: Serotonin Hydrochloride (active moiety of); Serotonin; tryptophan (component of); Acetylcholine Chloride; Histamine; Serotonin (component of) ... View More ...","Serotonin is a primary amino compound that is the 5-hydroxy derivative of tryptamine. It has a role as a human metabolite, a mouse metabolite and a neurotransmitter. It is a monoamine molecular messenger, a primary amino compound, a member of phenols, a member of hydroxyindoles and a member of tryptamines. It is functionally related to a tryptamine. It is a conjugate base of a serotonin(1+)."],"References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Serotonin","Name":"Serotonin","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q167934","Name":"Serotonin","Sub":false}]},{"Name":"DrugBank","Urls":[{"Link":"https://go.drugbank.com/drugs/DB08839","Name":"Serotonin","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/5202","Name":"Serotonin","Sub":false}]},{"Name":"ChemSpider","Urls":[{"Link":"https://www.chemspider.com/Chemical-Structure.5013.html","Name":"Serotonin","Sub":false}]},{"Name":"ChEMBL","Urls":[{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL39","Name":"Serotonin","Sub":false}]},{"Name":"ChEBI","Urls":[{"Link":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:28790","Name":"Serotonin","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=50-67-9","Name":"Serotonin","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0000259","Name":"Serotonin","Sub":false}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/C00780","Name":"Serotonin","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/333DO1RDJY","Name":"Serotonin","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID8075330","Name":"Serotonin","Sub":false}]}],"SMILES":"C1=CC2=C(C=C1O)C(=CN2)CCN","Salts":["hydrochloride","adipate"],"SaltsAcidCount":[1,1],"SaltsAmineCount":[1,1],"SaltsUNII":["GKN429M9VS","AAJ8D63BQY"],"Scheduling":[],"Solubility":"25.5 mg/mL","StoreUNII":["333DO1RDJY"],"StructureBase64":"<svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" height="62.782mm" version="1.2" viewBox="0 0 94.303 62.782" width="94.303mm">
      
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