{"Abbreviation":["PCPy"],"Aliases":["1-(1-Phenylcyclohexyl)pyrrolidine","PCPy","Roliciclidina","Rolicyclidinum","Dtxsid8046167","Dtxcid6026167","Chebi:60805","PHP (1-(1-phenylcyclohexyl)pyrrolidine)","Pyrrolidine, 1-(1-phenylcyclohexyl)-","Ncgc00160464-01","DEA No. 7458","Schembl517928","Unii-183o9o9je3","Chembl1719398","HSDB 7636","1-(1-phenylcyclohexyl)-pyrrolidine","Tox21_111832","Pyrrolidine, 1-(1-phenylcyclohexyl)","DB01549","Cas-2201-39-0","DB-362666","NS00068470","D12706"],"CAS":"2201-39-0","ChemicalClasses":["arylcyclohexylpyrrolidine"],"Chirality":"achiral","Drug Indication":"Rolicyclidine has anesthetic properties and can induce a sedative effect.","Erowid Experience Reports":[],"Esters":[],"Formating":[],"HeavyAtomCount":17,"IUPACName":"1-(1-phenylcyclohexyl)pyrrolidine","InChI":"InChI=1S/C16H23N/c1-3-9-15(10-4-1)16(11-5-2-6-12-16)17-13-7-8-14-17/h1,3-4,9-10H,2,5-8,11-14H2","InChIKey":"FYOWWXMGDATDQY-UHFFFAOYSA-N","KEGG Entries":[{"Id":"D12706","Interactions":[],"Synonyms":["Rolicyclidine"]}],"MeSH Headers":[{"Id":"M0075236","Link":"https://id.nlm.nih.gov/mesh/M0075236.html","Name":"1-(1-phenylcyclohexyl)pyrrolidine","Ref":25},{"Id":"DescTree","Link":"https://www.nlm.nih.gov/mesh/meshhome.html","Name":"MeSH Tree","Ref":27},{"Id":"PubMed from MeSH","Link":"https://www.nlm.nih.gov/mesh/meshhome.html","Name":null,"Ref":38}],"Mechanism of Action":"Rolicyclidine works primarily as an NMDA receptor antagonist, which blocks the activity of the NMDA Receptor.","MolecularFormula":"C\u003csub\u003e16\u003c/sub\u003eH\u003csub\u003e23\u003c/sub\u003eN","MolecularWeight":"229.36 g/mol","Pharmacodynamics":"Rolicyclidine is similar in effects to phencyclidine but is slightly less potent and has less stimulant effects. Instead it acts by inducing a sedative effect described as being somewhat similar to a barbiturate, but with additional PCP-like dissociative, anaesthetic and hallucinogenic effects.","PubChemId":62436,"Records":{"UNII":{"Impurities":[]}},"RefChem":"179781","RefCount":4,"RefCur":"","References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Rolicyclidine","Name":"Rolicyclidine","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q570183","Name":"Rolicyclidine","Sub":false}]},{"Name":"DrugBank","Urls":[{"Link":"https://go.drugbank.com/DB01549","Name":"Rolicyclidine","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/62436","Name":"Rolicyclidine","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=2201-39-0","Name":"Rolicyclidine","Sub":false}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/D12706","Name":"Rolicyclidine","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/183O9O9JE3","Name":"Rolicyclidine","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID8046167","Name":"Rolicyclidine","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 62436, Rolicyclidine. Accessed May 6, 2026. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/62436\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/62436\u003c/a\u003e","U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Rolicyclidine. UNII: 183O9O9JE3. Global Substance Registration System. Accessed May 6, 2026. \u003ca href=https://gsrs.ncats.nih.gov/ginas/app/beta/substances/183O9O9JE3\u003ehttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/183O9O9JE3\u003c/a\u003e","Anvisa. RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. July 24, 2023. Accessed May 6, 2026. \u003ca href=https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-804-de-24-de-julho-de-2023-498447451\u003ehttps://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-804-de-24-de-julho-de-2023-498447451\u003c/a\u003e"],"SMILES":"C1CCC(CC1)(C2=CC=CC=C2)N3CCCC3","SaltData":[],"Salts":[],"Scheduling":[{"gov":"Australia","ref":[],"schedule":"S9 substance"},{"gov":"Brazil","ref":["3"],"schedule":"F2 substance"},{"gov":"Canada","ref":[],"schedule":"Schedule III substance"},{"gov":"United Kingdom","ref":[],"schedule":"Class A substance"},{"act":"Controlled Substances Act (CSA)","gov":"United States","ref":[],"schedule":"Schedule I"},{"gov":"Germany","ref":[],"schedule":"Anlage I substance"},{"act":"Convention on Psychotropic Substances 1971","gov":"United Nations","ref":[],"schedule":"Schedule I drug"}],"StereoisomerData":[],"Stereoisomers":[],"Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 67.4 70.225\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#3050f8\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h68v71H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"m35.631 69.187 13.197-7.623M48.828 61.564l.006-15.24M48.834 46.324l-13.19-7.617M35.644 38.707 22.448 46.33M22.448 46.33l-.007 15.24M35.631 69.187l-13.19-7.617M35.644 38.707 25.852 27.04\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m10.845 29.693 15.007-2.653M11.807 27.046l12.236-2.162\"/\u003e\u003c/g\u003e\u003cpath d=\"M10.845 29.693 1.053 18.026\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m6.269 3.706-5.216 14.32M8.078 5.862 3.826 17.537\"/\u003e\u003c/g\u003e\u003cpath d=\"m6.269 3.706 15.007-2.653\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M31.068 12.72 21.276 1.053M28.295 13.209l-7.981-9.51\"/\u003e\u003c/g\u003e\u003cpath d=\"m25.852 27.04 5.216-14.32M35.644 38.707l6.95-8.283M48.772 27.271l11.819.82M60.591 28.091l5.756-14.126M66.347 13.965l-11.669-9.79M54.678 4.175l-12.911 8.121M44.487 23.23l-2.72-10.934\" class=\"bond\"/\u003e\u003cpath stroke=\"none\" d=\"M47.376 29.489h-.721l-2.619-4.066h-.03l.03.595q.024.357.024.732v2.739h-.566v-4.9h.715l2.607 4.054h.03l-.018-.327-.024-.476q-.006-.262-.006-.483v-2.768h.578z\" class=\"atom\"/\u003e\u003cpath stroke=\"#3050f8\" d=\"m42.594 30.424-3.475 4.142M48.772 27.271l5.909.41M44.487 23.23l-1.36-5.467\" class=\"hi\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Title":"Rolicyclidine","UNII":"183O9O9JE3","Wikidata":"Q570183","Wikipedia":"Rolicyclidine","XLogP":3.3}