{"Abbreviation":"","Aliases":["Pirovalerona","Pyrovaleronum","4'-Methyl-2-(1-pyrrolidinyl)valerophenone","1-Pentanone, 1-(4-methylphenyl)-2-(1-pyrrolidinyl)-","J8.659B","Valerophenone, 4'-methyl-2-(1-pyrrolidinyl)-","1-(4-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one","1-P-tolyl-1-oxo-2-pyrrolidino-n-pentane","1-(4-methylphenyl)-2-(pyrrolidin-1-yl)pentan-1-one","DAA56349"],"CAS":"3563-49-3","ChEBI":"CHEBI:134998","ChEMBL":"CHEMBL201960","ChemicalClasses":["pyrrolidinophenone"],"Chirality":"racemic","Classes":["Stimulant"],"DEA no":1485,"Dosing Info":[],"DrugClasses":["stimulant"],"European Community (EC) Number":"803-642-7","FullSalts":["Pyrovalerone hydrochloride"],"HMDB ID":"HMDB0256994","HeavyAtomCount":18,"IUPACName":"1-(4-methylphenyl)-2-pyrrolidin-1-ylpentan-1-one","InChI":"InChI=1S/C16H23NO/c1-3-6-15(17-11-4-5-12-17)16(18)14-9-7-13(2)8-10-14/h7-10,15H,3-6,11-12H2,1-2H3","InChIKey":"SWUVZKWCOBGPTH-UHFFFAOYSA-N","MeSH Pharmacological Classification":"A loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. They work by a variety of mechanisms, but usually not by direct excitation of neurons. The many drugs that have such actions as side effects to their main therapeutic use are not included here. (See all compounds classified as Central Nervous System Stimulants.)","MolecularFormula":"C\u003csub\u003e16\u003c/sub\u003eH\u003csub\u003e23\u003c/sub\u003eNO","MolecularWeight":"245.36 g/mol","Opticalactivity":"( + / - )","PrevSalts":["hydrochloride"],"PubChemId":14373,"Record Description":["Pyrovalerone is an aromatic ketone.","Pyrovalerone is a DEA Schedule V controlled substance. Substances in the DEA Schedule V have a low potential for abuse relative to substances listed in Schedule IV and consist primarily of preparations containing limited quantities of certain narcotics. It is a Stimulants substance.","PYROVALERONE is a small molecule drug with a maximum clinical trial phase of IV.","Pyrovalerone is an aromatic ketone.","Wikipedia|List of designer drugs|Stimulants|Pyrrolidines and Pyrrolidinophenones"],"References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Pyrovalerone","Name":"Pyrovalerone","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q410824","Name":"Pyrovalerone","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/14373","Name":"Pyrovalerone","Sub":false}]},{"Name":"ChEMBL","Urls":[{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL201960","Name":"Pyrovalerone","Sub":false}]},{"Name":"ChEBI","Urls":[{"Link":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:134998","Name":"Pyrovalerone","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=3563-49-3","Name":"Pyrovalerone","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0256994","Name":"Pyrovalerone","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/VOU69C02JP","Name":"Pyrovalerone","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID20863194","Name":"Pyrovalerone","Sub":false}]}],"SMILES":"CCCC(C(=O)C1=CC=C(C=C1)C)N2CCCC2","Salts":["hydrochloride"],"SaltsAcidCount":[1],"SaltsAmineCount":[1],"SaltsUNII":["Z95Z9C2201"],"Scheduling":[{"gov":"Australia","schedule":"S4 substance"},{"gov":"Brazil","schedule":"B1 substance"},{"gov":"Canada","schedule":"Schedule IV substance"},{"gov":"United States","schedule":"Schedule V substance"},{"gov":"United Kingdom","schedule":"Class C substance"},{"gov":"Germany","schedule":"Anlage II substance"}],"StereoisomerRacemic":"(RS)-Pyrovalerone","StoreUNII":["VOU69C02JP"],"StructureBase64":"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Effects":{"Cognitive Effects":["Analysis enhancement","Ego inflation","Focus enhancement","Increased music appreciation","Motivation enhancement","Thought acceleration","Wakefulness","Disinhibition","Suggestibility suppression","Cognitive euphoria","Compulsive redosing","Mania"],"Physical Effects":["Increased libido","Stamina enhancement","Stimulation","Appetite suppression","Dehydration","Dry mouth","Restless legs","Shakiness","Teeth grinding","Abnormal heartbeat","Increased blood pressure","Increased heart rate","Vasoconstriction"],"Sensory Effects":[]},"Title":"Pyrovalerone","UNII":"VOU69C02JP","Wikidata":"Q410824","Wikipedia":"Pyrovalerone","XLogP":3.8}