{"ATC Code":"D - Dermatologicals","Abbreviation":"","Aliases":["Proazamine","Protazine","Promethazin","Prometazin","Vallergine","Dimapp","Fargan","Procit","Promazinamide","Promezathine","Phenargan","Diprazine","Histargan","Phargan","Tanidil","Thiergan","Pyrethiazine","Prometazina","Lilly 1516","Antiallersin","Fenetazine","Phenerzine","Pipolphene","Proazaimine","Prometasin"],"Biological Half-Life":"The elimination half life of promethazine is approximately 12-15h.","Boiling Point":"374 to 379 °F at 3 mmHg (NTP, 1992)","CAS":"60-87-7","ChEBI":"CHEBI:8461","ChEMBL":"CHEMBL643","ChemicalClasses":["ethylamine"],"Color/Form":"Crystals","Decomposition":"When heated to decomposition it emits very toxic fumes of /nitrogen oxides and sulfur oxides/.","Drug Classes":"Breast Feeding; Lactation; Antiemetics; Phenothiazines","Drug Indication":"Promethazine tablets and suppositories are indicated to treat rhinitis, allergic conjunctivitis, allergic reactions to blood or plasma, dermographism, anaphylactic reactions, sedation, nausea, vomiting, pain, motion sickness, and allergic skin reactions. Promethazine cough syrup with phenylephrine and codeine is indicated to relieve cough and upper respiratory symptoms, and nasal congestion associated with allergy or the common cold.","Drug Warnings":"/BOXED WARNING/ WARNING: Respiratory Depression - Pediatrics. /Promethazine/ injection should not be used in pediatric patients less than 2 years of age because of the potential for fatal respiratory depression. Postmarketing cases of respiratory depression, including fatalities, have been reported with use of promethazine in pediatric patients less than 2 years of age. Caution should be exercised when administering promethazine injection to pediatric patients 2 years of age and older.","EINECS":"200-489-2","Esters":[],"European Community (EC) Number":"200-489-2","FDA Pharmacological Classification":"FF28EJQ494","Formating":[],"HMDB ID":"HMDB0015202","HeavyAtomCount":20,"Human Drugs":"Breast Feeding; Lactation; Antiemetics; Phenothiazines","IUPACName":"N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine","InChI":"InChI=1S/C17H20N2S/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19/h4-11,13H,12H2,1-3H3","InChIKey":"PWWVAXIEGOYWEE-UHFFFAOYSA-N","MeSH Pharmacological Classification":"Agents that are used to treat allergic reactions. Most of these drugs act by preventing the release of inflammatory mediators or inhibiting the actions of released mediators on their target cells. (From AMA Drug Evaluations Annual, 1994, p475) (See all compounds classified as Anti-Allergic Agents.)","Melting Point":"140 °","MolecularFormula":"C\u003csub\u003e17\u003c/sub\u003eH\u003csub\u003e20\u003c/sub\u003eN\u003csub\u003e2\u003c/sub\u003eS","MolecularWeight":"284.4 g/mol","Pharmacodynamics":"Promethazine is is a histamine H1 antagonist that can be used for it's ability to induce sedation, reduce pain, and treat allergic reactions. Promethazine's effects generally last 4-6h but can last up to 12h. Patients should be counselled regarding CNS and respiratory depression, reduce seizure threshold, and bone marrow depression.","Physical Description":"Crystals. Melting point 60 °C. Used as an antihistamine.","PubChemId":4927,"RefCount":2,"RefCur":"","References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Promethazine","Name":"Promethazine","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q422970","Name":"Promethazine","Sub":false}]},{"Name":"DrugBank","Urls":[{"Link":"https://go.drugbank.com/drugs/DB01069","Name":"Promethazine","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/4927","Name":"Promethazine","Sub":false}]},{"Name":"ChEMBL","Urls":[{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL643","Name":"Promethazine","Sub":false}]},{"Name":"ChEBI","Urls":[{"Link":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:8461","Name":"Promethazine","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=60-87-7","Name":"Promethazine","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0015202","Name":"Promethazine","Sub":false}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/C07404","Name":"Promethazine","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/FF28EJQ494","Name":"Promethazine","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID7023518","Name":"Promethazine","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 4927, Promethazine. Accessed July 7, 2025. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/4927\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/4927\u003c/a\u003e"],"Reported Fatal Dose":"3(?). 3= MODERATELY TOXIC: PROBABLE ORAL LETHAL DOSE (HUMAN) 0.5-5 G/KG, BETWEEN 1 OZ \u0026 1 PINT (OR 1 LB) FOR 70 KG PERSON (150 LB).","SMILES":"CC(CN1C2=CC=CC=C2SC3=CC=CC=C31)N(C)C","SaltData":[],"Salts":[],"Solubility":"Very soluble in dilute hydrogen chloride","Stability/Shelf Life":"In general, promethazine HCl exhibits increasing stability with decreasing pH. /Promethazine HCl/","StereoisomerData":[],"Stereoisomers":["(+)-Promethazine","(-)-Promethazine"],"Structure":"\u003csvg  preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 81.28 80.274\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#3050f8\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h82v81H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"m67.022 31.501-13.191-7.616M53.831 23.885 40.64 31.501M40.64 31.501v11.382M37.487 48.552l-10.048 5.797\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m27.439 54.349-13.2-7.616M25.001 55.757l-10.762-6.209\"/\u003e\u003c/g\u003e\u003cpath d=\"M14.239 46.733 1.038 54.349\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M1.038 54.349V69.58M3.477 55.757v12.415\"/\u003e\u003c/g\u003e\u003cpath d=\"m1.038 69.58 13.201 7.616\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m14.239 77.196 13.2-7.616M14.239 74.381l10.762-6.209\"/\u003e\u003c/g\u003e\u003cpath d=\"M27.439 54.349V69.58M27.439 69.58l10.489 6.051M43.337 75.64l10.504-6.06\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m53.841 69.58 13.2 7.616M56.279 68.172l10.762 6.209\"/\u003e\u003c/g\u003e\u003cpath d=\"m67.041 77.196 13.201-7.616\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M80.242 69.58V54.349M77.804 68.172V55.757\"/\u003e\u003c/g\u003e\u003cpath d=\"m80.242 54.349-13.201-7.616\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m67.041 46.733-13.2 7.616M67.041 49.548l-10.762 6.209\"/\u003e\u003c/g\u003e\u003cpath d=\"M53.841 69.58V54.349M43.794 48.552l10.047 5.797M53.831 23.885V12.504M56.984 6.833l10.038-5.795M50.678 6.833 40.64 1.038\" class=\"bond\"/\u003e\u003cpath stroke=\"none\" d=\"M42.581 49.183h-.72l-2.62-4.066h-.03l.03.595q.024.357.024.732v2.739h-.566v-4.9h.715l2.607 4.054h.03l-.018-.327-.024-.477q-.006-.261-.006-.482v-2.768h.578z\" class=\"atom\"/\u003e\u003cpath fill=\"#c6c62c\" stroke=\"none\" d=\"M42.185 78.333q0 .649-.476 1.018-.471.363-1.268.363-.417 0-.768-.065-.346-.06-.578-.173v-.589q.244.113.608.202.369.089.762.089.547 0 .827-.214t.28-.578q0-.238-.107-.398-.102-.167-.352-.31t-.696-.298q-.625-.226-.947-.553-.315-.334-.315-.899 0-.393.196-.667.203-.28.554-.429.357-.154.815-.154.405 0 .739.077.339.072.613.197l-.197.529q-.25-.113-.547-.184-.298-.078-.625-.078-.459 0-.691.197-.232.196-.232.518 0 .244.101.411.107.166.339.297.233.125.631.28.429.155.727.339.297.179.452.435.155.25.155.637\" class=\"atom\"/\u003e\u003cpath stroke=\"none\" d=\"M55.772 11.104h-.721l-2.619-4.066h-.03l.03.595q.024.357.024.732v2.739h-.566v-4.9h.715l2.607 4.054h.03l-.018-.327-.024-.476q-.006-.262-.006-.483V6.204h.578z\" class=\"atom\"/\u003e\u003cpath stroke=\"#3050f8\" d=\"M40.64 42.883v-5.691M37.487 48.552l-5.024 2.898\" class=\"hi\"/\u003e\u003cpath stroke=\"#c6c62c\" d=\"m37.928 75.631-5.245-3.025M43.337 75.64l5.252-3.03\" class=\"hi\"/\u003e\u003cpath stroke=\"#3050f8\" d=\"m43.794 48.552 5.023 2.898M53.831 12.504v5.691M56.984 6.833l5.019-2.897M50.678 6.833l-5.019-2.897\" class=\"hi\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","StructureBase64":"<svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" height="80.274mm" version="1.2" viewBox="0 0 81.28 80.274" width="81.28mm">
      
    <desc>Generated by the Chemistry Development Kit (http://github.com/cdk)</desc>
      
    <g fill="#3050F8" stroke="#000000" stroke-linecap="round" stroke-linejoin="round" stroke-width=".7">
            
        <rect fill="#FFFFFF" height="81.0" stroke="none" width="82.0" x=".0" y=".0"/>
            
        <g class="mol" id="mol1">
                  
            <line class="bond" id="mol1bnd1" x1="67.022" x2="53.831" y1="31.501" y2="23.885"/>
                  
            <line class="bond" id="mol1bnd2" x1="53.831" x2="40.64" y1="23.885" y2="31.501"/>
                  
            <line class="bond" id="mol1bnd3" x1="40.64" x2="40.64" y1="31.501" y2="42.883"/>
                  
            <line class="bond" id="mol1bnd4" x1="37.487" x2="27.439" y1="48.552" y2="54.349"/>
                  
            <g class="bond" id="mol1bnd5">
                        
                <line x1="27.439" x2="14.239" y1="54.349" y2="46.733"/>
                        
                <line x1="25.001" x2="14.239" y1="55.757" y2="49.548"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd6" x1="14.239" x2="1.038" y1="46.733" y2="54.349"/>
                  
            <g class="bond" id="mol1bnd7">
                        
                <line x1="1.038" x2="1.038" y1="54.349" y2="69.58"/>
                        
                <line x1="3.477" x2="3.477" y1="55.757" y2="68.172"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd8" x1="1.038" x2="14.239" y1="69.58" y2="77.196"/>
                  
            <g class="bond" id="mol1bnd9">
                        
                <line x1="14.239" x2="27.439" y1="77.196" y2="69.58"/>
                        
                <line x1="14.239" x2="25.001" y1="74.381" y2="68.172"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd10" x1="27.439" x2="27.439" y1="54.349" y2="69.58"/>
                  
            <line class="bond" id="mol1bnd11" x1="27.439" x2="37.928" y1="69.58" y2="75.631"/>
                  
            <line class="bond" id="mol1bnd12" x1="43.337" x2="53.841" y1="75.64" y2="69.58"/>
                  
            <g class="bond" id="mol1bnd13">
                        
                <line x1="53.841" x2="67.041" y1="69.58" y2="77.196"/>
                        
                <line x1="56.279" x2="67.041" y1="68.172" y2="74.381"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd14" x1="67.041" x2="80.242" y1="77.196" y2="69.58"/>
                  
            <g class="bond" id="mol1bnd15">
                        
                <line x1="80.242" x2="80.242" y1="69.58" y2="54.349"/>
                        
                <line x1="77.804" x2="77.804" y1="68.172" y2="55.757"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd16" x1="80.242" x2="67.041" y1="54.349" y2="46.733"/>
                  
            <g class="bond" id="mol1bnd17">
                        
                <line x1="67.041" x2="53.841" y1="46.733" y2="54.349"/>
                        
                <line x1="67.041" x2="56.279" y1="49.548" y2="55.757"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd18" x1="53.841" x2="53.841" y1="69.58" y2="54.349"/>
                  
            <line class="bond" id="mol1bnd19" x1="43.794" x2="53.841" y1="48.552" y2="54.349"/>
                  
            <line class="bond" id="mol1bnd20" x1="53.831" x2="53.831" y1="23.885" y2="12.504"/>
                  
            <line class="bond" id="mol1bnd21" x1="56.984" x2="67.022" y1="6.833" y2="1.038"/>
                  
            <line class="bond" id="mol1bnd22" x1="50.678" x2="40.64" y1="6.833" y2="1.038"/>
                  
            <path class="atom" d="M42.581 49.183h-.72l-2.62 -4.066h-.03q.012 .238 .03 .595q.024 .357 .024 .732v2.739h-.566v-4.9h.715l2.607 4.054h.03q-.006 -.107 -.018 -.327q-.012 -.221 -.024 -.477q-.006 -.261 -.006 -.482v-2.768h.578v4.9z" id="mol1atm4" stroke="none"/>
                  
            <path class="atom" d="M42.185 78.333q-.0 .649 -.476 1.018q-.471 .363 -1.268 .363q-.417 .0 -.768 -.065q-.346 -.06 -.578 -.173v-.589q.244 .113 .608 .202q.369 .089 .762 .089q.547 .0 .827 -.214q.28 -.214 .28 -.578q-.0 -.238 -.107 -.398q-.102 -.167 -.352 -.31q-.25 -.143 -.696 -.298q-.625 -.226 -.947 -.553q-.315 -.334 -.315 -.899q-.0 -.393 .196 -.667q.203 -.28 .554 -.429q.357 -.154 .815 -.154q.405 -.0 .739 .077q.339 .072 .613 .197l-.197 .529q-.25 -.113 -.547 -.184q-.298 -.078 -.625 -.078q-.459 .0 -.691 .197q-.232 .196 -.232 .518q-.0 .244 .101 .411q.107 .166 .339 .297q.233 .125 .631 .28q.429 .155 .727 .339q.297 .179 .452 .435q.155 .25 .155 .637z" fill="#C6C62C" id="mol1atm11" stroke="none"/>
                  
            <path class="atom" d="M55.772 11.104h-.721l-2.619 -4.066h-.03q.012 .238 .03 .595q.024 .357 .024 .732v2.739h-.566v-4.9h.715l2.607 4.054h.03q-.006 -.107 -.018 -.327q-.012 -.22 -.024 -.476q-.006 -.262 -.006 -.483v-2.768h.578v4.9z" id="mol1atm18" stroke="none"/>
                
            <line class="hi" id="mol1bnd3" stroke="#3050F8" x1="40.64" x2="40.64" y1="42.883" y2="37.192"/>
            <line class="hi" id="mol1bnd4" stroke="#3050F8" x1="37.487" x2="32.463" y1="48.552" y2="51.4505"/>
            <line class="hi" id="mol1bnd11" stroke="#C6C62C" x1="37.928" x2="32.683499999999995" y1="75.631" y2="72.6055"/>
            <line class="hi" id="mol1bnd12" stroke="#C6C62C" x1="43.337" x2="48.589" y1="75.64" y2="72.61"/>
            <line class="hi" id="mol1bnd19" stroke="#3050F8" x1="43.794" x2="48.817499999999995" y1="48.552" y2="51.4505"/>
            <line class="hi" id="mol1bnd20" stroke="#3050F8" x1="53.831" x2="53.831" y1="12.504" y2="18.1945"/>
            <line class="hi" id="mol1bnd21" stroke="#3050F8" x1="56.984" x2="62.003" y1="6.833" y2="3.9355"/>
            <line class="hi" id="mol1bnd22" stroke="#3050F8" x1="50.678" x2="45.659" y1="6.833" y2="3.9355"/>
        </g>
          
    </g>
    
</svg>
","Therapeutic Uses":"Anti-Allergic Agents; Antiemetics; Antipruritics; Histamine H1 Antagonists; Sedatives, Nonbarbiturate","Title":"Promethazine","UNII":"FF28EJQ494","Wikidata":"Q422970","Wikipedia":"Promethazine","XLogP":4.8}