{"ATC Code":"N - Nervous system","Abbreviation":"","Aliases":["Pramiracetam","Pramiracetamum","Pramiracetam hydrate","1-Pyrrolidineacetamide, N-(2-(bis(1-methylethyl)amino)ethyl)-2-oxo-","Pramistar","Pramiracetam","N-(2-(diisopropylamino)ethyl)-2-(2-oxopyrrolidin-1-yl)acetamide","N-[2-[bis(1-methylethyl)amino]ethyl]-2-oxo-1-pyrrolidineacetamide","4449F8I3LE","CI-879 FREE BASE"],"CAS":"68497-62-1","ChEBI":"CHEBI:135110","ChEMBL":"CHEMBL159776","ChemicalClasses":["racetam"],"Chirality":"achiral","DrugClasses":[],"European Community (EC) Number":"806-175-7","IUPACName":"N-[2-[di(propan-2-yl)amino]ethyl]-2-(2-oxopyrrolidin-1-yl)acetamide","InChI":"InChI=1S/C14H27N3O2/c1-11(2)17(12(3)4)9-7-15-13(18)10-16-8-5-6-14(16)19/h11-12H,5-10H2,1-4H3,(H,15,18)","InChIKey":"ZULJGOSFKWFVRX-UHFFFAOYSA-N","MolecularFormula":"C\u003csub\u003e14\u003c/sub\u003eH\u003csub\u003e27\u003c/sub\u003eN\u003csub\u003e3\u003c/sub\u003eO\u003csub\u003e2\u003c/sub\u003e","MolecularWeight":"269.38 g/mol","PubChemId":51712,"Record Description":["Pramiracetam is an organonitrogen compound and an organooxygen compound. It is functionally related to an alpha-amino acid.","Pramiracetam has been previously approved in some eastern European countries under the brand names Pramistar, Neupramir, and Remen. It was also previously approved in the United States with orphan drug designation. Pramiracetam has been studied for the use in Alzheimer's disease and as an adjunct treatment to restore cognitive functioning post-electroconvulsive therapy in severe depression.","PRAMIRACETAM is a small molecule drug with a maximum clinical trial phase of II and has 1 investigational indication.","Pramiracetam is an organonitrogen compound and an organooxygen compound. It is functionally related to an alpha-amino acid."],"References":[{"name":"Wikipedia","url":"https://en.wikipedia.org/wiki/Pramiracetam"},{"name":"Wikidata","url":"https://www.wikidata.org/wiki/Q415746"},{"name":"DrugBank","url":"https://go.drugbank.com/drugs/DB13247"},{"name":"PubChem","url":"https://pubchem.ncbi.nlm.nih.gov/compound/51712"},{"name":"ChemSpider","url":"https://www.chemspider.com/Chemical-Structure.46801.html"},{"name":"ChEMBL","url":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL159776"},{"name":"ChEBI","url":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:135110"},{"name":"Common Chemistry","url":"https://commonchemistry.cas.org/detail?cas_rn=68497-62-1"},{"name":"KEGG","url":"https://www.kegg.jp/entry/D08405"},{"name":"UNII","url":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/4449F8I3LE"},{"name":"EPA DSSTox","url":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID60218604"}],"SMILES":"CC(C)N(CCNC(=O)CN1CCCC1=O)C(C)C","Salts":["hydrochloride","sulfate"],"StructureBase64":"<svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" height="116.949mm" version="1.2" viewBox="0 0 96.648 116.949" width="96.648mm">
      
    <desc>Generated by the Chemistry Development Kit (http://github.com/cdk)</desc>
      
    <g fill="#3050F8" stroke="#000000" stroke-linecap="round" stroke-linejoin="round" stroke-width=".7">
            
        <rect fill="#FFFFFF" height="117.0" stroke="none" width="97.0" x=".0" y=".0"/>
            
        <g class="mol" id="mol1">
                  
            <line class="bond" id="mol1bnd1" x1="14.236" x2="27.435" y1="115.91" y2="108.29"/>
                  
            <line class="bond" id="mol1bnd2" x1="27.435" x2="40.633" y1="108.29" y2="115.91"/>
                  
            <line class="bond" id="mol1bnd3" x1="27.435" x2="27.435" y1="108.29" y2="96.9"/>
                  
            <line class="bond" id="mol1bnd4" x1="30.588" x2="40.633" y1="91.23" y2="85.43"/>
                  
            <line class="bond" id="mol1bnd5" x1="40.633" x2="40.633" y1="85.43" y2="70.19"/>
                  
            <line class="bond" id="mol1bnd6" x1="40.633" x2="50.678" y1="70.19" y2="64.391"/>
                  
            <line class="bond" id="mol1bnd7" x1="53.831" x2="53.831" y1="58.721" y2="47.33"/>
                  
            <g class="bond" id="mol1bnd8">
                        
                <line x1="53.831" x2="43.299" y1="48.738" y2="42.658"/>
                        
                <line x1="55.05" x2="44.518" y1="46.627" y2="40.546"/>
                      
                <line class="hi" stroke="#FF0D0D" x1="43.299" x2="48.565" y1="42.658" y2="45.698"/>
                <line class="hi" stroke="#FF0D0D" x1="44.518" x2="49.784" y1="40.546" y2="43.5865"/>
            </g>
                  
            <line class="bond" id="mol1bnd9" x1="53.831" x2="67.029" y1="47.33" y2="39.71"/>
                  
            <line class="bond" id="mol1bnd10" x1="67.029" x2="67.029" y1="39.71" y2="28.32"/>
                  
            <line class="bond" id="mol1bnd11" x1="63.961" x2="54.736" y1="22.213" y2="15.428"/>
                  
            <line class="bond" id="mol1bnd12" x1="54.736" x2="59.409" y1="15.428" y2="1.001"/>
                  
            <line class="bond" id="mol1bnd13" x1="59.409" x2="74.649" y1="1.001" y2="1.001"/>
                  
            <line class="bond" id="mol1bnd14" x1="74.649" x2="79.323" y1="1.001" y2="15.428"/>
                  
            <line class="bond" id="mol1bnd15" x1="70.098" x2="79.323" y1="22.213" y2="15.428"/>
                  
            <g class="bond" id="mol1bnd16">
                        
                <line x1="78.86" x2="90.611" y1="13.998" y2="17.784"/>
                        
                <line x1="78.112" x2="89.863" y1="16.319" y2="20.105"/>
                      
                <line class="hi" stroke="#FF0D0D" x1="90.611" x2="84.7355" y1="17.784" y2="15.890999999999998"/>
                <line class="hi" stroke="#FF0D0D" x1="89.863" x2="83.9875" y1="20.105" y2="18.212"/>
            </g>
                  
            <line class="bond" id="mol1bnd17" x1="24.281" x2="14.236" y1="91.23" y2="85.43"/>
                  
            <line class="bond" id="mol1bnd18" x1="14.236" x2="1.038" y1="85.43" y2="93.05"/>
                  
            <line class="bond" id="mol1bnd19" x1="14.236" x2="14.236" y1="85.43" y2="70.19"/>
                  
            <path class="atom" d="M29.375 95.5h-.72l-2.619 -4.066h-.03q.012 .238 .03 .596q.023 .357 .023 .732v2.738h-.565v-4.899h.714l2.608 4.054h.03q-.006 -.107 -.018 -.328q-.012 -.22 -.024 -.476q-.006 -.262 -.006 -.482v-2.768h.577v4.899z" id="mol1atm4" stroke="none"/>
                  
            <g class="atom" id="mol1atm7">
                        
                <path d="M55.772 65.02h-.721l-2.619 -4.066h-.03q.012 .238 .03 .596q.024 .357 .024 .732v2.738h-.566v-4.899h.715l2.607 4.054h.03q-.006 -.107 -.018 -.328q-.012 -.22 -.024 -.476q-.006 -.262 -.006 -.482v-2.768h.578v4.899z" stroke="none"/>
                        
                <path d="M60.078 65.02h-.619v-2.286h-2.512v2.286h-.614v-4.899h.614v2.071h2.512v-2.071h.619v4.899z" stroke="none"/>
                      
            </g>
                  
            <path class="atom" d="M42.892 39.708q.0 .756 -.256 1.327q-.256 .566 -.756 .881q-.5 .316 -1.244 .316q-.756 -.0 -1.262 -.316q-.506 -.315 -.756 -.887q-.244 -.571 -.244 -1.333q-.0 -.75 .244 -1.31q.25 -.566 .756 -.881q.506 -.316 1.274 -.316q.732 .0 1.232 .316q.5 .309 .756 .875q.256 .566 .256 1.328zM39.028 39.708q.0 .922 .387 1.458q.393 .53 1.221 .53q.839 -.0 1.22 -.53q.387 -.536 .387 -1.458q.0 -.929 -.387 -1.453q-.381 -.524 -1.208 -.524q-.834 .0 -1.227 .524q-.393 .524 -.393 1.453z" fill="#FF0D0D" id="mol1atm9" stroke="none"/>
                  
            <path class="atom" d="M68.97 26.92h-.72l-2.62 -4.066h-.029q.011 .238 .029 .596q.024 .357 .024 .732v2.738h-.565v-4.899h.714l2.607 4.054h.03q-.006 -.107 -.018 -.328q-.012 -.22 -.023 -.476q-.006 -.262 -.006 -.482v-2.768h.577v4.899z" id="mol1atm11" stroke="none"/>
                  
            <path class="atom" d="M96.088 20.098q-.0 .756 -.256 1.328q-.256 .566 -.756 .881q-.5 .316 -1.244 .316q-.756 -.0 -1.262 -.316q-.506 -.315 -.756 -.887q-.245 -.571 -.245 -1.333q.0 -.751 .245 -1.31q.25 -.566 .756 -.881q.506 -.316 1.274 -.316q.732 .0 1.232 .316q.5 .309 .756 .875q.256 .565 .256 1.327zM92.224 20.098q.0 .923 .387 1.459q.393 .53 1.221 .53q.839 -.0 1.22 -.53q.387 -.536 .387 -1.459q.0 -.928 -.387 -1.452q-.381 -.524 -1.208 -.524q-.834 -.0 -1.227 .524q-.393 .524 -.393 1.452z" fill="#FF0D0D" id="mol1atm16" stroke="none"/>
                
            <line class="hi" id="mol1bnd3" stroke="#3050F8" x1="27.435" x2="27.435" y1="96.9" y2="102.595"/>
            <line class="hi" id="mol1bnd4" stroke="#3050F8" x1="30.588" x2="35.6105" y1="91.23" y2="88.33000000000001"/>
            <line class="hi" id="mol1bnd6" stroke="#3050F8" x1="50.678" x2="45.6555" y1="64.391" y2="67.29050000000001"/>
            <line class="hi" id="mol1bnd7" stroke="#3050F8" x1="53.831" x2="53.831" y1="58.721" y2="53.025499999999994"/>
            <line class="hi" id="mol1bnd10" stroke="#3050F8" x1="67.029" x2="67.029" y1="28.32" y2="34.015"/>
            <line class="hi" id="mol1bnd11" stroke="#3050F8" x1="63.961" x2="59.3485" y1="22.213" y2="18.820500000000003"/>
            <line class="hi" id="mol1bnd15" stroke="#3050F8" x1="70.098" x2="74.7105" y1="22.213" y2="18.820500000000003"/>
            <line class="hi" id="mol1bnd17" stroke="#3050F8" x1="24.281" x2="19.258499999999998" y1="91.23" y2="88.33000000000001"/>
        </g>
          
    </g>
    
</svg>
","Title":"Pramiracetam","UNII":"4449F8I3LE","Wikidata":"Q415746","XLogP":0.8}