{"ATC Code":"N - Nervous system","Abbreviation":"","Aliases":["Domar","Pinazepamum","7-Chloro-1-propargyl-5-phenyl-2H-1,4-benzodiazepin-2-one","7-Chloro-1,3-dihydro-5-phenyl-1-(2-propynyl)-2H-1,4-benzodiazepin-2-one","7-chloro-5-phenyl-1-(prop-2-yn-1-yl)-2,3-dihydro-1H-1,4-benzodiazepin-2-one","propazepam","N05BA14","7-chloro-5-phenyl-1-propargyl-1,4-benzodiazepin-2-one","257-934-9","ZAMI 905","Duna","Z-905","2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-phenyl-1-(2-propynyl)-","7-Chloro-2,3-dihydro-5-phenyl-1-propargyl-1H-1,4-benzodiazepin-2-one","2H-1,4-benzodiazepin-2-one, 1,3-dihydro-7-chloro-5-phenyl-1-(2-propynyl)-","DB13335","D07314","Q7194856","7-Chloro-5-phenyl-1-prop-2-ynyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one","7-Chloro-5-phenyl-1-(2-propynyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one #","7-chloro-5-phenyl-1-prop-2-yn-1-yl-1,3-dihydro-2H-1,4-benzodiazepin-2-one"],"CAS":"52463-83-9","ChEBI":"CHEBI:135315","ChEMBL":"CHEMBL1213352","ChemicalClasses":["benzodiazepine"],"Chirality":"achiral","DEA no":2883,"EINECS":"257-934-9","Erowid Experience Reports":null,"Esters":[],"European Community (EC) Number":"257-934-9","Formating":[],"HMDB ID":"HMDB0041988","HeavyAtomCount":22,"IUPACName":"7-chloro-5-phenyl-1-prop-2-ynyl-3H-1,4-benzodiazepin-2-one","InChI":"InChI=1S/C18H13ClN2O/c1-2-10-21-16-9-8-14(19)11-15(16)18(20-12-17(21)22)13-6-4-3-5-7-13/h1,3-9,11H,10,12H2","InChIKey":"MFZOSKPPVCIFMT-UHFFFAOYSA-N","MeSH Pharmacological Classification":"Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here. (See all compounds classified as Anti-Anxiety Agents.)","Melting Point":"141 °C","MolecularFormula":"C\u003csub\u003e18\u003c/sub\u003eH\u003csub\u003e13\u003c/sub\u003eClN\u003csub\u003e2\u003c/sub\u003eO","MolecularWeight":"308.8 g/mol","Physical Description":"Solid","PubChemId":40391,"RefCount":3,"RefCur":"","References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Pinazepam","Name":"Pinazepam","Sub":false}]},{"Name":"DrugBank","Urls":[{"Link":"https://go.drugbank.com/drugs/DB13335","Name":"Pinazepam","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/40391","Name":"Pinazepam","Sub":false}]},{"Name":"ChEMBL","Urls":[{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1213352","Name":"Pinazepam","Sub":false}]},{"Name":"ChEBI","Urls":[{"Link":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:135315","Name":"Pinazepam","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=52463-83-9","Name":"Pinazepam","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0041988","Name":"Pinazepam","Sub":false}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/D07314","Name":"Pinazepam","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/5286RBZ882","Name":"Pinazepam","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID3023475","Name":"Pinazepam","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 40391, Pinazepam. Accessed July 20, 2025. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/40391\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/40391\u003c/a\u003e","U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Pinazepam. UNII: 5286RBZ882. Global Substance Registration System. Accessed July 20, 2025. \u003ca href=https://gsrs.ncats.nih.gov/ginas/app/beta/substances/5286RBZ882\u003ehttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/5286RBZ882\u003c/a\u003e"],"SMILES":"C#CCN1C(=O)CN=C(C2=C1C=CC(=C2)Cl)C3=CC=CC=C3","SaltData":[],"Salts":[],"StereoisomerData":[],"Stereoisomers":[],"Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 84.043 118.398\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#3050f8\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h85v119H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M75.828 2.843 64.652 13.204M77.486 4.631 66.31 14.992M74.17 1.055 62.994 11.416\"/\u003e\u003c/g\u003e\u003cpath d=\"M64.652 13.204 53.476 23.566M53.476 23.566l2.517 11.044M60.166 39.195l11.529 2.684\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m70.379 41.573 7.42-9.263M72.282 43.097l7.42-9.262\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"m77.799 32.31-3.71 4.632M79.702 33.835l-3.71 4.631\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath d=\"m71.695 41.879 6.604 13.716M78.299 55.595 73.482 65.6\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m56.862 72.766 11.529-2.685M57.464 70.122l10.374-2.416\"/\u003e\u003cpath stroke=\"#3050f8\" d=\"m68.391 70.081-5.764 1.343M67.838 67.706l-5.187 1.208\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath d=\"m56.862 72.766-11.887-9.551\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M44.975 63.215v-15.24M42.536 61.807V49.384\"/\u003e\u003c/g\u003e\u003cpath d=\"m53.83 40.861-8.855 7.114M44.975 47.975l-13.208-7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m31.767 40.355-13.208 7.62M31.767 43.171l-10.77 6.213\"/\u003e\u003c/g\u003e\u003cpath d=\"M18.559 47.975v15.24\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m18.559 63.215 13.208 7.62M20.997 61.807l10.77 6.213\"/\u003e\u003c/g\u003e\u003cpath d=\"m44.975 63.215-13.208 7.62M18.559 63.215 6.875 69.964M56.862 72.766l-3.386 14.859\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M64.662 97.989 53.476 87.625M61.971 98.82l-9.12-8.45\"/\u003e\u003c/g\u003e\u003cpath d=\"m64.662 97.989-3.386 14.859\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m46.705 117.343 14.571-4.495M47.331 114.599l11.88-3.666\"/\u003e\u003c/g\u003e\u003cpath d=\"M46.705 117.343 35.52 106.98\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M38.906 92.121 35.52 106.98M40.97 94.035l-2.76 12.113\"/\u003e\u003c/g\u003e\u003cpath d=\"m53.476 87.625-14.57 4.496\" class=\"bond\"/\u003e\u003cpath stroke=\"none\" d=\"M58.802 40.875h-.72l-2.619-4.066h-.03l.03.595q.024.357.024.732v2.739h-.566v-4.9h.714l2.608 4.054h.03l-.018-.327-.024-.476q-.006-.262-.006-.482v-2.769h.577z\" class=\"atom\"/\u003e\u003cpath fill=\"#ff0d0d\" stroke=\"none\" d=\"M83.483 29.983q0 .756-.256 1.327-.256.566-.756.881t-1.244.316q-.756 0-1.262-.316-.506-.315-.756-.887-.244-.571-.244-1.333 0-.75.244-1.31.25-.566.756-.881t1.274-.316q.732 0 1.232.316.5.31.756.875.256.566.256 1.328m-3.863 0q0 .922.387 1.458.392.53 1.22.53.839 0 1.22-.53.387-.536.387-1.458 0-.929-.387-1.453-.381-.524-1.208-.524-.834 0-1.226.524-.393.524-.393 1.453\" class=\"atom\"/\u003e\u003cpath stroke=\"none\" d=\"M73.636 71.761h-.72l-2.62-4.066h-.029l.029.595q.024.358.024.733v2.738h-.565v-4.899h.714l2.607 4.054h.03l-.018-.328q-.012-.22-.023-.476-.006-.262-.006-.482v-2.768h.577z\" class=\"atom\"/\u003e\u003cpath fill=\"#1ff01f\" stroke=\"none\" d=\"M2.906 69.022q-.786 0-1.239.53-.452.524-.452 1.446 0 .911.417 1.447.422.53 1.268.53.321 0 .607-.054.292-.059.565-.143v.536q-.273.101-.565.149-.292.053-.697.053-.744 0-1.25-.309-.5-.31-.75-.875-.25-.572-.25-1.34 0-.744.268-1.309.274-.566.804-.881.529-.322 1.279-.322.78 0 1.352.286l-.244.524q-.226-.101-.506-.185-.274-.083-.607-.083m2.756 4.423h-.601V68.23h.601z\" class=\"atom\"/\u003e\u003cpath stroke=\"#3050f8\" d=\"m55.993 34.61-1.259-5.522M60.166 39.195l5.764 1.342M73.482 65.6l2.409-5.003M53.83 40.861l-4.427 3.557\" class=\"hi\"/\u003e\u003cpath stroke=\"#1ff01f\" d=\"m6.875 69.964 5.842-3.374\" class=\"hi\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Title":"Pinazepam","UNII":"5286RBZ882","Wikipedia":"Pinazepam","XLogP":3.1}