{"Abbreviation":"EGYT-475","Aliases":["Piberalina","Piberalinum","1-Benzyl-4-picolinoylpiperazine","Egyt 475","1-Benzyl-4-(2'-pyridinecarbonyl)piperazine","Piperazine, 1-(phenylmethyl)-4-(2-pyridinylcarbonyl)-","Trelibet","1-benzyl-4-(2'-pyridylcarbonyl)piperazine","EGYT-475","Q7190435","Z27763796"],"CAS":"39640-15-8","ChEBI":"CHEBI:135167","ChEMBL":"CHEMBL2105223","ChemicalClasses":["benzylpiperazine"],"Chirality":"achiral","Classes":["Stimulant"],"Erowid Experience Reports":null,"Esters":[],"Formating":[],"HMDB ID":"HMDB0256526","HeavyAtomCount":21,"IUPACName":"(4-benzylpiperazin-1-yl)-pyridin-2-ylmethanone","InChI":"InChI=1S/C17H19N3O/c21-17(16-8-4-5-9-18-16)20-12-10-19(11-13-20)14-15-6-2-1-3-7-15/h1-9H,10-14H2","InChIKey":"TZFUBYYADABEAV-UHFFFAOYSA-N","MolecularFormula":"C\u003csub\u003e17\u003c/sub\u003eH\u003csub\u003e19\u003c/sub\u003eN\u003csub\u003e3\u003c/sub\u003eO","MolecularWeight":"281.35 g/mol","PubChemId":65975,"RefCount":3,"RefCur":"","References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Piberaline","Name":"Piberaline","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/65975","Name":"Piberaline","Sub":false}]},{"Name":"ChEMBL","Urls":[{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2105223","Name":"Piberaline","Sub":false}]},{"Name":"ChEBI","Urls":[{"Link":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:135167","Name":"Piberaline","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=39640-15-8","Name":"Piberaline","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0256526","Name":"Piberaline","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/8M09P36809","Name":"Piberaline","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID40192751","Name":"Piberaline","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 65975, Piberaline. Accessed July 19, 2025. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/65975\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/65975\u003c/a\u003e","U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Piberaline. UNII: 8M09P36809. Global Substance Registration System. Accessed July 19, 2025. \u003ca href=https://gsrs.ncats.nih.gov/ginas/app/beta/substances/8M09P36809\u003ehttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/8M09P36809\u003c/a\u003e"],"SMILES":"C1CN(CCN1CC2=CC=CC=C2)C(=O)C3=CC=CC=N3","SaltData":[],"Salts":[],"StereoisomerData":[],"Stereoisomers":[],"Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 134.02 49.833\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#3050f8\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h135v50H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"m53.809 23.909 13.202 7.613M67.011 31.522l10.046-5.797M80.21 20.055l-.002-11.382M80.208 8.673 67.006 1.059M67.006 1.059 56.96 6.857M53.809 23.909l-.002-11.382M50.653 6.857 40.616 1.061M40.616 1.061 27.425 8.677\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M27.425 8.677 14.229 1.053M24.987 10.085 14.229 3.869\"/\u003e\u003c/g\u003e\u003cpath d=\"M14.229 1.053 1.038 8.669\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m1.038 8.669.005 15.24M3.477 10.076l.004 12.425\"/\u003e\u003c/g\u003e\u003cpath d=\"m1.043 23.909 13.196 7.624\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m14.239 31.533 13.191-7.616M14.239 28.717l10.752-6.207\"/\u003e\u003c/g\u003e\u003cpath d=\"m27.425 8.677.005 15.24M83.364 25.725l10.037 5.795\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M94.621 30.816v12.015M92.182 30.816v12.015\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"M94.621 42.831v-6.007M92.182 42.831v-6.007\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath d=\"m93.401 31.52 13.191-7.615\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m106.592 23.905 13.192 7.613M109.031 22.497l10.752 6.205\"/\u003e\u003c/g\u003e\u003cpath d=\"m119.784 31.518 13.195-7.626\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m132.979 23.892.002-15.24M130.541 22.485l.002-12.425\"/\u003e\u003c/g\u003e\u003cpath d=\"m132.981 8.652-13.192-7.614\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m119.789 1.038-10.041 5.804M119.79 3.854l-8.822 5.099\"/\u003e\u003cpath stroke=\"#3050f8\" d=\"m109.748 6.842 5.021-2.902M110.968 8.953l4.411-2.55\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath d=\"m106.592 23.905.002-11.391\" class=\"bond\"/\u003e\u003cpath stroke=\"none\" d=\"M82.151 26.354h-.72l-2.62-4.066h-.029l.029.596q.024.357.024.732v2.738h-.565v-4.899h.714l2.608 4.054h.029l-.018-.327-.023-.477q-.006-.262-.006-.482v-2.768h.577zM55.747 11.127h-.72l-2.619-4.066h-.03l.03.595q.023.357.023.733v2.738h-.565V6.228h.714l2.608 4.054h.03l-.018-.328-.024-.476q-.006-.262-.006-.482V6.228h.577z\" class=\"atom\"/\u003e\u003cpath fill=\"#ff0d0d\" stroke=\"none\" d=\"M95.661 46.749q0 .756-.256 1.327-.256.566-.756.882-.501.315-1.245.315-.756 0-1.262-.315-.506-.316-.756-.887-.244-.572-.244-1.334 0-.75.244-1.31.25-.565.756-.881.506-.315 1.274-.315.732 0 1.233.315.5.31.756.875.256.566.256 1.328m-3.864 0q0 .923.387 1.458.393.53 1.22.53.84 0 1.221-.53.387-.535.387-1.458 0-.929-.387-1.453-.381-.524-1.209-.524-.833 0-1.226.524t-.393 1.453\" class=\"atom\"/\u003e\u003cpath stroke=\"none\" d=\"M108.535 11.114h-.72l-2.619-4.066h-.03l.03.596q.024.357.024.732v2.738h-.566V6.215h.714l2.608 4.054h.03l-.018-.327-.024-.477q-.006-.262-.006-.482V6.215h.577z\" class=\"atom\"/\u003e\u003cpath stroke=\"#3050f8\" d=\"m77.057 25.725-5.023 2.898M80.21 20.055l-.001-5.691M56.96 6.857l5.023-2.899M53.807 12.527l.001 5.691M50.653 6.857l-5.018-2.898M83.364 25.725l5.018 2.898M106.594 12.514l-.001 5.695\" class=\"hi\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Subjective Effects":{"Cognitive Effects":["Analysis enhancement","Ego inflation","Focus enhancement","Increased music appreciation","Motivation enhancement","Thought acceleration","Wakefulness","Disinhibition","Suggestibility suppression","Cognitive euphoria","Compulsive redosing","Mania"],"Physical Effects":["Increased libido","Stamina enhancement","Stimulation","Appetite suppression","Dehydration","Dry mouth","Restless legs","Shakiness","Teeth grinding","Abnormal heartbeat","Increased blood pressure","Increased heart rate","Vasoconstriction"],"Visual Effects":[]},"Title":"Piberaline","UNII":"8M09P36809","Wikipedia":"Piberaline","XLogP":2}