{"Abbreviation":"PP","Aliases":["1-Phenylpiperazine","202-165-6","N-Phenylpiperazine","Piperazine, 1-phenyl-","1-Phenyl-piperazine","N-Phenyldiethylenediamine","4-phenylpiperazine","n-phenyl piperazine","1-Fenylpiperazin","N-phenylpiperazin","CCRIS 4334","Piperazine, 1-phenyl-, dihydrochloride","AI3-26332","phenyl piperazine","phenyl-piperazine","4-phenylpiperazin","N-phenylpiperizine","N-phenylpyperazine","1-Phenypiperazine","1-Phenylpiperazine; N-Phenylpiperazine; NPP; Phenylpiperazine; Levodropropizine Imp. B","4-phenylpiperizine","N-phenyl piperazin","N-phenyl-piperazine","1-phenyl piperazine","4-phenyl piperazine"],"CAS":"92-54-6","ChEMBL":"CHEMBL9434","ChemicalClasses":["phenylpiperazine"],"Chirality":"achiral","Classes":["Stimulant"],"EINECS":"202-165-6","Erowid Experience Reports":null,"Esters":[],"European Community (EC) Number":"202-165-6","Formating":[],"HMDB ID":"HMDB0243993","HeavyAtomCount":12,"IUPACName":"1-phenylpiperazine","InChI":"InChI=1S/C10H14N2/c1-2-4-10(5-3-1)12-8-6-11-7-9-12/h1-5,11H,6-9H2","InChIKey":"YZTJYBJCZXZGCT-UHFFFAOYSA-N","MeSH Pharmacological Classification":"Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma. (See all compounds classified as Adrenergic alpha-Antagonists.)","MolecularFormula":"C\u003csub\u003e10\u003c/sub\u003eH\u003csub\u003e14\u003c/sub\u003eN\u003csub\u003e2\u003c/sub\u003e","MolecularWeight":"162.23 g/mol","PubChemId":7096,"RefCount":3,"RefCur":"","References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Phenylpiperazine","Name":"Phenylpiperazine","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/7096","Name":"Phenylpiperazine","Sub":false}]},{"Name":"ChEMBL","Urls":[{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL9434","Name":"Phenylpiperazine","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=92-54-6","Name":"Phenylpiperazine","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0243993","Name":"Phenylpiperazine","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/J9225CBI7D","Name":"Phenylpiperazine","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID8057855","Name":"Phenylpiperazine","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 7096, Phenylpiperazine. Accessed July 19, 2025. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/7096\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/7096\u003c/a\u003e","U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Phenylpiperazine. UNII: J9225CBI7D. Global Substance Registration System. Accessed July 19, 2025. \u003ca href=https://gsrs.ncats.nih.gov/ginas/app/beta/substances/J9225CBI7D\u003ehttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/J9225CBI7D\u003c/a\u003e"],"SMILES":"C1CN(CCN1)C2=CC=CC=C2","SaltData":[],"Salts":[],"StereoisomerData":[],"Stereoisomers":[],"Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 73.804 55.404\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#3050f8\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h74v56H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"m67.002 23.902-13.19 7.616M53.812 31.518l-10.043-5.802M40.615 20.044l-.004-11.39M40.611 8.654l13.191-7.616M53.802 1.038l10.042 5.803M67.002 23.902l-.003-11.39M37.462 25.715 27.425 31.51\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m27.43 46.75-.005-15.24M24.991 45.342l-.004-12.425\"/\u003e\u003c/g\u003e\u003cpath d=\"m27.43 46.75-13.191 7.616\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m1.043 46.741 13.196 7.625M3.481 45.334l10.758 6.216\"/\u003e\u003c/g\u003e\u003cpath d=\"m1.043 46.741-.005-15.24\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M14.229 23.886 1.038 31.501M14.229 26.701 3.477 32.909\"/\u003e\u003c/g\u003e\u003cpath d=\"m27.425 31.51-13.196-7.624\" class=\"bond\"/\u003e\u003cpath stroke=\"none\" d=\"M42.556 26.344h-.72l-2.619-4.066h-.03l.03.595q.024.357.024.732v2.739h-.566v-4.9h.714l2.608 4.054h.03l-.018-.327-.024-.476q-.006-.262-.006-.483v-2.768h.577z\" class=\"atom\"/\u003e\u003cg stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M68.938 11.112h-.72l-2.619-4.066h-.03l.03.595q.023.358.023.733v2.738h-.565V6.213h.714l2.608 4.054h.029l-.017-.328-.024-.476q-.006-.262-.006-.482V6.213h.577zM73.244 11.112h-.619V8.826h-2.512v2.286H69.5V6.213h.613v2.071h2.512V6.213h.619z\"/\u003e\u003c/g\u003e\u003cpath stroke=\"#3050f8\" d=\"m43.769 25.716 5.021 2.901M40.615 20.044l-.002-5.695M63.844 6.841 58.823 3.94M66.999 12.512 67 18.207M66.999 12.512 67 18.207M37.462 25.715l-5.018 2.898\" class=\"hi\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Subjective Effects":{"Cognitive Effects":["Analysis enhancement","Ego inflation","Focus enhancement","Increased music appreciation","Motivation enhancement","Thought acceleration","Wakefulness","Disinhibition","Suggestibility suppression","Cognitive euphoria","Compulsive redosing","Mania"],"Physical Effects":["Increased libido","Stamina enhancement","Stimulation","Appetite suppression","Dehydration","Dry mouth","Restless legs","Shakiness","Teeth grinding","Abnormal heartbeat","Increased blood pressure","Increased heart rate","Vasoconstriction"],"Visual Effects":[]},"Title":"Phenylpiperazine","UNII":"J9225CBI7D","Wikipedia":"Phenylpiperazine","XLogP":1.1}