{"Aliases":["DN-2327","A-77000","DN2327","2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(((1,4-dioxa-8-azaspiro(4.5)dec-8-yl)carbonyl)methyl)-1-isoindolinone","8-((2-(7-Chloro-1,8-naphthyridin-2-yl)-3-oxo-1-isoindolinyl)acetyl)-1,4-dioxa-8-azaspiro(4.5)decane","A77000","pazinaclonum","Dtxcid80817375","2-(7-chloro-1,8-naphthyridin-2-yl)-3-((1,4-dioxa-8-azaspiro(4.5)dec-8-yl)carbonylmethyl)isoindolin-1-one","pazinaclona","DN 2327","R-(-)-Pazinaclone","1,4-Dioxa-8-azaspiro[4.5]decane,8-[[2-(7-chloro-1,8-naphthyridin-2-yl)-2,3-dihydro-3-oxo-1H-isoindol-1-yl]acetyl]-","Pazinaclone, (R)-","1H-Isoindol-1-one, 2-(7-chloro-1,8-naphthyridin-2-yl)-3-[2-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)-2-oxoethyl]-2,3-dihydro-;1H-Isoindol-1-one, 2-(7-chloro-1,8-naphthyridin-2-yl)-3-[2-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)-2-oxoethyl]-2,3-dihydro-","2RL7K6WX26","147724-30-9","A 77000","Oprea1_524484","Schembl120974","Schembl29556471","1,4-Dioxa-8-azaspiro(4.5)decane, 8-((2-(7-chloro-1,8-naphthyridin-2-yl)-2,3-dihydro-3-oxo-1H-isoindol-1-yl)acetyl)-, (R)-","Akos015913910","1,4-Dioxa-8-azaspiro(4.5)decane, 8-((2-(7-chloro-1,8-naphthyridin-2-yl)-2,3-dihydro-3-oxo-1H-isoindol-1-yl)acetyl)-","1,4-Dioxa-8-azaspiro(4.5)decane, 8-((2-(7-chloro-1,8-naphthyridin-2-yl)-2,3-dihydro-3-oxo-1H-isoindol-1-yl)acetyl)-, (+-)-","2-(7-chloro-1,8-naphthyridin-2-yl)-3-(2-oxo-2-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)ethyl)isoindolin-1-one","TS-08602","DB-040434","NS00121088","D05378","1,4-Dioxa-8-azaspiro(4.5)decane, 8-((2-(7-chloro-1,8-naphthyridin-2-yl)-2,3-dihydro-3-oxo-1h-isoindol-1-yl)acetyl)-","1H-isoindol-1-one, 2-(7-chloro-1,8-naphthyridin-2-yl)-3-(2-(1,4-dioxa-8-azaspiro(4.5)dec-8-yl)-2-oxoethyl)-2,3-dihydro-","2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)carbonylmethylisoindolin-1-one","2-(7-Chloro-1,8-naphthyridin-2-yl)-3-[2-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-2-oxoethyl]-2,3-dihydro-1H-isoindol-1-one"],"CAS":"103255-66-9","ChemicalClasses":["cyclopyrrolone"],"Chirality":"racemic","DTXSID":"70869388","Druglikeness":{"Lipinski":{"Passes":true,"Violations":0}},"EliminationHalfLife":"","Erowid Experience Reports":[],"Esters":[],"Formating":[],"HMDB ID":"HMDB0243694","HeavyAtomCount":34,"IUPACName":"2-(7-chloro-1,8-naphthyridin-2-yl)-3-[2-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-2-oxoethyl]-3H-isoindol-1-one","InChI":"InChI=1S/C25H23ClN4O4/c26-20-7-5-16-6-8-21(28-23(16)27-20)30-19(17-3-1-2-4-18(17)24(30)32)15-22(31)29-11-9-25(10-12-29)33-13-14-34-25/h1-8,19H,9-15H2","InChIKey":"DPGKFACWOCLTCA-UHFFFAOYSA-N","MeSH Headers":[{"Id":"M0167815","Link":"https://id.nlm.nih.gov/mesh/M0167815.html","Name":"pazinaclone","Ref":19},{"Id":"DescTree","Link":"https://www.nlm.nih.gov/mesh/meshhome.html","Name":"MeSH Tree","Ref":21},{"Id":"PubMed from MeSH","Link":"https://www.nlm.nih.gov/mesh/meshhome.html","Name":null,"Ref":31}],"MolecularFormula":"C\u003csub\u003e25\u003c/sub\u003eH\u003csub\u003e23\u003c/sub\u003eClN\u003csub\u003e4\u003c/sub\u003eO\u003csub\u003e4\u003c/sub\u003e","MolecularWeight":"478.9 g/mol","Opticalactivity":"( + / - )","Passes":true,"PubChemId":59743,"PubChemTitle":"Pazinaclone","Records":{"UNII":{"Impurities":[]}},"RefChem":"928641","RefCount":3,"RefCur":"","References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Pazinaclone","Name":"Pazinaclone","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q7157014","Name":"Pazinaclone","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/59743","Name":"Pazinaclone","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=103255-66-9","Name":"Pazinaclone","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0243694","Name":"Pazinaclone","Sub":false}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/D05378","Name":"Pazinaclone","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/MHK03047IJ","Name":"Pazinaclone","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID70869388","Name":"Pazinaclone","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 59743, Pazinaclone. Accessed June 12, 2026. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/59743\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/59743\u003c/a\u003e","U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Pazinaclone. UNII: MHK03047IJ. Global Substance Registration System. Accessed June 12, 2026. \u003ca href=https://gsrs.ncats.nih.gov/ginas/app/beta/substances/MHK03047IJ\u003ehttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/MHK03047IJ\u003c/a\u003e"],"SMILES":"C1CN(CCC12OCCO2)C(=O)CC3C4=CC=CC=C4C(=O)N3C5=NC6=C(C=C5)C=CC(=N6)Cl","SaltData":[],"Salts":[],"Scheduling":[],"StereoisomerData":[{"ChemicalClasses":["cyclopyrrolone"],"SMILES":"O=C(C[C@@H]1C2=CC=CC=C2C(=O)N1C1=CC=C2C=CC(Cl)=NC2=N1)N1CCC2(CC1)OCCO2","Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 123.791 150.247\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#ff0d0d\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".8\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h124v151H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cg 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