{"Actives":["Bupropion","Hydroxybupropion","Threohydrobupropion","Erythrohydrobupropion"],"Aliases":["Chembl578612","N-methyl-bupropion","Schembl770030","Schembl29465709","Bdbm50302919","2-(N-Methyl-N-tert-butylamino)-3''-chloropropiophenone"],"ChemicalClasses":["cathinone"],"Chirality":"racemic","Classes":["Stimulant"],"Erowid Experience Reports":[],"Esters":[],"Formating":[],"HeavyAtomCount":17,"IUPACName":"2-[tert-butyl(methyl)amino]-1-(3-chlorophenyl)propan-1-one","InChI":"InChI=1S/C14H20ClNO/c1-10(16(5)14(2,3)4)13(17)11-7-6-8-12(15)9-11/h6-10H,1-5H3","InChIKey":"BJLKZFUZNNATGZ-UHFFFAOYSA-N","MeSH Headers":[],"MolecularFormula":"C\u003csub\u003e14\u003c/sub\u003eH\u003csub\u003e20\u003c/sub\u003eClNO","MolecularWeight":"253.77 g/mol","PD":"PD089650","PubChemId":20695745,"RefCount":2,"RefCur":"","References":[{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/20695745","Name":"N-Methylbupropion","Sub":false}]},{"Name":"Probes \u0026 Drugs","Urls":[{"Link":"https://www.probes-drugs.org/compound/PD089650","Name":"N-Methylbupropion","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 20695745, Chembl578612. Accessed May 14, 2026. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/20695745\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/20695745\u003c/a\u003e"],"SMILES":"CC(C(=O)C1=CC(=CC=C1)Cl)N(C)C(C)(C)C","SaltData":[],"Salts":[],"StereoisomerData":[{"ChemicalClasses":["cathinone"],"SMILES":"C[C@H](C(=O)C1=CC(Cl)=CC=C1)N(C)C(C)(C)C","Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 100.707 62.917\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#1ff01f\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h101v63H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M71.709 39.01h-.7M71.959 41.187h-1.2M72.209 43.364h-1.7M72.459 45.541h-2.2M72.709 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stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h101v63H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath stroke=\"none\" d=\"M71.709 39.01h-.7l-1.75 15.24h4.2z\" class=\"bond\"/\u003e\u003cpath d=\"m71.359 39.01-13.198-7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M56.941 32.094V20.071M59.38 32.094V20.071\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"M56.941 20.071v6.012M59.38 20.071v6.012\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath d=\"m58.161 31.39-13.199 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m44.962 39.01-13.203-7.628M42.524 40.418l-10.765-6.221\"/\u003e\u003c/g\u003e\u003cpath d=\"m31.759 31.382-13.198 7.62M18.561 39.002 6.875 32.257\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m18.561 39.002.005 15.248M21 40.409l.004 12.433\"/\u003e\u003c/g\u003e\u003cpath d=\"m18.566 54.25 13.203 7.629\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m31.769 61.879 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fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#1ff01f\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h101v63H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"M71.359 54.25V39.01M71.359 39.01l-13.198-7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M56.941 32.094V20.071M59.38 32.094V20.071\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"M56.941 20.071v6.012M59.38 20.071v6.012\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath d=\"m58.161 31.39-13.199 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m44.962 39.01-13.203-7.628M42.524 40.418l-10.765-6.221\"/\u003e\u003c/g\u003e\u003cpath d=\"m31.759 31.382-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m18.561 39.002.005 15.248M21 40.409l.004 12.433\"/\u003e\u003c/g\u003e\u003cpath 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suppression","Cognitive euphoria","Compulsive redosing","Mania"],"Physical Effects":["Increased libido","Stamina enhancement","Stimulation","Appetite suppression","Dehydration","Dry mouth","Restless legs","Shakiness","Teeth grinding","Abnormal heartbeat","Increased blood pressure","Increased heart rate","Vasoconstriction"],"Visual Effects":[]},"Title":"N-Methylbupropion","XLogP":3.7}