{"Abbreviation":"","Aliases":["1-Oxa-4-azacyclohexane","Diethylene oximide","Tetrahydro-1,4-oxazine","Diethylenimide oxide","Diethyleneimide oxide","Diethylene imidoxide","Drewamine","Tetrahydro-2H-1,4-oxazine","Tetrahydro-p-oxazine","p-Isoxazine, tetrahydro-","Tetrahydro-1,4-isoxazine","BASF 238","2H-1,4-Oxazine, tetrahydro-","4H-1,4-Oxazine, tetrahydro-","203-815-1","138048-80-3","C4H9NO","Tetrahydro-4H-1-4-oxazine","morpholin","Caswell No. 584","Cas-110-91-8","CCRIS 2482","Morpholine,reag","Tetrahydro-p-isoxazine","Morpholine, pract"],"Biological Half-Life":"After ip admin of 125 mg/kg (14)C-morpholine (50 uCi)/animal, the blood plasma half-lives in the rat, hamster, and guinea pig were 115, 120, and 300 min, respectively.","Boiling Point":"264 °","CAS":"110-91-8","ChEBI":"CHEBI:34856","ChEMBL":"CHEMBL276518","ChemicalClasses":["morpholine"],"Chirality":"achiral","Color/Form":"Colorless liquid","Decomposition":"When heated to decomposition it emits highly toxic fumes of /nitric oxide/.","Density":"1 at 68 °F (USCG, 1999) g/cm\u003csup\u003e3\u003c/sup\u003e","EINECS":"203-815-1","Erowid Experience Reports":null,"Esters":[],"European Community (EC) Number":"203-815-1","Flash Point":"100 °F (NTP, 1992)","Formating":[],"HMDB ID":"HMDB0031581","HeavyAtomCount":6,"IUPACName":"morpholine","InChI":"InChI=1S/C4H9NO/c1-3-6-4-2-5-1/h5H,1-4H2","InChIKey":"YNAVUWVOSKDBBP-UHFFFAOYSA-N","Melting Point":"23.2 °","MolecularFormula":"C\u003csub\u003e4\u003c/sub\u003eH\u003csub\u003e9\u003c/sub\u003eNO","MolecularWeight":"87.12 g/mol","Odor":"Characteristic amine","Physical Description":"Morpholine appears as a colorless liquid with a fishlike odor. Flash point 100 °F. Corrosive to tissue. Less dense than water and soluble in water. Vapors heavier than air. Used to make other chemicals, as a corrosion inhibitor, and in detergents.","PubChemId":8083,"RefCount":2,"RefCur":"","References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Morpholine","Name":"Morpholine","Sub":false}]},{"Name":"DrugBank","Urls":[{"Link":"https://go.drugbank.com/drugs/DB13669","Name":"Morpholine","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/8083","Name":"Morpholine","Sub":false}]},{"Name":"ChEMBL","Urls":[{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL276518","Name":"Morpholine","Sub":false}]},{"Name":"ChEBI","Urls":[{"Link":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:34856","Name":"Morpholine","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=110-91-8","Name":"Morpholine","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0031581","Name":"Morpholine","Sub":false}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/C14452","Name":"Morpholine","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/8B2ZCK305O","Name":"Morpholine","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID2025688","Name":"Morpholine","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 8083, Morpholine. Accessed July 21, 2025. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/8083\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/8083\u003c/a\u003e"],"Reported Fatal Dose":"4. 4 = very toxic: probable oral lethal dose (human) 50-500 mg/kg; between 1 teaspoon \u0026 1 ounce for 70 kg person (150 lb).","SMILES":"C1COCCN1","SaltData":[],"Salts":[],"Solubility":"Soluble (NTP, 1992)","StereoisomerData":[],"Stereoisomers":[],"Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 28.478 42.015\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#3050f8\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h29v43H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"M1.038 25.928V10.697M1.038 10.697l9.919-5.723M17.515 4.971l9.924 5.726M27.439 10.697v15.231M27.439 25.928l-10.047 5.797M1.038 25.928l10.047 5.797\" class=\"bond\"/\u003e\u003cpath fill=\"#ff0d0d\" stroke=\"none\" d=\"M16.498 3.078q0 .756-.256 1.328-.256.565-.756.881-.5.315-1.244.315-.756 0-1.262-.315-.506-.316-.756-.887-.244-.572-.244-1.334 0-.75.244-1.309.25-.566.756-.881T14.254.56q.732 0 1.232.316.5.309.756.875.256.565.256 1.327m-3.864 0q0 .923.387 1.459.393.53 1.221.53.839 0 1.22-.53.387-.536.387-1.459 0-.929-.387-1.452-.381-.524-1.208-.524-.834 0-1.227.524-.393.523-.393 1.452\" class=\"atom\"/\u003e\u003cg stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M16.18 35.994h-.721l-2.619-4.066h-.03l.03.595q.024.357.024.733v2.738h-.566v-4.899h.714l2.608 4.054h.03l-.018-.328-.024-.476q-.006-.262-.006-.482v-2.768h.578zM16.043 41.455h-.62v-2.286h-2.512v2.286h-.613v-4.899h.613v2.071h2.512v-2.071h.62z\"/\u003e\u003c/g\u003e\u003cpath stroke=\"#ff0d0d\" d=\"M10.957 4.974 5.998 7.835M17.515 4.971l4.962 2.863\" class=\"hi\"/\u003e\u003cpath stroke=\"#3050f8\" d=\"m17.392 31.725 5.024-2.898M11.085 31.725l-5.023-2.898\" class=\"hi\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Therapeutic Uses":"Morpholine has antibacterial and antimycotic properties, as has been demonstrated on pathogenic organisms.","Title":"Morpholine","UNII":"8B2ZCK305O","Wikipedia":"Morpholine","XLogP":-0.9,"pH":"Strong base"}