{"ATC Code":["N - Nervous system","N02 - Analgesics","N02A - Opioids","N02AA - Natural opium alkaloids","N02AA01","N02AA01","N02AA01","N02AA01 - Morphine","QN - Nervous system","QN02 - Analgesics","QN02A - Opioids","QN02AA - Natural opium alkaloids","QN02AA01 - Morphine"],"Absorption, Distribution and Excretion":"Morphine is absorbed in the alkaline environments of the upper intestine and rectal mucosa. The bioavailability of morphine is 80-100%. There is significant first-pass metabolism, therefore oral doses are 6 times larger than parenteral doses to achieve the same effect. Morphine reaches steady-state concentrations after 24-48 hours. Parenteral morphine has a Tmax of 15 minutes and oral morphine has a Tmax of 90 minutes, with a Cmax of 283nmol/L. The AUC of morphine is 225-290nmol\\*h/L.","Adverse Effects":"Skin Sensitizer - An agent that can induce an allergic reaction in the skin.","Aliases":["Morphia","Morphium","Morphina","Morphinum","Ospalivina","Morphin","Duromorph","Meconium","Morphinism","Nepenthe","Dulcontin","Roxanol","Morfina","Morpho","Statex SR","Anhydrous morphine","M-Eslon","Aguettant","Dinamorf","Dimorf","Morphine anhydrous","Morphine extended release","(5R,6S,9R,13S,14R)-4,5-Epoxy-N-methyl-7-morphinen-3,6-diol","IDS-NM-009","Chebi:17303","4,5α-Epoxy-17-methyl-7-morphinen-3,6α-diol","N02AA01","7,8-Didehydro-4,5-epoxy-17-methyl-morphinan-3,6-diol","(5α,6α)-17-methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol","9H-9,9c-Iminoethanophenanthro(4,5-bcd)furan-3,5-diol, 4a,5,7a,8-tetrahydro-12-methyl-","(7R,7as,12bs)-3-methyl-2,3,4,4a,7,7a-hexahydro-1h-4,12-methano[1]benzofuro[3,2-e]isoquinoline-7,9-diol","Chloride, Morphine","(5α,6α)-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol","morphine tincture","Contin, MS","(1S,5R,13R,14S,17R)-4-methyl-12-oxa-4-azapentacyclo(9.6.1.0^(1,13).0^(5,17).0^(7,18))octadeca-7(18),8,10,15-tetraene-10,14-diol","(1S,5R,13R,14S,17R)-4-methyl-12-oxa-4-azapentacyclo(9.6.1.0^(1,13).0^(5,17).0^(7,18))octadeca-7,9,11(18),15-tetraene-10,14-diol","(1S,5R,13R,14S,17R)-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10,15-tetraene-10,14-diol","(1S,5R,13R,14S,17R)-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7,9,11(18),15-tetraene-10,14-diol","(7R,7AS,12bs)-3-methyl-2,3,4,4a,7,7a-hexahydro-1H-4,12-methano(1)benzofuro(3,2-e)isoquinoline-7,9-diol","SDZ202-250","Morphine base","Opium Tincture Deodorized","Dtxcid203336","SDZ202250","SDZ 202250","SDZ202 250","Sdz 202 250","Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl-(5α,6α)-","(1S,5R,13R,14S,17R)-4-methyl-12-oxa-4-azapentacyclo(9.6.1.01,13.05,17.07,18)octadeca-7(18),8,10,15-tetraene-10,14-diol","(4R,4aR,7S,7aR,12bS)-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro(3,2-e)isoquinoline-7,9-diol","200-320-2","NSC11411","MS Contin","Dreamer","Hocus","Unkie","Cube juice","Hard stuff","Ms Emma","CCRIS 5762","HSDB 2134","CHEMBL70","Morphine Anhydrate","RMS","Morphinan-3,6-α-diol, 7,8-didehydro-4,5-α-epoxy-17-methyl-","Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl-, (5α,6α)-","methyl[?]diol","(5α,6α)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol","MOI","Einecs 200-320-2","DEA No. 9300","(Morphine)","Morphine polistirex","Substitol","(etorphine)","(-)Morphine sulfate","Epitope ID:116646","Schembl2997","Bidd:gt0147","GTPL1627","Schembl4740781","Schembl11684914","Schembl27850914","Schembl29350575","Morphine 0.1 mg/ml in Methanol","Morphine 1.0 mg/ml in Methanol","BDBM579485","17-methyl-7,8-didehydro-4,5α-epoxymorphinan-3,6α-diol","US11484525, Compound Morphine","7,8-Didehydro-4,5α-epoxy-17-methylmorphinan-3,6α-diol","Bdbm50000092","Akos015966554","DB00295","NS00000380","C01516","D08233","Hydromorphone hydrochloride impurity, morphine-","Codeine monohydrate impurity b","7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol","Ethylmorphine hydrochloride impurity b","Hydromorphone hydrochloride impurity c","Codeine hydrochloride dihydrate impurity b","Codeine phosphate hemihydrate impurity b","Codeine phosphate sesquihydrate impurity b","17-Methyl-5α-7,8-didehydro-4,5-epoxymorphinan-3,6α-diol","7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)","Dihydrocodeine hydrogen tartrate impurity b","(5α,6β)-17-methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol","3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester","4,5α-Epoxy-17-methyl-7,8-didehydromorphinan-3,6α-dio","6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine","Apomorphine hydrochloride hemihydrate impurity b","Hydrocodone hydrogen tartrate 2.5-hydrate impurity a","(-)(5α,6α)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol","Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl, (5α,6α)-","Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl- (5.α,6α)-","(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol","(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol","2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)","4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol","4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride","4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)","4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))","4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine sulfate)","4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)","4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)","4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)","4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine","4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol","4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)","6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)","9H-9,9c-Iminoethanophenanthro(4,5-bcd)furan-3,5-diol, 4α,5,7α,8-tetrahydro-12-methyl-","Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol"],"Associated Disorders and Diseases":"Asthma, occupational [Category: Airway Disease]","Biological Half-Life":"Morphine has a half life of 2-3 hours.","Boiling Point":"190ºC","CAS":"57-27-2","Chemical Classes":"Biological Agents -\u003e Plant Toxins","ChemicalClasses":["morphinan"],"Chirality":"absolute","Classes":["Opioid"],"Color/Form":"Prisms","DBI-IGS":["Morphine"],"DTXSID":"9023336","Decomposition":"When heated to decomposition it emits toxic fumes of /nitrogen oxide/.","Density":"1.32 at 20 °C/4 °C g/cm\u003csup\u003e3\u003c/sup\u003e","Dosing Info":[{"Method":"Intravenous","Tiers":{"Common":{"Entries":0,"Lower":4,"Percentage":0,"Unit":"mg","Upper":4},"Extreme":{"Entries":1,"Lower":4.7,"Percentage":25,"Unit":"mg","Upper":4.7},"Heavy":{"Entries":0,"Lower":4.3,"Percentage":0,"Unit":"mg","Upper":4.7},"Light":{"Entries":3,"Lower":4,"Percentage":75,"Unit":"mg","Upper":4},"Strong":{"Entries":0,"Lower":4,"Percentage":0,"Unit":"mg","Upper":4.3}}},{"Method":"Oral","Tiers":{"Common":{"Entries":0,"Lower":150,"Percentage":0,"Unit":"mg","Upper":150},"Extreme":{"Entries":31,"Lower":198.7,"Percentage":14.4,"Unit":"mg","Upper":198.7},"Heavy":{"Entries":0,"Lower":150,"Percentage":0,"Unit":"mg","Upper":198.7},"Light":{"Entries":185,"Lower":150,"Percentage":85.6,"Unit":"mg","Upper":150},"Strong":{"Entries":0,"Lower":150,"Percentage":0,"Unit":"mg","Upper":150}}},{"Method":"Intrarectal","Tiers":{"Common":{"Entries":0,"Lower":61.9,"Percentage":0,"Unit":"mg","Upper":67.5},"Extreme":{"Entries":1,"Lower":82,"Percentage":25,"Unit":"mg","Upper":82},"Heavy":{"Entries":0,"Lower":77.5,"Percentage":0,"Unit":"mg","Upper":82},"Light":{"Entries":2,"Lower":61.9,"Percentage":50,"Unit":"mg","Upper":61.9},"Strong":{"Entries":1,"Lower":67.5,"Percentage":25,"Unit":"mg","Upper":77.5}}}],"Drug Classes":["Breast Feeding","Lactation","Milk, Human","Analgesics, Opioid","Narcotics"],"Drug Indication":"Morphine is used for the management of chronic, moderate to severe pain.  Opiods, including morphine, are effective for the short term management of pain. Patients taking opioids long term may need to be monitored for the development of physical dependence, addiction disorder, and drug abuse.","Drug Warnings":"The U.S. Food and Drug Administration (FDA) is warning about several safety issues with the entire class of opioid pain medicines. These safety risks are potentially harmful interactions with numerous other medications, problems with the adrenal glands, and decreased sex hormone levels. We are requiring changes to the labels of all opioid drugs to warn about these risks. Opioids can interact with antidepressants and migraine medicines to cause a serious central nervous system reaction called serotonin syndrome, in which high levels of the chemical serotonin build up in the brain and cause toxicity. Taking opioids may lead to a rare, but serious condition in which the adrenal glands do not produce adequate amounts of the hormone cortisol. Cortisol helps the body respond to stress. Long-term use of opioids may be associated with decreased sex hormone levels and symptoms such as reduced interest in sex, impotence, or infertility.","Druglikeness":{"Lipinski":{"Passes":true,"Violations":0}},"Erowid Experience Reports":[],"Esters":[],"European Community (EC) Number":"200-320-2","FDA Pharmacological Classification":[{"Name":"FDA UNII","ReferenceNumber":31,"Value":{"StringWithMarkup":[{"String":"76I7G6D29C"}]}},{"Name":"Active Moiety","ReferenceNumber":31,"Value":{"StringWithMarkup":[{"String":"MORPHINE"}]}},{"Name":"Pharmacological Classes","ReferenceNumber":31,"Value":{"StringWithMarkup":[{"String":"Mechanisms of Action [MoA] - Full Opioid Agonists"}]}},{"Name":"Pharmacological Classes","ReferenceNumber":31,"Value":{"StringWithMarkup":[{"String":"Established Pharmacologic Class [EPC] - Opioid Agonist"}]}},{"Name":"FDA Pharmacology Summary","ReferenceNumber":31,"Value":{"StringWithMarkup":[{"Markup":[{"Extra":"CID-5288826","Length":8,"Start":0,"Type":"PubChem Internal Link","URL":"https://pubchem.ncbi.nlm.nih.gov/compound/Morphine"},{"Extra":"CID-5288826","Length":8,"Start":58,"Type":"PubChem Internal Link","URL":"https://pubchem.ncbi.nlm.nih.gov/compound/morphine"}],"String":"Morphine is an Opioid Agonist. The mechanism of action of morphine is as a Full Opioid Agonist."}]}},{"Name":"Non-Proprietary Name","ReferenceNumber":101,"Value":{"StringWithMarkup":[{"String":"MORPHINE"}]}},{"Name":"Pharmacological Classes","ReferenceNumber":101,"Value":{"StringWithMarkup":[{"String":"Opioid Agonist [EPC]; Full Opioid Agonists [MoA]"}]}},{"Name":"Non-Proprietary Name","ReferenceNumber":102,"Value":{"StringWithMarkup":[{"String":"MORPHINE TINCTURE"}]}},{"Name":"Pharmacological Classes","ReferenceNumber":102,"Value":{"StringWithMarkup":[{"String":"Full Opioid Agonists [MoA]; Opioid Agonist [EPC]"}]}}],"Formating":[],"HMDB ID":"HMDB0014440","Health Effects":"Medical problems can include congested lungs, liver disease, tetanus, infection of the heart valves, skin abscesses, anemia and pneumonia. Death can occur from overdose.","HeavyAtomCount":21,"Human Drugs":"Breast Feeding; Lactation; Milk, Human; Analgesics, Opioid; Narcotics","Human Toxicity Values":"Therapeutic or normal morphine blood concentration: 1-7 ug/dL; Toxic morphine blood concentration: 10-100 ug/dL; Lethal morphine blood concentration: \u003e 400 ug/dL /From table/","IUPACName":"(4R,4aR,7S,7aR,12bS)-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9-diol","Impurities":"codeine; 7,7',8,8'-tetrahydro-4,5alpha:4',5'alpha-diepoxy-17,17'-dimethyl-2,2'-bimorphinanyl-3,3',6alpha,6'alpha-tetrol (pseudomorphine); 6,7,8,14-tetrahydro-4,5alpha-epoxy-6-methoxy-17-methylmorphinan-3-ol (oripavine); 7,8-didehydro-4,5alpha-epoxy-17-methylmorphinan-3,6alpha,10beta-triol (10R-hydroxymorphine); 7,8-didehydro-4,5alpha-epoxy-17-methyl-6-oxomorphinan-3-ol (morphinone) /morphine hydrochloride; morphine sulfate/","InChI":"InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1","InChIKey":"BQJCRHHNABKAKU-KBQPJGBKSA-N","Interactions":"Deaths due to ingesting rachacha, which is a homemade paste obtained by decocting poppy heads, are very rare. No fatalities have been recorded in scientific publications. This product is not considered to be very dangerous by its users. We are reporting the first deaths (a 30-year-old man and a 28-year-old woman), after ingesting rachacha balls and alcohol consumption during an evening with a friend. Signs compatible with acute anoxia were observed during autopsy. Toxicological analyses highlighted the presence of morphine and codeine in the blood, urine and bile, with an absence of 6-acetylmorphine. Concomitant consumption of alcohol certainly played a role in the occurrence of death. The black paste found at the scene was identified as rachacha. The mean of consumption (orally) was confirmed by the presence of morphine and codeine in the gastric contents of both victims. The analysis of hair samples was performed to reveal the substance consumption history. Therefore, a possibility of contamination by sweat and/or putrefactive liquids in the post-mortem period must be considered for the interpretation of the results. These two cases show that taking rachacha can be dangerous, especially when combined with the consumption of substances which could potentiate respiratory depression induced by morphine.","MeSH Headers":[{"Id":"M0014064","Link":"https://id.nlm.nih.gov/mesh/M0014064.html","Name":"Morphine","Ref":140},{"Id":"M0052581","Link":"https://id.nlm.nih.gov/mesh/M0052581.html","Name":"nepenthe","Ref":141},{"Id":"DescTree","Link":"https://www.nlm.nih.gov/mesh/meshhome.html","Name":"MeSH Tree","Ref":143},{"Id":"PubMed from MeSH","Link":"https://www.nlm.nih.gov/mesh/meshhome.html","Name":null,"Ref":174},{"Id":"M0001068","Link":"https://id.nlm.nih.gov/mesh/M0001068.html","Name":"Analgesics, Opioid","Ref":175},{"Id":"M0014481","Link":"https://id.nlm.nih.gov/mesh/M0014481.html","Name":"Narcotics","Ref":176}],"MeSH Pharmacological Classification":[{"Id":"M0001068","Link":"https://id.nlm.nih.gov/mesh/M0001068.html","Name":"Analgesics, Opioid","Ref":175},{"Id":"M0014481","Link":"https://id.nlm.nih.gov/mesh/M0014481.html","Name":"Narcotic","Ref":176}],"Mechanism of Action":"Morphine-6-glucuronide is responsible for approximately 85% of the response observed by morphine administration. Morphine and its metabolites act as agonists of the mu and kappa opioid receptors. The mu-opioid receptor is integral to morphine's effects on the ventral tegmental area of the brain. Morphine's activation of the reward pathway is mediated by agonism of the delta-opioid receptor in the nucleus accumbens, while modification of the respiratory system and addiction disorder are mediated by agonism of the mu-opioid receptor.","Melting Point":"255 °C","Metabolism/Metabolites":"Morphine is 90% metabolized by glucuronidation by UGT2B7 and sulfation at positions 3 and 6. Morphine can also be metabolized to codeine, normorphine, and morphine ethereal sulfate.","MolecularFormula":"C\u003csub\u003e17\u003c/sub\u003eH\u003csub\u003e19\u003c/sub\u003eNO\u003csub\u003e3\u003c/sub\u003e","MolecularWeight":"285.34 g/mol","Non-Human Toxicity Values":"LD50 Rat oral 335 mg/kg","Odor":"Odorless","Opticalactivity":"UNSPECIFIED","Passes":true,"Pharmacodynamics":"Morphine binding to opioid receptors blocks transmission of nociceptive signals, signals pain-modulating neurons in the spinal cord, and inhibits primary afferent nociceptors to the dorsal horn sensory projection cells.  Morphine has a time to onset of 6-30 minutes. Excess consumption of morphine and other opioids can lead to changes in synaptic neuroplasticity, including changes in neuron density, changes at postsynaptic sites, and changes at dendritic terminals.  Intravenous morphine's analgesic effect is sex dependent. The EC\u003csub\u003e50\u003c/sub\u003e in men is 76ng/mL and in women is 22ng/mL.  Morphine-6-glucuronide is 22 times less potent than morphine in eliciting pupil constriction.","Physical Description":"Solid","PubChemId":5288826,"PubChemTitle":"Morphine","Record Description":["LiverTox|Analgesic|Severe pain|Opiate"],"Records":{"UNII":{"Impurities":[]}},"Reddit Experience Reports":[{"author":"Hangeth_Thy_Dong","body_length":6304,"dose_notes":["vague dose: 10.0 strip — no substance or weight specified","vague dose: 5.0 tab — no substance or weight specified","partial dose: 7.0 g — substance not identified","partial dose: 5.0 g — substance not identified","partial dose: 75.0 g — substance not identified","partial dose: 750.0 mg — substance not identified","partial dose: 700.0 mg — substance not identified"],"doselog":null,"doses":[{"amount":3.5,"quality":"precise","substance":"weed","unit":"g"},{"amount":7,"quality":"partial","unit":"g"},{"amount":1,"quality":"precise","route":"oral","substance":"Psilocybin","unit":"oz"},{"amount":5,"quality":"partial","unit":"g"},{"amount":10,"quality":"vague","unit":"strip"},{"amount":25,"quality":"precise","substance":"2C-B","unit":"mg"},{"amount":2,"quality":"precise","substance":"DMT","unit":"oz"},{"amount":100,"quality":"precise","substance":"Kratom","unit":"g"},{"amount":75,"quality":"partial","route":"oral","unit":"g"},{"amount":5,"quality":"vague","route":"oral","unit":"tab"},{"amount":750,"quality":"partial","unit":"mg"},{"amount":700,"quality":"partial","unit":"mg"}],"flair":"Other Psychedelic","headers":null,"id":"gkqlsz","num_comments":88,"prep_flags":["empty_stomach"],"pubdate":"2020-05-16","routes":["intramuscular","oral","smoked"],"score":51,"substances":["25I-NBOMe","2C-B","Alcohol","Alprazolam","Amphetamine","Benzodiazepines","Cannabinoids","Cannabis","Changa","Clenbuterol","Cocaine","DMT","GBL","GHB","Hydrocodone","Ketamine","Kratom","LSA","MDMA","Methamphetamine","Methylphenidate","Morphine","NBOMe","Nicotine","Nitrous Oxide","Oxygen","PCP","Psilocybin","Psilocybin Mushrooms","Salvia divinorum","Testosterone","Tobacco"],"time_format":null,"title":"I Have Tried Every Single Drug and Steroid","upvote_ratio":0.8999999761581421,"url":"https://reddit.com/r/tripreports/comments/gkqlsz/i_have_tried_every_single_drug_and_steroid/"},{"author":"AdministrationMany53","body_length":3852,"dose_notes":null,"doselog":[{"note":"4:00 pm - i started by taking two tums to help the absorption of the codeine","time":"T-0:20"},{"doses":[{"amount":100,"quality":"partial","unit":"mg"}],"note":"4:20 pm - i took some dxm to potentiate the other drugs i’ll be consuming later (100 mg)","time":"T+0:00"},{"doses":[{"amount":150,"quality":"precise","substance":"codeine","unit":"mg"}],"note":"4:30 pm - i took the amount of codeine i wanted (i did 150 mg) and chewed them before swallowing and i took some tylenol to help potentiate as well","time":"T+0:10"},{"note":"5:00 pm - i took a whole cotton of benzedrex paired with an acidic drink (pineapple and lemon juice w sprite) to make the affects (of above stimulant) stronger","time":"T+0:40"},{"doses":[{"amount":25,"quality":"precise","substance":"dph","unit":"mg"},{"amount":25,"quality":"precise","substance":"codeine","unit":"mg"}],"note":"5:05 pm - i took one hydroxyzine (25 mg) and one dph (25 mg). you’re gonna want to take these after the codeine because although they potentiate the drug, taking it before absorption of codeine will cause less to be absorbed but taking it after will allow time for codeine to turn to morphine and those antihistamines will prolong the high due to slowing down the process of morphine being released.","time":"T+0:45"},{"doses":[{"amount":100,"quality":"precise","substance":"dxm","unit":"mg"},{"amount":50,"quality":"precise","substance":"dxm","unit":"mg"}],"note":"5:15 pm - by now i’m starting to feel a little something so i take a few hits off my pen, took one more hydroxyzine and four more dph (100 mg). i also took 50 mg of dxm","time":"T+0:55"},{"note":"5:30 pm - i’m hitting my vape and i feel great, like amazing. i go outside and pack a few bowls and when i come back inside and just lay down, being enveloped in euphoria. at this point due to the stim i’m not tired and i’m feeling both the effects of the stim and the depressant while everything else is helping boost those two. yes it’s dangerous but if done right (and not often) it can be very enjoyable","time":"T+1:10"},{"doses":[{"amount":75,"quality":"precise","substance":"dph","unit":"mg"}],"note":"6:30 pm - i’ve spent the last hour smoking, taking pictures and looking at myself lol, i was very happy and was not feeling any adverse effects. i ate a little and i wasn’t nauseating to eat as it would have been on the stim alone. i’m laying down watching yt and contemplating on taking more dph so i do (75 mg) then i drink some coffee, hit my pen and hit my vape","time":"T+2:10"},{"note":"8:30 pm - by this time i’m j riding on my high. i’m no longer adding any substance (except nic) and i’m very content where i’m at. i’m slurring slightly and i’m having minimal motor complications but i don’t feel sick in the slightest. this lasts for a little while longer before i begin to feel the comedown","time":"T+4:10"},{"note":"10:30 pm - so i’m coming down but slowly (thanks to preparations) and i’m slightly tired but not really. i wanted to take a vyvanse to kick my energy back up but i decided not to. i wasn’t wide awake but i also wasn’t completely sedated so i rode the high out until i eventually fell asleep","time":"T+6:10"},{"note":"4:00 am - i’m not sure what time i fell asleep but ik i woke up around 4 am and i still had a nice little high/buzz going. i was a bit disoriented at first and had some brain fog but that went away sooner than later. the only side effect i felt was sleepiness so, i went back to sleep lol","time":"T+11:40"},{"note":"8:00 am - i’m still a little groggy but after resting a little longer, drinking some water and eating healthy food i felt a lot better. also caffeine and nic helps too but i wouldn’t do too much just because of the previous night lol. like take it a little easy. i wouldn’t do this back to back but like maybe twice - three times a week ? then a tolerance break for a week lol and if you were to do it back to back at least wait 24 hrs. and if you know you’re going to be redosing frequently don’t start your first trip w a 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I was in so much pain I couldn’t sit normal and was in agony. Of course this is when he decides to go 65 on the highway when normally he does 80+. Why the fuck would you speed during the day to a restaurant or something not urgent and then go slow as shit to the hospital with nobody on the road?","time":"T+0:30"},{"note":"I had to go to the urgent care 30 minutes away because the one by my house isn’t open 24 hours and is for more minor stuff. When I got there they did an X ray where they put the machine behind my back where I don’t have to get up. The nurse came in and asked to talk to my mom outside the room and when she came back in my mom was crying. I asked why she was crying and she told me “it’s because you’re really sick” I told her “it’s fine I just have pneumonia I’ll be fine”. 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class=\"hi\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Subjective Effects":{"Cognitive Effects":["Cognitive euphoria","Thought deceleration","Anxiety suppression","Compulsive redosing","Increased music appreciation"],"Physical Effects":["Respiratory depression","Pain relief","Itchiness","Constipation","Cough suppression","Sedation","Nausea","Pupil constriction","Stomach cramp","Difficulty urinating"],"Visual Effects":["Double vision"]},"Taste":"Bitter","Therapeutic Uses":"Analgesics, Opioid; Narcotics","Title":"Morphine","Toxicity Data":"LD50: 461 mg/kg (oral, rat)\nLD50: 600 mg/kg (oral, mouse)","Treatment":"In the treatment of morphine overdosage, primary attention should be given to the re- establishment of a patent airway and institution of assisted or controlled ventilation. Supportive measures (including oxygen, vasopressors) should be employed in the management of circulatory shock and pulmonary edema accompanying overdose as indicated. Cardiac arrest or arrhythmias may require cardiac massage or defibrillation. The pure opioid antagonists, such as naloxone, are specific antidotes against respiratory depression which results from opioid overdose. Naloxone should be administered intravenously; however, because its duration of action is relatively short, the patient must be carefully monitored until spontaneous respiration is reliably re-established. If the response to naloxone is suboptimal or not sustained, additional naloxone may be administered, as needed, or given by continuous infusion to maintain alertness and respiratory function; however, there is no information available about the cumulative dose of naloxone that may be safely administered. (L1712)","UNII":"76I7G6D29C","Violations":0,"Wikidata":"Q81225","Wikipedia":"Morphine","XLogP":0.8,"pH":"pH of saturated solution: 8.5"}
