{"Abbreviation":[],"Aliases":["3-Hydroxyacetanilide","acetyl-m-aminophenol","RefChem:811192","3-Acetamidophenol","N-(3-Hydroxyphenyl)acetamide","3'-Hydroxyacetanilide","N-Acetyl-m-aminophenol","Acetamide, N-(3-hydroxyphenyl)-","m-Acetamidophenol","3-(Acetylamino)phenol","M-hydroxyacetanilide","Metalid","Pedituss","Pyrapap","Rystal","m-(Acetylamino)phenol","BS 749","Metacetamolum","Acetanilide, 3'-hydroxy-","3-(Acetylamino)-1-hydroxybenzene","BS-749","Metacetamol;3'-Hydroxyacetanilide","BS 479","Ncgc00091423-02","m-Acetaminophenol"],"CAS":"621-42-1","ChEBI":"CHEBI:76987","ChEMBL":"CHEMBL9419","ChemicalClasses":["aniline"],"Chirality":"achiral","EINECS":"210-687-0","Esters":[],"European Community (EC) Number":"210-687-0","Formating":[],"HMDB ID":"HMDB0245795","HeavyAtomCount":11,"IUPACName":"N-(3-hydroxyphenyl)acetamide","InChI":"InChI=1S/C8H9NO2/c1-6(10)9-7-3-2-4-8(11)5-7/h2-5,11H,1H3,(H,9,10)","InChIKey":"QLNWXBAGRTUKKI-UHFFFAOYSA-N","LD50":[{"dosages":[{"amount":"1025 mg/kg","route":"intraperitoneal"}],"organism":"Mouse"}],"MeSH Pharmacological Classification":"Compounds capable of relieving pain without the loss of CONSCIOUSNESS.","Melting Point":"406 °","MolecularFormula":"C\u003csub\u003e8\u003c/sub\u003eH\u003csub\u003e9\u003c/sub\u003eNO\u003csub\u003e2\u003c/sub\u003e","MolecularWeight":"151.16 g/mol","Physical Description":"N-acetyl-m-aminophenol is a light gray solid. (NTP, 1992)","PubChemId":12124,"RefCount":3,"RefCur":"","References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Metacetamol","Name":"Metacetamol","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q27146503","Name":"Metacetamol","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/12124","Name":"Metacetamol","Sub":false}]},{"Name":"ChEMBL","Urls":[{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL9419","Name":"Metacetamol","Sub":false}]},{"Name":"ChEBI","Urls":[{"Link":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:76987","Name":"Metacetamol","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=621-42-1","Name":"Metacetamol","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0245795","Name":"Metacetamol","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/V942ZCN81H","Name":"Metacetamol","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID3022089","Name":"Metacetamol","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 12124, Metacetamol. Accessed September 13, 2025. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/12124\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/12124\u003c/a\u003e","U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Metacetamol. UNII: V942ZCN81H. Global Substance Registration System. Accessed September 13, 2025. \u003ca href=https://gsrs.ncats.nih.gov/ginas/app/beta/substances/V942ZCN81H\u003ehttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/V942ZCN81H\u003c/a\u003e"],"SMILES":"CC(=O)NC1=CC(=CC=C1)O","SaltData":[],"Salts":[],"Solubility":"less than 1 mg/mL at 72 °F (NTP, 1992)","StereoisomerData":[],"Stereoisomers":[],"Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 54.874 74.751\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#ff0d0d\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h55v75H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"m53.836 3.081-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M40.638 12.109 30.106 6.028M41.857 9.997 31.325 3.916\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"m30.106 6.028 5.266 3.041M31.325 3.916l5.266 3.041\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath d=\"M40.638 10.701v11.39M37.484 27.762 27.44 33.561\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m27.444 48.81-.004-15.249M25.006 47.402l-.004-12.433\"/\u003e\u003c/g\u003e\u003cpath d=\"m27.444 48.81-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m1.043 48.801 13.203 7.629M3.481 47.394l10.766 6.22\"/\u003e\u003c/g\u003e\u003cpath d=\"m1.043 48.801-.005-15.248\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m14.236 25.933-13.198 7.62M14.236 28.749 3.477 34.96\"/\u003e\u003c/g\u003e\u003cpath d=\"m27.44 33.561-13.204-7.628M14.246 56.43l-.002 11.318\" class=\"bond\"/\u003e\u003cpath stroke=\"none\" d=\"M29.699 3.078q0 .756-.256 1.328-.256.565-.756.881-.5.315-1.245.315-.756 0-1.262-.315-.506-.316-.756-.887-.244-.572-.244-1.334 0-.75.244-1.309.25-.566.756-.881T27.454.56q.733 0 1.233.316.5.309.756.875.256.565.256 1.327m-3.864 0q0 .923.387 1.459.393.53 1.22.53.84 0 1.221-.53.387-.536.387-1.459 0-.929-.387-1.452-.381-.524-1.209-.524-.833 0-1.226.524-.393.523-.393 1.452\" class=\"atom\"/\u003e\u003cg fill=\"#3050f8\" stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M42.578 28.391h-.72l-2.619-4.066h-.03l.03.595q.024.357.024.732v2.739h-.566v-4.9h.714l2.608 4.055h.03l-.018-.328-.024-.476q-.006-.262-.006-.482v-2.769h.577zM46.885 28.391h-.619v-2.286h-2.513v2.286h-.613v-4.9h.613v2.072h2.513v-2.072h.619z\"/\u003e\u003c/g\u003e\u003cg stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M16.503 71.667q0 .756-.256 1.327-.256.566-.756.881t-1.244.316q-.756 0-1.262-.316-.506-.315-.756-.887-.244-.571-.244-1.333 0-.75.244-1.31.25-.566.756-.881t1.274-.316q.732 0 1.232.316.5.31.756.875.256.566.256 1.328m-3.864 0q0 .922.387 1.458.393.53 1.221.53.839 0 1.22-.53.387-.536.387-1.458 0-.929-.387-1.453-.381-.524-1.208-.524-.834 0-1.227.524t-.393 1.453M20.809 74.119h-.619v-2.286h-2.512v2.286h-.613V69.22h.613v2.072h2.512V69.22h.619z\"/\u003e\u003c/g\u003e\u003cpath stroke=\"#3050f8\" d=\"M40.638 22.091v-5.695M37.484 27.762l-5.022 2.9\" class=\"hi\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"m14.244 67.748.001-5.659\" class=\"hi\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Title":"Metacetamol","UNII":"V942ZCN81H","Wikidata":"Q27146503","Wikipedia":"Metacetamol","XLogP":0.7}