{"Abbreviation":["5-MeO-DMT"],"Aliases":["O-Methylbufotenine","5-Methoxy-N,N-dimethyltryptamine","N,N-Dimethyl-5-methoxytryptamine","5-MeO-DMT","MeODMT","Methylbufotenine","Bufotenine, O-methyl-","3-(2-Dimethylaminoethyl)-5-methoxyindole","2-(5-Methoxy-1H-indol-3-yl)-N,N-dimethylethanamine","1H-Indole-3-ethanamine, 5-methoxy-N,N-dimethyl-","CT 4334","5-Methoxy-N,N-dimethyl-1H-indole-3-ethanamine","NSC 88624","Einecs 213-813-2","NSC-88624","5-Methoxy-N,N-dimethyl-1H-indole-3-ethylamine","3-(2-(N,N-Dimethyl)aminoethyl)-5-methoxyindole","Brn 0164771","Indole, 3-(2-(n,n-dimethylamino)ethyl)-5-methoxy-","5-Methoxy-n-dimethyltryptamine","Indole, 3-(2-(dimethylamino)ethyl)-5-methoxy-","3-[2-(N,N-Dimethylamino)ethyl]-5-methoxy-indole","CHEBI:2086","Dtxsid70144324","Indole, 3-[2-(dimethylamino)ethyl]-5-methoxy-","5-22-12-00027","[2-(5-Methoxy-1h-indol-3-yl)-ethyl]-dimethyl-amine","3-(2-(N,N-Dimethylamino)ethyl)-5-methoxy-indole","(2-(5-Methoxy-1H-Indol-3-Yl)-Ethyl)-Dimethyl-Amine","5-OMe-DMT","Dtxcid1066815","Indole, 3-(2-(dimethylamino)ethyl)-5-methoxy-(8CI)","1H-Indole-3-ethanamine, 5-methoxy-N,N-dimethyl-(9CI)","Methoxybufotenin","5-Methoxydimethyltryptamine","Mebufotenin","2-(5-methoxy-1H-indol-3-yl)-N,N-dimethylethan-1-amine","CHEMBL7257","Mls000069438","2-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-ethanamine","Smr000059066","[2-(5-methoxyindol-3-yl)ethyl]dimethylamine","Methoxydimethyltryptamine","3-(2-(N,N-Dimethylamino)ethyl)-5-methoxyindole","3-[2-(N,N-Dimethylamino)ethyl]-5-methoxyindole","Unii-x0mkx3gwu9","Mebufotenina","Mebufotenine","YFW","mebufotenin","5-methoxy bufotenine","Maybridge3_000045","Lopac-M-2381","cid_1832","Lopac0_000724","Oprea1_596468","GTPL145","[2-(5-methoxy-1H-indol-3-yl)ethyl]dimethylamine","Schembl132733","Schembl29261895","Schembl29351950","BDBM30707","HMS1431C01","HMS2235C20","HMS3370M04","N,N-Dimethyl-5-methoxy tryptamine","NSC88624","Mfcd00005658","Pdsp1_000032","Pdsp1_000447","Pdsp2_000032","Pdsp2_000445","SBB003367","STK368074","Akos005203483","Bufotenine, 5-Methoxydimethyltryptamine","CCG-204809","DB14010","Sdccgmls-0003129.p003","Idi1_011432","Wln: t56 bmj d2n1\u00261 go1","Ncgc00015654-01","Ncgc00015654-02","Ncgc00015654-03","Ncgc00015654-04","Ncgc00015654-05","Ncgc00015654-06","Ncgc00023288-03","Ncgc00023288-04","Indole,N-dimethylamino)ethyl]-5-methoxy-","DB-005455","NS00023092","ST50308247","C08309","5380","2-(5-methoxy-1H-indol-3-yl)ethyl-dimethyl-amine","5-methoxyindole 3-(2-(N,N-Dimethylamino)ethyl)","L000724","2-(5-methoxy-1H-indol-3-yl)-ethyl-dimethyl-amine","Brd-k34224286-001-07-1","2-(5-Methoxy-1H-indol-3-yl)-N,N-dimethylethanamine #"],"CAS":"1019-45-0","ChemicalClasses":["tryptamine"],"Chirality":"achiral","Classes":["Psychedelic"],"Drug Classes":["Breast Feeding","Lactation","Milk, Human","Hallucinogens","Serotonin Antagonists"],"DurationOfAction":"* Inhalational administration|Inhalation: 5 – 30 min, but up - 1 – 2 hours\n* Intranasal administration|Intranasal: 45 – 70 min\n* Intramuscular injection|Intramuscular: ≤60 min\n* Intravenous injection|Intravenous: 10 min\n* Oral administration|Oral (with harmaline) ≥3 – 4 hours","EliminationHalfLife":"* General: Minutes (12 – 19 min in mice, 6 – 16 min in rats)\n* Sublingual administration|Sublingual: 28 min\u003ca href='#cite_note-4'\u003e\u003csup\u003e[4]\u003c/sup\u003e\u003c/a\u003e","Esters":[],"European Community (EC) Number":"213-813-2","Formating":[],"HMDB ID":"HMDB0002004","HeavyAtomCount":16,"Human Drugs":"Breast Feeding; Lactation; Milk, Human; Hallucinogens; Serotonin Antagonists","IUPACName":"2-(5-methoxy-1H-indol-3-yl)-N,N-dimethylethanamine","InChI":"InChI=1S/C13H18N2O/c1-15(2)7-6-10-9-14-13-5-4-11(16-3)8-12(10)13/h4-5,8-9,14H,6-7H2,1-3H3","InChIKey":"ZSTKHSQDNIGFLM-UHFFFAOYSA-N","MeSH Headers":[{"Id":"M0013603","Link":"https://id.nlm.nih.gov/mesh/M0013603.html","Name":"Methoxydimethyltryptamines","Ref":74},{"Id":"M0013602","Link":"https://id.nlm.nih.gov/mesh/M0013602.html","Name":"Methylbufotenin","Ref":75}],"Metabolism/Metabolites":"N,n-dimethyl-5-methoxytryptamine has known human metabolites that include Bufotenine.","MolecularFormula":"C\u003csub\u003e13\u003c/sub\u003eH\u003csub\u003e18\u003c/sub\u003eN\u003csub\u003e2\u003c/sub\u003eO","MolecularWeight":"218.29 g/mol","Physical Description":"Solid","PubChemId":1832,"Record Description":["Wikipedia|List of designer drugs|Psychedelics|Tryptamines","Wikipedia|TiHKAL|Tryptamines"],"Records":{"UNII":{"Impurities":[]}},"RefChem":"855288","RefCount":5,"RefCur":"","References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/5-MeO-DMT","Name":"Mebufotenin","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q570757","Name":"Mebufotenin","Sub":false}]},{"Name":"DrugBank","Urls":[{"Link":"https://go.drugbank.com/DB14010","Name":"Mebufotenin","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/1832","Name":"Mebufotenin","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=1019-45-0","Name":"Mebufotenin","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0002004","Name":"Mebufotenin","Sub":false}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/C08309","Name":"Mebufotenin","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/X0MKX3GWU9","Name":"Mebufotenin","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID70144324","Name":"Mebufotenin","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 1832, O-Methylbufotenine. Accessed April 29, 2026. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/1832\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/1832\u003c/a\u003e","U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Mebufotenin. UNII: X0MKX3GWU9. Global Substance Registration System. Accessed April 29, 2026. \u003ca href=https://gsrs.ncats.nih.gov/ginas/app/beta/substances/X0MKX3GWU9\u003ehttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/X0MKX3GWU9\u003c/a\u003e","Anvisa. RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. July 24, 2023. Accessed April 29, 2026. \u003ca href=https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-804-de-24-de-julho-de-2023-498447451\u003ehttps://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-804-de-24-de-julho-de-2023-498447451\u003c/a\u003e","Bistue Millón MB, Noguera L, Bruno D, Vita L, Zanino M, Kassuha DE, Ortiz JE, Feresin GE, Díaz-Dellavalle P, Orosco L, Garcés MA, Diez P, Albarracín SG, Bruno MA. Safety and tolerability of multiple sublingual microdoses of 5-MeO-DMT in adults with moderate symptoms of depression and/or anxiety: a randomized, double-blind, placebo-controlled study. Neuropsychopharmacology. July 1, 2025; 50(11):1715–1723."],"SMILES":"CN(C)CCC1=CNC2=C1C=C(C=C2)OC","SaltData":[{"AcidCount":1,"Amine":"Mebufotenin","AmineCount":1,"Formula":"Cl","Name":"hydrochloride","RName":"hydrochloride","Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 130.884 63.847\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#3050f8\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h131v64H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"M106.937 42.63 96.9 36.819M93.753 31.144l.014-11.39M90.594 36.81 80.54 42.598M80.54 42.598l-13.188-7.636M67.352 34.962l-13.208 7.603\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m52.562 57.684 1.582-15.119M50.322 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