{"Aliases":["Levmetamfetamine","Methamphetamine","Methylamphetamine","levomethamphetamine","R(-)-N-Methylamphetamine","1-Phenyl-2-methylaminopropane","Vicks","Levmetamfetamine cii","NSC 6084","levmetanfetamina","1-Phenyl-2-methylamino-propan","Einecs 251-687-0","Unii-y24t9bt2q2","Benzeneethanamine, N,α-dimethyl-, (R)-","Benzeneethanamine, N,α-dimethyl-, (-)-","Phenethylamine, n,α-dimethyl-, (-)-","N,α-Dimethylphenethylamine","Dtxsid30187474","levmetamfetaminum","Sinu Inhaler","Vapor Inhaler","Nasal Decongestant Inhaler","Dtxcid40109965","Levmetamfetamine Nasal Decongestant","Vapor Inhalerlevmetamfetamine nasal decongestant, DG health","Vapor Inhalerlevmetamfetamine nasal decongestant, Equaline","Vapor Inhalerlevmetamfetamine nasal decongestant, Good Sense","Vapor Inhalerlevmetamfetamine nasal decongestant, Best Choice","Vapor Inhalerlevmetamfetamine nasal decongestant, TopCare health","251-687-0","Deoxyephedrine","r(-)-methamphetamine","Methyl(α-methylphenethyl)amine","Chembl1927030","N-Methyl-1-phenylpropan-2-amine","(-)-Methamphetamine","Desoxyephedrine","Vicks Inhaler","Selegiline hydrochloride EP Impurity A",")-amine","Methyl-((R)-1-methyl-2-phenyl-ethyl","1-Methamphetamine","N-Methylamphetamine","2R-(-)-Methamphetamine","Ncgc00247704-01","(-)-Deoxyephedrine","R-(-)-N-Methylamphetamine","Schembl727412","Schembl17045259","NSC6084","Chebi:136013","NSC-6084","Bdbm50359500","Akos015962949","Phenethylamine,α-dimethyl-, D-","DB09571","Deoxyephedrine, analytical standard","(2R)-N-methyl-1-phenyl-2-propanamine","2--(Methyl-amino)-1-phenylpropane","AC-18760","N-Methyl-1-phenyl-2-propanamine, (-)-","Phenethylamine,α-dimethyl-, (-)-","Benzeneethanamine,α-dimethyl-, (-)-","Benzeneethanamine,α-dimethyl-, (R)-","NS00070437","Phenethylamine, N,α-dimethyl-, (-)-","D02291","benzeneethanamine, N,α-dimethyl-, (αR)-","Benzeneethanamine, N,α-dimethyl-, (αR)-","Levmetamfetamine, United States Pharmacopeia (USP) Reference Standard"],"Biological Half-Life":"The elimination half-life of levomethamphetamine is between 13.3 and 15 hours.","CAS":"33817-09-3","ChemicalClasses":["amphetamine"],"Chirality":"absolute","Classes":["Stimulant"],"DBI-IGS":["Levomethamphetamine","Methamphetamine","Levomethamphetamine"],"Dosing Info":[],"Drug Indication":"Used over-the-counter for nasal congestion.","EliminationHalfLife":"10 – 15 hours","Esters":[],"European Community (EC) Number":"251-687-0","Formating":[],"Health Effects":"Using large amounts of these drugs can result in a condition known as amphetamine psychosis -- which can result in auditory, visual and tactile hallucinations, intense paranoia, irrational thoughts and beliefs, delusions, and mental confusion.","HeavyAtomCount":11,"IUPACName":"(2R)-N-methyl-1-phenylpropan-2-amine","InChI":"InChI=1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3/t9-/m1/s1","InChIKey":"MYWUZJCMWCOHBA-SECBINFHSA-N","MeSH Headers":[],"Mechanism of Action":"Levomethamphetamine crosses the blood-brain-barrier and acts as a TAAR1 agonist,[3] functioning as a selective norepinephrine releasing agent in the central nervous system,","Metabolism/Metabolites":"Methamphetamine is a known human metabolite of selegiline.","MolecularFormula":"C\u003csub\u003e10\u003c/sub\u003eH\u003csub\u003e15\u003c/sub\u003eN","MolecularWeight":"149.23 g/mol","Opticalactivity":"( - )","Pharmacodynamics":"Levomethamphetamine increases norepinephrine release resulting in increased vasocontriction.","PubChemId":36604,"Records":{"UNII":{"Impurities":["n-nitroso-levmetamfetamine"]}},"RefChem":"55470","RefCount":4,"RefCur":"","References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Levomethamphetamine","Name":"Levomethamphetamine","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q402846","Name":"Levomethamphetamine","Sub":false}]},{"Name":"DrugBank","Urls":[{"Link":"https://go.drugbank.com/DB09571","Name":"Levomethamphetamine","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/36604","Name":"Levomethamphetamine","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=33817-09-3","Name":"Levomethamphetamine","Sub":false}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/D02291","Name":"Levomethamphetamine","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/Y24T9BT2Q2","Name":"Levomethamphetamine","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID30187474","Name":"Levomethamphetamine","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 36604, Levmetamfetamine. Accessed April 29, 2026. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/36604\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/36604\u003c/a\u003e","U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Levomethamphetamine. UNII: Y24T9BT2Q2. Global Substance Registration System. Accessed April 29, 2026. \u003ca href=https://gsrs.ncats.nih.gov/ginas/app/beta/substances/Y24T9BT2Q2\u003ehttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/Y24T9BT2Q2\u003c/a\u003e","Anvisa. RDC Nº 877 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. May 28, 2024. Accessed April 29, 2026. \u003ca href=https://www.in.gov.br/en/web/dou/-/resolucao-da-diretoria-colegiada-anvisa-n-877-de-28-de-maio-de-2024-562758149\u003ehttps://www.in.gov.br/en/web/dou/-/resolucao-da-diretoria-colegiada-anvisa-n-877-de-28-de-maio-de-2024-562758149\u003c/a\u003e"],"SMILES":"C[C@H](CC1=CC=CC=C1)NC","SaltData":[{"AcidCount":1,"Amine":"Levomethamphetamine","AmineCount":1,"Formula":"Cl","Name":"hydrochloride","RName":"hydrochloride","Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 104.179 39.997\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#1ff01f\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h105v40H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cg 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Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#3050f8\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h82v40H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M54.186 16.091h-.7M54.436 18.268h-1.2M54.686 20.445h-1.7M54.936 22.622h-2.2M55.186 24.799h-2.7M55.436 26.977h-3.2M55.686 29.154h-3.7M55.936 31.331h-4.2\"/\u003e\u003c/g\u003e\u003cpath d=\"m53.836 16.091-13.198-7.62M40.638 8.471l-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M27.44 16.091 14.236 8.462M25.002 17.498l-10.766-6.22\"/\u003e\u003c/g\u003e\u003cpath d=\"m14.236 8.462-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m1.038 16.082.005 15.249M3.477 17.49l.004 12.433\"/\u003e\u003c/g\u003e\u003cpath d=\"m1.043 31.331 13.203 7.628\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m14.246 38.959 13.198-7.62M14.247 36.143l10.759-6.211\"/\u003e\u003c/g\u003e\u003cpath d=\"m27.44 16.091.004 15.248M53.836 16.091l10.045-5.8M70.187 10.291l10.045 5.8\" class=\"bond\"/\u003e\u003cg stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M68.975 10.921h-.72l-2.62-4.066h-.03l.03.595q.024.357.024.732v2.739h-.566v-4.9h.715l2.607 4.054h.03l-.018-.327-.024-.476q-.006-.262-.006-.483V6.021h.578zM68.838 5.459h-.619V3.173h-2.512v2.286h-.614V.56h.614v2.072h2.512V.56h.619z\"/\u003e\u003c/g\u003e\u003cpath stroke=\"#3050f8\" d=\"m63.881 10.291-5.023 2.9M63.881 10.291l-5.023 2.9M70.187 10.291l5.022 2.9M70.187 10.291l5.022 2.9\" class=\"hi\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Subjective Effects":{"Cognitive Effects":["Analysis enhancement","Ego inflation","Focus enhancement","Increased music appreciation","Motivation enhancement","Thought acceleration","Wakefulness","Disinhibition","Suggestibility suppression","Cognitive euphoria","Compulsive redosing","Mania"],"Physical Effects":["Increased libido","Stamina enhancement","Stimulation","Appetite suppression","Dehydration","Dry mouth","Restless legs","Shakiness","Teeth grinding","Abnormal heartbeat","Increased blood pressure","Increased heart rate","Vasoconstriction"],"Visual Effects":[]},"Title":"Levomethamphetamine","Treatment":"Management of acute methamphetamine intoxication is largely symptomatic and includes gastric evacuation, administration of activated charcoal, and sedation. Experience with hemodialysis or peritoneal dialysis is inadequate to permit recommendations in this regard. Acidification of urine increases methamphetamine excretion, but is believed to increase risk of acute renal failure if myoglobinuria is present. Intravenous phentolamine has been suggested for possible acute, severe hypertension, if this complicates methamphetamine overdosage. Usually a gradual drop in blood pressure will result when sufficient sedation has been achieved. Chlorpromazine has been reported to be useful in decreasing CNS stimulation and sympathomimetic effects. (L1712)","UNII":"Y24T9BT2Q2","Wikidata":"Q402846","Wikipedia":"Levomethamphetamine","XLogP":2.1}