{"Abbreviation":"Leu","Aliases":["DL-Leucine","Dl-leucine","AI3-26709","206-328-2","H-DL-Leu-OH","2-Amino-4-methylpentanoic acid","(RS)-Leucine","25322-63-8","(+-)-Leucine","( inverted exclamation markA)-Leucine"],"CAS":"328-39-2","ChEBI":"CHEBI:25017","ChEMBL":"CHEMBL46575","ChemicalClasses":["amino acid"],"Chirality":"racemic","ChiralityAminoAcid":true,"Classes":null,"Dosing Info":[],"DrugClasses":[],"EINECS":"206-328-2","Esters":["palmitate"],"European Community (EC) Number":"206-328-2","FullSalts":["Leucine hydrochloride"],"HeavyAtomCount":9,"IUPACName":"2-amino-4-methylpentanoic acid","InChI":"InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)","InChIKey":"ROHFNLRQFUQHCH-UHFFFAOYSA-N","MolecularFormula":"C\u003csub\u003e6\u003c/sub\u003eH\u003csub\u003e13\u003c/sub\u003eNO\u003csub\u003e2\u003c/sub\u003e","MolecularWeight":"131.17 g/mol","Opticalactivity":"( + / - )","PrevSalts":[],"PubChemId":857,"Record Description":["Leucine is a branched-chain amino acid that consists of glycine in which one of the hydrogens attached to the alpha-carbon is substituted by an isobutyl group. It has a role as a Daphnia magna metabolite. It is a branched-chain amino acid and an alpha-amino acid. It contains an isobutyl group. It is a conjugate base of a leucinium. It is a conjugate acid of a leucinate.","DL-Leucine has been reported in Drosophila melanogaster, Populus tremula, and other organisms with data available.","See also: Leucine (annotation moved to); D-Leucine (annotation moved to).","Leucine is a branched-chain amino acid that consists of glycine in which one of the hydrogens attached to the alpha-carbon is substituted by an isobutyl group. It has a role as a Daphnia magna metabolite. It is a branched-chain amino acid and an alpha-amino acid. It contains an isobutyl group. It is a conjugate base of a leucinium. It is a conjugate acid of a leucinate."],"References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Leucine","Name":"Leucine","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q60662890","Name":"Leucine","Sub":false},{"Link":"https://www.wikidata.org/wiki/Q16081973","Name":"D-Leucine","Sub":true},{"Link":"https://www.wikidata.org/wiki/Q483745","Name":"L-Leucine","Sub":true}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/857","Name":"Leucine","Sub":false},{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/439524","Name":"D-Leucine","Sub":true},{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/6106","Name":"L-Leucine","Sub":true}]},{"Name":"ChEMBL","Urls":[{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL46575","Name":"Leucine","Sub":false},{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1232258","Name":"D-Leucine","Sub":true},{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL291962","Name":"L-Leucine","Sub":true}]},{"Name":"ChEBI","Urls":[{"Link":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:25017","Name":"Leucine","Sub":false},{"Link":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:28225","Name":"D-Leucine","Sub":true},{"Link":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:15603","Name":"L-Leucine","Sub":true}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=328-39-2","Name":"Leucine","Sub":false},{"Link":"https://commonchemistry.cas.org/detail?cas_rn=328-38-1","Name":"D-Leucine","Sub":true},{"Link":"https://commonchemistry.cas.org/detail?cas_rn=61-90-5","Name":"L-Leucine","Sub":true}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/C16439","Name":"Leucine","Sub":false},{"Link":"https://www.kegg.jp/entry/C01570","Name":"D-Leucine","Sub":true},{"Link":"https://www.kegg.jp/entry/C00123","Name":"L-Leucine","Sub":true}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/1QSS9D5DR6","Name":"Leucine","Sub":false},{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/965COD96YA","Name":"D-Leucine","Sub":true},{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/GMW67QNF9C","Name":"L-Leucine","Sub":true}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID00859050","Name":"Leucine","Sub":false},{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID6046347","Name":"D-Leucine","Sub":true},{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID9023203","Name":"L-Leucine","Sub":true}]}],"SMILES":"CC(C)CC(C(=O)O)N","Salts":["hydrochloride"],"SaltsAcidCount":[1],"SaltsAmineCount":[1],"SaltsUNII":["N39KV97633"],"StereoisomerRacemic":"DL-Leucine","Stereoisomers":["D-Leucine","L-Leucine","DL-Leucine"],"StereoisomersUNII":["965COD96YA","GMW67QNF9C",""],"StoreUNII":["1QSS9D5DR6"],"StructureBase64":"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","Title":"Leucine","UNII":"1QSS9D5DR6","Wikidata":"Q60662890","Wikipedia":"Leucine","XLogP":-1.5}