{"Aliases":["Lactose","lactose","Milk sugar","Chebi:17716","β-D-Gal-(1-\u003e4)-D-Glc","β-D-Galp-(1-\u003e4)-D-Glcp","1-β-D-Galactopyranosyl-4-D-glucopyranose","β-D-galactopyranosyl-(1-\u003e4)-D-glucopyranose","Lactin","Anhydrous lactose","Lactose anhydrous","4-(β-D-Galactosido)-D-glucose","Aletobiose","Galactinum","Tablettose","Saccharum lactin","Fast-flo","Zeparox EP","Fast-flo Lactose","Lactose Fast-flo","Pharmatose 21","Pharmatose 450M","Dtxcid403193","Lactosum, anhydrous","GlyTouCan:G74621DY","J2B2A4N98G","G74621DY","200-559-2","3SY5LH9PMK","4-O-β-D-galactopyranosyl-D-glucose","63-42-3","Glucose, 4-O-β-D-galactopyranosyl-","Dtxsid2023193","Lactopress anhydrous","Lactose,anhydrous","Supertab 21an","Supertab 22an","Supertab 24an","Laktose","Lactobiose","Laktobiose","Milchzucker","β-Gal1,4-Glc","(Gal)1 (Glc)1","Chembl1159651","Lactosum anhydricum","4-O-β-D-galactopyranosyl-D-glucopyranose","Galβ1-4Glc","Galβ1-4-Glc","Gal(b1-4)Glc","Epitope ID:142487","Schembl8446","Dtxsid501015196","x-ray exposed (1000 rad)lactose","Bdbm50572952","Akos040732197","DB04465","4-O-ss-D-Galactopyranosyl-a-D-glucose","a-D-Lactose monohydrate, NF/USP EP JP","(2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-{[(2R,3S,4R,5R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}oxane-3,4,5-triol","DB-230566","4-O-(β-D-galactopyranosyl)-D-glucopyranose","C00243","D00046","En300-19650781","Q27890379","F_full_20000000000000_gs_4019","Lactulose EP Impurity C; 4-O-|A-D-Galactopyranosyl-D-Glucopyranose","(3R,4R,5S,6R)-6-(hydroxymethyl)-5-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2,3,4-triol"],"CAS":"64044-51-5","Chemical Classes":"Biological Agents -\u003e Disaccharides","ChemicalClasses":[],"Chirality":"racemic","Color/Form":"White, hard, crystalline mass of white powder","Density":"1.525 g/cm\u003csup\u003e3\u003c/sup\u003e","Esters":[],"European Community (EC) Number":"200-559-2","Formating":[],"HeavyAtomCount":23,"IUPACName":"(2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-[(2R,3S,4R,5R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol","InChI":"InChI=1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3-,4-,5+,6+,7-,8-,9-,10-,11?,12+/m1/s1","InChIKey":"GUBGYTABKSRVRQ-QKKXKWKRSA-N","Interactions":"Rats fed diets containing 40% lactose for 5 days exhibited higher total liver cholesterol values than controls fed a basal sucrose diet. Lactose-supplemented diets markedly reduced the formation of coprostanol, suggesting a possible relationship between this finding and cholesterol absorption. Quantitative balance studies demonstrated the absorption of 40.4% of administered cholesterol by sucrose controls in contrast to 66.2% of the same dose by lactose-fed rats. Both 2% and 4% calcium chloride inhibited cholesterol absorption when the diet was supplemented with lactose, while as much as 4 % calcium chloride was required to produce a similar effect on a sucrose diet...","MeSH Headers":[{"Id":"M0012177","Link":"https://id.nlm.nih.gov/mesh/M0012177.html","Name":"Lactose","Ref":62},{"Id":"M0582744","Link":"https://id.nlm.nih.gov/mesh/M0582744.html","Name":"Anhydrous Lactose","Ref":64},{"Id":"DescTree","Link":"https://www.nlm.nih.gov/mesh/meshhome.html","Name":"MeSH Tree","Ref":65},{"Id":"M0020928","Link":"https://id.nlm.nih.gov/mesh/M0020928.html","Name":"Sweetening Agents","Ref":85}],"MeSH Pharmacological Classification":[{"Id":"M0020928","Link":"https://id.nlm.nih.gov/mesh/M0020928.html","Name":"Sweetening Agent","Ref":85}],"Melting Point":"433 °","MolecularFormula":"C\u003csub\u003e12\u003c/sub\u003eH\u003csub\u003e22\u003c/sub\u003eO\u003csub\u003e11\u003c/sub\u003e","MolecularWeight":"342.30 g/mol","Odor":"Odorless","Physical Description":"Lactose is a white hard crystalline powder. (NTP, 1992)","PubChemId":440995,"RefChem":"905473","RefCount":2,"RefCur":"","References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Lactose","Name":"Lactose","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q56229948","Name":"Lactose","Sub":false}]},{"Name":"DrugBank","Urls":[{"Link":"https://go.drugbank.com/DB04465","Name":"Lactose","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/440995","Name":"Lactose","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=64044-51-5","Name":"Lactose","Sub":false}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/C00243","Name":"Lactose","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID501015196","Name":"Lactose","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 440995, Lactose. 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