{"ATC Code":"D - Dermatologicals","Abbreviation":"IPA","Aliases":["Isopropyl alcohol","2-Propanol","Propan-2-ol","2-Hydroxypropane","Alkolave","Avantine","Hartosol","Dimethylcarbinol","i-Propanol","sec-Propyl alcohol"],"Biological Half-Life":"Whole body: 6 hours; whole body for acetone, a metabolite: 22 hours; [TDR, p. 781]","Boiling Point":"180.5 °","CAS":"67-63-0","ChEBI":"CHEBI:17824","ChEMBL":"CHEMBL582","ChemicalClasses":["alcohol"],"Chirality":"achiral","Classes":null,"Color/Form":"Colorless liquid","Decomposition":"When heated to decomposition it emits acrid smoke and fumes.","Density":"0.785 at 68 °F (USCG, 1999) - Less dense than water; will float g/cm\u003csup\u003e3\u003c/sup\u003e","Dosing Info":[],"DrugClasses":["depressant"],"EINECS":"200-661-7","European Community (EC) Number":"200-661-7","Flash Point":"53 °F (NTP, 1992)","HMDB ID":"HMDB0000863","HeavyAtomCount":4,"Human Drugs":"Human drug -\u003e Active ingredient (ISOPROPYL ALCOHOL)","IUPACName":"propan-2-ol","InChI":"InChI=1S/C3H8O/c1-3(2)4/h3-4H,1-2H3","InChIKey":"KFZMGEQAYNKOFK-UHFFFAOYSA-N","MeSH Pharmacological Classification":"Liquids that dissolve other substances (solutes), generally solids, without any change in chemical composition, as, water containing sugar. (Grant and Hackh\u0026apos;s Chemical Dictionary, 5th ed) (See all compounds classified as Solvents.)","Melting Point":"-127.3 °F (NTP, 1992)","MolecularFormula":"C\u003csub\u003e3\u003c/sub\u003eH\u003csub\u003e8\u003c/sub\u003eO","MolecularWeight":"60.10 g/mol","Odor":"Pleasant odor","Physical Description":"Volatile, colorless liquid with a sharp musty odor like rubbing alcohol. Flash point of 53 °F. Vapors are heavier than air and mildly irritating to the eyes, nose, and throat. Density approximately 6.5 lb / gal. Used in making cosmetics, skin and hair preparations, pharmaceuticals, perfumes, lacquer formulations, dye solutions, antifreezes, soaps, window cleaners. Sold in 70% aqueous solution as rubbing alcohol.","PrevSalts":[],"PubChemId":3776,"Record Description":["Volatile, colorless liquid with a sharp musty odor like rubbing alcohol. Flash point of 53 °F. Vapors are heavier than air and mildly irritating to the eyes, nose, and throat. Density approximately 6.5 lb / gal. Used in making cosmetics, skin and hair preparations, pharmaceuticals, perfumes, lacquer formulations, dye solutions, antifreezes, soaps, window cleaners. Sold in 70% aqueous solution as rubbing alcohol.","Propan-2-ol is a secondary alcohol that is propane in which one of the hydrogens attached to the central carbon is substituted by a hydroxy group. It has a role as a protic solvent. It is a secondary fatty alcohol and a secondary alcohol.","An isomer of 1-propanol. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.","Isopropyl Alcohol has been reported in Opuntia ficus-indica, Malus pumila, and other organisms with data available.","Isopropyl Alcohol is an isomer of propyl alcohol with antibacterial properties. Although the exact mechanism of isopropanol's disinfecting action is not known, it might kill cells by denaturing cell proteins and DNA, interfering with cellular metabolism, and dissolving cell lipo-protein membranes. Isopropanol is used in soaps and lotions as an antiseptic.","ISOPROPYL ALCOHOL is a small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 2000 and has 10 approved and 2 investigational indications.","Aluminium isopropoxide is an oxide of aluminum. It is a useful reagent in organic synthesis. Aluminum is the most abundant metal in the earth's crust and is always found combined with other elements such as oxygen, silicon, and fluorine.  (L739, L740, L761)","Isopropyl alcohol or 2-propanol is an isomer of 1-propanol. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic. Small amounts of this alcohol are produced naturally by gut microbial flora.","Isopropanol is a metabolite found in or produced by Saccharomyces cerevisiae.","An isomer of 1-PROPANOL. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.","See also: Chlorhexidine Gluconate; Isopropyl Alcohol (component of); Iodine Povacrylex; Isopropyl Alcohol (component of); AnubisMed (FDA NDC: 83021-401) (component of) ... View More ...","Propan-2-ol is a secondary alcohol that is propane in which one of the hydrogens attached to the central carbon is substituted by a hydroxy group. It has a role as a protic solvent. It is a secondary fatty alcohol and a secondary alcohol."],"References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Isopropyl alcohol","Name":"Isopropanol","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q16392","Name":"Isopropanol","Sub":false}]},{"Name":"DrugBank","Urls":[{"Link":"https://go.drugbank.com/drugs/DB02325","Name":"Isopropanol","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/3776","Name":"Isopropanol","Sub":false}]},{"Name":"ChEMBL","Urls":[{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL582","Name":"Isopropanol","Sub":false}]},{"Name":"ChEBI","Urls":[{"Link":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:17824","Name":"Isopropanol","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=67-63-0","Name":"Isopropanol","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0000863","Name":"Isopropanol","Sub":false}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/C01845","Name":"Isopropanol","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/ND2M416302","Name":"Isopropanol","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID7020762","Name":"Isopropanol","Sub":false}]}],"Reported Fatal Dose":"ACCORDING TO CLINICAL EXPERIENCE ISOPROPYL ALCOHOL IS MORE TOXIC THAN ETHYL ALCOHOL AND LESS TOXIC THAN METHYL ALCOHOL. ... ITS ACUTE POTENCY AS CENTRAL NERVOUS DEPRESSANT IS ABOUT TWICE THAT OF ETHANOL. PROBABLE LETHAL ORAL DOSE FOR ADULT IS 8 OZ (240 ML), BUT AS LITTLE AS 20 ML IN WATER CAN PRODUCE SYMPTOMS.","SMILES":"CC(C)O","Solubility":"greater than or equal to 100 mg/mL at 72 °F (NTP, 1992)","Stability/Shelf Life":"Preserve in tight containers, remove from heat.","StoreUNII":["ND2M416302"],"StructureBase64":"PHN2ZyB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciIHhtbG5zOnhsaW5rPSJodHRwOi8vd3d3LnczLm9yZy8xOTk5L3hsaW5rIiBoZWlnaHQ9IjI4LjQ3M21tIiB2ZXJzaW9uPSIxLjIiIHZpZXdCb3g9IjAgMCAzMS4wMjQgMjguNDczIiB3aWR0aD0iMzEuMDI0bW0iPgogICAgICAKICAgIDxkZXNjPkdlbmVyYXRlZCBieSB0aGUgQ2hlbWlzdHJ5IERldmVsb3BtZW50IEtpdCAoaHR0cDovL2dpdGh1Yi5jb20vY2RrKTwvZGVzYz4KICAgICAgCiAgICA8ZyBmaWxsPSIjRkYwRDBEIiBzdHJva2U9IiMwMDAwMDAiIHN0cm9rZS1saW5lY2FwPSJyb3VuZCIgc3Ryb2tlLWxpbmVqb2luPSJyb3VuZCIgc3Ryb2tlLXdpZHRoPSIuNyI+CiAgICAgICAgICAgIAogICAgICAgIDxyZWN0IGZpbGw9IiNGRkZGRkYiIGhlaWdodD0iMjkuMCIgc3Ryb2tlPSJub25lIiB3aWR0aD0iMzIuMCIgeD0iLjAiIHk9Ii4wIi8+CiAgICAgICAgICAgIAogICAgICAgIDxnIGNsYXNzPSJtb2wiIGlkPSJtb2wxIj4KICAgICAgICAgICAgICAgICAgCiAgICAgICAgICAgIDxsaW5lIGNsYXNzPSJib25kIiBpZD0ibW9sMWJuZDEiIHgxPSIxLjAzOCIgeDI9IjguNjU4IiB5MT0iMjcuNDM1IiB5Mj0iMTQuMjM2Ii8+CiAgICAgICAgICAgICAgICAgIAogICAgICAgICAgICA8bGluZSBjbGFzcz0iYm9uZCIgaWQ9Im1vbDFibmQyIiB4MT0iOC42NTgiIHgyPSIxLjAzOCIgeTE9IjE0LjIzNiIgeTI9IjEuMDM4Ii8+CiAgICAgICAgICAgICAgICAgIAogICAgICAgICAgICA8bGluZSBjbGFzcz0iYm9uZCIgaWQ9Im1vbDFibmQzIiB4MT0iOC42NTgiIHgyPSIyMC4yMzkiIHkxPSIxNC4yMzYiIHkyPSIxNC4yMzYiLz4KICAgICAgICAgICAgICAgICAgCiAgICAgICAgICAgIDxnIGNsYXNzPSJhdG9tIiBpZD0ibW9sMWF0bTQiPgogICAgICAgICAgICAgICAgICAgICAgICAKICAgICAgICAgICAgICAgIDxwYXRoIGQ9Ik0yNi4xNTcgMTQuMjMzcS4wIC43NTYgLS4yNTYgMS4zMjhxLS4yNTYgLjU2NiAtLjc1NiAuODgxcS0uNSAuMzE2IC0xLjI0NCAuMzE2cS0uNzU2IC0uMCAtMS4yNjIgLS4zMTZxLS41MDYgLS4zMTUgLS43NTYgLS44ODdxLS4yNDQgLS41NzEgLS4yNDQgLTEuMzMzcS0uMCAtLjc1MSAuMjQ0IC0xLjMxcS4yNSAtLjU2NiAuNzU2IC0uODgxcS41MDYgLS4zMTYgMS4yNzQgLS4zMTZxLjczMiAuMCAxLjIzMiAuMzE2cS41IC4zMDkgLjc1NiAuODc1cS4yNTYgLjU2NSAuMjU2IDEuMzI3ek0yMi4yOTQgMTQuMjMzcS0uMCAuOTIzIC4zODcgMS40NTlxLjM5MyAuNTMgMS4yMiAuNTNxLjg0IC0uMCAxLjIyMSAtLjUzcS4zODYgLS41MzYgLjM4NiAtMS40NTlxLjAgLS45MjggLS4zODYgLTEuNDUycS0uMzgxIC0uNTI0IC0xLjIwOSAtLjUyNHEtLjgzMyAtLjAgLTEuMjI2IC41MjRxLS4zOTMgLjUyNCAtLjM5MyAxLjQ1MnoiIHN0cm9rZT0ibm9uZSIvPgogICAgICAgICAgICAgICAgICAgICAgICAKICAgICAgICAgICAgICAgIDxwYXRoIGQ9Ik0zMC40NjQgMTYuNjg2aC0uNjJ2LTIuMjg2aC0yLjUxMnYyLjI4NmgtLjYxM3YtNC44OTloLjYxM3YyLjA3MWgyLjUxMnYtMi4wNzFoLjYydjQuODk5eiIgc3Ryb2tlPSJub25lIi8+CiAgICAgICAgICAgICAgICAgICAgICAKICAgICAgICAgICAgPC9nPgogICAgICAgICAgICAgICAgCiAgICAgICAgICAgIDxsaW5lIGNsYXNzPSJoaSIgaWQ9Im1vbDFibmQzIiBzdHJva2U9IiNGRjBEMEQiIHgxPSIyMC4yMzkiIHgyPSIxNC40NDg1IiB5MT0iMTQuMjM2IiB5Mj0iMTQuMjM2Ii8+CiAgICAgICAgPC9nPgogICAgICAgICAgCiAgICA8L2c+CiAgICAKPC9zdmc+Cg==","Taste":"Slightly bitter taste","Therapeutic Uses":"Anti-Infective Agents, Local; Solvents","Title":"Isopropanol","UNII":"ND2M416302","Wikidata":"Q16392","Wikipedia":"Isopropyl alcohol","XLogP":0.3}