{"Abbreviation":"Ile","Aliases":["2-Amino-3-methylpentanoic acid","Dl-isoleucine","443-79-8","2095501-92-9","L(+)-Isoleucine","2-amino-3-methyl-pentanoic acid","DL-2-Amino-3-methylpentanoic acid","H-DL-allo-Ile-OH","isoleucine-d10","Isoleucine, allo-"],"Boiling Point":"225.00 to 226.00 °C. @ 760.00 mm Hg","CAS":"3107-04-8","ChEBI":"CHEBI:38264","ChemicalClasses":["amino acid"],"ChiralityAminoAcid":true,"Classes":null,"Dosing Info":[],"DrugClasses":[],"European Community (EC) Number":"207-139-8","HMDB ID":"HMDB0033923","HeavyAtomCount":9,"IUPACName":"2-amino-3-methylpentanoic acid","InChI":"InChI=1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)","InChIKey":"AGPKZVBTJJNPAG-UHFFFAOYSA-N","Melting Point":"275 °C","MolecularFormula":"C\u003csub\u003e6\u003c/sub\u003eH\u003csub\u003e13\u003c/sub\u003eNO\u003csub\u003e2\u003c/sub\u003e","MolecularWeight":"131.17 g/mol","Physical Description":"Glistening solid; [Merck Index] White powder; [Sigma-Aldrich MSDS]","PubChemId":791,"Record Description":["2-amino-3-methylpentanoic acid is a branched chain amino acid that consists of 3-methylpentanoic acid bearing an amino substituent at position 2. It is an alpha-amino acid and a branched-chain amino acid.","DL-Isoleucine has been reported in Daphnia magna and Mus musculus with data available.","L-Isoleucine is one of the essential amino acids that cannot be made by the body and is known for its ability to help endurance and assist in the repair and rebuilding of muscle. This amino acid is important to body builders as it helps boost energy and helps the body recover from training.  L-Isoleucine is also classified as a branched-chain amino acid (BCAA). It helps promote muscle recovery after exercise. Isoleucine is actually broken down for energy within the muscle tissue.  It is important in hemoglobin synthesis and regulation of blood sugar and energy levels.","See also: D,L-Isoleucine (annotation moved to).","2-amino-3-methylpentanoic acid is a branched chain amino acid that consists of 3-methylpentanoic acid bearing an amino substituent at position 2. It is an alpha-amino acid and a branched-chain amino acid."],"References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Isoleucine","Name":"Isoleucine","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q110402556","Name":"Isoleucine","Sub":false},{"Link":"https://www.wikidata.org/wiki/Q27103290","Name":"D-Isoleucine","Sub":true},{"Link":"https://www.wikidata.org/wiki/Q106345669","Name":"L-Isoleucine","Sub":true}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/791","Name":"Isoleucine","Sub":false},{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/76551","Name":"D-Isoleucine","Sub":true},{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/6306","Name":"L-Isoleucine","Sub":true}]},{"Name":"ChEBI","Urls":[{"Link":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:38264","Name":"Isoleucine","Sub":false},{"Link":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:27730","Name":"D-Isoleucine","Sub":true},{"Link":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:17191","Name":"L-Isoleucine","Sub":true}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=3107-04-8","Name":"Isoleucine","Sub":false},{"Link":"https://commonchemistry.cas.org/detail?cas_rn=319-78-8","Name":"D-Isoleucine","Sub":true},{"Link":"https://commonchemistry.cas.org/detail?cas_rn=73-32-5","Name":"L-Isoleucine","Sub":true}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0033923","Name":"Isoleucine","Sub":false},{"Link":"https://hmdb.ca/metabolites/HMDB0000172","Name":"L-Isoleucine","Sub":true}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/C16434","Name":"Isoleucine","Sub":false},{"Link":"https://www.kegg.jp/entry/C06418","Name":"D-Isoleucine","Sub":true},{"Link":"https://www.kegg.jp/entry/D00065","Name":"L-Isoleucine","Sub":true}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID80901480","Name":"Isoleucine","Sub":false},{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID1046346","Name":"D-Isoleucine","Sub":true},{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID2046882","Name":"L-Isoleucine","Sub":true}]}],"SMILES":"CCC(C)C(C(=O)O)N","Solubility":"21.4 mg/mL at 25 °C","Stereoisomers":["D-Isoleucine","L-Isoleucine","DL-Isoleucine"],"StereoisomersUNII":["V87GJA0G54","5HX0BYT4E3",""],"StructureBase64":"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