{"ATC Code":"R03AL01","Abbreviation":"","Aliases":["Phenoterol","Fenoterolum","TH 1165","1-(3,5-Dihydroxyphenyl)-1-hydroxy-2-((4-hydroxyphenyl)isopropylamino)ethane","5-(1-hydroxy-2-{[1-(4-hydroxyphenyl)propan-2-yl]amino}ethyl)benzene-1,3-diol","1-(p-Hydroxyphenyl)-2-((β-hydroxy-β-(3',5'-dihydroxyphenyl))ethyl)aminopropane","3,5-Dihydroxy-α-(((p-hydroxy-α-methylphenethyl)amino)methyl)benzyl alcohol","Th 1165a","1,3-Benzenediol, 5-(1-hydroxy-2-((2-(4-hydroxyphenyl)-1-methylethyl)amino)ethyl)-","5-{1-Hydroxy-2-[2-(4-hydroxy-phenyl)-1-methyl-ethylamino]-ethyl}-benzene-1,3-diol"],"CAS":"13392-18-2","ChEBI":"CHEBI:149226","ChEMBL":"CHEMBL32800","ChemicalClasses":["amphetamine"],"Dosing Info":[],"Drug Indication":"Fenoterol is used for the treatment of asthma.","DrugClasses":[],"European Community (EC) Number":"680-817-2","HMDB ID":"HMDB0015405","HeavyAtomCount":22,"Human Drugs":"Pharmaceuticals","IUPACName":"5-[1-hydroxy-2-[1-(4-hydroxyphenyl)propan-2-ylamino]ethyl]benzene-1,3-diol","InChI":"InChI=1S/C17H21NO4/c1-11(6-12-2-4-14(19)5-3-12)18-10-17(22)13-7-15(20)9-16(21)8-13/h2-5,7-9,11,17-22H,6,10H2,1H3","InChIKey":"LSLYOANBFKQKPT-UHFFFAOYSA-N","MeSH Pharmacological Classification":"Agents that cause an increase in the expansion of a bronchus or bronchial tubes. (See all compounds classified as Bronchodilator Agents.)","Melting Point":"222-223","MolecularFormula":"C\u003csub\u003e17\u003c/sub\u003eH\u003csub\u003e21\u003c/sub\u003eNO\u003csub\u003e4\u003c/sub\u003e","MolecularWeight":"303.35 g/mol","Pharmacodynamics":"Fenoterol is a beta agonist designed to open up the airways to the lungs by decreasing bronchconstriction.","Physical Description":"Solid","PubChemId":3343,"Record Description":["Fenoterol is a member of the class resorcinols that is 5-(1-hydroxyethyl)benzene-1,3-diol in which one of the methyl hydrogens is replaced by a 1-(4-hydroxyphenyl)propan-2-amino group. A beta2-adrenergic agonist, it is used (as the hydrobromide salt) as a bronchodilator in the management of reversible airway obstruction. It has a role as a bronchodilator agent, a sympathomimetic agent, a beta-adrenergic agonist and a tocolytic agent. It is a secondary amino compound, a secondary alcohol and a member of resorcinols.","Fenoterol is an adrenergic beta-2 agonist that is used as a bronchodilator and tocolytic.","Fenoterol is a short-acting sympathomimetic agent with bronchodilator activity. Fenoterol stimulates beta-2-adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP concentrations relax bronchial smooth muscle, relieve bronchospasms, and reduce inflammatory cell mediator release, especially from mast cells.","FENOTEROL is a small molecule drug with a maximum clinical trial phase of IV (across all indications) and is indicated for airway obstruction and has 3 investigational indications. It was withdrawn in at least one region.","A synthetic adrenergic beta-2 agonist that is used as a bronchodilator and tocolytic.","Fenoterol is a member of the class resorcinols that is 5-(1-hydroxyethyl)benzene-1,3-diol in which one of the methyl hydrogens is replaced by a 1-(4-hydroxyphenyl)propan-2-amino group. A beta2-adrenergic agonist, it is used (as the hydrobromide salt) as a bronchodilator in the management of reversible airway obstruction. It has a role as a bronchodilator agent, a sympathomimetic agent, a beta-adrenergic agonist and a tocolytic agent. It is a secondary amino compound, a secondary alcohol and a member of resorcinols."],"References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Fenoterol","Name":"Fenoterol","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q420188","Name":"Fenoterol","Sub":false}]},{"Name":"DrugBank","Urls":[{"Link":"https://go.drugbank.com/drugs/DB01288","Name":"Fenoterol","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/3343","Name":"Fenoterol","Sub":false}]},{"Name":"ChemSpider","Urls":[{"Link":"https://www.chemspider.com/Chemical-Structure.3226.html","Name":"Fenoterol","Sub":false}]},{"Name":"ChEMBL","Urls":[{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL32800","Name":"Fenoterol","Sub":false}]},{"Name":"ChEBI","Urls":[{"Link":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:149226","Name":"Fenoterol","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=13392-18-2","Name":"Fenoterol","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0015405","Name":"Fenoterol","Sub":false}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/D01428","Name":"Fenoterol","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID4023046","Name":"Fenoterol","Sub":false}]}],"SMILES":"CC(CC1=CC=C(C=C1)O)NCC(C2=CC(=CC(=C2)O)O)O","Solubility":"1.62e-01 g/L","StructureBase64":"<svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" height="67.141mm" version="1.2" viewBox="0 0 172.636 67.141" width="172.636mm">
      
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