{"ATC Code":"P - Antiparasitic products, insecticides and repellents","Abbreviation":"","Aliases":["Emetin","Cephaeline methyl ether","Methyl cephaeline","6',7',10,11-Tetramethoxyemetan","(-)-Emetine","Cephaline-O-methyl ether","Emetinum","Emetan, 6',7',10,11-tetramethoxy-","Tcmdc-125531","GNF-PF-196"],"CAS":"483-18-1","ChEBI":"CHEBI:4781","ChEMBL":"CHEMBL50588","ChemicalClasses":["piperidine"],"Chirality":"absolute","Color/Form":"WHITE AMORPHOUS POWDER","Decomposition":"When heated to decomposition it emits highly toxic fumes of /nitrogen oxides/.","Dosing Info":[],"Drug Warnings":"Patients ... should remain sedentary, they require close medical supervision (including electrocardiographic monitoring).","DrugClasses":[],"EINECS":"207-592-1","European Community (EC) Number":"207-592-1","FullSalts":["Emetine hydrochloride","Emetine sulfate"],"HeavyAtomCount":35,"IUPACName":"(2S,3R,11bS)-2-[[(1R)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl]-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizine","InChI":"InChI=1S/C29H40N2O4/c1-6-18-17-31-10-8-20-14-27(33-3)29(35-5)16-23(20)25(31)12-21(18)11-24-22-15-28(34-4)26(32-2)13-19(22)7-9-30-24/h13-16,18,21,24-25,30H,6-12,17H2,1-5H3/t18-,21-,24+,25-/m0/s1","InChIKey":"AUVVAXYIELKVAI-CKBKHPSWSA-N","MeSH Pharmacological Classification":"Agents which are destructive to amebae, especially the parasitic species causing AMEBIASIS in man and animal. (See all compounds classified as Amebicides.)","Melting Point":"74 °C","MolecularFormula":"C\u003csub\u003e29\u003c/sub\u003eH\u003csub\u003e40\u003c/sub\u003eN\u003csub\u003e2\u003c/sub\u003eO\u003csub\u003e4\u003c/sub\u003e","MolecularWeight":"480.6 g/mol","Opticalactivity":"UNSPECIFIED","PrevSalts":["hydrochloride","sulfate"],"PubChemId":10219,"Record Description":["Emetine is a pyridoisoquinoline comprising emetam having methoxy substituents at the 6'-, 7'-, 10- and 11-positions. It is an antiprotozoal agent and emetic. It inhibits SARS-CoV2, Zika and Ebola virus replication and displays antimalarial, antineoplastic and antiamoebic properties. It has a role as an antiprotozoal drug, a plant metabolite, an antiviral agent, an emetic, a protein synthesis inhibitor, an antimalarial, an antineoplastic agent, an autophagy inhibitor, an antiinfective agent, an expectorant, an anticoronaviral agent and an antiamoebic agent. It is a pyridoisoquinoline and an isoquinoline alkaloid. It is functionally related to a cephaeline. It is a conjugate base of an emetine(2+). It derives from a hydride of an emetan.","Emetine has been reported in Alangium salviifolium, Hedera helix, and other organisms with data available.","Emetine Hydrochloride is the chloride salt of a white crystalline bitter alkaloid isolated from the root of the plant Psychotria Ipecacuanha (ipecac root) and other plants with antiemetic and anthelminthic properties.  Emetine inhibits protein synthesis in eukaryotic (but not prokaryotic) cells by irreversibly blocking ribosome movement along the mRNA strand and inhibits DNA replication in the early S phase of the cell cycle. (NCI04)","EMETINE is a small molecule drug with a maximum clinical trial phase of II (across all indications) and has 2 investigational indications.","The principal alkaloid of ipecac, from the ground roots of Uragoga (or Cephaelis) ipecacuanha or U. acuminata, of the Rubiaceae. It is used as an amebicide in many different preparations and may cause serious cardiac, hepatic, or renal damage and violent diarrhea and vomiting. Emetine inhibits protein synthesis in EUKARYOTIC CELLS but not PROKARYOTIC CELLS.","Emetine is a pyridoisoquinoline comprising emetam having methoxy substituents at the 6'-, 7'-, 10- and 11-positions. It is an antiprotozoal agent and emetic. It inhibits SARS-CoV2, Zika and Ebola virus replication and displays antimalarial, antineoplastic and antiamoebic properties. It has a role as an antiprotozoal drug, a plant metabolite, an antiviral agent, an emetic, a protein synthesis inhibitor, an antimalarial, an antineoplastic agent, an autophagy inhibitor, an antiinfective agent, an expectorant, an anticoronaviral agent and an antiamoebic agent. It is a pyridoisoquinoline and an isoquinoline alkaloid. It is functionally related to a cephaeline. It is a conjugate base of an emetine(2+). It derives from a hydride of an emetan."],"References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Emetine","Name":"Emetine","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q3050386","Name":"Emetine","Sub":false}]},{"Name":"DrugBank","Urls":[{"Link":"https://go.drugbank.com/drugs/DB13393","Name":"Emetine","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/10219","Name":"Emetine","Sub":false}]},{"Name":"ChemSpider","Urls":[{"Link":"https://www.chemspider.com/Chemical-Structure.9802.html","Name":"Emetine","Sub":false}]},{"Name":"ChEMBL","Urls":[{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL50588","Name":"Emetine","Sub":false}]},{"Name":"ChEBI","Urls":[{"Link":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:4781","Name":"Emetine","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=483-18-1","Name":"Emetine","Sub":false}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/C09421","Name":"Emetine","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/X8D5EPO80M","Name":"Emetine","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID5022980","Name":"Emetine","Sub":false}]}],"SMILES":"CC[C@H]1CN2CCC3=CC(=C(C=C3[C@@H]2C[C@@H]1C[C@@H]4C5=CC(=C(C=C5CCN4)OC)OC)OC)OC","Salts":["hydrochloride","sulfate"],"SaltsAcidCount":[2,1],"SaltsAmineCount":[1,1],"SaltsUNII":["U52OG12P96","C75KA24QYC"],"Solubility":"MODERATELY SOL IN DILUTE AMMONIUM HYDROXIDE; SOL IN ETHER, ALCOHOL, ACETONE; SLIGHTLY SOL IN CHLOROFORM, BENZENE; INSOL IN GLACIAL ACETIC ACID; SOL IN 80% ACETIC ACID","Stability/Shelf Life":"TURNS YELLOW ON EXPOSURE TO LIGHT AND HEAT.","StoreUNII":["X8D5EPO80M"],"StructureBase64":"<svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" height="120.887mm" version="1.2" viewBox="0 0 162.0 120.887" width="162.0mm">
      
    <desc>Generated by the Chemistry Development Kit (http://github.com/cdk)</desc>
      
    <g fill="#FF0D0D" stroke="#000000" stroke-linecap="round" stroke-linejoin="round" stroke-width=".7">
            
        <rect fill="#FFFFFF" height="121.0" stroke="none" width="163.0" x=".0" y=".0"/>
            
        <g class="mol" id="mol1">
                  
            <line class="bond" id="mol1bnd1" x1="39.045" x2="46.662" y1="14.237" y2="27.437"/>
                  
            <path class="bond" d="M61.901 27.791v-.7l-16.943 -1.904l1.298 2.25l1.137 1.97z" fill="#000000" id="mol1bnd2" stroke="none"/>
                  
            <line class="bond" id="mol1bnd3" x1="61.902" x2="69.524" y1="27.441" y2="14.246"/>
                  
            <line class="bond" id="mol1bnd4" x1="69.524" x2="81.423" y1="14.246" y2="14.246"/>
                  
            <line class="bond" id="mol1bnd5" x1="86.877" x2="92.384" y1="10.584" y2="1.038"/>
                  
            <line class="bond" id="mol1bnd6" x1="92.384" x2="107.624" y1="1.038" y2="1.038"/>
                  
            <line class="bond" id="mol1bnd7" x1="107.624" x2="115.244" y1="1.038" y2="14.246"/>
                  
            <g class="bond" id="mol1bnd8">
                        
                <line x1="130.483" x2="115.244" y1="14.246" y2="14.246"/>
                        
                <line x1="129.076" x2="116.652" y1="16.684" y2="16.685"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd9" x1="130.483" x2="138.106" y1="14.246" y2="27.441"/>
                  
            <g class="bond" id="mol1bnd10">
                        
                <line x1="130.491" x2="138.106" y1="40.641" y2="27.441"/>
                        
                <line x1="129.082" x2="135.29" y1="38.203" y2="27.442"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd11" x1="130.491" x2="115.252" y1="40.641" y2="40.647"/>
                  
            <g class="bond" id="mol1bnd12">
                        
                <line x1="107.624" x2="115.252" y1="27.454" y2="40.647"/>
                        
                <line x1="110.44" x2="116.658" y1="27.453" y2="38.208"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd13" x1="115.244" x2="107.624" y1="14.246" y2="27.454"/>
                  
            <line class="bond" id="mol1bnd14" x1="107.624" x2="92.384" y1="27.454" y2="27.454"/>
                  
            <g class="bond" id="mol1bnd15">
                        
                <line stroke="#000000" x1="92.08" x2="92.687" y1="27.629" y2="27.279"/>
                        
                <line stroke="#3050F8" x1="90.775" x2="91.815" y1="25.867" y2="25.267"/>
                        
                <line stroke="#3050F8" x1="89.47" x2="90.943" y1="24.105" y2="23.256"/>
                        
                <line stroke="#3050F8" x1="88.165" x2="90.071" y1="22.343" y2="21.244"/>
                        
                <line stroke="#3050F8" x1="86.86" x2="89.199" y1="20.581" y2="19.232"/>
                        
                <line stroke="#3050F8" x1="85.555" x2="88.327" y1="18.819" y2="17.22"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd16" x1="92.384" x2="84.755" y1="27.454" y2="40.647"/>
                  
            <line class="bond" id="mol1bnd17" x1="84.755" x2="69.517" y1="40.647" y2="40.641"/>
                  
            <line class="bond" id="mol1bnd18" x1="61.902" x2="69.517" y1="27.441" y2="40.641"/>
                  
            <g class="bond" id="mol1bnd19">
                        
                <line x1="69.82" x2="69.214" y1="40.816" y2="40.466"/>
                        
                <line x1="68.947" x2="67.908" y1="42.826" y2="42.226"/>
                        
                <line x1="68.074" x2="66.602" y1="44.836" y2="43.986"/>
                        
                <line x1="67.201" x2="65.296" y1="46.847" y2="45.746"/>
                        
                <line x1="66.329" x2="63.991" y1="48.857" y2="47.506"/>
                        
                <line x1="65.456" x2="62.685" y1="50.867" y2="49.266"/>
                        
                <line x1="64.583" x2="61.379" y1="52.877" y2="51.026"/>
                        
                <line x1="63.71" x2="60.073" y1="54.887" y2="52.786"/>
                      
            </g>
                  
            <g class="bond" id="mol1bnd20">
                        
                <line x1="46.652" x2="46.652" y1="53.481" y2="54.181"/>
                        
                <line x1="48.829" x2="48.829" y1="53.232" y2="54.432"/>
                        
                <line x1="51.006" x2="51.006" y1="52.982" y2="54.683"/>
                        
                <line x1="53.184" x2="53.183" y1="52.733" y2="54.933"/>
                        
                <line x1="55.361" x2="55.36" y1="52.484" y2="55.184"/>
                        
                <line x1="57.538" x2="57.537" y1="52.235" y2="55.435"/>
                        
                <line x1="59.715" x2="59.714" y1="51.985" y2="55.686"/>
                        
                <line x1="61.893" x2="61.891" y1="51.736" y2="55.937"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd21" x1="46.652" x2="39.027" y1="53.831" y2="67.036"/>
                  
            <g class="bond" id="mol1bnd22">
                        
                <line x1="46.642" x2="39.027" y1="80.247" y2="67.036"/>
                        
                <line x1="43.827" x2="37.618" y1="80.246" y2="69.474"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd23" x1="46.642" x2="39.017" y1="80.247" y2="93.452"/>
                  
            <g class="bond" id="mol1bnd24">
                        
                <line x1="23.777" x2="39.017" y1="93.446" y2="93.452"/>
                        
                <line x1="25.186" x2="37.61" y1="91.008" y2="91.013"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd25" x1="23.777" x2="16.162" y1="93.446" y2="80.236"/>
                  
            <g class="bond" id="mol1bnd26">
                        
                <line x1="23.787" x2="16.162" y1="67.03" y2="80.236"/>
                        
                <line x1="25.194" x2="18.977" y1="69.469" y2="80.237"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd27" x1="39.027" x2="23.787" y1="67.036" y2="67.03"/>
                  
            <line class="bond" id="mol1bnd28" x1="23.787" x2="16.172" y1="67.03" y2="53.82"/>
                  
            <line class="bond" id="mol1bnd29" x1="16.172" x2="23.797" y1="53.82" y2="40.614"/>
                  
            <line class="bond" id="mol1bnd30" x1="23.797" x2="35.696" y1="40.614" y2="40.619"/>
                  
            <line class="bond" id="mol1bnd31" x1="46.652" x2="41.148" y1="53.831" y2="44.283"/>
                  
            <line class="bond" id="mol1bnd32" x1="23.777" x2="18.12" y1="93.446" y2="103.233"/>
                  
            <line class="bond" id="mol1bnd33" x1="12.491" x2=".91" y1="106.639" y2="106.633"/>
                  
            <line class="bond" id="mol1bnd34" x1="39.017" x2="44.665" y1="93.452" y2="103.24"/>
                  
            <line class="bond" id="mol1bnd35" x1="44.664" x2="39.012" y1="110.063" y2="119.848"/>
                  
            <line class="bond" id="mol1bnd36" x1="130.491" x2="136.145" y1="40.641" y2="50.426"/>
                  
            <line class="bond" id="mol1bnd37" x1="141.775" x2="153.355" y1="53.835" y2="53.831"/>
                  
            <line class="bond" id="mol1bnd38" x1="138.106" x2="149.686" y1="27.441" y2="27.438"/>
                  
            <line class="bond" id="mol1bnd39" x1="155.313" x2="160.962" y1="24.028" y2="14.237"/>
                  
            <path class="atom" d="M86.704 16.696h-.72l-2.619 -4.066h-.03q.012 .238 .03 .595q.023 .357 .023 .732v2.739h-.565v-4.9h.714l2.608 4.054h.03q-.006 -.107 -.018 -.327q-.012 -.22 -.024 -.476q-.006 -.262 -.006 -.482v-2.769h.577v4.9z" fill="#3050F8" id="mol1atm5" stroke="none"/>
                  
            <g class="atom" id="mol1atm27">
                        
                <path d="M40.977 43.07h-.72l-2.619 -4.066h-.03q.012 .238 .03 .595q.024 .357 .024 .732v2.739h-.566v-4.9h.714l2.608 4.054h.03q-.006 -.107 -.018 -.327q-.012 -.22 -.024 -.476q-.006 -.262 -.006 -.483v-2.768h.577v4.9z" fill="#3050F8" stroke="none"/>
                        
                <path d="M45.284 43.07h-.62v-2.286h-2.512v2.286h-.613v-4.9h.613v2.072h2.512v-2.072h.62v4.9z" fill="#3050F8" stroke="none"/>
                      
            </g>
                  
            <path class="atom" d="M18.409 106.638q.0 .756 -.256 1.327q-.256 .566 -.756 .881q-.5 .316 -1.244 .316q-.756 -.0 -1.262 -.316q-.506 -.315 -.756 -.887q-.244 -.571 -.244 -1.333q.0 -.75 .244 -1.31q.25 -.566 .756 -.881q.506 -.316 1.274 -.316q.732 .0 1.232 .316q.5 .309 .756 .875q.256 .566 .256 1.328zM14.546 106.638q-.0 .922 .387 1.458q.393 .53 1.22 .53q.84 -.0 1.221 -.53q.387 -.536 .387 -1.458q-.0 -.929 -.387 -1.453q-.381 -.524 -1.209 -.524q-.833 .0 -1.226 .524q-.393 .524 -.393 1.453z" id="mol1atm28" stroke="none"/>
                  
            <path class="atom" d="M48.894 106.649q-.0 .756 -.256 1.327q-.256 .566 -.756 .881q-.5 .316 -1.245 .316q-.756 -.0 -1.262 -.316q-.506 -.315 -.756 -.887q-.244 -.571 -.244 -1.333q.0 -.75 .244 -1.31q.25 -.565 .756 -.881q.506 -.315 1.274 -.315q.733 -.0 1.233 .315q.5 .31 .756 .875q.256 .566 .256 1.328zM45.03 106.649q.0 .923 .387 1.458q.393 .53 1.22 .53q.84 .0 1.221 -.53q.387 -.535 .387 -1.458q-.0 -.929 -.387 -1.453q-.381 -.524 -1.209 -.524q-.833 .0 -1.226 .524q-.393 .524 -.393 1.453z" id="mol1atm30" stroke="none"/>
                  
            <path class="atom" d="M140.375 53.833q-.0 .756 -.256 1.328q-.256 .566 -.756 .881q-.5 .316 -1.245 .316q-.756 -.0 -1.262 -.316q-.506 -.315 -.756 -.887q-.244 -.571 -.244 -1.333q.0 -.751 .244 -1.31q.25 -.566 .756 -.881q.506 -.316 1.274 -.316q.733 .0 1.233 .316q.5 .309 .756 .875q.256 .565 .256 1.327zM136.511 53.833q.0 .923 .387 1.459q.393 .53 1.22 .53q.84 -.0 1.221 -.53q.387 -.536 .387 -1.459q-.0 -.928 -.387 -1.452q-.381 -.524 -1.209 -.524q-.833 -.0 -1.226 .524q-.393 .524 -.393 1.452z" id="mol1atm32" stroke="none"/>
                  
            <path class="atom" d="M155.605 27.434q-.0 .756 -.256 1.328q-.256 .565 -.756 .881q-.5 .315 -1.244 .315q-.756 .0 -1.262 -.315q-.506 -.316 -.756 -.887q-.244 -.572 -.244 -1.334q-.0 -.75 .244 -1.309q.25 -.566 .756 -.881q.506 -.316 1.274 -.316q.732 .0 1.232 .316q.5 .309 .756 .875q.256 .565 .256 1.327zM151.741 27.434q.0 .923 .387 1.459q.393 .53 1.221 .53q.839 -.0 1.22 -.53q.387 -.536 .387 -1.459q.0 -.928 -.387 -1.452q-.381 -.524 -1.208 -.524q-.834 -.0 -1.227 .524q-.393 .524 -.393 1.452z" id="mol1atm34" stroke="none"/>
                
            <line class="hi" id="mol1bnd4" stroke="#3050F8" x1="81.423" x2="75.4735" y1="14.246" y2="14.246"/>
            <line class="hi" id="mol1bnd5" stroke="#3050F8" x1="86.877" x2="89.6305" y1="10.584" y2="5.811"/>
            <line class="hi" id="mol1bnd30" stroke="#3050F8" x1="35.696" x2="29.746499999999997" y1="40.619" y2="40.6165"/>
            <line class="hi" id="mol1bnd31" stroke="#3050F8" x1="41.148" x2="43.900000000000006" y1="44.283" y2="49.057"/>
            <line class="hi" id="mol1bnd31" stroke="#3050F8" x1="41.65476018966836" x2="43.900000000000006" y1="45.16209634646683" y2="49.057"/>
            <line class="hi" id="mol1bnd32" stroke="#FF0D0D" x1="18.12" x2="20.948500000000003" y1="103.233" y2="98.3395"/>
            <line class="hi" id="mol1bnd33" stroke="#FF0D0D" x1="12.491" x2="6.7005" y1="106.639" y2="106.636"/>
            <line class="hi" id="mol1bnd34" stroke="#FF0D0D" x1="44.665" x2="41.841" y1="103.24" y2="98.346"/>
            <line class="hi" id="mol1bnd35" stroke="#FF0D0D" x1="44.664" x2="41.838" y1="110.063" y2="114.9555"/>
            <line class="hi" id="mol1bnd36" stroke="#FF0D0D" x1="136.145" x2="133.318" y1="50.426" y2="45.533500000000004"/>
            <line class="hi" id="mol1bnd37" stroke="#FF0D0D" x1="141.775" x2="147.565" y1="53.835" y2="53.833"/>
            <line class="hi" id="mol1bnd38" stroke="#FF0D0D" x1="149.686" x2="143.89600000000002" y1="27.438" y2="27.4395"/>
            <line class="hi" id="mol1bnd39" stroke="#FF0D0D" x1="155.313" x2="158.1375" y1="24.028" y2="19.1325"/>
        </g>
          
    </g>
    
</svg>
","Taste":"Very bitter taste","Therapeutic Uses":"Amebicides; Antinematodal Agents; Protein Synthesis Inhibitors","Title":"Emetine","UNII":"X8D5EPO80M","Wikidata":"Q3050386","XLogP":4.7,"pH":"STRONG ALKALINE REACTION"}