{"ATC Code":"A03FA03","Abbreviation":"","Aliases":["Motilium","Domperidona","Domperidonum","Nauzelin","R 33,812","R-33812","KW 5338","KW-5338","4-(5-Chloro-2-oxo-1-benzimidazolinyl)-1-[3-(2-oxobenzimidazolinyl)propyl]piperidine","5-Chloro-1-(1-(3-(2-oxo-1-benzimidazolinyl)propyl)-4-piperidyl)-2-benzimidazolinone"],"Biological Half-Life":"7 hours","CAS":"57808-66-9","ChEBI":"CHEBI:31515","ChEMBL":"CHEMBL219916","ChemicalClasses":["benzimidazole"],"Chirality":"achiral","Dosing Info":[],"Drug Classes":"Breast Feeding; Lactation; Milk, Human; Antiemetics; Dopamine Antagonists; Galactogogues; Gastrointestinal Agents","Drug Indication":"For management of dyspepsia, heartburn, epigastric pain, nausea, and vomiting.","DrugClasses":[],"EINECS":"260-968-7","European Community (EC) Number":"260-968-7","Human Drugs":"Breast Feeding; Lactation; Milk, Human; Antiemetics; Dopamine Antagonists; Galactogogues; Gastrointestinal Agents","IUPACName":"6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one","Impurities":["5-chloro-1-(4-piperidinyl)-2-benzimidazolinone","4-(5-chloro-2-oxo-2,3-dihydro-1h-benzimidazol-1-yl)-1-formylpiperidine","1,3-bis(3-(4-(5-chloro-2-oxo-3h-benzimidazol-1-yl)piperidin-1-yl)propyl)benzimidazol-2-one","1-(3-(4-(5-chloro-2-oxo-3h-benzimidazol-1-yl)piperidin-1-yl)propyl)-3-(3-(2-oxo-3h-benzimidazol-1-yl)propyl)benzimidazol-2-one","5-chloro-3-(3-(2-oxo-2,3-dihydro-1h-benzimidazol-1-yl)propyl)-1-(1-(3-(2-oxo-2,3-dihydro-1h-benzimidazol-1-yl) propyl) piperidin-4-yl)- 1,3-dihydro-2h-benzimidazol-2-one"],"InChI":"InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30)","InChIKey":"FGXWKSZFVQUSTL-UHFFFAOYSA-N","MeSH Pharmacological Classification":"Drugs used to prevent NAUSEA or VOMITING. (See all compounds classified as Antiemetics.)","Melting Point":"242.5 °C","MolecularFormula":"C\u003csub\u003e22\u003c/sub\u003eH\u003csub\u003e24\u003c/sub\u003eClN\u003csub\u003e5\u003c/sub\u003eO\u003csub\u003e2\u003c/sub\u003e","MolecularWeight":"425.9 g/mol","Pharmacodynamics":"Domperidone is a specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.","Physical Description":"Solid","PubChemId":3151,"Record Description":["Domperidone is 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations. It has a role as an antiemetic and a dopaminergic antagonist. It is a member of benzimidazoles and a heteroarylpiperidine.","A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.","Domperidone is a peripheral-specific antagonist of the dopamine receptor D2 (D2R), with antiemetic, gastrokinetic and galactagogue activities. Following administration, domperidone binds to D2R expressed by peripheral neurons; this inhibits dopamine binding and D2R-mediated signaling. Inhibition of peripheral D2R signaling prevents or relieves various gastrointestinal (GI) symptoms, such as nausea and vomiting, and may help relief reflux and symptoms of a variety of other upper GI disorders.","DOMPERIDONE is a small molecule drug with a maximum clinical trial phase of IV (across all indications) and is indicated for gastrointestinal disease and has 9 investigational indications.","A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.","See also: Domperidone Maleate (is active moiety of) ... View More ...","Domperidone is 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations. It has a role as an antiemetic and a dopaminergic antagonist. It is a member of benzimidazoles and a heteroarylpiperidine.","LiverTox|Gastroinestinal|Prokinetic agent|Antidopaminergic"],"References":[{"name":"Wikipedia","url":"https://en.wikipedia.org/wiki/Domperidone"},{"name":"Wikidata","url":"https://www.wikidata.org/wiki/Q424238"},{"name":"DrugBank","url":"https://go.drugbank.com/drugs/DB01184"},{"name":"PubChem","url":"https://pubchem.ncbi.nlm.nih.gov/compound/3151"},{"name":"ChemSpider","url":"https://www.chemspider.com/Chemical-Structure.3039.html"},{"name":"ChEMBL","url":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL219916"},{"name":"ChEBI","url":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:31515"},{"name":"Common Chemistry","url":"https://commonchemistry.cas.org/detail?cas_rn=57808-66-9"},{"name":"HMDB","url":"https://hmdb.ca/metabolites/HMDB0015315"},{"name":"KEGG","url":"https://www.kegg.jp/entry/D01745"},{"name":"UNII","url":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/5587267Z69"},{"name":"EPA DSSTox","url":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID1045116"}],"SMILES":"C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCN4C5=CC=CC=C5NC4=O","Salts":["maleate","acetate"],"Solubility":"50.4 [ug/mL] (The mean of the results at pH 7.4)","StructureBase64":"<svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" height="153.059mm" version="1.2" viewBox="0 0 144.353 153.059" width="144.353mm">
      
    <desc>Generated by the Chemistry Development Kit (http://github.com/cdk)</desc>
      
    <g fill="#3050F8" stroke="#000000" stroke-linecap="round" stroke-linejoin="round" stroke-width=".7">
            
        <rect fill="#FFFFFF" height="154.0" stroke="none" width="145.0" x=".0" y=".0"/>
            
        <g class="mol" id="mol1">
                  
            <line class="bond" id="mol1bnd1" x1="54.038" x2="58.765" y1="58.887" y2="73.376"/>
                  
            <line class="bond" id="mol1bnd2" x1="58.765" x2="70.374" y1="73.376" y2="75.825"/>
                  
            <line class="bond" id="mol1bnd3" x1="76.562" x2="83.878" y1="73.322" y2="65.182"/>
                  
            <line class="bond" id="mol1bnd4" x1="83.878" x2="79.151" y1="65.182" y2="50.694"/>
                  
            <line class="bond" id="mol1bnd5" x1="79.151" x2="64.231" y1="50.694" y2="47.546"/>
                  
            <line class="bond" id="mol1bnd6" x1="54.038" x2="64.231" y1="58.887" y2="47.546"/>
                  
            <line class="bond" id="mol1bnd7" x1="64.231" x2="60.737" y1="47.546" y2="36.839"/>
                  
            <line class="bond" id="mol1bnd8" x1="56.23" x2="44.975" y1="32.005" y2="28.384"/>
                  
            <g class="bond" id="mol1bnd9">
                        
                <line x1="44.975" x2="44.975" y1="28.384" y2="13.144"/>
                        
                <line x1="42.536" x2="42.536" y1="26.976" y2="14.553"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd10" x1="44.975" x2="31.767" y1="13.144" y2="5.524"/>
                  
            <g class="bond" id="mol1bnd11">
                        
                <line x1="31.767" x2="18.559" y1="5.524" y2="13.144"/>
                        
                <line x1="31.767" x2="20.997" y1="8.34" y2="14.553"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd12" x1="18.559" x2="18.559" y1="13.144" y2="28.384"/>
                  
            <g class="bond" id="mol1bnd13">
                        
                <line x1="18.559" x2="31.767" y1="28.384" y2="36.004"/>
                        
                <line x1="20.997" x2="31.767" y1="26.976" y2="33.189"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd14" x1="44.975" x2="31.767" y1="28.384" y2="36.004"/>
                  
            <line class="bond" id="mol1bnd15" x1="18.559" x2="6.875" y1="13.144" y2="6.396"/>
                  
            <line class="bond" id="mol1bnd16" x1="44.975" x2="56.23" y1="13.144" y2="9.524"/>
                  
            <line class="bond" id="mol1bnd17" x1="62.109" x2="68.444" y1="12.053" y2="20.764"/>
                  
            <line class="bond" id="mol1bnd18" x1="62.109" x2="68.444" y1="29.476" y2="20.764"/>
                  
            <g class="bond" id="mol1bnd19">
                        
                <line x1="67.557" x2="80.025" y1="19.545" y2="19.545"/>
                        
                <line x1="67.557" x2="80.025" y1="21.984" y2="21.984"/>
                      
                <line class="hi" stroke="#FF0D0D" x1="80.025" x2="73.791" y1="19.545" y2="19.545"/>
                <line class="hi" stroke="#FF0D0D" x1="80.025" x2="73.791" y1="21.984" y2="21.984"/>
            </g>
                  
            <line class="bond" id="mol1bnd20" x1="74.919" x2="78.412" y1="80.304" y2="91.011"/>
                  
            <line class="bond" id="mol1bnd21" x1="78.412" x2="93.323" y1="91.011" y2="94.161"/>
                  
            <line class="bond" id="mol1bnd22" x1="93.323" x2="98.05" y1="94.161" y2="108.65"/>
                  
            <line class="bond" id="mol1bnd23" x1="98.05" x2="109.651" y1="108.65" y2="111.101"/>
                  
            <line class="bond" id="mol1bnd24" x1="114.619" x2="119.162" y1="115.529" y2="125.746"/>
                  
            <g class="bond" id="mol1bnd25">
                        
                <line x1="119.162" x2="112.999" y1="125.746" y2="139.693"/>
                        
                <line x1="120.823" x2="115.798" y1="128.019" y2="139.392"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd26" x1="112.999" x2="121.988" y1="139.693" y2="152.01"/>
                  
            <g class="bond" id="mol1bnd27">
                        
                <line x1="121.988" x2="137.14" y1="152.01" y2="150.38"/>
                        
                <line x1="123.127" x2="135.479" y1="149.435" y2="148.106"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd28" x1="137.14" x2="143.304" y1="150.38" y2="136.432"/>
                  
            <g class="bond" id="mol1bnd29">
                        
                <line x1="143.304" x2="134.315" y1="136.432" y2="124.115"/>
                        
                <line x1="140.505" x2="133.175" y1="136.734" y2="126.69"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd30" x1="119.162" x2="134.315" y1="125.746" y2="124.115"/>
                  
            <line class="bond" id="mol1bnd31" x1="134.315" x2="136.617" y1="124.115" y2="112.991"/>
                  
            <line class="bond" id="mol1bnd32" x1="134.253" x2="124.228" y1="107.357" y2="101.595"/>
                  
            <line class="bond" id="mol1bnd33" x1="115.94" x2="124.228" y1="109.102" y2="101.595"/>
                  
            <g class="bond" id="mol1bnd34">
                        
                <line x1="123.11" x2="121.806" y1="102.608" y2="90.487"/>
                        
                <line x1="125.535" x2="124.231" y1="102.347" y2="90.226"/>
                      
                <line class="hi" stroke="#FF0D0D" x1="121.806" x2="122.458" y1="90.487" y2="96.5475"/>
                <line class="hi" stroke="#FF0D0D" x1="124.231" x2="124.883" y1="90.226" y2="96.28649999999999"/>
            </g>
                  
            <path class="atom" d="M75.626 78.973h-.721l-2.619 -4.066h-.03q.012 .238 .03 .595q.024 .357 .024 .732v2.739h-.566v-4.9h.715l2.607 4.054h.03q-.006 -.107 -.018 -.327q-.012 -.22 -.024 -.476q-.006 -.262 -.006 -.483v-2.768h.578v4.9z" id="mol1atm3" stroke="none"/>
                  
            <path class="atom" d="M61.444 35.508h-.72l-2.62 -4.066h-.029q.012 .238 .029 .595q.024 .357 .024 .732v2.739h-.565v-4.9h.714l2.607 4.054h.03q-.006 -.107 -.018 -.327q-.012 -.22 -.023 -.476q-.006 -.262 -.006 -.482v-2.769h.577v4.9z" id="mol1atm7" stroke="none"/>
                  
            <path class="atom" d="M2.906 3.707q-.786 -.0 -1.239 .529q-.452 .524 -.452 1.447q-.0 .911 .417 1.447q.422 .529 1.268 .529q.321 .0 .607 -.053q.292 -.06 .565 -.143v.536q-.273 .101 -.565 .149q-.292 .053 -.697 .053q-.744 .0 -1.25 -.309q-.5 -.31 -.75 -.875q-.25 -.572 -.25 -1.34q.0 -.744 .268 -1.31q.274 -.565 .804 -.881q.529 -.321 1.279 -.321q.78 -.0 1.352 .286l-.244 .523q-.226 -.101 -.506 -.184q-.274 -.083 -.607 -.083zM5.662 8.13h-.601v-5.215h.601v5.215z" fill="#1FF01F" id="mol1atm14" stroke="none"/>
                  
            <g class="atom" id="mol1atm15">
                        
                <path d="M61.444 10.921h-.72l-2.62 -4.066h-.029q.012 .238 .029 .595q.024 .357 .024 .732v2.739h-.565v-4.9h.714l2.607 4.054h.03q-.006 -.107 -.018 -.327q-.012 -.221 -.023 -.476q-.006 -.262 -.006 -.483v-2.768h.577v4.9z" stroke="none"/>
                        
                <path d="M61.307 5.459h-.619v-2.286h-2.512v2.286h-.613v-4.899h.613v2.072h2.512v-2.072h.619v4.899z" stroke="none"/>
                      
            </g>
                  
            <path class="atom" d="M85.943 20.761q.0 .756 -.256 1.328q-.256 .566 -.756 .881q-.5 .316 -1.244 .316q-.756 -.0 -1.262 -.316q-.506 -.315 -.756 -.887q-.244 -.571 -.244 -1.333q-.0 -.751 .244 -1.31q.25 -.566 .756 -.881q.506 -.316 1.274 -.316q.732 .0 1.232 .316q.5 .309 .756 .875q.256 .565 .256 1.327zM82.08 20.761q-.0 .923 .387 1.459q.393 .53 1.22 .53q.84 -.0 1.221 -.53q.386 -.536 .386 -1.459q.0 -.928 -.386 -1.452q-.381 -.524 -1.209 -.524q-.833 -.0 -1.226 .524q-.393 .524 -.393 1.452z" fill="#FF0D0D" id="mol1atm17" stroke="none"/>
                  
            <path class="atom" d="M114.902 114.25h-.72l-2.62 -4.066h-.03q.012 .238 .03 .595q.024 .357 .024 .732v2.739h-.566v-4.9h.715l2.607 4.054h.03q-.006 -.107 -.018 -.327q-.012 -.22 -.024 -.476q-.006 -.262 -.006 -.482v-2.769h.578v4.9z" id="mol1atm21" stroke="none"/>
                  
            <g class="atom" id="mol1atm28">
                        
                <path d="M139.348 111.62h-.72l-2.62 -4.066h-.029q.011 .238 .029 .595q.024 .357 .024 .732v2.739h-.565v-4.9h.714l2.607 4.054h.03q-.006 -.107 -.018 -.327q-.012 -.22 -.024 -.476q-.005 -.262 -.005 -.483v-2.768h.577v4.9z" stroke="none"/>
                        
                <path d="M143.654 111.62h-.619v-2.286h-2.512v2.286h-.613v-4.9h.613v2.072h2.512v-2.072h.619v4.9z" stroke="none"/>
                      
            </g>
                  
            <path class="atom" d="M124.857 86.44q-.0 .756 -.256 1.328q-.256 .565 -.756 .881q-.5 .315 -1.244 .315q-.757 .0 -1.263 -.315q-.506 -.316 -.756 -.887q-.244 -.572 -.244 -1.334q.0 -.75 .244 -1.31q.25 -.565 .756 -.881q.506 -.315 1.274 -.315q.733 -.0 1.233 .315q.5 .31 .756 .875q.256 .566 .256 1.328zM120.993 86.44q.0 .923 .387 1.458q.393 .53 1.221 .53q.839 .0 1.22 -.53q.387 -.535 .387 -1.458q-.0 -.929 -.387 -1.453q-.381 -.523 -1.209 -.523q-.833 -.0 -1.226 .523q-.393 .524 -.393 1.453z" fill="#FF0D0D" id="mol1atm30" stroke="none"/>
                
            <line class="hi" id="mol1bnd2" stroke="#3050F8" x1="70.374" x2="64.5695" y1="75.825" y2="74.60050000000001"/>
            <line class="hi" id="mol1bnd3" stroke="#3050F8" x1="76.562" x2="80.22" y1="73.322" y2="69.25200000000001"/>
            <line class="hi" id="mol1bnd7" stroke="#3050F8" x1="60.737" x2="62.483999999999995" y1="36.839" y2="42.192499999999995"/>
            <line class="hi" id="mol1bnd8" stroke="#3050F8" x1="56.23" x2="50.6025" y1="32.005" y2="30.1945"/>
            <line class="hi" id="mol1bnd15" stroke="#1FF01F" x1="6.875" x2="12.717" y1="6.396" y2="9.77"/>
            <line class="hi" id="mol1bnd16" stroke="#3050F8" x1="56.23" x2="50.6025" y1="9.524" y2="11.334"/>
            <line class="hi" id="mol1bnd16" stroke="#3050F8" x1="56.23" x2="50.6025" y1="9.524" y2="11.334"/>
            <line class="hi" id="mol1bnd17" stroke="#3050F8" x1="62.109" x2="65.2765" y1="12.053" y2="16.4085"/>
            <line class="hi" id="mol1bnd17" stroke="#3050F8" x1="62.109" x2="65.2765" y1="12.053" y2="16.4085"/>
            <line class="hi" id="mol1bnd18" stroke="#3050F8" x1="62.109" x2="65.2765" y1="29.476" y2="25.119999999999997"/>
            <line class="hi" id="mol1bnd20" stroke="#3050F8" x1="74.919" x2="76.66550000000001" y1="80.304" y2="85.6575"/>
            <line class="hi" id="mol1bnd23" stroke="#3050F8" x1="109.651" x2="103.8505" y1="111.101" y2="109.8755"/>
            <line class="hi" id="mol1bnd24" stroke="#3050F8" x1="114.619" x2="116.8905" y1="115.529" y2="120.63749999999999"/>
            <line class="hi" id="mol1bnd31" stroke="#3050F8" x1="136.617" x2="135.466" y1="112.991" y2="118.553"/>
            <line class="hi" id="mol1bnd31" stroke="#3050F8" x1="136.617" x2="135.466" y1="112.991" y2="118.553"/>
            <line class="hi" id="mol1bnd32" stroke="#3050F8" x1="134.253" x2="129.2405" y1="107.357" y2="104.476"/>
            <line class="hi" id="mol1bnd33" stroke="#3050F8" x1="115.94" x2="120.084" y1="109.102" y2="105.3485"/>
        </g>
          
    </g>
    
</svg>
","Title":"Domperidone","UNII":"5587267Z69","Wikidata":"Q424238","XLogP":3.9}