{"Abbreviation":"","Aliases":["Dioxifedrina","Dioxifedrinum","Dioxyphedrine","Dioxifedrin","3,4-Dihydroxy-α-(1-(methylamino)ethyl)benzyl alcohol","dioxyphAdrine","233-716-9","α-Methylepinephrine","3,4-dihydroxy-α-(1-(methylamino)ethyl)benzyl aldohol"],"CAS":"10329-60-9","ChEMBL":"CHEMBL416557","ChemicalClasses":["phenylethanolamine","catecholamine"],"Chirality":"unknown","Classes":["Sympathomimetic"],"Dosing Info":[],"DrugClasses":[],"DurationOfAction":"","EINECS":"233-716-9","EliminationHalfLife":"","European Community (EC) Number":"233-716-9","HeavyAtomCount":14,"IUPACName":"4-[1-hydroxy-2-(methylamino)propyl]benzene-1,2-diol","InChI":"InChI=1S/C10H15NO3/c1-6(11-2)10(14)7-3-4-8(12)9(13)5-7/h3-6,10-14H,1-2H3","InChIKey":"DDBFLXGTCAVAFD-UHFFFAOYSA-N","MolecularFormula":"C\u003csub\u003e10\u003c/sub\u003eH\u003csub\u003e15\u003c/sub\u003eNO\u003csub\u003e3\u003c/sub\u003e","MolecularWeight":"197.23 g/mol","Opticalactivity":"UNSPECIFIED","PrevSalts":[],"PubChemId":13683,"Record Description":["Dioxifedrine is a beta-2 -adrenergic agonist with bronchodilator activity. Dioxifedrine selectively binds to and activates beta-2 adrenergic receptors in bronchiolar smooth muscle, thereby causing stimulation of adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased intracellular cAMP levels cause relaxation of bronchial smooth muscle. This increases air flow and prevents bronchospasms and may eventually lead to an improvement of airway function."],"References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Dioxifedrine","Name":"Dioxifedrine","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q27275430","Name":"Dioxifedrine","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/13683","Name":"Dioxifedrine","Sub":false}]},{"Name":"ChEMBL","Urls":[{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL416557","Name":"Dioxifedrine","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=10329-60-9","Name":"Dioxifedrine","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/CF48QOH154","Name":"Dioxifedrine","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID40864249","Name":"Dioxifedrine","Sub":false}]}],"SMILES":"CC(C(C1=CC(=C(C=C1)O)O)O)NC","Scheduling":[],"StoreUNII":["CF48QOH154"],"StructureBase64":"<svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" height="51.882mm" version="1.2" viewBox="0 0 100.557 51.882" width="100.557mm">
      
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