{"Abbreviation":[],"Aliases":["3-(Diethylamino)-2,2-dimethylpropyl 4-aminobenzoate","(3-Diethylamino-2,2-dimethyl)propyl 4-aminobenzoat","1-Propanol, 3-(diethylamino)-2,2-dimethyl-, 4-aminobenzoate","RefChem:134182","Larocaine","1-Propanol, 3-(diethylamino)-2,2-dimethyl-, p-aminobenzoate","3-Diethylamino-2,2-dimethylpropyl 4-Aminobenzoate","2-Dicyclohexylphosphino-2',6'-bis(N,N-dimethylamino)biphenyl; 2'-(Dicyclohexylphosphino)-N2,N2,N6,N6-tetramethylbiphenyl-2,6-diamine","4-Aminobenzoesaeure-3-diethylamino-2,2-dimethylproplylester","1-Propanol, 2-[(diethylamino)methyl]-2-methyl-, 1-(4-aminobenzoate)","Msk162629-100a","Wln: zr dvo1x1\u00261\u00261n2\u00262","1-Propanol,2-dimethyl-, p-aminobenzoate","DS-16345","HY-121870","CS-0083580","D4179","F12666","Dimethocaine Solution in Acetonitrile, 100ug/mL","1-Propanol,2-dimethyl-, 4-aminobenzoate","A844843","[3-(diethylamino)-2,2-dimethyl-propyl] 4-aminobenzoate","3-(Diethylamino)-2,2-dimethylpropyl 4-aminobenzoate #","3-(Dimethylamino)-2,2-dimethyl-1-propanol p-aminobenzoate","4-Aminobenzoic Acid 3-Diethylamino-2,2-dimethylpropyl Ester"],"CAS":"94-15-5","ChEBI":"CHEBI:135154","ChEMBL":"CHEMBL4752832","ChemicalClasses":["carboxylic acid"],"Chirality":"achiral","Classes":["Sodium channel blocker","Stimulant"],"Esters":[],"Formating":[],"HeavyAtomCount":20,"IUPACName":"[3-(diethylamino)-2,2-dimethylpropyl] 4-aminobenzoate","InChI":"InChI=1S/C16H26N2O2/c1-5-18(6-2)11-16(3,4)12-20-15(19)13-7-9-14(17)10-8-13/h7-10H,5-6,11-12,17H2,1-4H3","InChIKey":"OWQIUQKMMPDHQQ-UHFFFAOYSA-N","LDLo":[{"dosages":[{"amount":"380 mg/kg","route":"subcutaneous"},{"amount":"40 mg/kg","route":"intravenous"}],"organism":"Mouse"},{"dosages":[{"amount":"150 mg/kg","route":"subcutaneous"},{"amount":"150 mg/kg","route":"intravenous"}],"organism":"Rabbit"},{"dosages":[{"amount":"200 mg/kg","route":"subcutaneous"}],"organism":"Guinea pig"},{"dosages":[{"amount":"860 mg/kg","route":"parenteral"}],"organism":"Frog"}],"MeSH Pharmacological Classification":"Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman\u0026apos;s The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.","MolecularFormula":"C\u003csub\u003e16\u003c/sub\u003eH\u003csub\u003e26\u003c/sub\u003eN\u003csub\u003e2\u003c/sub\u003eO\u003csub\u003e2\u003c/sub\u003e","MolecularWeight":"278.39 g/mol","PubChemId":7177,"Record Description":["Wikipedia|List of designer drugs|Stimulants|Misc"],"RefCount":3,"RefCur":"","References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Dimethocaine","Name":"Dimethocaine","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q3827109","Name":"Dimethocaine","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/7177","Name":"Dimethocaine","Sub":false}]},{"Name":"ChEMBL","Urls":[{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4752832","Name":"Dimethocaine","Sub":false}]},{"Name":"ChEBI","Urls":[{"Link":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:135154","Name":"Dimethocaine","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=94-15-5","Name":"Dimethocaine","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/R3L4A6GOWZ","Name":"Dimethocaine","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID40240185","Name":"Dimethocaine","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 7177, Dimethocaine. Accessed October 7, 2025. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/7177\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/7177\u003c/a\u003e","U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Dimethocaine. UNII: R3L4A6GOWZ. Global Substance Registration System. Accessed October 7, 2025. \u003ca href=https://gsrs.ncats.nih.gov/ginas/app/beta/substances/R3L4A6GOWZ\u003ehttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/R3L4A6GOWZ\u003c/a\u003e"],"SMILES":"CCN(CC)CC(C)(C)COC(=O)C1=CC=C(C=C1)N","SaltData":[{"AcidCount":1,"Amine":"Dimethocaine","AmineCount":1,"Formula":"O=C(O)c1ccccc1O","Name":"salicylate","Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 198.206 95.559\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#ff0d0d\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h199v96H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"m14.236 94.521 13.199-7.62M27.435 86.901v-11.39M24.281 69.841l-10.045-5.8M14.236 64.041l-13.198 7.62M30.588 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libido","Stamina enhancement","Stimulation","Appetite suppression","Dehydration","Dry mouth","Restless legs","Shakiness","Teeth grinding","Abnormal heartbeat","Increased blood pressure","Increased heart rate","Vasoconstriction"],"Visual Effects":[]},"Title":"Dimethocaine","UNII":"R3L4A6GOWZ","Wikidata":"Q3827109","Wikipedia":"Dimethocaine","XLogP":3.1}