{"Abbreviation":"DFE","Aliases":["1,1-Difluoroethane","Ethylidene fluoride","Ethane, 1,1-difluoro-","Ethylidene difluoride","HFC-152a","Freon 152a","Propellant 152a","Halocarbon 152A","Refrigerant 152a","Algofrene type 67"],"Biological Half-Life":"... To investigate DFE toxicokinetics, groups (n = 3) of Sprague-Dawley rats were exposed to 30 s of 20 L/min DFE. ... Plots of concentration (log) versus time were consistent with a two compartment model. Initial distribution was rapid with average half life (t((1/2))) during the alpha phase of 9 s for blood, 18 s for brain and 27 s in cardiac tissue. During beta slope elimination average t((1/2)) was 86 s in blood, 110 s in brain and 168 s in heart. Late elimination half lives were longer with blood gamma = 240 s, brain gamma = 340 s, and heart gamma = 231 s. ...","Boiling Point":"52.3 °","CAS":"75-37-6","ChEMBL":"CHEMBL325493","ChemicalClasses":[],"Chirality":"achiral","Classes":null,"Color/Form":"Colorless gas","Density":"0.95 at 68 °F (USCG, 1999) - Less dense than water; will float g/cm\u003csup\u003e3\u003c/sup\u003e","Dosing Info":[],"DrugClasses":[],"EINECS":"200-866-1","European Community (EC) Number":"200-866-1","Flash Point":"\u003c -50 °C (open cup)","HMDB ID":"HMDB0244022","HeavyAtomCount":4,"IUPACName":"1,1-difluoroethane","InChI":"InChI=1S/C2H4F2/c1-2(3)4/h2H,1H3","InChIKey":"NPNPZTNLOVBDOC-UHFFFAOYSA-N","Melting Point":"-179 °F (USCG, 1999)","MolecularFormula":"C\u003csub\u003e2\u003c/sub\u003eH\u003csub\u003e4\u003c/sub\u003eF\u003csub\u003e2\u003c/sub\u003e","MolecularWeight":"66.05 g/mol","Odor":"Odorless","Physical Description":"1,1-Difluoroethane is colorless, odorless gas shipped as a liquefied gas under its vapor pressure. Contact with the liquid can cause frostbite. It is easily ignited. Its vapors are heavier than air and a flame can travel back to the source of leak very easily. This leak can be either a liquid or vapor leak. It can asphyxiate by the displacement of air. Under prolonged exposure to fire or heat the containers may rupture violently and rocket.","PrevSalts":[],"PubChemId":6368,"Record Description":["1,1-Difluoroethane is colorless, odorless gas shipped as a liquefied gas under its vapor pressure. Contact with the liquid can cause frostbite. It is easily ignited. Its vapors are heavier than air and a flame can travel back to the source of leak very easily. This leak can be either a liquid or vapor leak. It can asphyxiate by the displacement of air. Under prolonged exposure to fire or heat the containers may rupture violently and rocket."],"References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/1,1-Difluoroethane","Name":"Difluoroethane","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q161285","Name":"Difluoroethane","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/6368","Name":"Difluoroethane","Sub":false}]},{"Name":"ChEMBL","Urls":[{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL325493","Name":"Difluoroethane","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=75-37-6","Name":"Difluoroethane","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0244022","Name":"Difluoroethane","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/0B1U8K2ME0","Name":"Difluoroethane","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID0024050","Name":"Difluoroethane","Sub":false}]}],"SMILES":"CC(F)F","Solubility":"In water, 3.2X10+3 mg/L at 25 °C","Stability/Shelf Life":"Stable under recommended storage conditions.","StoreUNII":["0B1U8K2ME0"],"StructureBase64":"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","Title":"Difluoroethane","UNII":"0B1U8K2ME0","Wikidata":"Q161285","Wikipedia":"1,1-Difluoroethane","XLogP":1.4}