{"ATC Code":"L - Antineoplastic and immunomodulating agents","Abbreviation":"DES","Aliases":["Stilbestrol","Stilboestrol","Distilbene","Estrobene","Estromenin","Stilbetin","Stilboestroform","Antigestil","Palestrol","Synestrin"],"CAS":"56-53-1","ChEBI":"CHEBI:41922","ChEMBL":"CHEMBL411","ChemicalClasses":[],"Chirality":"achiral","Color/Form":"White crystalline powder","Decomposition":"When heated to decomposition it emits acrid smoke and fumes.","Dosing Info":[],"Drug Indication":"Used in the treatment of prostate cancer. Previously used in the prevention of miscarriage or premature delivery in pregnant women prone to miscarriage or premature delivery.","Drug Warnings":"Nausea \u0026 vomiting are an initial reaction...Fullness \u0026 tenderness of the breast \u0026 edema...Severe migraine in some...Reactivate or exacerbate endometriosis and its attendant pain. /Estrogens/","DrugClasses":[],"EINECS":"200-278-5","EliminationHalfLife":"24 hours","Esters":["propionate","dipropionate"],"European Community (EC) Number":"200-278-5","HMDB ID":"HMDB0302859","HeavyAtomCount":20,"Human Drugs":"Human drug -\u003e Discontinued; Active ingredient (DIETHYLSTILBESTROL)","IUPACName":"4-[(E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol","InChI":"InChI=1S/C18H20O2/c1-3-17(13-5-9-15(19)10-6-13)18(4-2)14-7-11-16(20)12-8-14/h5-12,19-20H,3-4H2,1-2H3/b18-17+","InChIKey":"RGLYKWWBQGJZGM-ISLYRVAYSA-N","MeSH Pharmacological Classification":"Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included. (See all compounds classified as Carcinogens.)","Melting Point":"336 to 342 °F (NTP, 1992)","MolecularFormula":"C\u003csub\u003e18\u003c/sub\u003eH\u003csub\u003e20\u003c/sub\u003eO\u003csub\u003e2\u003c/sub\u003e","MolecularWeight":"268.3 g/mol","Odor":"Odorless","Pharmacodynamics":"Diethylstilbestrol is a synthetic estrogen that was developed to supplement a woman's natural estrogen production. In 1971, the Food and Drug Administration (FDA) issued a Drug Bulletin advising physicians to stop prescribing DES to pregnant women because it was linked to a rare vaginal cancer in female offspring.","Physical Description":"Diethylstilbestrol is an odorless tasteless white crystalline powder. (NTP, 1992)","PrevSalts":[],"PubChemId":448537,"Record Description":["Diethylstilbestrol (DES) can cause cancer according to California Labor Code. It can cause developmental toxicity according to state or federal government labeling requirements.","Diethylstilbestrol is an odorless tasteless white crystalline powder. (NTP, 1992)","Diethylstilbestrol is an olefinic compound that is trans-hex-3-ene in which the hydrogens at positions 3 and 4 have been replaced by p-hydroxyphenyl groups. It has a role as an antineoplastic agent, a carcinogenic agent, a xenoestrogen, an EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor, an antifungal agent, an endocrine disruptor, an EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor, an autophagy inducer and a calcium channel blocker. It is a polyphenol and an olefinic compound.","A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. (Merck, 11th ed)  The FDA withdrew its approval for the use of all oral and parenteral drug products containing 25 milligrams or more of diethylstilbestrol per unit dose.","Diethylstilbestrol is a synthetic, nonsteroidal form of estrogen. A well-known teratogen and carcinogen, diethylstilbestrol inhibits the hypothalamic-pituitary-gonadal axis, thereby blocking the testicular synthesis of testosterone, lowering plasma testosterone, and inducing a chemical castration.","DIETHYLSTILBESTROL is a small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1973 and is indicated for neoplasm and has 1 investigational indication.","A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen.","A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. (Merck, 11th ed)","Diethylstilbestrol (DES) can cause cancer according to California Labor Code. It can cause developmental toxicity according to state or federal government labeling requirements.","Diethylstilbestrol is an olefinic compound that is trans-hex-3-ene in which the hydrogens at positions 3 and 4 have been replaced by p-hydroxyphenyl groups. It has a role as an antineoplastic agent, a carcinogenic agent, a xenoestrogen, an EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor, an antifungal agent, an endocrine disruptor, an EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor, an autophagy inducer and a calcium channel blocker. It is a polyphenol and an olefinic compound."],"References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Diethylstilbestrol","Name":"Diethylstilbestrol","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q423989","Name":"Diethylstilbestrol","Sub":false}]},{"Name":"DrugBank","Urls":[{"Link":"https://go.drugbank.com/drugs/DB00255","Name":"Diethylstilbestrol","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/448537","Name":"Diethylstilbestrol","Sub":false}]},{"Name":"ChEMBL","Urls":[{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL411","Name":"Diethylstilbestrol","Sub":false}]},{"Name":"ChEBI","Urls":[{"Link":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:41922","Name":"Diethylstilbestrol","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=56-53-1","Name":"Diethylstilbestrol","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0302859","Name":"Diethylstilbestrol","Sub":false}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/C07620","Name":"Diethylstilbestrol","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/731DCA35BT","Name":"Diethylstilbestrol","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID3020465","Name":"Diethylstilbestrol","Sub":false}]}],"SMILES":"CC/C(=C(/CC)\\C1=CC=C(C=C1)O)/C2=CC=C(C=C2)O","Scheduling":[],"Solubility":"less than 1 mg/mL at 68 °F (NTP, 1992)","StoreUNII":["731DCA35BT"],"StructureBase64":"<svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" height="83.074mm" version="1.2" viewBox="0 0 119.791 83.074" width="119.791mm">
      
    <desc>Generated by the Chemistry Development Kit (http://github.com/cdk)</desc>
      
    <g fill="#FF0D0D" stroke="#000000" stroke-linecap="round" stroke-linejoin="round" stroke-width=".7">
            
        <rect fill="#FFFFFF" height="84.0" stroke="none" width="120.0" x=".0" y=".0"/>
            
        <g class="mol" id="mol1">
                  
            <line class="bond" id="mol1bnd1" x1="73.365" x2="73.29" y1="10.915" y2="26.155"/>
                  
            <line class="bond" id="mol1bnd2" x1="73.29" x2="60.054" y1="26.155" y2="33.71"/>
                  
            <g class="bond" id="mol1bnd3">
                        
                <line x1="61.277" x2="61.195" y1="33.012" y2="49.659"/>
                        
                <line x1="58.839" x2="58.757" y1="33.0" y2="49.647"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd4" x1="59.979" x2="46.744" y1="48.95" y2="56.505"/>
                  
            <line class="bond" id="mol1bnd5" x1="46.744" x2="33.583" y1="56.505" y2="48.82"/>
                  
            <line class="bond" id="mol1bnd6" x1="59.979" x2="73.14" y1="48.95" y2="56.634"/>
                  
            <g class="bond" id="mol1bnd7">
                        
                <line x1="73.14" x2="72.99" y1="56.634" y2="71.874"/>
                        
                <line x1="75.565" x2="75.442" y1="58.05" y2="70.506"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd8" x1="72.99" x2="85.818" y1="71.874" y2="79.62"/>
                  
            <g class="bond" id="mol1bnd9">
                        
                <line x1="85.818" x2="99.608" y1="79.62" y2="72.136"/>
                        
                <line x1="85.882" x2="97.184" y1="76.811" y2="70.677"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd10" x1="99.608" x2="99.758" y1="72.136" y2="56.896"/>
                  
            <g class="bond" id="mol1bnd11">
                        
                <line x1="99.758" x2="86.118" y1="56.896" y2="49.142"/>
                        
                <line x1="97.305" x2="86.127" y1="58.307" y2="51.952"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd12" x1="73.14" x2="86.118" y1="56.634" y2="49.142"/>
                  
            <line class="bond" id="mol1bnd13" x1="99.608" x2="109.413" y1="72.136" y2="78.036"/>
                  
            <line class="bond" id="mol1bnd14" x1="60.054" x2="46.894" y1="33.71" y2="26.025"/>
                  
            <g class="bond" id="mol1bnd15">
                        
                <line x1="33.696" x2="46.894" y1="33.645" y2="26.025"/>
                        
                <line x1="33.682" x2="44.469" y1="30.837" y2="24.609"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd16" x1="33.696" x2="20.645" y1="33.645" y2="26.28"/>
                  
            <g class="bond" id="mol1bnd17">
                        
                <line x1="20.386" x2="20.645" y1="10.592" y2="26.28"/>
                        
                <line x1="22.848" x2="23.06" y1="11.986" y2="24.843"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd18" x1="20.386" x2="33.584" y1="10.592" y2="2.972"/>
                  
            <g class="bond" id="mol1bnd19">
                        
                <line x1="47.041" x2="33.584" y1="11.04" y2="2.972"/>
                        
                <line x1="44.589" x2="33.561" y1="12.413" y2="5.801"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd20" x1="46.894" x2="47.041" y1="26.025" y2="11.04"/>
                  
            <line class="bond" id="mol1bnd21" x1="20.386" x2="10.415" y1="10.592" y2="4.944"/>
                  
            <g class="atom" id="mol1atm13">
                        
                <path d="M114.925 79.99q.0 .756 -.256 1.328q-.256 .565 -.756 .881q-.5 .315 -1.244 .315q-.756 .0 -1.262 -.315q-.506 -.316 -.756 -.887q-.244 -.572 -.244 -1.334q-.0 -.75 .244 -1.309q.25 -.566 .756 -.881q.506 -.316 1.274 -.316q.732 .0 1.232 .316q.5 .309 .756 .875q.256 .565 .256 1.327zM111.062 79.99q-.0 .923 .387 1.459q.393 .53 1.22 .53q.839 -.0 1.22 -.53q.387 -.536 .387 -1.459q.0 -.928 -.387 -1.452q-.381 -.524 -1.208 -.524q-.833 -.0 -1.226 .524q-.393 .524 -.393 1.452z" stroke="none"/>
                        
                <path d="M119.231 82.443h-.619v-2.286h-2.512v2.286h-.613v-4.899h.613v2.071h2.512v-2.071h.619v4.899z" stroke="none"/>
                      
            </g>
                  
            <g class="atom" id="mol1atm20">
                        
                <path d="M9.385 3.078q-.0 .756 -.256 1.328q-.256 .565 -.756 .881q-.5 .315 -1.245 .315q-.756 .0 -1.262 -.315q-.506 -.316 -.756 -.887q-.244 -.572 -.244 -1.334q.0 -.75 .244 -1.309q.25 -.566 .756 -.881q.506 -.316 1.274 -.316q.733 .0 1.233 .316q.5 .309 .756 .875q.256 .565 .256 1.327zM5.521 3.078q.0 .923 .387 1.459q.393 .53 1.22 .53q.84 -.0 1.221 -.53q.387 -.536 .387 -1.459q-.0 -.929 -.387 -1.452q-.381 -.524 -1.209 -.524q-.833 -.0 -1.226 .524q-.393 .523 -.393 1.452z" stroke="none"/>
                        
                <path d="M4.305 5.531h-.62v-2.286h-2.512v2.286h-.613v-4.9h.613v2.072h2.512v-2.072h.62v4.9z" stroke="none"/>
                      
            </g>
                
            <line class="hi" id="mol1bnd13" stroke="#FF0D0D" x1="109.413" x2="104.51050000000001" y1="78.036" y2="75.086"/>
            <line class="hi" id="mol1bnd21" stroke="#FF0D0D" x1="10.415" x2="15.4005" y1="4.944" y2="7.768000000000001"/>
            <line class="hi" id="mol1bnd21" stroke="#FF0D0D" x1="10.415" x2="15.4005" y1="4.944" y2="7.768000000000001"/>
        </g>
          
    </g>
    
</svg>
","Therapeutic Uses":"...DES also have been used in the treatment of prostate cancer to reduce testicular androgen production secondary to inhibition of LH release from the pituitary.","Title":"Diethylstilbestrol","UNII":"731DCA35BT","Wikidata":"Q423989","Wikipedia":"Diethylstilbestrol","XLogP":5.1}