{"ATC Code":"P - Antiparasitic products, insecticides and repellents","Abbreviation":["DDT"],"Adverse Effects":"Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.","Aliases":["1-Chloro-4-[2,2,2-trichloro-1-(4-chlorophenyl)ethyl]benzene","1-Chloro-4-(2,2,2-trichloro-1-(4-chlorophenyl)ethyl)benzene","RefChem:127031","Clofenotane","p,p'-DDT","Chlorophenothane","4,4'-DDT","Dicophane","DDT","Chlorphenothan","Chlorphenotoxum","Parachlorocidum","Pentachlorin","Zerdane","Arkotine","Benzochloryl","Bovidermol","Estonate","Guesarol","Santobane","Agritan","Anofex","Deoval","Detoxan","Didigam"],"Associated Disorders and Diseases":"Organochlorine insecticides, acute poisoning [Category: Acute Poisoning]","Biological Half-Life":"1-2 years to eliminate absorbed dose; [TDR, p. 440]","Boiling Point":"500 °","CAS":"50-29-3","ChEBI":"CHEBI:16130","ChEMBL":"CHEMBL416898","ChemicalClasses":["alkylbenzene"],"Chirality":"achiral","Classes":[],"Color/Form":"Biaxial elongated tablets, needles from 95% alcohol","Decomposition":"Decomp at 110 °C; dehydrochlorinates in alkali or org bases when in org solvents","Density":"1.56 at 59 °F (USCG, 1999) - Denser than water; will sink g/cm\u003csup\u003e3\u003c/sup\u003e","Drug Warnings":"Food and Environmental Agents: Effect on Breast-Feeding: DDT: None. /from Table 7/","EINECS":"200-024-3","Ecotoxicity Values":"LC50; Species: Colinus virginianus (Bobwhite quail, 2 weeks old) oral ad libitum 611 ppm for 5 days (95% confidence limit: 514-724 ppm)","Esters":[],"European Community (EC) Number":"200-024-3","Flash Point":"324 to 340 °F (NTP, 1992)","Formating":[],"HMDB ID":"HMDB0032127","HeavyAtomCount":19,"IUPACName":"1-chloro-4-[2,2,2-trichloro-1-(4-chlorophenyl)ethyl]benzene","InChI":"InChI=1S/C14H9Cl5/c15-11-5-1-9(2-6-11)13(14(17,18)19)10-3-7-12(16)8-4-10/h1-8,13H","InChIKey":"YVGGHNCTFXOJCH-UHFFFAOYSA-N","Interactions":"... In rat, combined administration of DDT and aldrin leads to increased excretion of dieldrin. In beagles, repeated administration of DDT plus aldrin resulted in markedly augmented retention of DDT in blood and body fat. Pretreatment of rats \u0026 sheep with DDT has been shown to potentiate hepatotoxicity of carbon tetrachloride.","LD50":[{"dosages":[{"amount":"87 mg/kg","route":"oral"},{"amount":"1931 mg/kg","route":"skin"},{"amount":"9100 μg/kg","route":"intraperitoneal"},{"amount":"1500 mg/kg","route":"subcutaneous"}],"organism":"Rat"},{"dosages":[{"amount":"135 mg/kg","route":"oral"},{"amount":"32 mg/kg","route":"intraperitoneal"}],"organism":"Mouse"},{"dosages":[{"amount":"150 mg/kg","route":"oral"}],"organism":"Dog"},{"dosages":[{"amount":"200 mg/kg","route":"oral"}],"organism":"Monkey"},{"dosages":[{"amount":"250 mg/kg","route":"oral"},{"amount":"300 mg/kg","route":"skin"},{"amount":"250 mg/kg","route":"subcutaneous"}],"organism":"Rabbit"},{"dosages":[{"amount":"150 mg/kg","route":"oral"},{"amount":"1 gm/kg","route":"skin"},{"amount":"900 mg/kg","route":"subcutaneous"}],"organism":"Guinea pig"},{"dosages":[{"amount":"\u0026gt;5 gm/kg","route":"oral"}],"organism":"Hamster"},{"dosages":[{"amount":"7600 μg/kg","route":"oral"},{"amount":"24100 μg/kg","route":"parenteral"}],"organism":"Frog"}],"LDLo":[{"dosages":[{"amount":"150 mg/kg","route":"oral"}],"organism":"Human - infant"},{"dosages":[{"amount":"500 mg/kg","route":"oral"}],"organism":"Human"},{"dosages":[{"amount":"75 mg/kg","route":"intravenous"}],"organism":"Dog"},{"dosages":[{"amount":"50 mg/kg","route":"intravenous"}],"organism":"Monkey"},{"dosages":[{"amount":"250 mg/kg","route":"oral"},{"amount":"40 mg/kg","route":"intravenous"}],"organism":"Cat"},{"dosages":[{"amount":"50 mg/kg","route":"intravenous"}],"organism":"Rabbit"},{"dosages":[{"amount":"300 mg/kg","route":"oral"}],"organism":"Chicken"},{"dosages":[{"amount":"300 mg/kg","route":"oral"}],"organism":"Domestic animals - goat/sheep"}],"Melting Point":"227 to 228 °F (NTP, 1992)","MolecularFormula":"C\u003csub\u003e14\u003c/sub\u003eH\u003csub\u003e9\u003c/sub\u003eCl\u003csub\u003e5\u003c/sub\u003e","MolecularWeight":"354.5 g/mol","Non-Human Toxicity Values":"LD50 Female rat percutaneous 2510 mg/kg","Odor":"Odorless or with slight aromatic odor","Physical Description":"Odorless colorless solid. Sinks in water. (USCG, 1999)","PubChemId":3036,"RefCount":3,"RefCur":"","References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/DDT","Name":"Dichlorodiphenyltrichloroethane","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q163648","Name":"Dichlorodiphenyltrichloroethane","Sub":false}]},{"Name":"DrugBank","Urls":[{"Link":"https://go.drugbank.com/drugs/DB13424","Name":"Dichlorodiphenyltrichloroethane","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/3036","Name":"Dichlorodiphenyltrichloroethane","Sub":false}]},{"Name":"ChEMBL","Urls":[{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL416898","Name":"Dichlorodiphenyltrichloroethane","Sub":false}]},{"Name":"ChEBI","Urls":[{"Link":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:16130","Name":"Dichlorodiphenyltrichloroethane","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=50-29-3","Name":"Dichlorodiphenyltrichloroethane","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0032127","Name":"Dichlorodiphenyltrichloroethane","Sub":false}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/C04623","Name":"Dichlorodiphenyltrichloroethane","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/CIW5S16655","Name":"Dichlorodiphenyltrichloroethane","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID4020375","Name":"Dichlorodiphenyltrichloroethane","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 3036, Dichlorodiphenyltrichloroethane. Accessed September 13, 2025. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/3036\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/3036\u003c/a\u003e","U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Dichlorodiphenyltrichloroethane. UNII: CIW5S16655. Global Substance Registration System. Accessed September 13, 2025. \u003ca href=https://gsrs.ncats.nih.gov/ginas/app/beta/substances/CIW5S16655\u003ehttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/CIW5S16655\u003c/a\u003e"],"SMILES":"C1=CC(=CC=C1C(C2=CC=C(C=C2)Cl)C(Cl)(Cl)Cl)Cl","SaltData":[],"Salts":[],"Solubility":"less than 1 mg/mL at 70 °F (NTP, 1992)","Stability/Shelf Life":"Resistant to destruction by light and oxidation","StereoisomerData":[],"Stereoisomers":[],"Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 88.362 98.108\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#1ff01f\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h89v99H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m31.763 94.877 13.198-7.62M31.763 92.061l10.759-6.211\"/\u003e\u003c/g\u003e\u003cpath d=\"M31.763 94.877 18.56 87.249\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m18.555 72 .005 15.249M20.994 73.408l.004 12.433\"/\u003e\u003c/g\u003e\u003cpath d=\"m18.555 72 13.198-7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M44.956 72.009 31.753 64.38M42.518 73.416l-10.765-6.22\"/\u003e\u003c/g\u003e\u003cpath d=\"m44.961 87.257-.005-15.248M44.956 72.009l13.198-7.62M58.154 64.389v-15.24\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m45.112 41.594 13.042 7.555M47.543 40.184l10.611 6.147\"/\u003e\u003c/g\u003e\u003cpath d=\"m45.112 41.594-.077-15.24\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m58.001 18.567-12.966 7.787M58.029 21.395 47.48 27.73\"/\u003e\u003c/g\u003e\u003cpath d=\"m58.001 18.567 13.348 7.655\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m71.426 41.462-.077-15.24M68.98 40.06l-.062-12.421\"/\u003e\u003c/g\u003e\u003cpath d=\"m58.154 49.149 13.272-7.687M58.001 18.567l-.114-11.321M58.154 64.389l13.199 7.62M71.353 72.009l5.756-9.971M71.353 72.009l10.252 5.919M71.353 72.009l-6.62 11.465M18.56 87.249 6.875 93.995\" class=\"bond\"/\u003e\u003cpath stroke=\"none\" d=\"M58.341 1.352q-.785 0-1.238.53-.452.523-.452 1.446 0 .911.416 1.447.423.53 1.268.53.322 0 .608-.054.291-.059.565-.143v.536q-.274.101-.565.149-.292.053-.697.053-.744 0-1.25-.309-.5-.31-.75-.875-.25-.572-.25-1.34 0-.744.268-1.309.274-.566.803-.881.53-.322 1.28-.322.78 0 1.352.286l-.244.524q-.227-.102-.506-.185-.274-.083-.608-.083m2.757 4.423h-.601V.56h.601zM79.467 56.834q-.786 0-1.238.53-.453.524-.453 1.446 0 .911.417 1.447.422.53 1.268.53.321 0 .607-.054.292-.059.566-.143v.536q-.274.101-.566.149-.292.054-.696.054-.745 0-1.251-.31-.5-.31-.75-.875-.25-.572-.25-1.34 0-.744.268-1.309.274-.566.804-.881.53-.322 1.28-.322.78 0 1.351.286l-.244.524q-.226-.101-.506-.185-.274-.083-.607-.083m2.756 4.423h-.601v-5.215h.601zM85.045 77.652q-.786 0-1.238.53-.453.524-.453 1.447 0 .91.417 1.446.423.53 1.268.53.322 0 .607-.053.292-.06.566-.143v.535q-.274.102-.566.149-.291.054-.696.054-.744 0-1.25-.31-.5-.309-.75-.875-.251-.571-.251-1.339 0-.744.268-1.31.274-.566.804-.881.53-.322 1.28-.322.78 0 1.351.286l-.244.524q-.226-.101-.506-.184-.274-.084-.607-.084m2.757 4.423H87.2V76.86h.602zM61.277 83.391q-.786 0-1.239.53-.452.524-.452 1.447 0 .91.417 1.446.422.53 1.268.53.321 0 .607-.054.292-.059.565-.142v.535q-.273.102-.565.149-.292.054-.697.054-.744 0-1.25-.31-.5-.309-.75-.875-.25-.571-.25-1.339 0-.744.268-1.31.274-.566.804-.881.53-.322 1.28-.322.779 0 1.351.286l-.244.524q-.226-.101-.506-.184-.274-.084-.607-.084m2.756 4.423h-.601v-5.215h.601zM2.906 93.053q-.786 0-1.239.53-.452.524-.452 1.446 0 .911.417 1.447.422.53 1.268.53.321 0 .607-.054.292-.059.565-.143v.536q-.273.101-.565.149-.292.054-.697.054-.744 0-1.25-.31-.5-.31-.75-.875-.25-.572-.25-1.34 0-.744.268-1.309.274-.566.804-.881.529-.322 1.279-.322.78 0 1.352.286l-.244.524q-.226-.101-.506-.185-.274-.083-.607-.083m2.756 4.423h-.601v-5.215h.601z\" class=\"atom\"/\u003e\u003cpath stroke=\"#1ff01f\" d=\"m57.887 7.246.057 5.661M77.109 62.038l-2.878 4.985M81.605 77.928l-5.126-2.959M64.733 83.474l3.31-5.732M6.875 93.995l5.842-3.373\" class=\"hi\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Subjective Effects":null,"TDLo":[{"dosages":[{"amount":"6 mg/kg","route":"oral"}],"organism":"Human - male"},{"dosages":[{"amount":"16 mg/kg","route":"oral"},{"amount":"5 mg/kg","route":"oral"}],"organism":"Human"}],"Therapeutic Uses":"MEDICATION (VET): Has been used on animals ... for spot treatment of screwworm infested wounds (25%).","Title":"Dichlorodiphenyltrichloroethane","UNII":"CIW5S16655","Wikidata":"Q163648","Wikipedia":"DDT","XLogP":6.9}