{"Abbreviation":["2-DPMP"],"Aliases":["2-DPMP","Desoxypipradrol","2-(Diphenylmethyl)piperidine","Deoxypipradol","Piperidine, 2-(diphenylmethyl)-","Unii-49unk1bv8t","Desoxypipradol","Piperidine,2-(diphenylmethyl)-","HSDB 8015","Einecs 208-276-6","2-Diphenylmethyl-piperidine","Oprea1_652788","Schembl729266","Schembl2966244","Dtxsid90897502","Mfcd02663618","STK893433","Akos001476367","LE-0263","FD111892","NS00017679"],"Boiling Point":"150 °C","CAS":"519-74-4","ChemicalClasses":["2-benzylpiperidine"],"Chirality":"racemic","Classes":["Stimulant"],"Color/Form":"Orthrhombic from petroleum","EliminationHalfLife":"16 – 20 hours","Erowid Experience Reports":[{"Author":"Octehedron","Id":86467,"Title":"Trials"},{"Author":"troyw88","Id":90368,"Title":"Mixed Results and Dosage Issues"},{"Author":"troyw88","Id":93695,"Title":"Love It"},{"Author":"AK139","Id":98804,"Title":"Do Not Recommend"},{"Author":"Moksha777","Id":71451,"Title":"3 Day Rollercoaster Ride"},{"Author":"HST","Id":109229,"Title":"Surprise Initiation"}],"Esters":[],"European Community (EC) Number":"208-276-6","Formating":[],"HMDB ID":"HMDB0245105","HeavyAtomCount":19,"IUPACName":"2-benzhydrylpiperidine","InChI":"InChI=1S/C18H21N/c1-3-9-15(10-4-1)18(16-11-5-2-6-12-16)17-13-7-8-14-19-17/h1-6,9-12,17-19H,7-8,13-14H2","InChIKey":"RWTNXJXZVGHMGI-UHFFFAOYSA-N","MeSH Headers":[{"Id":"M0225504","Link":"https://id.nlm.nih.gov/mesh/M0225504.html","Name":"2-diphenylmethylpiperidine","Ref":20},{"Id":"DescTree","Link":"https://www.nlm.nih.gov/mesh/meshhome.html","Name":"MeSH Tree","Ref":22},{"Id":"PubMed from MeSH","Link":"https://www.nlm.nih.gov/mesh/meshhome.html","Name":null,"Ref":33}],"Mechanism of Action":"The ATP-Mg++-dependent uptake of (3)H dopamine and l-(3)H norepinephrine into purified synaptic vesicles of whole rat brain, rat striatum and rat hypothalamus was inhibited 10-fold more effectively by S-(+)-amphetamine as compared to its corresponding (R-(-)-enantiomer. In contrast, S-(+)-deoxypipradrol and its R-(-)-enantiomer were approximately equipotent inhibitors of 3H-amine uptake into these synaptic vesicular preparations. The 1R:2R-methylphenidate was twice as potent as its 1R:2S-enantiomer as an inhibitor of (3)H-catecholamine uptake. These data suggest that the receptor sites on the amine pumps present in the membranes of all three vesicular preparations are similar in so far as they are all sensitive to the stereochemical configuration around the alpha-carbon of amphetamine but are not sensitive to the stereochemical configuration around the analogous carbon of deoxypipradrol and methylphenidate. These observations are the reverse of those previously observed for the phenethylamine pumps present in peripheral and central neuronal membranes.","Melting Point":"66 °C","MolecularFormula":"C\u003csub\u003e18\u003c/sub\u003eH\u003csub\u003e21\u003c/sub\u003eN","MolecularWeight":"251.4 g/mol","Non-Human Toxicity Values":"LD50 Mouse oral 0.080 g/kg","Opticalactivity":"( + / - )","PD":"PD048829","PubChemId":160506,"Record Description":["Wikipedia|List of designer drugs|Stimulants|Tropanes and Piperidines"],"Records":{"UNII":{"Impurities":[]}},"RefChem":"585826","RefCount":3,"RefCur":"","References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Desoxypipradrol","Name":"Desoxypipradrol","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q414480","Name":"Desoxypipradrol","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/160506","Name":"Desoxypipradrol","Sub":false}]},{"Name":"Probes \u0026 Drugs","Urls":[{"Link":"https://www.probes-drugs.org/compound/PD048829","Name":"Desoxypipradrol","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=519-74-4","Name":"Desoxypipradrol","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0245105","Name":"Desoxypipradrol","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/49UNK1BV8T","Name":"Desoxypipradrol","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID90897502","Name":"Desoxypipradrol","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 160506, 2-Diphenylmethylpiperidine. Accessed May 8, 2026. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/160506\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/160506\u003c/a\u003e","U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Desoxypipradrol. UNII: 49UNK1BV8T. Global Substance Registration System. Accessed May 8, 2026. \u003ca href=https://gsrs.ncats.nih.gov/ginas/app/beta/substances/49UNK1BV8T\u003ehttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/49UNK1BV8T\u003c/a\u003e"],"SMILES":"C1CCNC(C1)C(C2=CC=CC=C2)C3=CC=CC=C3","SaltData":[],"Salts":[],"Scheduling":[{"gov":"Germany","ref":[],"schedule":"Anlage II substance"},{"gov":"United Kingdom","ref":[],"schedule":"Class B substance"}],"StereoisomerData":[{"ChemicalClasses":["2-benzylpiperidine"],"SMILES":"C1=CC=C(C(C2=CC=CC=C2)[C@H]2CCCCN2)C=C1","Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 81.246 78.238\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#3050f8\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 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class=\"hi\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Title":"(S)-Desoxypipradrol"}],"StereoisomerType":"enantiomer","Stereoisomers":["(R)-Desoxypipradrol","(S)-Desoxypipradrol"],"Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 81.246 78.238\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#3050f8\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h82v79H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"m67.007 77.198 13.201-7.616M80.208 69.582V54.351M80.208 54.351l-10.047-5.797M63.854 48.554l-10.047 5.797M53.807 54.351v15.231M67.007 77.198l-13.2-7.616M53.807 54.351l-13.19-7.618M40.617 46.733l-13.192 7.613\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M27.425 54.346 14.23 46.72M24.987 55.754l-10.758-6.218\"/\u003e\u003c/g\u003e\u003cpath d=\"M14.23 46.72 1.038 54.334\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m1.038 54.334.003 15.24M3.477 55.742l.002 12.425\"/\u003e\u003c/g\u003e\u003cpath d=\"M1.041 69.574 14.235 77.2\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m14.235 77.2 13.192-7.614M14.236 74.384l10.753-6.206\"/\u003e\u003c/g\u003e\u003cpath d=\"m27.425 54.346.002 15.24M40.617 46.733l.002-15.232\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m27.42 23.883 13.199 7.618M29.859 22.475l10.761 6.211\"/\u003e\u003c/g\u003e\u003cpath d=\"m27.42 23.883.002-15.231\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M40.624 1.038 27.422 8.652M40.624 3.853l-10.763 6.208\"/\u003e\u003c/g\u003e\u003cpath d=\"m40.624 1.038 13.2 7.618\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m53.821 23.888.003-15.232M51.383 22.479l.002-12.415\"/\u003e\u003c/g\u003e\u003cpath d=\"m40.619 31.501 13.202-7.613\" class=\"bond\"/\u003e\u003cg stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M68.948 49.185h-.72l-2.62-4.066h-.029l.029.595q.024.357.024.732v2.739h-.565v-4.9h.714l2.607 4.054h.03l-.018-.327q-.012-.22-.023-.476-.006-.262-.006-.483v-2.768h.577zM68.811 43.723h-.619v-2.286H65.68v2.286h-.613v-4.899h.613v2.072h2.512v-2.072h.619z\"/\u003e\u003c/g\u003e\u003cpath stroke=\"#3050f8\" d=\"m70.161 48.554 5.023 2.899M70.161 48.554l5.023 2.899M63.854 48.554l-5.023 2.899M63.854 48.554l-5.023 2.899\" class=\"hi\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Subjective Effects":{"Cognitive Effects":["Analysis enhancement","Ego inflation","Focus enhancement","Increased music appreciation","Motivation enhancement","Thought acceleration","Wakefulness","Disinhibition","Suggestibility suppression","Cognitive euphoria","Compulsive redosing","Mania"],"Physical Effects":["Increased libido","Stamina enhancement","Stimulation","Appetite suppression","Dehydration","Dry mouth","Restless legs","Shakiness","Teeth grinding","Abnormal heartbeat","Increased blood pressure","Increased heart rate","Vasoconstriction"],"Visual Effects":[]},"Title":"Desoxypipradrol","UNII":"49UNK1BV8T","Wikidata":"Q414480","Wikipedia":"Desoxypipradrol","XLogP":4.1}