{"Abbreviation":"","Aliases":["Dihydrodeoxymorphine","Permonid","Desomorfina","Krokodil","Deoxydihydromorphine D","Dihydrodesoxymorphine D","Desomorphinum","Desomorfin","Dihydrodesoxymorphine-D","4,5-Epoxy-3-hydroxy-N-methylmorphinan"],"Boiling Point":"Sublimes in high vacuum between 140 and 170 °C","CAS":"427-00-9","ChEBI":"CHEBI:135119","ChEMBL":"CHEMBL2106274","ChemicalClasses":["morphinan"],"Chirality":"absolute","Color/Form":"Rectangular plates from acetone-water","DEA no":9055,"Decomposition":"When heated to decomposition it emits toxic fumes of /oxides of nitrogen/.","Dosing Info":[],"Drug Warnings":"/Withdrawal symptoms were studied/ in 6 cases /and/ the drug being used, whether desomorphine or morphine, was withheld for 6-12 hours at about 10-day intervals throughout the course of the study. During these brief withdrawals observations for specific abstinence symptoms were made. Such signs of abstinence began to appear 10 days after the beginning of desomorphine administration. After the third week definite evidence of abstinence was seen if desomorphine was withheld for only 4 hours. No signs of addiction were observed during the short periods of withdrawal in the three patients receiving morphine. It must be remembered, however, that the dose of desomorphine had been increased more rapidly than that of morphine, and also that signs of abstinence from morphine are not ordinarily very apparent within the first 12 hours of withdrawal because of the longer duration of action of this drug.","DrugClasses":["opioid"],"EINECS":"207-045-7","European Community (EC) Number":"207-045-7","FullSalts":["Desomorphine hydrobromide","Desomorphine hydrochloride"],"HeavyAtomCount":20,"IUPACName":"(4R,4aR,7aS,12bS)-3-methyl-2,4,4a,5,6,7,7a,13-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-9-ol","InChI":"InChI=1S/C17H21NO2/c1-18-8-7-17-11-3-2-4-14(17)20-16-13(19)6-5-10(15(16)17)9-12(11)18/h5-6,11-12,14,19H,2-4,7-9H2,1H3/t11-,12+,14-,17+/m0/s1","InChIKey":"LNNWVNGFPYWNQE-GMIGKAJZSA-N","MeSH Pharmacological Classification":"Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS. (See all compounds classified as Analgesics, Opioid.)","MolecularFormula":"C\u003csub\u003e17\u003c/sub\u003eH\u003csub\u003e21\u003c/sub\u003eNO\u003csub\u003e2\u003c/sub\u003e","MolecularWeight":"271.35 g/mol","Opticalactivity":"UNSPECIFIED","PrevSalts":["hydrobromide","hydrochloride"],"PubChemId":5362456,"Record Description":["Desomorphine is a morphinane alkaloid.","Desomorphine is a DEA Schedule I controlled substance. Substances in the DEA Schedule I have no currently accepted medical use in the United States, a lack of accepted safety for use under medical supervision, and a high potential for abuse. It is a Opium derivatives substance.","DESOMORPHINE is a small molecule drug with a maximum clinical trial phase of II.","Desomorphine is a morphinane alkaloid."],"References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Desomorphine","Name":"Desomorphine","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q422163","Name":"Desomorphine","Sub":false}]},{"Name":"DrugBank","Urls":[{"Link":"https://go.drugbank.com/drugs/DB01531","Name":"Desomorphine","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/5362456","Name":"Desomorphine","Sub":false}]},{"Name":"ChemSpider","Urls":[{"Link":"https://www.chemspider.com/Chemical-Structure.4515044.html","Name":"Desomorphine","Sub":false}]},{"Name":"ChEMBL","Urls":[{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2106274","Name":"Desomorphine","Sub":false}]},{"Name":"ChEBI","Urls":[{"Link":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:135119","Name":"Desomorphine","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=427-00-9","Name":"Desomorphine","Sub":false}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/D12670","Name":"Desomorphine","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/7OP86J5E33","Name":"Desomorphine","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID10195390","Name":"Desomorphine","Sub":false}]}],"SMILES":"CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)O)O[C@H]3CCC4","Salts":["hydrobromide","hydrochloride"],"SaltsAcidCount":[1,1],"SaltsAmineCount":[1,1],"SaltsUNII":["9N7P66M943","CPQ4S9YG5F"],"Slang":["Krokodil ","Crocodile "],"Solubility":"Soluble in acetone, ethyl acetate","StoreUNII":["7OP86J5E33"],"StructureBase64":"<svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" height="80.078mm" version="1.2" viewBox="0 0 80.214 80.078" width="80.214mm">
      
    <desc>Generated by the Chemistry Development Kit (http://github.com/cdk)</desc>
      
    <g fill="#000000" stroke="#000000" stroke-linecap="round" stroke-linejoin="round" stroke-width=".7">
            
        <rect fill="#FFFFFF" height="81.0" stroke="none" width="81.0" x=".0" y=".0"/>
            
        <g class="mol" id="mol1">
                  
            <line class="bond" id="mol1bnd1" x1="79.194" x2="74.742" y1="70.462" y2="60.229"/>
                  
            <line class="bond" id="mol1bnd2" x1="73.092" x2="73.016" y1="52.645" y2="41.061"/>
                  
            <line class="bond" id="mol1bnd3" x1="73.016" x2="46.818" y1="41.061" y2="41.061"/>
                  
            <path class="bond" d="M33.442 48.373l.35 .607l18.88 -8.269h-5.247h-3.505z" id="mol1bnd4" stroke="none"/>
                  
            <line class="bond" id="mol1bnd5" x1="33.617" x2="46.716" y1="48.676" y2="56.394"/>
                  
            <line class="bond" id="mol1bnd6" x1="46.716" x2="59.917" y1="56.394" y2="48.778"/>
                  
            <path class="bond" d="M60.094 48.476l-.354 .604l9.379 7.027l.849 -1.453l.85 -1.453z" id="mol1bnd7" stroke="none"/>
                  
            <path class="bond" d="M59.917 49.128c-.001 -.0 -.002 -.0 -.002 -.0c-.175 -.001 -.349 -.177 -.348 -.352l.045 -6.75v.0h.7v-.0l-.045 6.758c-.001 .175 -.176 .348 -.35 .348zM59.625 40.099l.044 -6.453c.001 -.002 .176 -.348 .351 -.348c.0 -.0 .001 -.0 .001 -.0c.175 .001 .349 .177 .348 .352l-.044 6.444v.0h-.7z" id="mol1bnd8" stroke="none"/>
                  
            <line class="bond" id="mol1bnd9" x1="60.019" x2="46.716" y1="33.648" y2="25.931"/>
                  
            <g class="bond" id="mol1bnd10">
                        
                <line x1="33.516" x2="46.716" y1="33.546" y2="25.931"/>
                        
                <line x1="33.516" x2="44.278" y1="30.731" y2="24.522"/>
                      
            </g>
                  
            <g class="bond" id="mol1bnd11">
                        
                <line x1="33.267" x2="33.967" y1="48.679" y2="48.674"/>
                        
                <line x1="32.959" x2="34.242" y1="46.159" y2="46.15"/>
                        
                <line x1="32.65" x2="34.517" y1="43.639" y2="43.627"/>
                        
                <line x1="32.341" x2="34.792" y1="41.12" y2="41.103"/>
                        
                <line x1="32.033" x2="35.066" y1="38.6" y2="38.579"/>
                        
                <line x1="31.724" x2="35.341" y1="36.08" y2="36.056"/>
                        
                <line x1="31.416" x2="35.616" y1="33.56" y2="33.532"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd12" x1="33.516" x2="20.315" y1="33.546" y2="25.931"/>
                  
            <g class="bond" id="mol1bnd13">
                        
                <line x1="20.315" x2="20.315" y1="10.699" y2="25.931"/>
                        
                <line x1="22.753" x2="22.753" y1="12.107" y2="24.522"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd14" x1="20.315" x2="33.516" y1="10.699" y2="3.083"/>
                  
            <g class="bond" id="mol1bnd15">
                        
                <line x1="46.716" x2="33.516" y1="10.699" y2="3.083"/>
                        
                <line x1="44.278" x2="33.516" y1="12.107" y2="5.898"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd16" x1="46.716" x2="46.716" y1="25.931" y2="10.699"/>
                  
            <line class="bond" id="mol1bnd17" x1="20.315" x2="10.401" y1="10.699" y2="4.973"/>
                  
            <line class="bond" id="mol1bnd18" x1="20.315" x2="8.048" y1="25.931" y2="37.292"/>
                  
            <g class="bond" id="mol1bnd19">
                        
                <line stroke="#000000" x1="20.161" x2="20.672" y1="56.43" y2="55.951"/>
                        
                <line stroke="#FF0D0D" x1="18.51" x2="19.277" y1="54.925" y2="54.207"/>
                        
                <line stroke="#FF0D0D" x1="16.86" x2="17.881" y1="53.42" y2="52.462"/>
                        
                <line stroke="#FF0D0D" x1="15.209" x2="16.486" y1="51.915" y2="50.718"/>
                        
                <line stroke="#FF0D0D" x1="13.558" x2="15.09" y1="50.41" y2="48.974"/>
                        
                <line stroke="#FF0D0D" x1="11.907" x2="13.695" y1="48.905" y2="47.229"/>
                        
                <line stroke="#FF0D0D" x1="10.256" x2="12.299" y1="47.4" y2="45.485"/>
                        
                <line stroke="#FF0D0D" x1="8.605" x2="10.904" y1="45.895" y2="43.74"/>
                        
                <line stroke="#FF0D0D" x1="6.955" x2="9.508" y1="44.39" y2="41.996"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd20" x1="33.617" x2="20.417" y1="48.676" y2="56.191"/>
                  
            <line class="bond" id="mol1bnd21" x1="20.417" x2="20.214" y1="56.191" y2="71.219"/>
                  
            <line class="bond" id="mol1bnd22" x1="20.214" x2="33.313" y1="71.219" y2="79.038"/>
                  
            <line class="bond" id="mol1bnd23" x1="33.313" x2="46.615" y1="79.038" y2="71.524"/>
                  
            <g class="bond" id="mol1bnd24">
                        
                <line x1="46.412" x2="47.021" y1="56.566" y2="56.221"/>
                        
                <line x1="46.141" x2="47.258" y1="59.231" y2="58.6"/>
                        
                <line x1="45.87" x2="47.495" y1="61.896" y2="60.978"/>
                        
                <line x1="45.599" x2="47.732" y1="64.561" y2="63.356"/>
                        
                <line x1="45.328" x2="47.969" y1="67.226" y2="65.734"/>
                        
                <line x1="45.057" x2="48.206" y1="69.892" y2="68.112"/>
                        
                <line x1="44.786" x2="48.444" y1="72.557" y2="70.491"/>
                      
            </g>
                  
            <path class="atom" d="M75.058 58.945h-.72l-2.619 -4.066h-.03q.012 .238 .03 .595q.024 .357 .024 .732v2.739h-.566v-4.9h.714l2.608 4.055h.03q-.006 -.108 -.018 -.328q-.012 -.22 -.024 -.476q-.006 -.262 -.006 -.482v-2.769h.577v4.9z" fill="#3050F8" id="mol1atm2" stroke="none"/>
                  
            <g class="atom" id="mol1atm15">
                        
                <path d="M9.385 3.078q-.0 .756 -.256 1.328q-.256 .565 -.756 .881q-.5 .315 -1.245 .315q-.756 .0 -1.262 -.315q-.506 -.316 -.756 -.887q-.244 -.572 -.244 -1.334q.0 -.75 .244 -1.309q.25 -.566 .756 -.881q.506 -.316 1.274 -.316q.733 -.0 1.233 .316q.5 .309 .756 .875q.256 .565 .256 1.327zM5.521 3.078q.0 .923 .387 1.459q.393 .53 1.22 .53q.84 -.0 1.221 -.53q.387 -.536 .387 -1.459q-.0 -.929 -.387 -1.452q-.381 -.524 -1.209 -.524q-.833 -.0 -1.226 .524q-.393 .523 -.393 1.452z" fill="#FF0D0D" stroke="none"/>
                        
                <path d="M4.305 5.531h-.62v-2.286h-2.512v2.286h-.613v-4.9h.613v2.072h2.512v-2.072h.62v4.9z" fill="#FF0D0D" stroke="none"/>
                      
            </g>
                  
            <path class="atom" d="M7.444 39.941q.0 .756 -.256 1.327q-.256 .566 -.756 .881q-.5 .316 -1.244 .316q-.756 -.0 -1.262 -.316q-.506 -.315 -.756 -.887q-.244 -.571 -.244 -1.333q-.0 -.75 .244 -1.31q.25 -.566 .756 -.881q.506 -.316 1.274 -.316q.732 .0 1.232 .316q.5 .31 .756 .875q.256 .566 .256 1.328zM3.581 39.941q-.0 .922 .387 1.458q.393 .53 1.22 .53q.839 -.0 1.22 -.53q.387 -.536 .387 -1.458q.0 -.929 -.387 -1.453q-.381 -.524 -1.208 -.524q-.833 .0 -1.226 .524q-.393 .524 -.393 1.453z" fill="#FF0D0D" id="mol1atm16" stroke="none"/>
                
            <line class="hi" id="mol1bnd1" stroke="#3050F8" x1="74.742" x2="76.968" y1="60.229" y2="65.3455"/>
            <line class="hi" id="mol1bnd2" stroke="#3050F8" x1="73.092" x2="73.054" y1="52.645" y2="46.853"/>
            <line class="hi" id="mol1bnd17" stroke="#FF0D0D" x1="10.401" x2="15.358" y1="4.973" y2="7.836"/>
            <line class="hi" id="mol1bnd17" stroke="#FF0D0D" x1="10.401" x2="15.358" y1="4.973" y2="7.836"/>
            <line class="hi" id="mol1bnd18" stroke="#FF0D0D" x1="8.048" x2="14.1815" y1="37.292" y2="31.6115"/>
        </g>
          
    </g>
    
</svg>
","SwissTargetPredictions":[{"By Homology":"No","ChEMBL ID":"CHEMBL222","Gene Code":"SLC6A2","Number of sim. cmpds (3D)":"0","Number of sim. cmpds (D2)":"234","Probability":"0.43","Target":"Sodium-dependent noradrenaline transporter","Target Class":"Transporter","Uniprot ID":"P23975"},{"By Homology":"No","ChEMBL ID":"CHEMBL228","Gene Code":"SLC6A4","Number of sim. cmpds (3D)":"0","Number of sim. cmpds (D2)":"235","Probability":"0.43","Target":"Sodium-dependent serotonin transporter","Target Class":"Transporter","Uniprot ID":"P31645"},{"By Homology":"No","ChEMBL ID":"CHEMBL238","Gene Code":"SLC6A3","Number of sim. cmpds (3D)":"0","Number of sim. cmpds (D2)":"234","Probability":"0.43","Target":"Sodium-dependent dopamine transporter","Target Class":"Transporter","Uniprot ID":"Q01959"},{"By Homology":"No","ChEMBL ID":"CHEMBL5857","Gene Code":"TAAR1","Number of sim. cmpds (3D)":"0","Number of sim. cmpds (D2)":"12","Probability":"0.43","Target":"Trace amine-associated receptor 1","Target Class":"Membrane receptor","Uniprot ID":"Q96RJ0"},{"By Homology":"Yes","ChEMBL ID":null,"Gene Code":"TAAR2","Number of sim. cmpds (3D)":"0","Number of sim. cmpds (D2)":"12","Probability":"0.43","Target":"Trace amine-associated receptor 2","Target Class":"Membrane receptor","Uniprot ID":"Q9P1P5"},{"By Homology":"Yes","ChEMBL ID":"CHEMBL2337","Gene Code":"SLC6A9","Number of sim. cmpds (3D)":"0","Number of sim. cmpds (D2)":"171","Probability":"0.43","Target":"Sodium- and chloride-dependent glycine transporter 1","Target Class":"Transporter","Uniprot ID":"P48067"},{"By Homology":"Yes","ChEMBL ID":null,"Gene Code":"SLC6A7","Number of sim. cmpds (3D)":"0","Number of sim. cmpds (D2)":"171","Probability":"0.43","Target":"Sodium-dependent proline transporter","Target Class":"Transporter","Uniprot ID":"Q99884"},{"By Homology":"Yes","ChEMBL ID":null,"Gene Code":"SLC6A14","Number of sim. cmpds (3D)":"0","Number of sim. cmpds (D2)":"171","Probability":"0.43","Target":"Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)","Target Class":"Transporter","Uniprot ID":"Q9UN76"},{"By Homology":"Yes","ChEMBL ID":"CHEMBL3060","Gene Code":"SLC6A5","Number of sim. cmpds (3D)":"0","Number of sim. cmpds (D2)":"171","Probability":"0.43","Target":"Sodium- and chloride-dependent glycine transporter 2","Target Class":"Transporter","Uniprot ID":"Q9Y345"},{"By Homology":"No","ChEMBL ID":"CHEMBL6136","Gene Code":"KDM1A","Number of sim. cmpds (3D)":"0","Number of sim. cmpds (D2)":"8","Probability":"0.34","Target":"Lysine-specific histone demethylase 1A","Target Class":"Enzyme","Uniprot ID":"O60341"},{"By Homology":"No","ChEMBL ID":"CHEMBL1951","Gene Code":"MAOA","Number of sim. cmpds (3D)":"0","Number of sim. cmpds (D2)":"36","Probability":"0.34","Target":"Amine oxidase [flavin-containing] A","Target Class":"Enzyme","Uniprot ID":"P21397"},{"By Homology":"No","ChEMBL ID":"CHEMBL2039","Gene Code":"MAOB","Number of sim. cmpds (3D)":"0","Number of sim. cmpds (D2)":"36","Probability":"0.34","Target":"Amine oxidase [flavin-containing] B","Target Class":"Enzyme","Uniprot ID":"P27338"},{"By Homology":"No","ChEMBL ID":"CHEMBL287","Gene Code":"SIGMAR1","Number of sim. cmpds (3D)":"0","Number of sim. cmpds (D2)":"155","Probability":"0.34","Target":"Sigma non-opioid intracellular receptor 1","Target Class":"Membrane receptor","Uniprot ID":"Q99720"},{"By Homology":"No","ChEMBL ID":"CHEMBL224","Gene Code":"HTR2A","Number of sim. cmpds (3D)":"0","Number of sim. cmpds (D2)":"75","Probability":"0.30","Target":"5-hydroxytryptamine receptor 2A","Target Class":"Membrane receptor","Uniprot ID":"P28223"},{"By Homology":"Yes","ChEMBL ID":"CHEMBL225","Gene Code":"HTR2C","Number of sim. cmpds (3D)":"0","Number of sim. cmpds (D2)":"44","Probability":"0.30","Target":"5-hydroxytryptamine receptor 2C","Target Class":"Membrane receptor","Uniprot ID":"P28335"}],"Therapeutic Uses":"THERAPEUTIC CATEGORY: Analgesic (narcotic)","Title":"Desomorphine","UNII":"7OP86J5E33","Wikidata":"Q422163","XLogP":2.8}