{"Abbreviation":"","Aliases":["Cathinone","α-Amino-propiophenone","2-Aminopropiophenone","2-Amino-2-methylacetophenone","Abyssiniantea","Bathtabspeed","Looderstar","Ephedrane","Cath","Chat","Knat","Quat","African Tea","Cadillac Express","The C","Cathinone,","UR-1425","Propiophenone, 2-amino-","Ncgc00247670-01","1-aminoethyl phenyl ketone","CATHINONE","CAS_62258","STK895047","UR 1425","Ncgc00247670-04"],"Biological Half-Life":"The elimination half-life of cathinone is 1.5 +/- 0.8 hours","Boiling Point":"93 °C","CAS":"5265-18-9","ChEBI":"CHEBI:59332","ChEMBL":"CHEMBL1124","ChemicalClasses":["cathinone"],"Chirality":"racemic","Color/Form":"Pale yellow leaf from petroleum ether","Decomposition":"Hazardous decomposition products formed under fire conditions. - Carbon oxides, nitrogen oxides (NOx), Hydrogen chloride gas. /S(-)-Cathinone hydrochloride/","Erowid Experience Reports":[{"Author":"amphetacheese","Id":"58757","Title":"chagikhat"}],"Esters":[],"Formating":[],"HMDB ID":"HMDB0245024","HeavyAtomCount":11,"IUPACName":"2-amino-1-phenylpropan-1-one","InChI":"InChI=1S/C9H11NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7H,10H2,1H3","InChIKey":"PUAQLLVFLMYYJJ-UHFFFAOYSA-N","MeSH Pharmacological Classification":"A loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. They work by a variety of mechanisms, but usually not by direct excitation of neurons. The many drugs that have such actions as side effects to their main therapeutic use are not included here. (See all compounds classified as Central Nervous System Stimulants.)","Melting Point":"46.5 °C","MolecularFormula":"C\u003csub\u003e9\u003c/sub\u003eH\u003csub\u003e11\u003c/sub\u003eNO","MolecularWeight":"149.19 g/mol","Opticalactivity":"( + / - )","PubChemId":107786,"RefCount":3,"RefCur":"","References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Cathinone","Name":"Cathinone","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q27126636","Name":"Cathinone","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/107786","Name":"Cathinone","Sub":false}]},{"Name":"ChEMBL","Urls":[{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1124","Name":"Cathinone","Sub":false}]},{"Name":"ChEBI","Urls":[{"Link":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:59332","Name":"Cathinone","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=5265-18-9","Name":"Cathinone","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0245024","Name":"Cathinone","Sub":false}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/C22700","Name":"Cathinone","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/CX1Z9618HE","Name":"Cathinone","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID20860921","Name":"Cathinone","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 107786, Cathinone. Accessed July 13, 2025. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/107786\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/107786\u003c/a\u003e","U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Cathinone. UNII: CX1Z9618HE. Global Substance Registration System. Accessed July 13, 2025. \u003ca href=https://gsrs.ncats.nih.gov/ginas/app/beta/substances/CX1Z9618HE\u003ehttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/CX1Z9618HE\u003c/a\u003e"],"SMILES":"CC(C(=O)C1=CC=CC=C1)N","SaltData":[{"AcidCount":1,"AmineCount":1,"Formula":"Cl","Name":"hydrochloride","Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 99.254 49.848\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#3050f8\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h100v50H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"M53.836 41.181v-15.24M53.836 25.941l-13.198-7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M39.419 19.025V7.002M41.857 19.025V7.002\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"M39.419 7.002v6.011M41.857 7.002v6.011\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath d=\"m40.638 18.321-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m27.44 25.941-13.204-7.628M25.002 27.349l-10.766-6.22\"/\u003e\u003c/g\u003e\u003cpath d=\"m14.236 18.313-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m1.038 25.933.005 15.248M3.477 27.34l.004 12.434\"/\u003e\u003c/g\u003e\u003cpath d=\"m1.043 41.181 13.203 7.629\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m14.246 48.81 13.198-7.62M14.247 45.994l10.759-6.212\"/\u003e\u003c/g\u003e\u003cpath d=\"m27.44 25.941.004 15.249M53.836 25.941l10.045-5.799\" class=\"bond\"/\u003e\u003cpath fill=\"#ff0d0d\" stroke=\"none\" d=\"M42.897 3.078q0 .756-.256 1.328-.256.565-.756.881-.5.315-1.244.315-.756 0-1.262-.315-.506-.316-.756-.887-.244-.572-.244-1.334 0-.75.244-1.309.25-.566.756-.881T40.653.56q.732 0 1.232.316.5.309.756.875.256.565.256 1.327m-3.864 0q0 .923.387 1.459.393.53 1.221.53.839 0 1.22-.53.387-.536.387-1.459 0-.929-.387-1.452-.381-.524-1.208-.524-.834 0-1.227.524-.393.523-.393 1.452\" class=\"atom\"/\u003e\u003cg stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M68.975 20.771h-.72l-2.62-4.066h-.03l.03.595q.024.357.024.732v2.739h-.566v-4.9h.715l2.607 4.055h.03l-.018-.328-.024-.476q-.006-.262-.006-.482v-2.769h.578zM73.281 20.771h-.619v-2.286H70.15v2.286h-.613v-4.9h.613v2.072h2.512v-2.072h.619zM75.786 22.26h-1.943v-.3l.771-.778q.222-.222.372-.393.153-.175.232-.34.079-.167.079-.364 0-.243-.147-.368-.143-.128-.371-.128-.215 0-.379.075-.161.075-.329.207l-.193-.243q.172-.147.393-.247.225-.1.508-.1.41 0 .65.208.239.207.239.575 0 .228-.096.432-.093.2-.265.396-.168.197-.393.418l-.614.604v.018h1.486z\"/\u003e\u003c/g\u003e\u003cpath stroke=\"#3050f8\" d=\"m63.881 20.142-5.023 2.899\" class=\"hi\"/\u003e\u003c/g\u003e\u003cg class=\"mol\"\u003e\u003cg fill=\"#1ff01f\" stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M95.938 23.072q-.786 0-1.239.53-.452.524-.452 1.447 0 .911.417 1.447.422.529 1.268.529.321 0 .607-.053.292-.06.565-.143v.536q-.273.101-.565.149-.292.053-.697.053-.744 0-1.25-.309-.5-.31-.75-.876-.25-.571-.25-1.339 0-.744.268-1.31.274-.565.804-.881.529-.321 1.28-.321.779 0 1.351.286l-.244.523q-.226-.101-.506-.184-.274-.084-.607-.084m2.756 4.424h-.601v-5.215h.601zM93.03 27.496h-.619V25.21h-2.512v2.286h-.613v-4.9h.613v2.072h2.512v-2.072h.619z\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Title":"Cathinone hydrochloride","UNII":"272NNG64V6"}],"Salts":["hydrochloride"],"Solubility":"Very soluble in ether, ethanol","Stability/Shelf Life":"A primary concern with the forensic analysis of the khat plant (Catha edulis) has been the need to preserve the principle psychoactive component, cathinone, which converts to the less-active substance, cathine, after harvesting. The loss of cathinone has serious legal implications since it is a Schedule I controlled substance under federal regulations in the United States, while cathine is Schedule IV. A common misconception is that cathinone is highly unstable once the plant is harvested, and may be undetectable upon drying and prolonged storage. However, drying the plant material will preserve cathinone. Numerous seizures of a dried form of khat (referred to as \"graba\" in the United States) have been made in recent years, suggesting that drying the plant material is a viable approach to preserve khat evidence for both storage and reanalysis. A qualitative and quantitative study of the composition of khat samples seized as dried plant material has found the khat alkaloids to be relatively stable for a monitored period of 3 years, and cathinone has remained identifiable while stored at room temperature for over 10 years. Studies of green khat (received moist) have also determined that drying the moist leaves at either room temperature or by the application of heat are suitable methods to preserve cathinone in the dried material. These findings demonstrate that cathinone persists in dried khat for a time frame of several years, and simple drying techniques are an effective means to preserve seized khat evidence for long-term storage.","StereoisomerData":[{"Aliases":null,"PubChemId":null,"SMILES":"C[C@@H](N)C(=O)c1ccccc1","Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 76.346 49.848\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#3050f8\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h77v50H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M54.186 25.941h-.7M54.436 28.118h-1.2M54.686 30.295h-1.7M54.936 32.473h-2.2M55.186 34.65h-2.7M55.436 36.827h-3.2M55.686 39.004h-3.7M55.936 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d=\"M68.975 20.771h-.72l-2.62-4.066h-.03l.03.595q.024.357.024.732v2.739h-.566v-4.9h.715l2.607 4.055h.03l-.018-.328-.024-.476q-.006-.262-.006-.482v-2.769h.578zM73.281 20.771h-.619v-2.286H70.15v2.286h-.613v-4.9h.613v2.072h2.512v-2.072h.619zM75.786 22.26h-1.943v-.3l.771-.778q.222-.222.372-.393.153-.175.232-.34.079-.167.079-.364 0-.243-.147-.368-.143-.128-.371-.128-.215 0-.379.075-.161.075-.329.207l-.193-.243q.172-.147.393-.247.225-.1.508-.1.41 0 .65.208.239.207.239.575 0 .228-.096.432-.093.2-.265.396-.168.197-.393.418l-.614.604v.018h1.486z\"/\u003e\u003c/g\u003e\u003cpath fill=\"#ff0d0d\" stroke=\"none\" d=\"M42.897 3.078q0 .756-.256 1.328-.256.565-.756.881-.5.315-1.244.315-.756 0-1.262-.315-.506-.316-.756-.887-.244-.572-.244-1.334 0-.75.244-1.309.25-.566.756-.881T40.653.56q.732 0 1.232.316.5.309.756.875.256.565.256 1.327m-3.864 0q0 .923.387 1.459.393.53 1.221.53.839 0 1.22-.53.387-.536.387-1.459 0-.929-.387-1.452-.381-.524-1.208-.524-.834 0-1.227.524-.393.523-.393 1.452\" 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class=\"hi\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Title":"(S)-Cathinone","UNII":null}],"StereoisomerType":"enantiomer","Stereoisomers":["(R)-Cathinone","(S)-Cathinone"],"Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 76.346 49.848\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#3050f8\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h77v50H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"M53.836 41.181v-15.24M53.836 25.941l-13.198-7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M39.419 19.025V7.002M41.857 19.025V7.002\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"M39.419 7.002v6.011M41.857 7.002v6.011\" 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