{"Absorption, Distribution and Excretion":"Data for the absorption of butyrfentanyl are not readily available.","Aliases":["N-Phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)butanamide","Butyrfentanyl","Butyr-fentanyl","Butyryl fentanyl","Butyryl-fentanyl","N-(1-Phenethylpiperidin-4-yl)-N-phenylbutyramide","Nih-10486 free base","N-(1-phenylethyl)-4-piperidinyl)-N-phenylbutyramide","N-Phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]butanamide","Dtxcid20298482","Butanamide, N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]-","Butyrlfentanyl","N-phenyl-n-[1-(2-phenylethyl)piperidin-4-yl]butanamide","Chebi:233557","N-(1-phenethylpiperidin-4-yl)-N-phenylbutanamide","DEA No. 9822","Methyl-3-fentanyl","Butanamide, n-phenyl-n-(1-(2-phenylethyl)-4-piperidinyl)-","Butyranilide, N-(1-phenethyl-4-piperidyl)- (7CI,8CI); N-Phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]butanamide; Butyryl Fentanyl; Butyrfentanyl; Butyrylfentanyl; N-Phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]butanamide","N-butyrylfentanyl","N-butyramide fentanyl analog","Epitope ID:2272248","N-Phenyl-N-(1-phenethyl-4-piperidinyl)butanamide","Chembl4759342","Schembl18623773","BDBM641072","CS-D0505","Butyrylfentanyl, 1mg/ml in Methanol","Akos025243418","DB09173","N-(1-phenethyl-4-piperidyl)butyranilide","AS-48590","DB-027083","NS00017195","US20230399418, Compound Butyrylfentanyl","C22760","1-(2-phenylethyl)-4-(N,N-butyrylphenylamino)piperidine","N-(1-phenethyl-4-piperidyl)-n-phenyl-butanamide","N-Phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]butanamide #"],"Biological Half-Life":"Data for the half life of butyrfentanyl are not readily available.","CAS":"1169-70-6","ChemicalClasses":["phenethylpiperidine"],"Chirality":"achiral","Classes":["Opioid"],"DTXSID":"30347410","Drug Indication":"Butyrfentanyl was investigated as a potential opioid analgesic but is no longer used for this purpose. It is more often being used as a recreational drug.","Erowid Experience Reports":[{"Author":"SLY303","Id":109306,"Title":"Straight to the Point"}],"Esters":[],"European Community (EC) Number":"971-124-9","Formating":[],"HMDB ID":"HMDB0244419","HeavyAtomCount":26,"IUPACName":"N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]butanamide","InChI":"InChI=1S/C23H30N2O/c1-2-9-23(26)25(21-12-7-4-8-13-21)22-15-18-24(19-16-22)17-14-20-10-5-3-6-11-20/h3-8,10-13,22H,2,9,14-19H2,1H3","InChIKey":"QQOMYEQLWQJRKK-UHFFFAOYSA-N","MeSH Headers":[{"Id":"M000621909","Link":"https://id.nlm.nih.gov/mesh/M000621909.html","Name":"butyrfentanyl","Ref":27},{"Id":"DescTree","Link":"https://www.nlm.nih.gov/mesh/meshhome.html","Name":"MeSH Tree","Ref":29},{"Id":"PubMed from MeSH","Link":"https://www.nlm.nih.gov/mesh/meshhome.html","Name":null,"Ref":40}],"Mechanism of Action":"Butyrfentanyl is a µ opioid receptor agonist similar to fentanyl.","Metabolism/Metabolites":"Butyrfentanyl can be N-dealkylated to nor-butyrfentanyl by CYP3A4 and CYP2D6, hydroxylated to (ω-1)-hydroxy-butyrfentanyl by CYP3A4, 4'-hydroxylated to 4'-hydroxy-butyrfentanyl, hydroxylated to ω-hydroxy-butyrfentanyl bye CYP2D6 or CYP3A4, or hydroxylated to β-hydroxy-butyrfentanyl by CYP3A4. ω-hydroxy-butyrfentanyl is further metabolized to ω-carboxy-butyrfentanyl while 4'-hydroxy-butyrfentanyl is further metabolized to 4'-hydroxy-3'-methoxy-butyrfentanyl. Many of these metabolites may undergo further conjugation reactions with glucuronic acid or sulfate.","MolecularFormula":"C\u003csub\u003e23\u003c/sub\u003eH\u003csub\u003e30\u003c/sub\u003eN\u003csub\u003e2\u003c/sub\u003eO","MolecularWeight":"350.5 g/mol","Pharmacodynamics":"Data for the pharmacodynamics of butyrfentanyl are not readily available.","PubChemId":621174,"PubChemTitle":"N-Phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)butanamide","Reagents":[{"Colors":["#ffffff","#fd7322"],"Name":"Marquis"},{"Colors":["#ffffff","#f0d41d"],"Name":"Mecke"},{"Colors":["#f0d41d","#fd7322","#ff0000","#51240b","#f0d41d"],"Name":"Mandelin"},{"Colors":[],"Name":"Simon's"}],"Record Description":["Butyrfentanyl has no current legitimate clinical applications, however it is being sold as designer drug. Butyrfentanyl is illegal in the United Kingdom as it is a modification of fentanyl \"by replacement of the N-propionyl group by another acyl group\". One of the first mentions of this drug can be found in document written by The College on Problem of Drug Dependence, where it is mentioned as N-butyramide fentanyl analog. This document also states that the article describing its clinical effects (analgesic studies, m-, d-, k-Opioid receptor binding and in vitro measures of drug efficacy, antinociceptive and narcotic properties) was published in 1987. It is an agonist for the .MU.-opioid receptors.","WIKIPEDIA|FENTANYL ANALOGUES","Wikipedia|List of designer drugs|Sedatives|Opioids"],"Records":{"UNII":{"Impurities":[]}},"RefChem":"571886","RefCount":3,"RefCur":"","References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Butyrfentanyl","Name":"Butyrylfentanyl","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q15408419","Name":"Butyrylfentanyl","Sub":false}]},{"Name":"DrugBank","Urls":[{"Link":"https://go.drugbank.com/DB09173","Name":"Butyrylfentanyl","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/621174","Name":"Butyrylfentanyl","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=1169-70-6","Name":"Butyrylfentanyl","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0244419","Name":"Butyrylfentanyl","Sub":false}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/C22760","Name":"Butyrylfentanyl","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/07V1H7R6ZN","Name":"Butyrylfentanyl","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID30347410","Name":"Butyrylfentanyl","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 621174, Butyrylfentanyl. Accessed May 25, 2026. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/621174\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/621174\u003c/a\u003e","U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Butyrylfentanyl. UNII: 07V1H7R6ZN. Global Substance Registration System. Accessed May 25, 2026. \u003ca href=https://gsrs.ncats.nih.gov/ginas/app/beta/substances/07V1H7R6ZN\u003ehttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/07V1H7R6ZN\u003c/a\u003e"],"SMILES":"CCCC(=O)N(C1CCN(CC1)CCC2=CC=CC=C2)C3=CC=CC=C3","SaltData":[{"AcidCount":1,"Amine":"Butyrylfentanyl","AmineCount":1,"Formula":"Cl","Name":"hydrochloride","RName":"hydrochloride","Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 183.368 101.145\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#1ff01f\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h184v102H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"m159.422 46.758-13.198 7.62M146.224 54.378l-13.199-7.62M133.025 46.758l-13.198 7.62\" 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style=\"display:block\" viewBox=\"0 0 160.46 101.145\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#3050f8\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h161v102H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"m159.422 46.758-13.198 7.62M146.224 54.378l-13.199-7.62M133.025 46.758l-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M121.046 53.674v12.023M118.608 53.674v12.023\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"M121.046 65.697v-6.011M118.608 65.697v-6.011\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath d=\"m119.827 54.378-10.045-5.799M103.476 48.579l-10.045 5.799M93.431 54.378 80.228 46.75M80.228 46.75l-13.199 7.62M67.029 54.37l.004 11.398M70.187 71.44l10.05 5.807M80.237 77.247l13.199-7.62M93.431 54.378l.005 15.249M63.881 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