{"Abbreviation":[],"Adverse Effects":"Dermatotoxin - Skin burns.","Aliases":["Benzenemethanamine","Monobenzylamine","(Phenylmethyl)amine","α-Aminotoluene","(Aminomethyl)benzene","Moringine","Sumine 2005","Aminotoluene","omega-Aminotoluene","Sumine 2006","α Aminotoluene","RefChem:5598","202-854-1","1-phenylmethanamine","89551-24-6","N-Benzylamine","Phenylmethylamine","benzyl amine","a-Aminotoluene",".omega.-Aminotoluene","benzyl-amine","1utj","1utn","2bza","Toluene,α-amino"],"Boiling Point":"364.1 °","CAS":"100-46-9","ChEBI":"CHEBI:40538","ChEMBL":"CHEMBL522","ChemicalClasses":["benzylamine"],"Chirality":"achiral","Classes":["Antiemetic"],"Color/Form":"Colorless liquid","Decomposition":"When heated to decomposition it emits toxic fumes.","Density":"0.98 at 68 °F (USCG, 1999) - Less dense than water; will float g/cm\u003csup\u003e3\u003c/sup\u003e","EINECS":"202-854-1","Ecotoxicity Values":"LC50; Species: Pimephales promelas (fathead minnow); Conditions: flow through, 23.9 °C, pH 7.9, dissolved oxygen 6.9 mg/L, hardness 44.7 mg/L CaCO3, alkalinity 44.0 mg/L CaCO3; Concentration: 102 mg/L for 96 hr (confidence limit: 97.9-106 mg/L)","Esters":[],"European Community (EC) Number":"202-854-1","Flash Point":"168 °F (USCG, 1999)","Formating":[],"HMDB ID":"HMDB0033871","HeavyAtomCount":8,"IUPACName":"phenylmethanamine","InChI":"InChI=1S/C7H9N/c8-6-7-4-2-1-3-5-7/h1-5H,6,8H2","InChIKey":"WGQKYBSKWIADBV-UHFFFAOYSA-N","Interactions":"Semicarbazide-sensitive amine oxidase (SSAO) is highly expressed in adipose cells, and substrates of SSAO, such as benzylamine, in combination with low concentrations of vanadate strongly stimulate glucose transport and GLUT4 recruitment in 3T3-L1 and rat adipocytes. ...  Acute intravenous administration of these drugs enhanced glucose tolerance in nondiabetic rats and in streptozotocin (STZ)-induced diabetic rats. This occurred in the absence of changes in plasma insulin concentrations. However, the administration of benzylamine or vanadate alone did not improve glucose tolerance. The improvement caused by benzylamine plus vanadate was abolished when rats were pretreated with the SSAO-inhibitor semicarbazide. Chronic administration of benzylamine and vanadate exerted potent antidiabetic effects in STZ-induced diabetic rats. Although daily administration of vanadate alone (50 and 25 umol/kg/day i.p.) for 2 weeks had little or no effect on glycemia, vanadate plus benzylamine reduced hyperglycemia in diabetic rats, enhanced basal and insulin-stimulated glucose transport, and upregulated GLUT4 expression in isolated adipocytes...","LD50":[{"dosages":[{"amount":"600 mg/kg","route":"intraperitoneal"}],"organism":"Mouse"},{"dosages":[{"amount":"700 mg/kg","route":"oral"}],"organism":"Mammal (species unspecified)"}],"Melting Point":"-51 °F (USCG, 1999)","MolecularFormula":"C\u003csub\u003e7\u003c/sub\u003eH\u003csub\u003e9\u003c/sub\u003eN","MolecularWeight":"107.15 g/mol","Non-Human Toxicity Values":"LD50 Mouse ip 600 mg/kg","Odor":"Ammonia-like odor","Physical Description":"Benzylamine is a colorless to light yellow liquid with a strong odor of ammonia. Floats and mixes with water. (USCG, 1999)","PubChemId":7504,"RefCount":3,"RefCur":"","References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Benzylamine","Name":"Benzylamine","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q424000","Name":"Benzylamine","Sub":false}]},{"Name":"DrugBank","Urls":[{"Link":"https://go.drugbank.com/drugs/DB02464","Name":"Benzylamine","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/7504","Name":"Benzylamine","Sub":false}]},{"Name":"ChEMBL","Urls":[{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL522","Name":"Benzylamine","Sub":false}]},{"Name":"ChEBI","Urls":[{"Link":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:40538","Name":"Benzylamine","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=100-46-9","Name":"Benzylamine","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0033871","Name":"Benzylamine","Sub":false}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/C15562","Name":"Benzylamine","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/A1O31ROR09","Name":"Benzylamine","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID5021839","Name":"Benzylamine","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 7504, Benzylamine. Accessed September 16, 2025. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/7504\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/7504\u003c/a\u003e","U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Benzylamine. UNII: A1O31ROR09. Global Substance Registration System. Accessed September 16, 2025. \u003ca href=https://gsrs.ncats.nih.gov/ginas/app/beta/substances/A1O31ROR09\u003ehttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/A1O31ROR09\u003c/a\u003e"],"SMILES":"C1=CC=C(C=C1)CN","SaltData":[],"Salts":[],"Solubility":"Miscible in ethanol and diethyl ether. Very soluble in acetone. Soluble in benzene. Slightly soluble in chloroform.","StereoisomerData":[],"Stereoisomers":[],"Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 63.118 32.556\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#3050f8\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h64v33H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m1.038 8.654.005 15.24M3.477 10.062l.004 12.424\"/\u003e\u003c/g\u003e\u003cpath d=\"m1.038 8.654 13.191-7.616\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M27.425 8.662 14.229 1.038M24.987 10.07 14.229 3.854\"/\u003e\u003c/g\u003e\u003cpath d=\"m27.425 8.662.005 15.24\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m14.239 31.518 13.191-7.616M14.239 28.702l10.752-6.207\"/\u003e\u003c/g\u003e\u003cpath d=\"m1.043 23.894 13.196 7.624M27.425 8.662l13.191-7.615M40.616 1.047l10.037 5.795\" class=\"bond\"/\u003e\u003cg stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M55.747 11.112h-.72l-2.619-4.066h-.03l.03.595q.023.358.023.733v2.738h-.565V6.213h.714l2.608 4.054h.03l-.018-.328-.024-.476q-.006-.262-.006-.482V6.213h.577zM60.054 11.112h-.62V8.826h-2.512v2.286h-.613V6.213h.613v2.071h2.512V6.213h.62zM62.558 12.602h-1.943v-.3l.772-.779q.221-.222.371-.393.154-.175.232-.339.079-.168.079-.365 0-.243-.146-.368-.143-.128-.372-.128-.214 0-.379.075-.16.075-.328.207l-.193-.243q.171-.146.393-.246.225-.1.507-.1.411 0 .65.207t.239.575q0 .229-.096.432-.093.2-.264.397-.168.196-.393.418l-.615.603v.018h1.486z\"/\u003e\u003c/g\u003e\u003cpath stroke=\"#3050f8\" d=\"m50.653 6.842-5.018-2.898\" class=\"hi\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Subjective Effects":null,"Therapeutic Uses":"Benzylamine is found in Moringa oleifera, a plant used to treat diabetes in traditional medicine.","Title":"Benzylamine","UNII":"A1O31ROR09","Wikidata":"Q424000","Wikipedia":"Benzylamine","XLogP":1.1,"pH":"pH = 11.6 in water at a concentration of 100 g/L"}