{"ATC Code":"P - Antiparasitic products, insecticides and repellents","Abbreviation":"α-Cresol","Aliases":["benzyl alcohol","phenylcarbinol","Benzoyl alcohol","Benzenecarbinol","Phenylmethyl alcohol","(Hydroxymethyl)benzene","Phenolcarbinol","Alcool benzylique","Benzal alcohol","Methanol, phenyl-"],"Biological Half-Life":"The plasma half-life of benzyl alcohol administered as 2.5% solution in saline was found to be approximately 1.5 hr in dogs injected iv at doses of 52 and 105 mg/kg.","Boiling Point":"401 °","CAS":"100-51-6","ChEBI":"CHEBI:17987","ChEMBL":"CHEMBL720","ChemicalClasses":["alcohol"],"Chirality":"achiral","Classes":null,"Color/Form":"Water-white liquid","Decomposition":"When heated to decomposition it emits acrid smoke and fumes.","Density":"1.05 at 1515 °F (USCG, 1999) - Denser than water; will sink g/cm\u003csup\u003e3\u003c/sup\u003e","Drug Indication":"Ulesfia (benzyl alcohol) lotion is indicated for the topical treatment of head lice infestation in patients 6 months of age and older. Ulesfia Lotion does not have ovicidal activity.","Drug Warnings":"Common side effects of /Benzyl Alcohol Lotion, 5%/  include irritations of the skin, scalp, and eyes, and numbness at the site of application. As with all medications, it is important to use benzyl alcohol, 5%, as labeled to maximize benefits and minimize risks. The product should be applied only to the scalp or the hair attached to the scalp. It is not approved for use in children younger than six months. Use in premature infants could lead to serious respiratory, heart- or brain-related adverse events such as seizure, coma, or death.","DrugClasses":[],"EINECS":"202-859-9","Erowid Experience Reports":[],"European Community (EC) Number":"202-859-9","FDA Pharmacological Classification":"LKG8494WBH","Flash Point":"213 °F (NTP, 1992)","HMDB ID":"HMDB0003119","HeavyAtomCount":8,"Human Drugs":"Human drug -\u003e Discontinued","IUPACName":"phenylmethanol","Impurities":["benzaldehyde","cyclohexanemethanol"],"InChI":"InChI=1S/C7H8O/c8-6-7-4-2-1-3-5-7/h1-5,8H,6H2","InChIKey":"WVDDGKGOMKODPV-UHFFFAOYSA-N","MeSH Pharmacological Classification":"Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman\u0026apos;s The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate. (See all compounds classified as Anesthetics, Local.)","Melting Point":"4.5 °","MolecularFormula":"C\u003csub\u003e7\u003c/sub\u003eH\u003csub\u003e8\u003c/sub\u003eO","MolecularWeight":"108.14 g/mol","Odor":"Faint aromatic odor","Physical Description":"Benzyl alcohol appears as a clear colorless liquid with a pleasant odor. Slightly denser than water. Flash point 194 °F. Boiling point 401 °F. Contact may irritate skin, eyes, and mucous membranes. May be slightly toxic by ingestion. Used to make other chemicals.","PrevSalts":[],"PubChemId":244,"Record Description":["Benzyl alcohol appears as a clear colorless liquid with a pleasant odor. Slightly denser than water. Flash point 194 °F. Boiling point 401 °F. Contact may irritate skin, eyes, and mucous membranes. May be slightly toxic by ingestion. Used to make other chemicals.","Benzyl alcohol is an aromatic alcohol that consists of benzene bearing a single hydroxymethyl substituent. It has a role as a solvent, a metabolite, an antioxidant and a fragrance.","Benzyl alcohol is a metabolite found in or produced by Escherichia coli (strain K12, MG1655).","Benzyl alcohol is a Pediculicide.","Benzyl Alcohol has been reported in Camellia sinensis, Nymphaea rudgeana, and other organisms with data available.","BENZYL ALCOHOL is a small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 2009 and has 3 approved indications.","benzyl alcohol is a metabolite found in or produced by Saccharomyces cerevisiae.","A colorless liquid with a sharp burning taste and slight odor. It is used as a local anesthetic and to reduce pain associated with LIDOCAINE injection. Also, it is used in the manufacture of other benzyl compounds, as a pharmaceutic aid, and in perfumery and flavoring.","See also: Benzyl alcohol; zinc chloride (component of); Benzyl alcohol; pramoxine hydrochloride (component of); Anubis Barcelona (FDA NDC: 83021-839) (component of) ... View More ...","Benzyl alcohol is an aromatic alcohol that consists of benzene bearing a single hydroxymethyl substituent. It has a role as a solvent, a metabolite, an antioxidant and a fragrance."],"RefCount":3,"References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Benzyl alcohol","Name":"Benzylalcohol","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q52353","Name":"Benzylalcohol","Sub":false}]},{"Name":"DrugBank","Urls":[{"Link":"https://go.drugbank.com/drugs/DB06770","Name":"Benzylalcohol","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/244","Name":"Benzylalcohol","Sub":false}]},{"Name":"ChEMBL","Urls":[{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL720","Name":"Benzylalcohol","Sub":false}]},{"Name":"ChEBI","Urls":[{"Link":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:17987","Name":"Benzylalcohol","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=100-51-6","Name":"Benzylalcohol","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0003119","Name":"Benzylalcohol","Sub":false}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/C00556","Name":"Benzylalcohol","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/LKG8494WBH","Name":"Benzylalcohol","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID5020152","Name":"Benzylalcohol","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 244, Benzylalcohol. Accessed June 29, 2025. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/244\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/244\u003c/a\u003e","U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Benzylalcohol. UNII: LKG8494WBH. Global Substance Registration System. Accessed June 29, 2025. \u003ca href=https://gsrs.ncats.nih.gov/ginas/app/beta/substances/LKG8494WBH\u003ehttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/LKG8494WBH\u003c/a\u003e"],"SMILES":"C1=CC=C(C=C1)CO","Solubility":"10 to 50 mg/mL at 70 °F (NTP, 1992)","Stability/Shelf Life":"Oxidizes slowly, therefore remains stable for long time","StoreUNII":["LKG8494WBH"],"StructureBase64":"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","Subjective Effects":null,"Taste":"Sharp burning taste","Therapeutic Uses":"Anesthetics, Local; Pharmaceutic Aids","Title":"Benzylalcohol","UNII":"LKG8494WBH","Wikidata":"Q52353","Wikipedia":"Benzyl alcohol","XLogP":1.1,"pH":"A solution in water is neutral to litmus"}