{"ATC Code":"N02BB03","Abbreviation":[],"Aliases":["4-Aminoantipyrine","4-Aminophenazone","Metapirazone","Aminoantipyrine","4-Aminoantipyrene","Solvapyrin-A","Aminoantipyrin","Aminoazophene","Solnapyrin-A","Aminoazophenazone","4-AAP","4-Amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one","3H-Pyrazol-3-one, 4-amino-1,2-dihydro-1,5-dimethyl-2-phenyl-","4-Amino-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one","4 Aminophenazone","4 aminoantipyrine","RefChem:517541","4 Amino 1,5 Dimethyl 2 Phenyl 3H Pyrazolone","4-Amino-1,5-Dimethyl-2-Phenyl-3H-Pyrazolone","201-452-3","Antipyrine, 4-amino-","4-Amminoantipirina","1,5-Dimethyl-2-phenyl-4-aminopyrazoline","4-amino-1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one","4-AA"],"CAS":"83-07-8","ChEBI":"CHEBI:59026","ChEMBL":"CHEMBL1165011","ChemicalClasses":["aniline"],"Chirality":"achiral","Classes":["Analgesic","Antipyretics"],"EINECS":"201-452-3","Esters":[],"European Community (EC) Number":"201-452-3","Formating":[],"HMDB ID":"HMDB0246350","HeavyAtomCount":15,"IUPACName":"4-amino-1,5-dimethyl-2-phenylpyrazol-3-one","InChI":"InChI=1S/C11H13N3O/c1-8-10(12)11(15)14(13(8)2)9-6-4-3-5-7-9/h3-7H,12H2,1-2H3","InChIKey":"RLFWWDJHLFCNIJ-UHFFFAOYSA-N","LD50":[{"dosages":[{"amount":"1700 mg/kg","route":"oral"},{"amount":"1200 mg/kg","route":"intraperitoneal"}],"organism":"Rat"},{"dosages":[{"amount":"800 mg/kg","route":"oral"},{"amount":"270 mg/kg","route":"intraperitoneal"}],"organism":"Mouse"}],"MeSH Pharmacological Classification":"Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.","MolecularFormula":"C\u003csub\u003e11\u003c/sub\u003eH\u003csub\u003e13\u003c/sub\u003eN\u003csub\u003e3\u003c/sub\u003eO","MolecularWeight":"203.24 g/mol","PubChemId":2151,"RefCount":3,"RefCur":"","References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Ampyrone","Name":"Ampyrone","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q3599043","Name":"Ampyrone","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/2151","Name":"Ampyrone","Sub":false}]},{"Name":"ChEMBL","Urls":[{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1165011","Name":"Ampyrone","Sub":false}]},{"Name":"ChEBI","Urls":[{"Link":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:59026","Name":"Ampyrone","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=83-07-8","Name":"Ampyrone","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0246350","Name":"Ampyrone","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/0M0B7474RA","Name":"Ampyrone","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID8048860","Name":"Ampyrone","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 2151, Ampyrone. Accessed September 13, 2025. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/2151\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/2151\u003c/a\u003e","U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Ampyrone. UNII: 0M0B7474RA. Global Substance Registration System. Accessed September 13, 2025. \u003ca href=https://gsrs.ncats.nih.gov/ginas/app/beta/substances/0M0B7474RA\u003ehttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/0M0B7474RA\u003c/a\u003e"],"SMILES":"CC1=C(C(=O)N(N1C)C2=CC=CC=C2)N","SaltData":[{"AcidCount":1,"Amine":"Ampyrone","AmineCount":1,"Formula":"Cl","Name":"hydrochloride","Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 103.782 66.795\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#3050f8\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h104v67H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"m79.929 31.733-15.156-1.6\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m64.773 30.133-7.62-13.198M61.775 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