{"Abbreviation":"","Actives":["Chloral hydrate","Amphetamine"],"Aliases":["α-Methyl-N-(2,2,2-trichloroethylidene)benzeneethanamine","Amfecloral","Anfecloral","Amfecloral, (+)-","WZS9L0Z92R","6015XOA0BI","α-Methyl-N-(2,2,2-trichloroethylidene)phenethylamine","25394-63-2","71528-69-3","Amphechloral","Acutran; Amphecloral; α-Methyl-N-(2,2,2-trichloroethylidene)phenethylamine","1-Phenyl-N-(2,2,2-trichlorethyliden)-2-propylamin","Benzeneethanamine, α-methyl-N-(2,2,2-trichloroethylidene)-","Benzeneethanamine, α-methyl-N-(2,2,2-trichloroethylidene)-, (+)-","DB08924","D02926","Q4745975","α-Methyl-N-(2,2,2-trichloroethylidene)-benzeneethanamine","Acutran; Amphecloral; -Methyl-N-(2,2,2-trichloroethylidene)phenethylamine","Benzeneethanamine, α-methyl-n-(2,2,2-trichloroethylidene)-, (+)-","Benzeneethanamine, α-methyl-n-(2,2,2-trichloroethylidene)-"],"CAS":"5581-35-1","ChEBI":"CHEBI:135924","ChEMBL":"CHEMBL2105544","ChemicalClasses":["amphetamine"],"Chirality":"racemic","Classes":["Prodrug","Codrug"],"Drug Indication":"Used as an appetite suppressant.","Erowid Experience Reports":null,"Esters":[],"Formating":[],"HeavyAtomCount":15,"IUPACName":"2,2,2-trichloro-N-(1-phenylpropan-2-yl)ethanimine","InChI":"InChI=1S/C11H12Cl3N/c1-9(15-8-11(12,13)14)7-10-5-3-2-4-6-10/h2-6,8-9H,7H2,1H3","InChIKey":"VBZDETYCYXPOAK-UHFFFAOYSA-N","MolecularFormula":"C\u003csub\u003e11\u003c/sub\u003eH\u003csub\u003e12\u003c/sub\u003eCl\u003csub\u003e3\u003c/sub\u003eN","MolecularWeight":"264.6 g/mol","Opticalactivity":"( - )","PubChemId":21759,"RefCount":3,"RefCur":"","References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Amfecloral","Name":"Amphecloral","Sub":false}]},{"Name":"DrugBank","Urls":[{"Link":"https://go.drugbank.com/drugs/DB08924","Name":"Amphecloral","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/21759","Name":"Amphecloral","Sub":false}]},{"Name":"ChEMBL","Urls":[{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2105544","Name":"Amphecloral","Sub":false}]},{"Name":"ChEBI","Urls":[{"Link":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:135924","Name":"Amphecloral","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=5581-35-1","Name":"Amphecloral","Sub":false}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/D02926","Name":"Amphecloral","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/S0DYI19OEX","Name":"Amphecloral","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID00863571","Name":"Amphecloral","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 21759, Amphecloral. Accessed July 19, 2025. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/21759\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/21759\u003c/a\u003e","U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Amphecloral. UNII: S0DYI19OEX. Global Substance Registration System. Accessed July 19, 2025. \u003ca href=https://gsrs.ncats.nih.gov/ginas/app/beta/substances/S0DYI19OEX\u003ehttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/S0DYI19OEX\u003c/a\u003e"],"SMILES":"CC(CC1=CC=CC=C1)N=CC(Cl)(Cl)Cl","SaltData":[],"Salts":[],"StereoisomerData":[{"Aliases":null,"PubChemId":null,"SMILES":"C[C@H](Cc1ccccc1)/N=C/C(Cl)(Cl)Cl","Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 110.44 47.892\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#1ff01f\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h111v48H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M54.186 23.986h-.7M54.436 26.163h-1.2M54.686 28.34h-1.7M54.936 30.517h-2.2M55.186 32.694h-2.7M55.436 34.871h-3.2M55.686 37.049h-3.7M55.936 39.226h-4.2\"/\u003e\u003c/g\u003e\u003cpath d=\"m53.836 23.986-13.198-7.62M40.638 16.366l-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m27.44 23.986-13.204-7.629M25.002 25.393l-10.766-6.22\"/\u003e\u003c/g\u003e\u003cpath d=\"m14.236 16.357-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m1.038 23.977.005 15.249M3.477 25.385l.004 12.433\"/\u003e\u003c/g\u003e\u003cpath d=\"m1.043 39.226 13.203 7.628\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m14.246 46.854 13.198-7.62M14.247 44.038l10.759-6.211\"/\u003e\u003c/g\u003e\u003cpath d=\"m27.44 23.986.004 15.248M53.836 23.986l10.045-5.8\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m70.187 18.186 10.045 5.8M68.968 20.298l8.826 5.096\"/\u003e\u003cpath stroke=\"#3050f8\" d=\"m70.187 18.186 5.022 2.9M68.968 20.298l4.413 2.548\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath d=\"m80.232 23.986 13.199-7.62M93.431 16.366l-6.62-11.465M93.431 16.366l10.241-5.913M93.431 16.366l5.776 10.004\" class=\"bond\"/\u003e\u003cpath fill=\"#3050f8\" stroke=\"none\" d=\"M68.975 18.815h-.72l-2.62-4.066h-.03l.03.596q.024.357.024.732v2.738h-.566v-4.899h.715l2.607 4.054h.03l-.018-.327-.024-.477q-.006-.262-.006-.482v-2.768h.578z\" class=\"atom\"/\u003e\u003cpath stroke=\"none\" d=\"M83.355 1.352q-.786 0-1.239.53-.452.523-.452 1.446 0 .911.417 1.447.422.53 1.268.53.321 0 .607-.054.292-.059.565-.143v.536q-.273.101-.565.149-.292.053-.697.053-.744 0-1.25-.309-.5-.31-.75-.875-.25-.572-.25-1.34 0-.744.268-1.309.274-.566.804-.881.529-.322 1.28-.322.779 0 1.351.286l-.244.524q-.226-.102-.506-.185-.274-.083-.607-.083m2.756 4.423h-.601V.56h.601zM107.123 6.769q-.786 0-1.238.53-.453.524-.453 1.447 0 .911.417 1.446.423.53 1.268.53.321 0 .607-.053.292-.06.566-.143v.535q-.274.102-.566.149-.291.054-.696.054-.744 0-1.25-.31-.5-.309-.751-.875-.25-.571-.25-1.339 0-.744.268-1.31.274-.565.804-.881.53-.321 1.28-.321.78 0 1.351.285l-.244.524q-.226-.101-.506-.184-.274-.084-.607-.084m2.757 4.423h-.602V5.977h.602zM101.545 27.587q-.786 0-1.238.53-.453.524-.453 1.447 0 .911.417 1.447.422.529 1.268.529.321 0 .607-.053.292-.06.566-.143v.536q-.274.101-.566.149-.292.053-.696.053-.745 0-1.251-.309-.5-.31-.75-.876-.25-.571-.25-1.339 0-.744.268-1.31.274-.565.804-.881.53-.321 1.28-.321.78 0 1.351.286l-.244.523q-.226-.101-.506-.184-.274-.084-.607-.084m2.756 4.424h-.601v-5.215h.601z\" class=\"atom\"/\u003e\u003cpath stroke=\"#3050f8\" d=\"m63.881 18.186-5.023 2.9\" class=\"hi\"/\u003e\u003cpath stroke=\"#1ff01f\" d=\"m86.811 4.901 3.31 5.732M103.672 10.453l-5.12 2.956M99.207 26.37l-2.888-5.002\" class=\"hi\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Title":"(R)-Amphecloral","UNII":null},{"Aliases":null,"PubChemId":null,"SMILES":"C[C@@H](Cc1ccccc1)/N=C/C(Cl)(Cl)Cl","Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 110.44 47.892\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#1ff01f\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h111v48H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath fill=\"#000\" stroke=\"none\" d=\"M54.186 23.986h-.7l-1.75 15.24h4.2z\" class=\"bond\"/\u003e\u003cpath d=\"m53.836 23.986-13.198-7.62M40.638 16.366l-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m27.44 23.986-13.204-7.629M25.002 25.393l-10.766-6.22\"/\u003e\u003c/g\u003e\u003cpath d=\"m14.236 16.357-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m1.038 23.977.005 15.249M3.477 25.385l.004 12.433\"/\u003e\u003c/g\u003e\u003cpath d=\"m1.043 39.226 13.203 7.628\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m14.246 46.854 13.198-7.62M14.247 44.038l10.759-6.211\"/\u003e\u003c/g\u003e\u003cpath d=\"m27.44 23.986.004 15.248M53.836 23.986l10.045-5.8\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m70.187 18.186 10.045 5.8M68.968 20.298l8.826 5.096\"/\u003e\u003cpath stroke=\"#3050f8\" d=\"m70.187 18.186 5.022 2.9M68.968 20.298l4.413 2.548\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath d=\"m80.232 23.986 13.199-7.62M93.431 16.366l-6.62-11.465M93.431 16.366l10.241-5.913M93.431 16.366l5.776 10.004\" class=\"bond\"/\u003e\u003cpath fill=\"#3050f8\" stroke=\"none\" d=\"M68.975 18.815h-.72l-2.62-4.066h-.03l.03.596q.024.357.024.732v2.738h-.566v-4.899h.715l2.607 4.054h.03l-.018-.327-.024-.477q-.006-.262-.006-.482v-2.768h.578z\" class=\"atom\"/\u003e\u003cpath stroke=\"none\" d=\"M83.355 1.352q-.786 0-1.239.53-.452.523-.452 1.446 0 .911.417 1.447.422.53 1.268.53.321 0 .607-.054.292-.059.565-.143v.536q-.273.101-.565.149-.292.053-.697.053-.744 0-1.25-.309-.5-.31-.75-.875-.25-.572-.25-1.34 0-.744.268-1.309.274-.566.804-.881.529-.322 1.28-.322.779 0 1.351.286l-.244.524q-.226-.102-.506-.185-.274-.083-.607-.083m2.756 4.423h-.601V.56h.601zM107.123 6.769q-.786 0-1.238.53-.453.524-.453 1.447 0 .911.417 1.446.423.53 1.268.53.321 0 .607-.053.292-.06.566-.143v.535q-.274.102-.566.149-.291.054-.696.054-.744 0-1.25-.31-.5-.309-.751-.875-.25-.571-.25-1.339 0-.744.268-1.31.274-.565.804-.881.53-.321 1.28-.321.78 0 1.351.285l-.244.524q-.226-.101-.506-.184-.274-.084-.607-.084m2.757 4.423h-.602V5.977h.602zM101.545 27.587q-.786 0-1.238.53-.453.524-.453 1.447 0 .911.417 1.447.422.529 1.268.529.321 0 .607-.053.292-.06.566-.143v.536q-.274.101-.566.149-.292.053-.696.053-.745 0-1.251-.309-.5-.31-.75-.876-.25-.571-.25-1.339 0-.744.268-1.31.274-.565.804-.881.53-.321 1.28-.321.78 0 1.351.286l-.244.523q-.226-.101-.506-.184-.274-.084-.607-.084m2.756 4.424h-.601v-5.215h.601z\" class=\"atom\"/\u003e\u003cpath stroke=\"#3050f8\" d=\"m63.881 18.186-5.023 2.9\" class=\"hi\"/\u003e\u003cpath stroke=\"#1ff01f\" d=\"m86.811 4.901 3.31 5.732M103.672 10.453l-5.12 2.956M99.207 26.37l-2.888-5.002\" class=\"hi\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Title":"(S)-Amphecloral","UNII":null}],"StereoisomerType":"diastereomer","Stereoisomers":["(R)-Amphecloral","(S)-Amphecloral"],"Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 110.44 47.892\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#1ff01f\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h111v48H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"M53.836 39.226v-15.24M53.836 23.986l-13.198-7.62M40.638 16.366l-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m27.44 23.986-13.204-7.629M25.002 25.393l-10.766-6.22\"/\u003e\u003c/g\u003e\u003cpath d=\"m14.236 16.357-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m1.038 23.977.005 15.249M3.477 25.385l.004 12.433\"/\u003e\u003c/g\u003e\u003cpath d=\"m1.043 39.226 13.203 7.628\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m14.246 46.854 13.198-7.62M14.247 44.038l10.759-6.211\"/\u003e\u003c/g\u003e\u003cpath d=\"m27.44 23.986.004 15.248M53.836 23.986l10.045-5.8\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m70.187 18.186 10.045 5.8M68.968 20.298l8.826 5.096\"/\u003e\u003cpath stroke=\"#3050f8\" d=\"m70.187 18.186 5.022 2.9M68.968 20.298l4.413 2.548\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath fill=\"none\" d=\"M80.232 23.986c.239.412.889.586 1.302.348.412-.238.586-.888.348-1.301s-.064-1.063.349-1.301c.412-.238 1.063-.064 1.301.349.238.412.889.586 1.301.348.413-.238.587-.888.349-1.301s-.064-1.063.348-1.301c.413-.238 1.063-.064 1.302.349.238.412.888.586 1.301.348s.586-.888.348-1.301-.063-1.063.349-1.301 1.063-.064 1.301.349c.238.412.889.586 1.301.348.413-.238.587-.888.349-1.301s-.064-1.063.349-1.301c.412-.238 1.063-.064 1.301.349\" class=\"bond\"/\u003e\u003cpath d=\"m93.431 16.366-6.62-11.465M93.431 16.366l10.241-5.913M93.431 16.366l5.776 10.004\" class=\"bond\"/\u003e\u003cpath fill=\"#3050f8\" stroke=\"none\" d=\"M68.975 18.815h-.72l-2.62-4.066h-.03l.03.596q.024.357.024.732v2.738h-.566v-4.899h.715l2.607 4.054h.03l-.018-.327-.024-.477q-.006-.262-.006-.482v-2.768h.578z\" class=\"atom\"/\u003e\u003cpath stroke=\"none\" d=\"M83.355 1.352q-.786 0-1.239.53-.452.523-.452 1.446 0 .911.417 1.447.422.53 1.268.53.321 0 .607-.054.292-.059.565-.143v.536q-.273.101-.565.149-.292.053-.697.053-.744 0-1.25-.309-.5-.31-.75-.875-.25-.572-.25-1.34 0-.744.268-1.309.274-.566.804-.881.529-.322 1.28-.322.779 0 1.351.286l-.244.524q-.226-.102-.506-.185-.274-.083-.607-.083m2.756 4.423h-.601V.56h.601zM107.123 6.769q-.786 0-1.238.53-.453.524-.453 1.447 0 .911.417 1.446.423.53 1.268.53.321 0 .607-.053.292-.06.566-.143v.535q-.274.102-.566.149-.291.054-.696.054-.744 0-1.25-.31-.5-.309-.751-.875-.25-.571-.25-1.339 0-.744.268-1.31.274-.565.804-.881.53-.321 1.28-.321.78 0 1.351.285l-.244.524q-.226-.101-.506-.184-.274-.084-.607-.084m2.757 4.423h-.602V5.977h.602zM101.545 27.587q-.786 0-1.238.53-.453.524-.453 1.447 0 .911.417 1.447.422.529 1.268.529.321 0 .607-.053.292-.06.566-.143v.536q-.274.101-.566.149-.292.053-.696.053-.745 0-1.251-.309-.5-.31-.75-.876-.25-.571-.25-1.339 0-.744.268-1.31.274-.565.804-.881.53-.321 1.28-.321.78 0 1.351.286l-.244.523q-.226-.101-.506-.184-.274-.084-.607-.084m2.756 4.424h-.601v-5.215h.601z\" class=\"atom\"/\u003e\u003cpath stroke=\"#3050f8\" d=\"m63.881 18.186-5.023 2.9\" class=\"hi\"/\u003e\u003cpath stroke=\"#1ff01f\" d=\"m86.811 4.901 3.31 5.732M103.672 10.453l-5.12 2.956M99.207 26.37l-2.888-5.002\" class=\"hi\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Subjective Effects":null,"Title":"Amphecloral","UNII":"S0DYI19OEX","Wikipedia":"Amfecloral","XLogP":4.1}