{"Abbreviation":"","Aliases":["Alifedrina","Alifedrinum","1-cyclohexyl-3-(((1R,2S)-1-hydroxy-1-phenylpropan-2-yl)amino)propan-1-one","1-Cyclohexyl-3-(((αS,βR)-β-hydroxy-α-methylphenethyl)amino)-1-propanone","1-Propanone, 1-cyclohexyl-3-((2-hydroxy-1-methyl-2-phenylethyl)amino)-, (R-(R*,S*))-","1-Cyclohexyl-3-(((αs,βr)-β-hydroxy-α-methylphenethyl)amino)-1-propanone"],"CAS":"78756-61-3","ChEMBL":"CHEMBL2104023","ChemicalClasses":["phenylethanolamine"],"Chirality":"absolute","Classes":["Sympathomimetic"],"Dosing Info":[],"DrugClasses":[],"DurationOfAction":"","EliminationHalfLife":"","FullSalts":["Alifedrine hydrochloride"],"HeavyAtomCount":21,"IUPACName":"1-cyclohexyl-3-[[(1R,2S)-1-hydroxy-1-phenylpropan-2-yl]amino]propan-1-one","InChI":"InChI=1S/C18H27NO2/c1-14(18(21)16-10-6-3-7-11-16)19-13-12-17(20)15-8-4-2-5-9-15/h3,6-7,10-11,14-15,18-19,21H,2,4-5,8-9,12-13H2,1H3/t14-,18-/m0/s1","InChIKey":"UEELVIXXTBPOCF-KSSFIOAISA-N","MeSH Pharmacological Classification":"Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE). (See all compounds classified as Cardiotonic Agents.)","MolecularFormula":"C\u003csub\u003e18\u003c/sub\u003eH\u003csub\u003e27\u003c/sub\u003eNO\u003csub\u003e2\u003c/sub\u003e","MolecularWeight":"289.4 g/mol","Opticalactivity":"UNSPECIFIED","PrevSalts":["hydrochloride"],"PubChemId":51719,"References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Alifedrine","Name":"Alifedrine","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q15633918","Name":"Alifedrine","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/51719","Name":"Alifedrine","Sub":false}]},{"Name":"ChEMBL","Urls":[{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2104023","Name":"Alifedrine","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=78756-61-3","Name":"Alifedrine","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/K2PM66M0VQ","Name":"Alifedrine","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID00229274","Name":"Alifedrine","Sub":false}]}],"SMILES":"C[C@@H]([C@@H](C1=CC=CC=C1)O)NCCC(=O)C2CCCCC2","Salts":["hydrochloride"],"SaltsAcidCount":[1],"SaltsAmineCount":[1],"SaltsUNII":["N0O8SN3IN6"],"Scheduling":[],"StoreUNII":["K2PM66M0VQ"],"StructureBase64":"<svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" height="55.433mm" version="1.2" viewBox="0 0 147.267 55.433" width="147.267mm">
      
    <desc>Generated by the Chemistry Development Kit (http://github.com/cdk)</desc>
      
    <g fill="#FF0D0D" stroke="#000000" stroke-linecap="round" stroke-linejoin="round" stroke-width=".7">
            
        <rect fill="#FFFFFF" height="56.0" stroke="none" width="148.0" x=".0" y=".0"/>
            
        <g class="mol" id="mol1">
                  
            <path class="bond" d="M54.186 31.527h-.7l-1.75 15.24h2.1h2.1z" fill="#000000" id="mol1bnd1" stroke="none"/>
                  
            <line class="bond" id="mol1bnd2" x1="53.836" x2="40.638" y1="31.527" y2="23.907"/>
                  
            <line class="bond" id="mol1bnd3" x1="40.638" x2="27.44" y1="23.907" y2="31.527"/>
                  
            <g class="bond" id="mol1bnd4">
                        
                <line x1="27.44" x2="14.236" y1="31.527" y2="23.898"/>
                        
                <line x1="25.002" x2="14.236" y1="32.934" y2="26.714"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd5" x1="14.236" x2="1.038" y1="23.898" y2="31.518"/>
                  
            <g class="bond" id="mol1bnd6">
                        
                <line x1="1.038" x2="1.043" y1="31.518" y2="46.767"/>
                        
                <line x1="3.477" x2="3.481" y1="32.926" y2="45.359"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd7" x1="1.043" x2="14.246" y1="46.767" y2="54.395"/>
                  
            <g class="bond" id="mol1bnd8">
                        
                <line x1="14.246" x2="27.444" y1="54.395" y2="46.775"/>
                        
                <line x1="14.247" x2="25.006" y1="51.579" y2="45.368"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd9" x1="27.44" x2="27.444" y1="31.527" y2="46.775"/>
                  
            <path class="bond" d="M40.288 23.907h.7l1.3 -11.319h-1.65h-1.65z" fill="#000000" id="mol1bnd10" stroke="none"/>
                  
            <line class="bond" id="mol1bnd11" x1="53.836" x2="63.881" y1="31.527" y2="25.727"/>
                  
            <line class="bond" id="mol1bnd12" x1="70.187" x2="80.232" y1="25.727" y2="31.527"/>
                  
            <line class="bond" id="mol1bnd13" x1="80.232" x2="93.431" y1="31.527" y2="23.907"/>
                  
            <line class="bond" id="mol1bnd14" x1="93.431" x2="106.629" y1="23.907" y2="31.527"/>
                  
            <g class="bond" id="mol1bnd15">
                        
                <line x1="107.848" x2="107.848" y1="30.823" y2="42.845"/>
                        
                <line x1="105.41" x2="105.41" y1="30.823" y2="42.845"/>
                      
                <line class="hi" stroke="#FF0D0D" x1="107.848" x2="107.848" y1="42.845" y2="36.834"/>
                <line class="hi" stroke="#FF0D0D" x1="105.41" x2="105.41" y1="42.845" y2="36.834"/>
            </g>
                  
            <line class="bond" id="mol1bnd16" x1="106.629" x2="119.827" y1="31.527" y2="23.907"/>
                  
            <line class="bond" id="mol1bnd17" x1="119.827" x2="133.03" y1="23.907" y2="31.535"/>
                  
            <line class="bond" id="mol1bnd18" x1="133.03" x2="146.228" y1="31.535" y2="23.915"/>
                  
            <line class="bond" id="mol1bnd19" x1="146.228" x2="146.224" y1="23.915" y2="8.667"/>
                  
            <line class="bond" id="mol1bnd20" x1="146.224" x2="133.02" y1="8.667" y2="1.038"/>
                  
            <line class="bond" id="mol1bnd21" x1="133.02" x2="119.822" y1="1.038" y2="8.658"/>
                  
            <line class="bond" id="mol1bnd22" x1="119.827" x2="119.822" y1="23.907" y2="8.658"/>
                  
            <g class="atom" id="mol1atm10">
                        
                <path d="M42.897 8.664q-.0 .756 -.256 1.327q-.256 .566 -.756 .881q-.5 .316 -1.244 .316q-.756 -.0 -1.262 -.316q-.506 -.315 -.756 -.887q-.244 -.571 -.244 -1.333q-.0 -.75 .244 -1.31q.25 -.565 .756 -.881q.506 -.315 1.274 -.315q.732 -.0 1.232 .315q.5 .31 .756 .875q.256 .566 .256 1.328zM39.033 8.664q.0 .922 .387 1.458q.393 .53 1.221 .53q.839 .0 1.22 -.53q.387 -.536 .387 -1.458q.0 -.929 -.387 -1.453q-.381 -.524 -1.208 -.524q-.834 .0 -1.227 .524q-.393 .524 -.393 1.453z" stroke="none"/>
                        
                <path d="M47.203 11.116h-.619v-2.286h-2.512v2.286h-.613v-4.899h.613v2.072h2.512v-2.072h.619v4.899z" stroke="none"/>
                      
            </g>
                  
            <g class="atom" id="mol1atm11">
                        
                <path d="M68.975 26.356h-.72l-2.62 -4.066h-.03q.012 .239 .03 .596q.024 .357 .024 .732v2.738h-.566v-4.899h.715l2.607 4.054h.03q-.006 -.107 -.018 -.327q-.012 -.221 -.024 -.477q-.006 -.262 -.006 -.482v-2.768h.578v4.899z" fill="#3050F8" stroke="none"/>
                        
                <path d="M68.838 20.895h-.619v-2.286h-2.512v2.286h-.614v-4.899h.614v2.072h2.512v-2.072h.619v4.899z" fill="#3050F8" stroke="none"/>
                      
            </g>
                  
            <path class="atom" d="M108.888 46.764q.0 .756 -.256 1.327q-.256 .566 -.756 .881q-.5 .316 -1.244 .316q-.756 -.0 -1.262 -.316q-.506 -.315 -.756 -.887q-.244 -.571 -.244 -1.333q-.0 -.75 .244 -1.31q.25 -.565 .756 -.881q.506 -.315 1.274 -.315q.732 -.0 1.232 .315q.5 .31 .756 .875q.256 .566 .256 1.328zM105.025 46.764q-.0 .922 .386 1.458q.393 .53 1.221 .53q.839 .0 1.22 -.53q.387 -.536 .387 -1.458q.0 -.929 -.387 -1.453q-.381 -.524 -1.208 -.524q-.834 .0 -1.227 .524q-.392 .524 -.392 1.453z" id="mol1atm15" stroke="none"/>
                
            <line class="hi" id="mol1bnd11" stroke="#3050F8" x1="63.881" x2="58.8585" y1="25.727" y2="28.627000000000002"/>
            <line class="hi" id="mol1bnd11" stroke="#3050F8" x1="63.881" x2="58.8585" y1="25.727" y2="28.627000000000002"/>
            <line class="hi" id="mol1bnd12" stroke="#3050F8" x1="70.187" x2="75.20949999999999" y1="25.727" y2="28.627000000000002"/>
            <line class="hi" id="mol1bnd12" stroke="#3050F8" x1="70.187" x2="75.20949999999999" y1="25.727" y2="28.627000000000002"/>
        </g>
          
    </g>
    
</svg>
","Title":"Alifedrine","UNII":"K2PM66M0VQ","Wikidata":"Q15633918","Wikipedia":"Alifedrine","XLogP":2.8}