{"Abbreviation":"Ala","Aliases":["DL-ALANINE","DL-2-Aminopropionic acid","D,L-Alanine","DL-2-Aminopropanoic acid","AI3-08908","CCRIS 8596","Dl-alanine","Fema no. 3818","DLαAlanine","D,LAlanine"],"CAS":"302-72-7","ChEBI":"CHEBI:16449","ChEMBL":"CHEMBL12198","ChemicalClasses":["amino acid"],"Chirality":"racemic","ChiralityAminoAcid":true,"Classes":null,"Dosing Info":[],"DrugClasses":[],"EINECS":"206-126-4","Esters":["acetate","benzoate"],"European Community (EC) Number":"206-126-4","HMDB ID":"HMDB0062251","HeavyAtomCount":6,"IUPACName":"2-aminopropanoic acid","InChI":"InChI=1S/C3H7NO2/c1-2(4)3(5)6/h2H,4H2,1H3,(H,5,6)","InChIKey":"QNAYBMKLOCPYGJ-UHFFFAOYSA-N","MolecularFormula":"C\u003csub\u003e3\u003c/sub\u003eH\u003csub\u003e7\u003c/sub\u003eNO\u003csub\u003e2\u003c/sub\u003e","MolecularWeight":"89.09 g/mol","Opticalactivity":"( + / - )","Physical Description":"Solid; [Merck Index] White powder; [Sigma-Aldrich MSDS]","PrevSalts":[],"PubChemId":602,"Record Description":["Alanine is an alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2. It has a role as a fundamental metabolite. It is functionally related to a propionic acid. It is a conjugate base of an alaninium. It is a conjugate acid of an alaninate. It is a tautomer of an alanine zwitterion.","DL-Alanine has been reported in Drosophila melanogaster, Populus tremula, and other organisms with data available.","DL-Alanine is a racemic mixture of alanine, a non-essential alpha-amino acid. Alanine is one of the most common residues for protein synthesis and is involved in the metabolism of tryptophan and vitamin pyridoxine. Furthermore, alanine is an important source of energy for muscles and central nervous system. It strengthens the immune system, helps in the metabolism of sugars and organic acids, and displays a cholesterol-reducing effect in animals.","ALANINE is a small molecule drug with a maximum clinical trial phase of III (across all indications) and has 3 investigational indications.","See also: Alanine (annotation moved to); D-Alanine (annotation moved to).","Alanine is an alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2. It has a role as a fundamental metabolite. It is functionally related to a propionic acid. It is a conjugate base of an alaninium. It is a conjugate acid of an alaninate. It is a tautomer of an alanine zwitterion."],"References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Alanine","Name":"Alanine","Sub":false},{"Link":"https://en.wikipedia.org/wiki/Α-alanine","Name":"L-Alanine","Sub":true}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q27101911","Name":"Alanine","Sub":false},{"Link":"https://www.wikidata.org/wiki/Q106345495","Name":"D-Alanine","Sub":true},{"Link":"https://www.wikidata.org/wiki/Q106345485","Name":"L-Alanine","Sub":true}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/602","Name":"Alanine","Sub":false},{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/71080","Name":"D-Alanine","Sub":true},{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/5950","Name":"L-Alanine","Sub":true}]},{"Name":"ChEMBL","Urls":[{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL12198","Name":"Alanine","Sub":false},{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL66693","Name":"D-Alanine","Sub":true},{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL279597","Name":"L-Alanine","Sub":true}]},{"Name":"ChEBI","Urls":[{"Link":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:16449","Name":"Alanine","Sub":false},{"Link":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:15570","Name":"D-Alanine","Sub":true},{"Link":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:16977","Name":"L-Alanine","Sub":true}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=302-72-7","Name":"Alanine","Sub":false},{"Link":"https://commonchemistry.cas.org/detail?cas_rn=338-69-2","Name":"D-Alanine","Sub":true},{"Link":"https://commonchemistry.cas.org/detail?cas_rn=56-41-7","Name":"L-Alanine","Sub":true}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0062251","Name":"Alanine","Sub":false},{"Link":"https://hmdb.ca/metabolites/HMDB0001310","Name":"D-Alanine","Sub":true},{"Link":"https://hmdb.ca/metabolites/HMDB0000161","Name":"L-Alanine","Sub":true}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/C01401","Name":"Alanine","Sub":false},{"Link":"https://www.kegg.jp/entry/C00133","Name":"D-Alanine","Sub":true},{"Link":"https://www.kegg.jp/entry/C00041","Name":"L-Alanine","Sub":true}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/1FU7983T0U","Name":"Alanine","Sub":false},{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/E3UDS4613U","Name":"D-Alanine","Sub":true},{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/OF5P57N2ZX","Name":"L-Alanine","Sub":true}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID6031255","Name":"Alanine","Sub":false},{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID3045649","Name":"D-Alanine","Sub":true},{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID20873899","Name":"L-Alanine","Sub":true}]}],"SMILES":"CC(C(=O)O)N","Solubility":"Solublein water","StereoisomerRacemic":"DL-Alanine","Stereoisomers":["D-Alanine","L-Alanine","DL-Alanine"],"StereoisomersUNII":["E3UDS4613U","OF5P57N2ZX",""],"StoreUNII":["1FU7983T0U"],"StructureBase64":"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","Title":"Alanine","UNII":"1FU7983T0U","Wikidata":"Q27101911","Wikipedia":"Alanine","XLogP":-3}