{"Abbreviation":"4-MTA","Aliases":["4-MTA","p-Methylthioamphetamine","Benzeneethanamine, α-methyl-4-(methylthio)-","α-Methyl-p-(methylthio)phenethylamine","Flatliners","Golden eagle","P-1882","4-Methylthioamphetamin","FLATLINERS","2-Amino-1-(4-methylthiophenyl)propane","Methylthioamfetamine","1-(6-(methylthio)naphthalen-2-yl)propan-2-amine","α-Methyl-4-methylthiophenethylamine","1-[4-(Methylsulfanyl)phenyl]propan-2-amine","C22804","1-Methyl-2-(4-methylsulfanyl-phenyl)-ethylamine","Q230013","Phenethylamine, α-methyl-p-(methylthio)-"],"CAS":"14116-06-4","ChEMBL":"CHEMBL6467","ChemicalClasses":["amphetamine"],"Chirality":"racemic","Classes":["Entactogen"],"Erowid Experience Reports":null,"Esters":[],"Formating":[],"HMDB ID":"HMDB0246519","HeavyAtomCount":12,"IUPACName":"1-(4-methylsulfanylphenyl)propan-2-amine","InChI":"InChI=1S/C10H15NS/c1-8(11)7-9-3-5-10(12-2)6-4-9/h3-6,8H,7,11H2,1-2H3","InChIKey":"OLEWMKVPSUCNLG-UHFFFAOYSA-N","MeSH Pharmacological Classification":"A loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. They work by a variety of mechanisms, but usually not by direct excitation of neurons. The many drugs that have such actions as side effects to their main therapeutic use are not included here. (See all compounds classified as Central Nervous System Stimulants.)","MolecularFormula":"C\u003csub\u003e10\u003c/sub\u003eH\u003csub\u003e15\u003c/sub\u003eNS","MolecularWeight":"181.30 g/mol","Opticalactivity":"( + / - )","PubChemId":151900,"Record Description":["4-Methylthioamphetamine (4-MTA) is a designer drug developed in the 1990s by a team led by David E. Nichols at Purdue University. It acts as a non-neurotoxic highly selective serotonin releasing agent (SSRA) in animals. It is distantly related to several other SSRAs, including MMAI, MDAI, and MDMAI.","Wikipedia|List of designer drugs|Empathogens|Amphetamines"],"RefCount":3,"RefCur":"","References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/4-Methylthioamphetamine","Name":"4-Methylthioamphetamine","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/151900","Name":"4-Methylthioamphetamine","Sub":false}]},{"Name":"ChEMBL","Urls":[{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6467","Name":"4-Methylthioamphetamine","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=14116-06-4","Name":"4-Methylthioamphetamine","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0246519","Name":"4-Methylthioamphetamine","Sub":false}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/C22804","Name":"4-Methylthioamphetamine","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/6JP2T8KXTR","Name":"4-Methylthioamphetamine","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID90894854","Name":"4-Methylthioamphetamine","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 151900, 4-Methylthioamphetamine. Accessed July 19, 2025. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/151900\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/151900\u003c/a\u003e","U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. 4-Methylthioamphetamine. UNII: 6JP2T8KXTR. Global Substance Registration System. Accessed July 19, 2025. \u003ca href=https://gsrs.ncats.nih.gov/ginas/app/beta/substances/6JP2T8KXTR\u003ehttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/6JP2T8KXTR\u003c/a\u003e"],"SMILES":"CC(CC1=CC=C(C=C1)SC)N","SaltData":[{"AcidCount":1,"AmineCount":1,"Formula":"Cl","Name":"hydrochloride","Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 125.646 36.568\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#3050f8\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h126v37H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"M80.228 25.87V10.63M80.228 10.63 67.029 3.01M67.029 3.01l-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M53.831 10.63 40.628 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