{"Abbreviation":"3C-E","Aliases":["Escaline","Benzeneethanamine, 4-ethoxy-3,5-dimethoxy-","3,5-Dimethoxy-4 ethoxyphenylethylamine","Ethylamine, 3,5-dimethoxy-4-ethoxyphenyl-","4-Ethoxy-3,5-dimethoxybenzeneethanamine","3,5-Methoxy-4-ethoxyphenethylamine","E","PBA20182","2-(4-Ethoxy-3,5-dimethoxy-phenyl)-ethylamine"],"CAS":"39201-82-6","ChEMBL":"CHEMBL319415","ChemicalClasses":["catecholamine"],"Chirality":"achiral","Classes":["Psychedelic"],"DrugClasses":[],"DurationOfAction":"8 – 12 hours","EliminationHalfLife":"","Erowid Experience Reports":[{"Author":"Curiosityandthecat","Id":"98257","Title":"Astoundment From a Mescaline-Virgin"}],"FullSalts":["3,5-Dimethoxy-4-ethoxyphenethylamine hydrochloride"],"HeavyAtomCount":16,"IUPACName":"2-(4-ethoxy-3,5-dimethoxyphenyl)ethanamine","InChI":"InChI=1S/C12H19NO3/c1-4-16-12-10(14-2)7-9(5-6-13)8-11(12)15-3/h7-8H,4-6,13H2,1-3H3","InChIKey":"RHOGRSKNWDNCDN-UHFFFAOYSA-N","MolecularFormula":"C\u003csub\u003e12\u003c/sub\u003eH\u003csub\u003e19\u003c/sub\u003eNO\u003csub\u003e3\u003c/sub\u003e","MolecularWeight":"225.28 g/mol","PrevSalts":["hydrochloride"],"PubChemId":38240,"Record Description":["Wikipedia|List of designer drugs|Psychedelics|Phenethylamines","Wikipedia|PiHKAL|Phenethylamines"],"RefCount":3,"References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Escaline","Name":"3,5-Dimethoxy-4-ethoxyphenethylamine","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q3057837","Name":"3,5-Dimethoxy-4-ethoxyphenethylamine","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/38240","Name":"3,5-Dimethoxy-4-ethoxyphenethylamine","Sub":false}]},{"Name":"ChEMBL","Urls":[{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL319415","Name":"3,5-Dimethoxy-4-ethoxyphenethylamine","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=39201-82-6","Name":"3,5-Dimethoxy-4-ethoxyphenethylamine","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/Q13F1C1N8I","Name":"3,5-Dimethoxy-4-ethoxyphenethylamine","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID60192455","Name":"3,5-Dimethoxy-4-ethoxyphenethylamine","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 38240, 3,5-Dimethoxy-4-ethoxyphenethylamine. Accessed June 26, 2025. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/38240\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/38240\u003c/a\u003e","U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. 3,5-Dimethoxy-4-ethoxyphenethylamine. UNII: Q13F1C1N8I. Global Substance Registration System. Accessed June 26, 2025. \u003ca href=https://gsrs.ncats.nih.gov/ginas/app/beta/substances/Q13F1C1N8I\u003ehttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/Q13F1C1N8I\u003c/a\u003e"],"SMILES":"CCOC1=C(C=C(C=C1OC)CCN)OC","Salts":["hydrochloride"],"SaltsAcidCount":[1],"SaltsAmineCount":[1],"SaltsUNII":["7L7D9XK2Y2"],"Scheduling":[],"StoreUNII":["Q13F1C1N8I"],"StructureBase64":"<svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" height="70.545mm" version="1.2" viewBox="0 0 115.936 70.545" width="115.936mm">
      
    <desc>Generated by the Chemistry Development Kit (http://github.com/cdk)</desc>
      
    <g fill="#FF0D0D" stroke="#000000" stroke-linecap="round" stroke-linejoin="round" stroke-width=".7">
            
        <rect fill="#FFFFFF" height="71.0" stroke="none" width="116.0" x=".0" y=".0"/>
            
        <g class="mol" id="mol1">
                  
            <line class="bond" id="mol1bnd1" x1="1.038" x2="14.236" y1="46.636" y2="39.016"/>
                  
            <line class="bond" id="mol1bnd2" x1="14.236" x2="24.151" y1="39.016" y2="44.741"/>
                  
            <line class="bond" id="mol1bnd3" x1="30.713" x2="40.633" y1="44.744" y2="39.016"/>
                  
            <g class="bond" id="mol1bnd4">
                        
                <line x1="40.628" x2="40.633" y1="23.768" y2="39.016"/>
                        
                <line x1="43.067" x2="43.071" y1="25.176" y2="37.609"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd5" x1="40.628" x2="53.826" y1="23.768" y2="16.148"/>
                  
            <g class="bond" id="mol1bnd6">
                        
                <line x1="67.029" x2="53.826" y1="23.776" y2="16.148"/>
                        
                <line x1="64.591" x2="53.826" y1="25.184" y2="18.964"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd7" x1="67.029" x2="67.034" y1="23.776" y2="39.025"/>
                  
            <g class="bond" id="mol1bnd8">
                        
                <line x1="53.836" x2="67.034" y1="46.645" y2="39.025"/>
                        
                <line x1="53.836" x2="64.595" y1="43.829" y2="37.617"/>
                      
            </g>
                  
            <line class="bond" id="mol1bnd9" x1="40.633" x2="53.836" y1="39.016" y2="46.645"/>
                  
            <line class="bond" id="mol1bnd10" x1="53.836" x2="53.834" y1="46.645" y2="57.964"/>
                  
            <line class="bond" id="mol1bnd11" x1="57.109" x2="67.031" y1="63.777" y2="69.507"/>
                  
            <line class="bond" id="mol1bnd12" x1="67.029" x2="80.228" y1="23.776" y2="16.156"/>
                  
            <line class="bond" id="mol1bnd13" x1="80.228" x2="93.426" y1="16.156" y2="23.776"/>
                  
            <line class="bond" id="mol1bnd14" x1="93.426" x2="103.471" y1="23.776" y2="17.977"/>
                  
            <line class="bond" id="mol1bnd15" x1="40.628" x2="30.704" y1="23.768" y2="18.041"/>
                  
            <line class="bond" id="mol1bnd16" x1="27.428" x2="27.426" y1="12.229" y2=".91"/>
                  
            <path class="atom" d="M29.694 46.633q-.0 .757 -.256 1.328q-.256 .566 -.756 .881q-.5 .316 -1.244 .316q-.756 -.0 -1.262 -.316q-.506 -.315 -.757 -.887q-.244 -.571 -.244 -1.333q.0 -.751 .244 -1.31q.251 -.566 .757 -.881q.506 -.316 1.274 -.316q.732 .0 1.232 .316q.5 .309 .756 .875q.256 .565 .256 1.327zM25.83 46.633q.0 .923 .387 1.459q.393 .53 1.221 .53q.839 -.0 1.22 -.53q.387 -.536 .387 -1.459q-.0 -.928 -.387 -1.452q-.381 -.524 -1.208 -.524q-.834 .0 -1.227 .524q-.393 .524 -.393 1.452z" id="mol1atm3" stroke="none"/>
                  
            <path class="atom" d="M56.093 61.882q-.0 .756 -.256 1.327q-.256 .566 -.756 .882q-.5 .315 -1.245 .315q-.756 .0 -1.262 -.315q-.506 -.316 -.756 -.887q-.244 -.572 -.244 -1.334q.0 -.75 .244 -1.31q.25 -.565 .756 -.881q.506 -.315 1.274 -.315q.733 -.0 1.233 .315q.5 .31 .756 .875q.256 .566 .256 1.328zM52.229 61.882q.0 .923 .387 1.458q.393 .53 1.22 .53q.84 .0 1.221 -.53q.387 -.535 .387 -1.458q-.0 -.929 -.387 -1.453q-.381 -.524 -1.209 -.524q-.833 .0 -1.226 .524q-.393 .524 -.393 1.453z" id="mol1atm10" stroke="none"/>
                  
            <g class="atom" id="mol1atm14">
                        
                <path d="M108.565 18.606h-.721l-2.619 -4.066h-.03q.012 .238 .03 .595q.024 .358 .024 .733v2.738h-.566v-4.899h.715l2.607 4.054h.03q-.006 -.107 -.018 -.328q-.012 -.22 -.024 -.476q-.006 -.262 -.006 -.482v-2.768h.578v4.899z" fill="#3050F8" stroke="none"/>
                        
                <path d="M112.871 18.606h-.619v-2.286h-2.512v2.286h-.614v-4.899h.614v2.071h2.512v-2.071h.619v4.899z" fill="#3050F8" stroke="none"/>
                        
                <path d="M115.376 20.096h-1.943v-.3l.771 -.779q.222 -.222 .372 -.393q.153 -.175 .232 -.339q.078 -.168 .078 -.365q.0 -.243 -.146 -.368q-.143 -.128 -.372 -.128q-.214 -.0 -.378 .075q-.161 .075 -.329 .207l-.193 -.243q.172 -.146 .393 -.246q.225 -.1 .507 -.1q.411 -.0 .65 .207q.24 .207 .24 .575q-.0 .229 -.097 .432q-.093 .2 -.264 .397q-.168 .196 -.393 .418l-.614 .603v.018h1.486v.329z" fill="#3050F8" stroke="none"/>
                      
            </g>
                  
            <path class="atom" d="M29.688 16.147q-.0 .756 -.256 1.328q-.256 .565 -.756 .881q-.5 .315 -1.245 .315q-.756 .0 -1.262 -.315q-.506 -.316 -.756 -.887q-.244 -.572 -.244 -1.334q.0 -.75 .244 -1.309q.25 -.566 .756 -.882q.506 -.315 1.274 -.315q.733 -.0 1.233 .315q.5 .31 .756 .876q.256 .565 .256 1.327zM25.824 16.147q.0 .923 .387 1.459q.393 .529 1.22 .529q.84 .0 1.221 -.529q.387 -.536 .387 -1.459q-.0 -.929 -.387 -1.452q-.381 -.524 -1.209 -.524q-.833 -.0 -1.226 .524q-.393 .523 -.393 1.452z" id="mol1atm15" stroke="none"/>
                
            <line class="hi" id="mol1bnd2" stroke="#FF0D0D" x1="24.151" x2="19.1935" y1="44.741" y2="41.8785"/>
            <line class="hi" id="mol1bnd3" stroke="#FF0D0D" x1="30.713" x2="35.673" y1="44.744" y2="41.879999999999995"/>
            <line class="hi" id="mol1bnd10" stroke="#FF0D0D" x1="53.834" x2="53.835" y1="57.964" y2="52.304500000000004"/>
            <line class="hi" id="mol1bnd11" stroke="#FF0D0D" x1="57.109" x2="62.07000000000001" y1="63.777" y2="66.642"/>
            <line class="hi" id="mol1bnd14" stroke="#3050F8" x1="103.471" x2="98.4485" y1="17.977" y2="20.8765"/>
            <line class="hi" id="mol1bnd15" stroke="#FF0D0D" x1="30.704" x2="35.666" y1="18.041" y2="20.9045"/>
            <line class="hi" id="mol1bnd16" stroke="#FF0D0D" x1="27.428" x2="27.427" y1="12.229" y2="6.5695"/>
        </g>
          
    </g>
    
</svg>
","Subjective Effects":null,"Title":"3,5-Dimethoxy-4-ethoxyphenethylamine","UNII":"Q13F1C1N8I","Wikidata":"Q3057837","Wikipedia":"Escaline","XLogP":1.2}