{"Abbreviation":["MDPV","MDPK"],"Aliases":["Methylenedioxypyrovalerone","MDPV","3,4-methylenedioxypyrovalerone","MDPK","(3,4)-methylenedioxypyrovalerone","1-Pentanone, 1-(1,3-benzodioxol-5-yl)-2-(1-pyrrolidinyl)-","J2.658.826j","Chebi:233286","1-(2H-1,3-benzodioxol-5-yl)-2-(pyrrolidin-1-yl)pentan-1-one","MPDV cpd","Pyrovalerone, methylendioxy-","Ivory Wave","Energy 1","Epitope ID:2279523","DEA No. 7535","3,4-Methylenedioxy Pyrovalerone","Schembl15161948","Schembl29379296","HSDB 7980","1-(Benzo[d][1,3]dioxol-5-yl)-2-(pyrrolidin-1-yl)pentan-1-one","NS00008153","C22808","1-(1,3-benzodioxol-5-yl)-2-(pyrrolidin-1-yl)pentan-1-one","1-(3,4-Methylenedioxyphenyl)-2-(pyrrolidin-1-yl)pentan-1-one","1-(benzo[d][1,3]dioxol-5-yl)-2-(pyrrolidin-1-yl)pentan-1-one"],"CAS":"687603-66-3","ChemicalClasses":["3,4-methylenedioxyphenethylamine","pyrrolidinophenone"],"Chirality":"racemic","Classes":["Stimulant"],"Color/Form":"White or light tan powder","DTXSID":"90897461","Druglikeness":{"Lipinski":{"Passes":true,"Violations":0}},"Erowid Experience Reports":[],"Esters":[],"Formating":["3',4'-methylenedioxy-alpha-pyrrolidinopentiophenone"],"HMDB ID":"HMDB0254640","HeavyAtomCount":20,"IUPACName":"1-(1,3-benzodioxol-5-yl)-2-pyrrolidin-1-ylpentan-1-one","InChI":"InChI=1S/C16H21NO3/c1-2-5-13(17-8-3-4-9-17)16(18)12-6-7-14-15(10-12)20-11-19-14/h6-7,10,13H,2-5,8-9,11H2,1H3","InChIKey":"SYHGEUNFJIGTRX-UHFFFAOYSA-N","MeSH Headers":[{"Id":"M0553192","Link":"https://id.nlm.nih.gov/mesh/M0553192.html","Name":"3,4-Methylenedioxypyrovalerone","Ref":29},{"Id":"DescTree","Link":"https://www.nlm.nih.gov/mesh/meshhome.html","Name":"MeSH Tree","Ref":30},{"Id":"M0001063","Link":"https://id.nlm.nih.gov/mesh/M0001063.html","Name":"Central Nervous System Stimulants","Ref":42}],"MeSH Pharmacological Classification":[{"Id":"M0001063","Link":"https://id.nlm.nih.gov/mesh/M0001063.html","Name":"Central Nervous System Stimulant","Ref":42}],"Melting Point":"MW 311.80; MP: 238-239 °C with decomposition; Soluble in chloroform, methanol, deionized water /3,4-Methylenedioxypyrovalerone hydrochloride/","Metabolism/Metabolites":"The metabolism of methylenedioxypyrovalerone  (MDPV) was evaluated in vitro using human liver microsomes and S9 cellular fractions for CYP450 phase I and uridine 5'-diphosphoglucuronosyltransferase (UGT) and sulfotransferase (SULT) phase II metabolism studies. The resulting metabolites were subsequently liquid/liquid extracted and analyzed using gas chromatography/mass spectrometry (GC/MS) as trimethylsilyl (TMS) derivatives. The structures of the metabolites were further confirmed by accurate mass measurement using a liquid chromatography/quadrupole time-of-flight (LC/QTOF) mass spectrometer. The studies demonstrated that the main metabolites of MDPV are catechol and methyl catechol pyrovalerone, which are in turn sulfated and glucuronated. ...","MolecularFormula":"C\u003csub\u003e16\u003c/sub\u003eH\u003csub\u003e21\u003c/sub\u003eNO\u003csub\u003e3\u003c/sub\u003e","MolecularWeight":"275.34 g/mol","PD":"PD021354","Passes":true,"PubChemId":20111961,"PubChemTitle":"Methylenedioxypyrovalerone","Reddit Experience Reports":[],"RefChem":"389299","RefCount":3,"RefCur":"","References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Methylenedioxypyrovalerone","Name":"3',4'-Methylenedioxy-α-pyrrolidinopentiophenone","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q417010","Name":"3',4'-Methylenedioxy-α-pyrrolidinopentiophenone","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/20111961","Name":"3',4'-Methylenedioxy-α-pyrrolidinopentiophenone","Sub":false}]},{"Name":"Probes \u0026 Drugs","Urls":[{"Link":"https://www.probes-drugs.org/compound/PD021354","Name":"3',4'-Methylenedioxy-α-pyrrolidinopentiophenone","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=687603-66-3","Name":"3',4'-Methylenedioxy-α-pyrrolidinopentiophenone","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0254640","Name":"3',4'-Methylenedioxy-α-pyrrolidinopentiophenone","Sub":false}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/C22808","Name":"3',4'-Methylenedioxy-α-pyrrolidinopentiophenone","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/E7LD6JMR0L","Name":"3',4'-Methylenedioxy-α-pyrrolidinopentiophenone","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID90897461","Name":"3',4'-Methylenedioxy-α-pyrrolidinopentiophenone","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 20111961, 3',4'-Methylenedioxy-α-pyrrolidinopentiophenone. Accessed July 3, 2026. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/20111961\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/20111961\u003c/a\u003e","Substance Details 3,4-Methylenedioxypyrovalerone. Accessed July 3, 2026. \u003ca href=https://www.unodc.org/LSS/Substance/Details/6a35fe21-2cdd-46ff-a343-cd977fa28ff6\u003ehttps://www.unodc.org/LSS/Substance/Details/6a35fe21-2cdd-46ff-a343-cd977fa28ff6\u003c/a\u003e"],"SMILES":"CCCC(C(=O)C1=CC2=C(C=C1)OCO2)N3CCCC3","SaltData":[],"Salts":[],"Scheduling":[{"gov":"Australia","ref":[],"schedule":"S9 substance"},{"gov":"Brazil","ref":[],"schedule":"F1 substance"},{"gov":"Canada","ref":[],"schedule":"Schedule I substance"},{"gov":"Germany","ref":[],"schedule":"Anlage II substance"},{"gov":"United Kingdom","ref":[],"schedule":"Class B substance"},{"act":"Controlled Substances Act (CSA)","gov":"United States","ref":[],"schedule":"Schedule I"},{"act":"Convention on Psychotropic Substances 1971","gov":"United Nations","ref":["2"],"schedule":"Schedule II drug"}],"StereoisomerData":[{"ChemicalClasses":["3,4-methylenedioxyphenethylamine","pyrrolidinophenone"],"SMILES":"CCC[C@H](C(=O)C1=CC2=C(C=C1)OCO2)N1CCCC1","Structure":"\u003csvg 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class=\"bond\"/\u003e\u003cpath stroke=\"none\" d=\"M64.171 2.155q-.738 0-1.173.554-.429.548-.429 1.494 0 .947.429 1.495.435.547 1.173.547t1.167-.547q.428-.548.428-1.495 0-.946-.428-1.494-.429-.554-1.167-.554m0-.547q1.054 0 1.679.708.631.703.631 1.887 0 1.179-.631 1.888-.625.702-1.679.702t-1.685-.702q-.631-.703-.631-1.888 0-1.184.631-1.887.631-.708 1.685-.708M10.082 44.965q-.738 0-1.173.553-.428.548-.428 1.495 0 .946.428 1.494.435.548 1.173.548t1.167-.548.428-1.494q0-.947-.428-1.495-.429-.553-1.167-.553m0-.548q1.054 0 1.679.709.631.702.631 1.887 0 1.178-.631 1.887-.625.702-1.679.702T8.397 48.9q-.631-.703-.631-1.887t.631-1.887q.631-.709 1.685-.709M10.074 20.307q-.738 0-1.173.554-.428.547-.428 1.494 0 .946.428 1.494.435.548 1.173.548t1.167-.548.428-1.494q0-.947-.428-1.494-.429-.554-1.167-.554m0-.548q1.054 0 1.679.709.631.702.631 1.887 0 1.179-.631 1.887-.625.703-1.679.703t-1.685-.703-.631-1.887.631-1.887q.631-.709 1.685-.709\" class=\"atom\"/\u003e\u003cpath fill=\"#3050f8\" stroke=\"none\" d=\"M88.671 16.94h.911l2.215 4.185V16.94h.66v5.001h-.91l-2.221-4.185v4.185h-.655z\" class=\"atom\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"m13.914 45.764 5.33-1.732M7.627 43.637 4.373 39.16M7.62 25.728l-3.25 4.478M13.906 23.595l5.331 1.728\" class=\"hi\"/\u003e\u003cpath stroke=\"#3050f8\" d=\"m87.285 21.333-4.959 2.864M90.996 15.349l.582-5.513M93.92 20.932l5.267 2.342\" class=\"hi\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Subjective Effects":{"Cognitive Effects":["Analysis enhancement","Ego inflation","Focus enhancement","Increased music appreciation","Motivation enhancement","Thought acceleration","Wakefulness","Disinhibition","Suggestibility suppression","Cognitive euphoria","Compulsive redosing","Mania"],"Physical Effects":["Increased libido","Stamina enhancement","Stimulation","Appetite suppression","Dehydration","Dry mouth","Restless legs","Shakiness","Teeth grinding","Abnormal heartbeat","Increased blood pressure","Increased heart rate","Vasoconstriction"],"Visual Effects":[]},"Title":"3',4'-Methylenedioxy-α-pyrrolidinopentiophenone","UNII":"E7LD6JMR0L","Violations":0,"Wikidata":"Q417010","Wikipedia":"Methylenedioxypyrovalerone","XLogP":3.3}