{"Abbreviation":["25E-NBOMe"],"Aliases":["2,5-Dimethoxy-4-ethyl-N-(2-methoxybenzyl)phenethylamine","2c-E-Nbome","2-(2,5-Dimethoxy-4-ethylphenyl)-N-(2-methoxybenzyl)ethanamine","Benzeneethanamine, 4-ethyl-2,5-dimethoxy-N-((2-methoxyphenyl)methyl)-","RefChem:1070625","4-Ethyl-2,5-dimethoxy-N-((2-methoxyphenyl)methyl)benzeneethanamine","25E-Nbome","EEC63214","2-(4-Ethyl-2,5-dimethoxyphenyl)-N-[(2-methoxybenzyl)]ethylamine hydrochloride"],"CAS":"1354632-14-6","ChemicalClasses":["N-(2-methoxybenzyl)phenethylamine"],"Chirality":"achiral","Classes":["Psychedelic"],"Esters":[],"Formating":[],"HeavyAtomCount":24,"IUPACName":"2-(4-ethyl-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine","InChI":"InChI=1S/C20H27NO3/c1-5-15-12-20(24-4)16(13-19(15)23-3)10-11-21-14-17-8-6-7-9-18(17)22-2/h6-9,12-13,21H,5,10-11,14H2,1-4H3","InChIKey":"PXDVGFGXPVCNAB-UHFFFAOYSA-N","MolecularFormula":"C\u003csub\u003e20\u003c/sub\u003eH\u003csub\u003e27\u003c/sub\u003eNO\u003csub\u003e3\u003c/sub\u003e","MolecularWeight":"329.4 g/mol","PD":"PD047109","PubChemId":118796522,"Record Description":["Wikipedia|List of designer drugs|Psychedelics|NBxx"],"RefCount":4,"RefCur":"","References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/25E-NBOMe","Name":"2,5-Dimethoxy-4-ethyl-N-(2-methoxybenzyl)phenethylamine","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q16154823","Name":"2,5-Dimethoxy-4-ethyl-N-(2-methoxybenzyl)phenethylamine","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/118796522","Name":"2,5-Dimethoxy-4-ethyl-N-(2-methoxybenzyl)phenethylamine","Sub":false}]},{"Name":"Probes \u0026 Drugs","Urls":[{"Link":"https://www.probes-drugs.org/compound/PD047109","Name":"2,5-Dimethoxy-4-ethyl-N-(2-methoxybenzyl)phenethylamine","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=1354632-14-6","Name":"2,5-Dimethoxy-4-ethyl-N-(2-methoxybenzyl)phenethylamine","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/02HX6G35T3","Name":"2,5-Dimethoxy-4-ethyl-N-(2-methoxybenzyl)phenethylamine","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID901014188","Name":"2,5-Dimethoxy-4-ethyl-N-(2-methoxybenzyl)phenethylamine","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 118796522, 2,5-Dimethoxy-4-ethyl-N-(2-methoxybenzyl)phenethylamine. Accessed October 5, 2025. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/118796522\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/118796522\u003c/a\u003e","U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. 2,5-Dimethoxy-4-ethyl-N-(2-methoxybenzyl)phenethylamine. UNII: 02HX6G35T3. Global Substance Registration System. Accessed October 5, 2025. \u003ca href=https://gsrs.ncats.nih.gov/ginas/app/beta/substances/02HX6G35T3\u003ehttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/02HX6G35T3\u003c/a\u003e","Anvisa. RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. July 24, 2023. Accessed October 5, 2025. \u003ca href=https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-804-de-24-de-julho-de-2023-498447451\u003ehttps://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-804-de-24-de-julho-de-2023-498447451\u003c/a\u003e"],"SMILES":"CCC1=CC(=C(C=C1OC)CCNCC2=CC=CC=C2OC)OC","SaltData":[{"AcidCount":1,"Amine":"2,5-Dimethoxy-4-ethyl-N-(2-methoxybenzyl)phenethylamine","AmineCount":1,"Formula":"Cl","Name":"hydrochloride","Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 170.197 78.308\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#ff0d0d\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h171v79H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"m1.038 46.794 13.2 7.618M14.238 54.412l13.197-7.622\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M27.435 31.55v15.24M29.873 32.958v12.424\"/\u003e\u003c/g\u003e\u003cpath d=\"m27.435 31.55 13.208-7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m53.851 31.55-13.208-7.62M51.412 32.958l-10.769-6.213\"/\u003e\u003c/g\u003e\u003cpath d=\"M53.851 31.55v15.24\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m40.643 54.41 13.208-7.62M40.643 51.595l10.769-6.213\"/\u003e\u003c/g\u003e\u003cpath d=\"m27.435 46.79 13.208 7.62M40.643 54.41v11.319M43.918 71.541l9.923 5.729M53.851 31.55l13.197-7.622M67.048 23.928l13.199 7.618M80.247 31.546l10.044-5.801M96.597 25.744l10.047 5.798M106.644 31.542l13.197-7.623\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M119.841 8.671v15.248M122.279 10.078v12.433\"/\u003e\u003c/g\u003e\u003cpath d=\"m119.841 8.671 13.2-7.633\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m146.242 8.654-13.201-7.616M143.803 10.062l-10.76-6.208\"/\u003e\u003c/g\u003e\u003cpath d=\"M146.242 8.654v15.248\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m133.041 31.535 13.201-7.633M133.04 28.719l10.763-6.223\"/\u003e\u003c/g\u003e\u003cpath d=\"m119.841 23.919 13.2 7.616M133.041 31.535l.006 11.319M136.325 48.665l9.925 5.724M40.643 23.93V12.611M37.359 6.794 27.444 1.07\" class=\"bond\"/\u003e\u003cpath stroke=\"none\" d=\"M42.902 69.647q0 .756-.256 1.328-.256.565-.756.881-.5.315-1.244.315-.756 0-1.262-.315-.506-.316-.757-.887-.244-.572-.244-1.334 0-.75.244-1.31.251-.565.757-.881.506-.315 1.273-.315.733 0 1.233.315.5.31.756.875.256.566.256 1.328m-3.864 0q0 .923.387 1.459.393.529 1.221.529.839 0 1.22-.529.387-.536.387-1.459 0-.929-.387-1.453-.381-.523-1.209-.523-.833 0-1.226.523-.393.524-.393 1.453\" class=\"atom\"/\u003e\u003cg fill=\"#3050f8\" stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M95.385 26.373h-.721l-2.619-4.066h-.03l.03.596q.024.357.024.732v2.738h-.566v-4.899h.715l2.607 4.054h.03l-.018-.327-.024-.477q-.006-.262-.006-.482v-2.768h.578zM95.248 20.912h-.619v-2.286h-2.512v2.286h-.614v-4.899h.614v2.072h2.512v-2.072h.619z\"/\u003e\u003c/g\u003e\u003cpath stroke=\"none\" d=\"M135.308 46.772q0 .756-.256 1.328-.256.565-.756.881-.5.315-1.245.315-.756 0-1.262-.315-.506-.316-.756-.887-.244-.572-.244-1.334 0-.75.244-1.309.25-.566.756-.881t1.274-.316q.733 0 1.233.316.5.309.756.875.256.565.256 1.327m-3.864 0q0 .923.387 1.459.393.53 1.22.53.84 0 1.221-.53.387-.536.387-1.459 0-.928-.387-1.452-.381-.524-1.209-.524-.833 0-1.226.524t-.393 1.452M42.902 8.687q0 .756-.256 1.328-.256.565-.756.881-.5.315-1.244.315-.756 0-1.262-.315-.506-.316-.757-.887-.244-.572-.244-1.334 0-.75.244-1.31.251-.565.757-.881.506-.315 1.273-.315.733 0 1.233.315.5.31.756.875.256.566.256 1.328m-3.864 0q0 .923.387 1.459.393.529 1.221.529.839 0 1.22-.529.387-.536.387-1.459 0-.929-.387-1.453-.381-.523-1.209-.523-.833 0-1.226.523-.393.524-.393 1.453\" class=\"atom\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"M40.643 65.729v-5.66M43.918 71.541l4.962 2.864\" class=\"hi\"/\u003e\u003cpath stroke=\"#3050f8\" d=\"m90.291 25.745-5.022 2.9M90.291 25.745l-5.022 2.9M96.597 25.744l5.023 2.899M96.597 25.744l5.023 2.899\" class=\"hi\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"m133.047 42.854-.003-5.66M136.325 48.665l4.962 2.862M40.643 12.611v5.659M37.359 6.794l-4.958-2.862\" class=\"hi\"/\u003e\u003c/g\u003e\u003cg class=\"mol\"\u003e\u003cg fill=\"#1ff01f\" stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M166.88 37.303q-.786 0-1.238.529-.452.524-.452 1.447 0 .911.416 1.447.423.53 1.268.53.322 0 .607-.054.292-.06.566-.143v.536q-.274.101-.566.149-.291.053-.696.053-.744 0-1.25-.309-.5-.31-.75-.875-.25-.572-.25-1.34 0-.744.268-1.31.273-.565.803-.881.53-.321 1.28-.321.78 0 1.352.286l-.245.524q-.226-.102-.506-.185-.273-.083-.607-.083m2.757 4.423h-.601v-5.215h.601zM163.973 41.726h-.619V39.44h-2.512v2.286h-.613v-4.9h.613v2.072h2.512v-2.072h.619z\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Title":"2,5-Dimethoxy-4-ethyl-N-(2-methoxybenzyl)phenethylamine hydrochloride","UNII":"J52VLQ75U2"}],"Salts":["hydrochloride"],"Scheduling":[{"gov":"Brazil","ref":["3"],"schedule":"F2 substance"},{"act":"Neue-psychoaktive-Stoffe-Gesetz (NpSG)","gov":"Germany","ref":[],"schedule":"Neuer-Psychoaktiver-Stoff"},{"gov":"United Kingdom","ref":[],"schedule":"Class A substance"}],"StereoisomerData":[],"Stereoisomers":[],"Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 147.289 78.308\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#ff0d0d\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h148v79H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"m1.038 46.794 13.2 7.618M14.238 54.412l13.197-7.622\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M27.435 31.55v15.24M29.873 32.958v12.424\"/\u003e\u003c/g\u003e\u003cpath d=\"m27.435 31.55 13.208-7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m53.851 31.55-13.208-7.62M51.412 32.958l-10.769-6.213\"/\u003e\u003c/g\u003e\u003cpath d=\"M53.851 31.55v15.24\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m40.643 54.41 13.208-7.62M40.643 51.595l10.769-6.213\"/\u003e\u003c/g\u003e\u003cpath d=\"m27.435 46.79 13.208 7.62M40.643 54.41v11.319M43.918 71.541l9.923 5.729M53.851 31.55l13.197-7.622M67.048 23.928l13.199 7.618M80.247 31.546l10.044-5.801M96.597 25.744l10.047 5.798M106.644 31.542l13.197-7.623\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M119.841 8.671v15.248M122.279 10.078v12.433\"/\u003e\u003c/g\u003e\u003cpath d=\"m119.841 8.671 13.2-7.633\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m146.242 8.654-13.201-7.616M143.803 10.062l-10.76-6.208\"/\u003e\u003c/g\u003e\u003cpath d=\"M146.242 8.654v15.248\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m133.041 31.535 13.201-7.633M133.04 28.719l10.763-6.223\"/\u003e\u003c/g\u003e\u003cpath d=\"m119.841 23.919 13.2 7.616M133.041 31.535l.006 11.319M136.325 48.665l9.925 5.724M40.643 23.93V12.611M37.359 6.794 27.444 1.07\" class=\"bond\"/\u003e\u003cpath stroke=\"none\" d=\"M42.902 69.647q0 .756-.256 1.328-.256.565-.756.881-.5.315-1.244.315-.756 0-1.262-.315-.506-.316-.757-.887-.244-.572-.244-1.334 0-.75.244-1.31.251-.565.757-.881.506-.315 1.273-.315.733 0 1.233.315.5.31.756.875.256.566.256 1.328m-3.864 0q0 .923.387 1.459.393.529 1.221.529.839 0 1.22-.529.387-.536.387-1.459 0-.929-.387-1.453-.381-.523-1.209-.523-.833 0-1.226.523-.393.524-.393 1.453\" class=\"atom\"/\u003e\u003cg fill=\"#3050f8\" stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M95.385 26.373h-.721l-2.619-4.066h-.03l.03.596q.024.357.024.732v2.738h-.566v-4.899h.715l2.607 4.054h.03l-.018-.327-.024-.477q-.006-.262-.006-.482v-2.768h.578zM95.248 20.912h-.619v-2.286h-2.512v2.286h-.614v-4.899h.614v2.072h2.512v-2.072h.619z\"/\u003e\u003c/g\u003e\u003cpath stroke=\"none\" d=\"M135.308 46.772q0 .756-.256 1.328-.256.565-.756.881-.5.315-1.245.315-.756 0-1.262-.315-.506-.316-.756-.887-.244-.572-.244-1.334 0-.75.244-1.309.25-.566.756-.881t1.274-.316q.733 0 1.233.316.5.309.756.875.256.565.256 1.327m-3.864 0q0 .923.387 1.459.393.53 1.22.53.84 0 1.221-.53.387-.536.387-1.459 0-.928-.387-1.452-.381-.524-1.209-.524-.833 0-1.226.524t-.393 1.452M42.902 8.687q0 .756-.256 1.328-.256.565-.756.881-.5.315-1.244.315-.756 0-1.262-.315-.506-.316-.757-.887-.244-.572-.244-1.334 0-.75.244-1.31.251-.565.757-.881.506-.315 1.273-.315.733 0 1.233.315.5.31.756.875.256.566.256 1.328m-3.864 0q0 .923.387 1.459.393.529 1.221.529.839 0 1.22-.529.387-.536.387-1.459 0-.929-.387-1.453-.381-.523-1.209-.523-.833 0-1.226.523-.393.524-.393 1.453\" class=\"atom\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"M40.643 65.729v-5.66M43.918 71.541l4.962 2.864\" class=\"hi\"/\u003e\u003cpath stroke=\"#3050f8\" d=\"m90.291 25.745-5.022 2.9M90.291 25.745l-5.022 2.9M96.597 25.744l5.023 2.899M96.597 25.744l5.023 2.899\" class=\"hi\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"m133.047 42.854-.003-5.66M136.325 48.665l4.962 2.862M40.643 12.611v5.659M37.359 6.794l-4.958-2.862\" class=\"hi\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Subjective Effects":null,"Title":"2,5-Dimethoxy-4-ethyl-N-(2-methoxybenzyl)phenethylamine","UNII":"02HX6G35T3","Wikidata":"Q16154823","Wikipedia":"25E-NBOMe","XLogP":4}